메뉴 건너뛰기




Volumn 5, Issue 8, 2009, Pages

The CUGBP2 splicing factor regulates an ensemble of branchpoints from perimeter binding sites with implications for autoregulation

Author keywords

[No Author keywords available]

Indexed keywords

CUG BINDING PROTEIN 2; NUCLEIC ACID BINDING PROTEIN; UNCLASSIFIED DRUG; CUGBP2 PROTEIN, MOUSE; RNA BINDING PROTEIN; RNA PRECURSOR;

EID: 70149109214     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000595     Document Type: Article
Times cited : (27)

References (55)
  • 1
    • 0035252410 scopus 로고    scopus 로고
    • Alternative splicing: Increasing diversity in the proteomic world
    • DOI 10.1016/S0168-9525(00)02176-4, PII S0168952500021764
    • Graveley BR (2001) Alternative splicing: increasing diversity in the proteomic world. Trends Genet 17: 100-107. (Pubitemid 32140790)
    • (2001) Trends in Genetics , vol.17 , Issue.2 , pp. 100-107
    • Graveley, B.R.1
  • 2
  • 3
    • 0037062982 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing and proteome expansion in metazoans
    • DOI 10.1038/418236a
    • Maniatis T, Tasic B (2002) Alternative pre-mRNA splicing and proteome expansion in metazoans. Nature 418: 236-243. (Pubitemid 34773783)
    • (2002) Nature , vol.418 , Issue.6894 , pp. 236-243
    • Maniatis, T.1    Tasic, B.2
  • 4
    • 35548940665 scopus 로고    scopus 로고
    • Neuronal regulation of alternative pre-mRNA splicing
    • DOI 10.1038/nrn2237, PII NRN2237
    • Li Q, Lee JA, Black DL (2007) Neuronal regulation of alternative pre-mRNA splicing. Nat Rev Neurosci 8: 819-831. (Pubitemid 350006218)
    • (2007) Nature Reviews Neuroscience , vol.8 , Issue.11 , pp. 819-831
    • Li, Q.1    Lee, J.-A.2    Black, D.L.3
  • 5
    • 0032489021 scopus 로고    scopus 로고
    • Mechanical devices of the spliceosome: Motors, clocks, springs, and things
    • Staley JP, Guthrie C (1998) Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell 92: 315-326.
    • (1998) Cell , vol.92 , pp. 315-326
    • Staley, J.P.1    Guthrie, C.2
  • 6
    • 0345169036 scopus 로고    scopus 로고
    • Splicing double: Insights from the second spliceosome
    • Patel AA, Steitz JA (2003) Splicing double: insights from the second spliceosome. Nat Rev Mol Cell Biol 4: 960-970.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 960-970
    • Patel, A.A.1    Steitz, J.A.2
  • 7
    • 0013394889 scopus 로고    scopus 로고
    • Mechanisms of alternative pre-messenger RNA splicing
    • DOI 10.1146/annurev.biochem.72.121801.161720
    • Black DL (2003) Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem 72: 291-336. (Pubitemid 36930448)
    • (2003) Annual Review of Biochemistry , vol.72 , pp. 291-336
    • Black, D.L.1
  • 8
    • 0025098474 scopus 로고
    • Exon definition may facilitate splice site selection in RNAs with multiple exons
    • Robberson BL, Cote GJ, Berget SM (1990) Exon definition may facilitate splice site selection in RNAs with multiple exons. Mol Cell Biol 10: 84-94. (Pubitemid 20028960)
    • (1990) Molecular and Cellular Biology , vol.10 , Issue.1 , pp. 84-94
    • Robberson, B.L.1    Cote, G.J.2    Berget, S.M.3
  • 9
    • 0025760145 scopus 로고
    • Control of alternative splicing by the differential binding of U1 small nuclear ribonucleoprotein particle
    • Kuo HC, Nasim FH, Grabowski PJ (1991) Control of alternative splicing by the differential binding of U1 small nuclear ribonucleoprotein particle. Science 251: 1045-1050. (Pubitemid 21926196)
    • (1991) Science , vol.251 , Issue.4997 , pp. 1045-1050
    • Kuo, H.-C.1    Nasim, F.-U.H.2    Grabowski, P.J.3
