메뉴 건너뛰기




Volumn 25, Issue 6, 2015, Pages 858-871

Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN CELF1; PROTEIN CELF2; PROTEIN MBNL1; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; CELF PROTEIN; CELF1 PROTEIN; CELF1 PROTEIN, HUMAN; CELF2 PROTEIN, HUMAN; ISOPROTEIN; MBNL1 PROTEIN, HUMAN; MBNL2 PROTEIN, HUMAN; NERVE PROTEIN; TRANSCRIPTOME;

EID: 84931829028     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.184390.114     Document Type: Article
Times cited : (154)

References (58)
  • 1
    • 28544440718 scopus 로고    scopus 로고
    • RNA-dependent integrin α3 protein localization regulated by the Muscleblind-like protein MLP1
    • Adereth Y, Dammai V, Kose N, Li R, Hsu T. 2005. RNA-dependent integrin α3 protein localization regulated by the Muscleblind-like protein MLP1. Nat Cell Biol 7: 1240-1247.
    • (2005) Nat Cell Biol , vol.7 , pp. 1240-1247
    • Adereth, Y.1    Dammai, V.2    Kose, N.3    Li, R.4    Hsu, T.5
  • 3
    • 33744980908 scopus 로고    scopus 로고
    • Mammalian CELF/Bruno-like RNA-binding proteins: Molecular characteristics and biological functions
    • Barreau C, Paillard L, Mereau A, Osborne HB. 2006. Mammalian CELF/Bruno-like RNA-binding proteins: molecular characteristics and biological functions. Biochimie 88: 515-525.
    • (2006) Biochimie , vol.88 , pp. 515-525
    • Barreau, C.1    Paillard, L.2    Mereau, A.3    Osborne, H.B.4
  • 5
    • 0036203307 scopus 로고    scopus 로고
    • Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing
    • Charlet BN, Logan P, Singh G, Cooper TA. 2002. Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing. Mol Cell 9: 649-658.
    • (2002) Mol Cell , vol.9 , pp. 649-658
    • Charlet, B.N.1    Logan, P.2    Singh, G.3    Cooper, T.A.4
  • 6
    • 84858440814 scopus 로고    scopus 로고
    • The importanceof CELF control: Molecular and biological roles of the CUG-BP Elav-like family of RNA-binding proteins
    • Dasgupta T, Ladd AN. 2012.The importanceof CELF control: molecular and biological roles of the CUG-BP, Elav-like family of RNA-binding proteins. Wiley Interdiscip Rev RNA 3: 104-121.
    • (2012) Wiley Interdiscip Rev RNA , vol.3 , pp. 104-121
    • Dasgupta, T.1    Ladd, A.N.2
  • 7
    • 70149109214 scopus 로고    scopus 로고
    • The CUGBP2 splicing factor regulates an ensemble ofbranchpoints from perimeter binding sites with implications for autoregulation
    • Dembowski JA, Grabowski PJ. 2009. The CUGBP2 splicing factor regulates an ensemble ofbranchpoints from perimeter binding sites with implications for autoregulation. PLoS Genet 5: e1000595.
    • (2009) PLoS Genet , vol.5 , pp. e1000595
    • Dembowski, J.A.1    Grabowski, P.J.2
  • 10
    • 12844278103 scopus 로고    scopus 로고
    • Identification of putative new splicing targets for ETR-3 using sequences identified by systematic evolution of ligands by exponential enrichment
    • Faustino NA, Cooper TA. 2005. Identification of putative new splicing targets for ETR-3 using sequences identified by systematic evolution of ligands by exponential enrichment. Mol Cell Biol 25: 879-887.
    • (2005) Mol Cell Biol , vol.25 , pp. 879-887
    • Faustino, N.A.1    Cooper, T.A.2
  • 13
    • 67949097422 scopus 로고    scopus 로고
    • CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA
    • Goo YH, Cooper TA. 2009. CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA. Nucleic Acids Res 37: 4275-4286.
    • (2009) Nucleic Acids Res , vol.37 , pp. 4275-4286
    • Goo, Y.H.1    Cooper, T.A.2
  • 15
    • 19144365784 scopus 로고    scopus 로고
    • Identification of CELF splicing activation and repression domains in vivo
    • Han J, Cooper TA. 2005. Identification of CELF splicing activation and repression domains in vivo. Nucleic Acids Res 33: 2769-2780.
