Systematic analysis of Cis-elements in unstable mRNAS demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cells

PLoS ONE

Volumn 5, Issue 6, 2010, Pages

  Lee, Jerome E ^a   Lee, Ju Youn ^b   Wilusz, Jeffrey ^a   Tian, Bin ^b   Wilusz, Carol J ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GU RICH ELEMENT BINDING FACTOR; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; HUR PROTEIN; MESSENGER RNA; MYOD1 PROTEIN; PROTEIN CUGBP1; PROTEIN MYOG; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CUGBP1 PROTEIN, MOUSE; ELAV-LIKE PROTEIN 1; MEMBRANE ANTIGEN;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL DIFFERENTIATION; CELL SPECIFICITY; CELL TRANSPORT; CELL TYPE; CONTROLLED STUDY; EMBRYONIC STEM CELL; IMMUNOPRECIPITATION; MICROARRAY ANALYSIS; MOUSE; MUSCLE CELL; NEUROMUSCULAR DISEASE; NONHUMAN; PLURIPOTENT STEM CELL; RNA STABILITY; TRANSCRIPTION REGULATION; ANIMAL; ANTIBODY SPECIFICITY; CHEMISTRY; DNA BASE COMPOSITION; GENETICS; HUMAN; KINETICS; METABOLISM; MYOBLAST; NUCLEOTIDE SEQUENCE; REGULATORY RNA SEQUENCE; SYSTEMS BIOLOGY;

3' UNTRANSLATED REGIONS; ANIMALS; ANTIGENS, SURFACE; BASE COMPOSITION; BASE SEQUENCE; HUMANS; KINETICS; MICE; MUSCLE CELLS; MYOBLASTS; ORGAN SPECIFICITY; REGULATORY SEQUENCES, RIBONUCLEIC ACID; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS; SYSTEMS BIOLOGY;

EID: 77955291454     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011201     Document Type: Article

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