  • 10
    • 0033835333 scopus 로고    scopus 로고
    • Sorting out the complexity of SR protein functions
    • Graveley BR (2000) Sorting out the complexity of SR protein functions. RNA 6: 1197-1211.
    • (2000) RNA , vol.6 , pp. 1197-1211
    • Graveley, B.R.1
  • 12
    • 0035146628 scopus 로고    scopus 로고
    • The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing
    • Ladd AN, Charlet N, Cooper TA (2001) The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing. Mol Cell Biol 21: 1285-1296.
    • (2001) Mol Cell Biol , vol.21 , pp. 1285-1296
    • Ladd, A.N.1    Charlet, N.2    Cooper, T.A.3
  • 13
    • 12844278103 scopus 로고    scopus 로고
    • Identification of putative new splicing targets for ETR-3 using sequences identified by systematic evolution of ligands by exponential enrichment
    • Faustino NA, Cooper TA (2005) Identification of putative new splicing targets for ETR-3 using sequences identified by systematic evolution of ligands by exponential enrichment. Mol Cell Biol 25: 879-887.
    • (2005) Mol Cell Biol , vol.25 , pp. 879-887
    • Faustino, N.A.1    Cooper, T.A.2
  • 14
    • 58149492467 scopus 로고    scopus 로고
    • A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
    • Kalsotra A, Xiao X, Ward AJ, Castle JC, Johnson JM, et al. (2008) A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Proc Natl Acad Sci U S A 105: 20333-20338.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20333-20338
    • Kalsotra, A.1    Xiao, X.2    Ward, A.J.3    Castle, J.C.4    Johnson, J.M.5
  • 15
    • 0029919450 scopus 로고    scopus 로고
    • Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy
    • Timchenko LT, Miller JW, Timchenko NA, DeVore DR, Datar KV, et al. (1996) Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy. Nucleic Acids Res 24: 4407-4414.
    • (1996) Nucleic Acids Res , vol.24 , pp. 4407-4414
    • Timchenko, L.T.1    Miller, J.W.2    Timchenko, N.A.3    DeVore, D.R.4    Datar, K.V.5
  • 16
    • 34948872683 scopus 로고    scopus 로고
    • Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy
    • DOI 10.1172/JCI32308
    • Wang GS, Kearney DL, De Biasi M, Taffet G, Cooper TA (2007) Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy. J Clin Invest 117: 2802-2811. (Pubitemid 47529611)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.10 , pp. 2802-2811
    • Wang, G.-S.1    Kearney, D.L.2    De Biasi, M.3    Taffet, G.4    Cooper, T.A.5
  • 17
    • 0036247201 scopus 로고    scopus 로고
    • Region-specific alternative splicing in the nervous system: Implications for regulation by the RNA-binding protein NAPOR
    • DOI 10.1017/S1355838202027036
    • Zhang W, Liu H, Han K, Grabowski PJ (2002) Region-specific alternative splicing in the nervous system: implications for regulation by the RNA-binding protein NAPOR. RNA 8: 671-685. (Pubitemid 34496585)
    • (2002) RNA , vol.8 , Issue.5 , pp. 671-685
    • Zhang, W.1    Liu, H.2    Han, K.3    Grabowski, P.J.4
  • 18
    • 0037450704 scopus 로고    scopus 로고
    • A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG
    • DOI 10.1093/emboj/cdg089
    • Jin Y, Suzuki H, Maegawa S, Endo H, Sugano S, et al. (2003) A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG. Embo J 22: 905-912. (Pubitemid 36227792)
    • (2003) EMBO Journal , vol.22 , Issue.4 , pp. 905-912
    • Jin, Y.1    Suzuki, H.2    Maegawa, S.3    Endo, H.4    Sugano, S.5    Hashimoto, K.6    Yasuda, K.7    Inoue, K.8
  • 20
    • 0033654522 scopus 로고    scopus 로고
    • [1] Probing RNA structure and RNA-ligand complexes with chemical probes