    • (2005) Nucleic Acids Res , vol.33 , pp. 2769-2780
    • Han, J.1    Cooper, T.A.2
  • 17
    • 23744450059 scopus 로고    scopus 로고
    • Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy
    • Ho TH, Savkur RS, Poulos MG, Mancini MA, Swanson MS, Cooper TA. 2005. Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy. J Cell Sci 118: 2923-2933.
    • (2005) J Cell Sci , vol.118 , pp. 2923-2933
    • Ho, T.H.1    Savkur, R.S.2    Poulos, M.G.3    Mancini, M.A.4    Swanson, M.S.5    Cooper, T.A.6
  • 19
    • 66049104920 scopus 로고    scopus 로고
    • ′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development
    • ′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development. Proc Natl Acad Sci 106: 7028-7033.
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 7028-7033
    • Ji, Z.1    Lee, J.Y.2    Pan, Z.3    Jiang, B.4    Tian, B.5
  • 21
    • 77950513681 scopus 로고    scopus 로고
    • MicroRNAs coordinatean alternative splicing network during mouse postnatal heart development
    • Kalsotra A, Wang K, Li PF, Cooper TA. 2010. MicroRNAs coordinatean alternative splicing network during mouse postnatal heart development. Genes Dev 24: 653-658.
    • (2010) Genes Dev , vol.24 , pp. 653-658
    • Kalsotra, A.1    Wang, K.2    Li, P.F.3    Cooper, T.A.4
  • 22
    • 84895907629 scopus 로고    scopus 로고
    • The Mef2 transcription network is disrupted in myotonic dystrophy heart tissue, dramatically altering miRNA and mRNA expression
    • KalsotraA, Singh RK, GurhaP, Ward AJ, Creighton CJ, Cooper TA. 2014. The Mef2 transcription network is disrupted in myotonic dystrophy heart tissue, dramatically altering miRNA and mRNA expression. Cell Rep 6: 336-345.
    • (2014) Cell Rep , vol.6 , pp. 336-345
    • Kalsotraa Singh, R.K.1    Gurhap Ward, A.J.2    Creighton, C.J.3    Cooper, T.A.4
  • 23
    • 78649714014 scopus 로고    scopus 로고
    • Analysis and design of RNA sequencing experiments for identifying isoform regulation
    • Katz Y, Wang ET, Airoldi EM, Burge CB. 2010. Analysis and design of RNA sequencing experiments for identifying isoform regulation. Nat Methods 7: 1009-1015.
    • (2010) Nat Methods , vol.7 , pp. 1009-1015
    • Katz, Y.1    Wang, E.T.2    Airoldi, E.M.3    Burge, C.B.4
  • 24
    • 79959813870 scopus 로고    scopus 로고
    • A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins
    • KishoreS, Jaskiewicz L, Burger L, Hausser J, Khorshid M, Zavolan M. 2011. A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins. Nat Methods 8: 559-564.
    • (2011) Nat Methods , vol.8 , pp. 559-564
    • Kishores Jaskiewicz, L.1    Burger, L.2    Hausser, J.3    Khorshid, M.4    Zavolan, M.5
  • 25
    • 77950658740 scopus 로고    scopus 로고
    • Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1
    • Koshelev M, Sarma S, Price RE, Wehrens XHT, Cooper TA. 2010. Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1. Hum Mol Genet 19: 1066-1075.
    • (2010) Hum Mol Genet , vol.19 , pp. 1066-1075
    • Koshelev, M.1    Sarma, S.2    Price, R.E.3    Xht, W.4    Cooper, T.A.5
  • 26
    • 34948834723 scopus 로고    scopus 로고
    • Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation
    • Kuyumcu-Martinez NM, Wang GS, Cooper TA. 2007. Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation. Mol Cell 28: 68-78.
    • (2007) Mol Cell , vol.28 , pp. 68-78
    • Kuyumcu-Martinez, N.M.1    Wang, G.S.2    Cooper, T.A.3
  • 27
    • 84884814617 scopus 로고    scopus 로고
    • CUG-BP Elav-like family (CELF)-mediated alternative splicing regulation in the brain during health and disease
    • Ladd AN. 2013. CUG-BP, Elav-like family (CELF)-mediated alternative splicing regulation in the brain during health and disease. Mol Cell Neurosci 56: 456-464.
    • (2013) Mol Cell Neurosci , vol.56 , pp. 456-464
    • Ladd, A.N.1
  • 28
    • 20444443019 scopus 로고    scopus 로고
    • Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development
    • Ladd AN, Stenberg MG, Swanson MS, Cooper TA. 2005. Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development. Dev Dyn 233: 783-793.
    • (2005) Dev Dyn , vol.233 , pp. 783-793
    • Ladd, A.N.1    Stenberg, M.G.2    Swanson, M.S.3    Cooper, T.A.4
  • 29
    • 84901913783 scopus 로고    scopus 로고
    • RNA Bind-n-Seq: Quantitative assessment ofthe sequence and structural binding specificity of RNA binding proteins
    • Lambert N, Robertson A, Jangi M, McGeary S, Sharp PA, Burge CB. 2014. RNA Bind-n-Seq: quantitative assessment ofthe sequence and structural binding specificity of RNA binding proteins. Mol Cell 54: 887-900.
    • (2014) Mol Cell , vol.54 , pp. 887-900
    • Lambert, N.1    Robertson, A.2    Jangi, M.3    McGeary, S.4    Sharp, P.A.5    Burge, C.B.6
  • 30
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B, Trapnell C, Pop M, Salzberg SL. 2009. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10: R25.
    • (2009) Genome Biol , vol.10 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 31
    • 77955291454 scopus 로고    scopus 로고
    • Systematic analysis of cis-elements in unstable mRNAs demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cells
    • Lee JE, Lee JY, Wilusz J, Tian B, Wilusz CJ. 2010. Systematic analysis of cis-elements in unstable mRNAs demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cells. PLoS One 5: e11201.
    • (2010) PLoS One , vol.5 , pp. e11201
    • Lee, J.E.1    Lee, J.Y.2    Wilusz, J.3    Tian, B.4    Wilusz, C.J.5
  • 35
    • 0036347525 scopus 로고    scopus 로고
    • Expanded CUG repeats trigger aberrant splicingof ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy
    • Mankodi A, Takahashi MP, Jiang H, Beck CL, Bowers WJ, Moxley RT, Cannon SC, Thornton CA. 2002. Expanded CUG repeats trigger aberrant splicingof ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy. Mol Cell 10: 35-44.
    • (2002) Mol Cell , vol.10 , pp. 35-44
    • Mankodi, A.1    Takahashi, M.P.2    Jiang, H.3    Beck, C.L.4    Bowers, W.J.5    Moxley, R.T.6    Cannon, S.C.7    Thornton, C.A.8
  • 38
    • 18344364099 scopus 로고    scopus 로고
    • Understanding alternative splicing: Towards a cellular code
    • Matlin AJ, Clark F, Smith CWJ. 2005.Understanding alternative splicing: towards a cellular code. Nat Rev Mol Cell Biol 6: 386-398.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 386-398
    • Matlin, A.J.1    Clark, F.2    Smith, C.W.J.3
  • 40
    • 0038377392 scopus 로고    scopus 로고
    • A functional deadeny-lation assay identifies human CUG-BP as a deadenylation factor
    • Paillard L, Legagneux V, Beverley Osborne H. 2003. A functional deadeny-lation assay identifies human CUG-BP as a deadenylation factor. Biol Cell 95: 107-113.
    • (2003) Biol Cell , vol.95 , pp. 107-113
    • Paillard, L.1    Legagneux, V.2    Beverley Osborne, H.3
  • 41
    • 0032076126 scopus 로고    scopus 로고
    • Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy
    • Philips AV, Timchenko LT, Cooper TA. 1998. Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy. Science 280: 737-741.
    • (1998) Science , vol.280 , pp. 737-741
    • Philips, A.V.1    Timchenko, L.T.2    Cooper, T.A.3
  • 44
    • 77953176036 scopus 로고    scopus 로고
    • A scaling normalization method for differential expression analysis of RNA-seq data
    • Robinson MD, Oshlack A. 2010. A scaling normalization method for differential expression analysis of RNA-seq data. Genome Biol 11: R25.
    • (2010) Genome Biol , vol.11 , pp. R25
    • Robinson, M.D.1    Oshlack, A.2
  • 45
    • 23744484618 scopus 로고    scopus 로고
    • ′ splice site-dependent assembly ofU2AF and the prespliceo-somal e complex
    • ′ splice site-dependent assembly ofU2AF and the prespliceo-somal E complex. Mol Cell 19: 485-496.
    • (2005) Mol Cell , vol.19 , pp. 485-496
    • Sharma, S.1    Falick, A.M.2    Black, D.L.3
  • 46
    • 0030043709 scopus 로고    scopus 로고
    • Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: Implications for myotonic dystrophy
    • Timchenko LT, Timchenko NA, Caskey CT, Roberts R. 1996. Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: implications for myotonic dystrophy. Hum Mol Genet 5: 115-121.