    • Brunel C, Romby P (2000) Probing RNA structure and RNA-ligand complexes with chemical probes. Methods Enzymol 318: 3-21. (Pubitemid 30421636)
    • (2000) Methods in Enzymology , vol.318 , pp. 3-21
    • Brunel, C.1    Romby, P.2
  • 21
    • 20444443019 scopus 로고    scopus 로고
    • Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development
    • Ladd AN, Stenberg MG, Swanson MS, Cooper TA (2005) Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development. Dev Dyn 233: 783-793.
    • (2005) Dev Dyn , vol.233 , pp. 783-793
    • Ladd, A.N.1    Stenberg, M.G.2    Swanson, M.S.3    Cooper, T.A.4
  • 22
    • 34249696543 scopus 로고    scopus 로고
    • Discovery and analysis of evolutionarily conserved intronic splicing regulatory elements
    • doi: 10.1371/journal.pgen.0030085
    • Yeo GW, Van Nostrand EL, Liang TY (2007) Discovery and analysis of evolutionarily conserved intronic splicing regulatory elements. PLoS Genet 3: e85. doi: 10.1371/journal.pgen.0030085.
    • (2007) PLoS Genet , vol.3
    • Yeo, G.W.1    Van Nostrand, E.L.2    Liang, T.Y.3
  • 23
    • 42449129086 scopus 로고    scopus 로고
    • Human branch point consensus sequence is yUnAy
    • DOI 10.1093/nar/gkn073
    • Gao K, Masuda A, Matsuura T, Ohno K (2008) Human branch point consensus sequence is yUnAy. Nucleic Acids Res 36: 2257-2267. (Pubitemid 351575093)
    • (2008) Nucleic Acids Research , vol.36 , Issue.7 , pp. 2257-2267
    • Gao, K.1    Masuda, A.2    Matsuura, T.3    Ohno, K.4
  • 25
    • 0036193474 scopus 로고    scopus 로고
    • Regulation of alternative splicing of alpha-actinin transcript by Bruno-like proteins
    • DOI 10.1046/j.1356-9597.2001.00506.x
    • Suzuki H, Jin Y, Otani H, Yasuda K, Inoue K (2002) Regulation of alternative splicing of alpha-actinin transcript by Bruno-like proteins. Genes Cells 7: 133-141. (Pubitemid 34213358)
    • (2002) Genes to Cells , vol.7 , Issue.2 , pp. 133-141
    • Suzuki, H.1    Jin, Y.2    Otani, H.3    Yasuda, K.4    Inoue, K.5
  • 26
    • 0028952455 scopus 로고
    • Cooperation of 5′ and 3′ processing sites as well as intron and exon sequences in calcitonin exon recognition
    • Zandberg H, Moen TC, Baas PD (1995) Cooperation of 5′ and 3′ processing sites as well as intron and exon sequences in calcitonin exon recognition. Nucleic Acids Res 23: 248-255.
    • (1995) Nucleic Acids Res , vol.23 , pp. 248-255
    • Zandberg, H.1    Moen, T.C.2    Baas, P.D.3
  • 27
    • 0024438353 scopus 로고
    • Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice receptor
    • DOI 10.1038/341076a0
    • Emeson RB, Hedjran F, Yeakley JM, Guise JW, Rosenfeld MG (1989) Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor. Nature 341: 76-80. (Pubitemid 19220663)
    • (1989) Nature , vol.341 , Issue.6237 , pp. 76-80
    • Emeson, R.B.1    Hedjran, F.2    Yeakley, J.M.3    Guise, J.W.4    Rosenfeld, M.G.5
  • 28
    • 0026045938 scopus 로고
    • Deregulation of alternative processing of Calcitonin/ CGRP-I pre-mRNA by a single point mutation
    • Adema GJ, Baas PD (1991) Deregulation of alternative processing of Calcitonin/ CGRP-I pre-mRNA by a single point mutation. Biochem Biophys Res Commun 178: 985-992.
    • (1991) Biochem Biophys Res Commun , vol.178 , pp. 985-992
    • Adema, G.J.1    Baas, P.D.2
  • 29
    • 11144328200 scopus 로고    scopus 로고
    • A novel intronic cis element, ISE/ISS-3, regulates rat fibroblast growth factor receptor 2 splicing through activation of an upstream exon and repression of a downstream exon containing a noncanonical branch point sequence