    • (1996) Hum Mol Genet , vol.5 , pp. 115-121
    • Timchenko, L.T.1    Timchenko, N.A.2    Caskey, C.T.3    Roberts, R.4
  • 47
    • 1842529234 scopus 로고    scopus 로고
    • Overexpression of CUG triplet repeat-binding protein, CUGBP1, in mice inhibits myogenesis
    • Timchenko NA, Patel R, Iakova P, Cai ZJ, Quan L, Timchenko LT. 2004. Overexpression of CUG triplet repeat-binding protein, CUGBP1, in mice inhibits myogenesis. J Biol Chem 279: 13129-13139.
    • (2004) J Biol Chem , vol.279 , pp. 13129-13139
    • Timchenko, N.A.1    Patel, R.2    Iakova, P.3    Cai, Z.J.4    Quan, L.5    Timchenko, L.T.6
  • 48
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • Trapnell C, Pachter L, Salzberg SL. 2009. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25: 1105-1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 49
    • 57349138816 scopus 로고    scopus 로고
    • Posttranscriptional regulation of gene networks by GU-rich elements and CELF proteins
    • Vlasova IA, Bohjanen PR. 2008. Posttranscriptional regulation of gene networks by GU-rich elements and CELF proteins. RNA Biol 5: 201-207.
    • (2008) RNA Biol , vol.5 , pp. 201-207
    • Vlasova, I.A.1    Bohjanen, P.R.2
  • 52
    • 84896301208 scopus 로고    scopus 로고
    • Quality control: Is there quality control of localized mRNAs?
    • Walters R, Parker R. 2014. Quality control: is there quality control of localized mRNAs? J Cell Biol 204: 863-868.
    • (2014) J Cell Biol , vol.204 , pp. 863-868
    • Walters, R.1    Parker, R.2
  • 53
    • 70350719211 scopus 로고    scopus 로고
    • Engineering splicing factors with designed specificities
    • Wang Y, Cheong CG, Hall TM, Wang Z. 2009a. Engineering splicing factors with designed specificities. Nat Methods 6: 825-830.
    • (2009) Nat Methods , vol.6 , pp. 825-830
    • Wang, Y.1    Cheong, C.G.2    Hall, T.M.3    Wang, Z.4
  • 54
    • 67649840910 scopus 로고    scopus 로고
    • CLIP: Construction of cDNA libraries for high-throughput sequencing from RNAs cross-linked to proteins in vivo
    • Wang Z, Tollervey J, Briese M, Turner D, Ule J. 2009b. CLIP: construction of cDNA libraries for high-throughput sequencing from RNAs cross-linked to proteins in vivo. Methods 48: 287-293.
    • (2009) Methods , vol.48 , pp. 287-293
    • Wang, Z.1    Tollervey, J.2    Briese, M.3    Turner, D.4    Ule, J.5
  • 56
    • 77956108781 scopus 로고    scopus 로고
    • CUGBP1 over-expression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1
    • Ward AJ, Rimer M, Killian JM, Dowling JJ, Cooper TA. 2010. CUGBP1 over-expression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1. Hum Mol Genet 19: 3614-3622.
    • (2010) Hum Mol Genet , vol.19 , pp. 3614-3622
    • Ward, A.J.1    Rimer, M.2    Killian, J.M.3    Dowling, J.J.4    Cooper, T.A.5
  • 57
    • 36849035575 scopus 로고    scopus 로고
    • Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy
    • Wheeler TM, Lueck JD, Swanson MS, Dirksen RT, Thornton CA. 2007. Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy. J Clin Invest 117: 3952-3957.
    • (2007) J Clin Invest , vol.117 , pp. 3952-3957
    • Wheeler, T.M.1    Lueck, J.D.2    Swanson, M.S.3    Dirksen, R.T.4    Thornton, C.A.5
  • 58
    • 70349843229 scopus 로고    scopus 로고
    • Splice site strength-dependent activity and genetic buffering by poly-G runs
    • Xiao X, Wang Z, Jang M, Nutiu R, Wang ET, Burge CB. 2009. Splice site strength-dependent activity and genetic buffering by poly-G runs. Nat Struct Mol Biol 16: 1094-1100.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 1094-1100
    • Xiao, X.1    Wang, Z.2    Jang, M.3    Nutiu, R.4    Wang, E.T.5    Burge, C.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.