    • Hovhannisyan RH, Carstens RP (2005) A novel intronic cis element, ISE/ISS-3, regulates rat fibroblast growth factor receptor 2 splicing through activation of an upstream exon and repression of a downstream exon containing a noncanonical branch point sequence. Mol Cell Biol 25: 250-263.
    • (2005) Mol Cell Biol , vol.25 , pp. 250-263
    • Hovhannisyan, R.H.1    Carstens, R.P.2
  • 30
    • 0024390066 scopus 로고
    • Branch point selection in alternative splicing of tropomyosin pre-mRNAs
    • Helfman DM, Ricci WM (1989) Branch point selection in alternative splicing of tropomyosin pre-mRNAs. Nucleic Acids Res 17: 5633-5650.
    • (1989) Nucleic Acids Res , vol.17 , pp. 5633-5650
    • Helfman, D.M.1    Ricci, W.M.2
  • 31
    • 0023877583 scopus 로고
    • Unusual branch point selection in processing of human growth hormone pre-mRNA
    • Hartmuth K, Barta A (1988) Unusual branch point selection in processing of human growth hormone pre-mRNA. Mol Cell Biol 8: 2011-2020. (Pubitemid 18123093)
    • (1988) Molecular and Cellular Biology , vol.8 , Issue.5 , pp. 2011-2020
    • Hartmuth, K.1    Barta, A.2
  • 32
    • 0028209981 scopus 로고
    • Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly
    • Staknis D, Reed R (1994) Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly. Mol Cell Biol 14: 2994-3005. (Pubitemid 24132713)
    • (1994) Molecular and Cellular Biology , vol.14 , Issue.5 , pp. 2994-3005
    • Staknis, D.1    Reed, R.2
  • 33
    • 0029894931 scopus 로고    scopus 로고
    • Identification of proteins that interact with exon sequences, splice sites, and the branchpoint sequence during each stage of spliceosome assembly
    • Chiara MD, Gozani O, Bennett M, Champion-Arnaud P, Palandjian L, et al. (1996) Identification of proteins that interact with exon sequences, splice sites, and the branchpoint sequence during each stage of spliceosome assembly. Mol Cell Biol 16: 3317-3326. (Pubitemid 26199851)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.7 , pp. 3317-3326
    • Chiara, M.D.1    Gozani, O.R.2    Bennett, M.3    Champion-Arnaud, P.4    Palandjian, L.5    Reed, R.6
  • 34
    • 0030595187 scopus 로고    scopus 로고
    • 65 RS region with pre-mRNA of branch point and promotion base pairing with U2 snRNA
    • Valcarcel J, Gaur RK, Singh R, Green MR (1996) Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA [corrected]. Science 273: 1706-1709. (Pubitemid 26317785)
    • (1996) Science , vol.273 , Issue.5282 , pp. 1706-1709
    • Valcarcel, J.1    Gaur, R.K.2    Singh, R.3    Green, M.R.4
  • 35
    • 8644268780 scopus 로고    scopus 로고
    • A pathway of sequential Arginine-Serine-Rich Domain-Splicing signal interactions during mammalian spliceosome assembly
    • DOI 10.1016/j.molcel.2004.10.021, PII S1097276504006379
    • Shen H, Green MR (2004) A pathway of sequential arginine-serine-rich domainsplicing signal interactions during mammalian spliceosome assembly. Mol Cell 16: 363-373. (Pubitemid 39504791)
    • (2004) Molecular Cell , vol.16 , Issue.3 , pp. 363-373
    • Shen, H.1    Green, M.R.2
  • 36
    • 1242316952 scopus 로고    scopus 로고
    • Arginine-Serine-Rich Domains Bound at Splicing Enhancers Contact the Branchpoint to Promote Prespliceosome Assembly
    • DOI 10.1016/S1097-2765(04)00025-5
    • Shen H, Kan JL, Green MR (2004) Arginine-serine-rich domains bound at splicing enhancers contact the branchpoint to promote prespliceosome assembly. Mol Cell 13: 367-376. (Pubitemid 38229809)
    • (2004) Molecular Cell , vol.13 , Issue.3 , pp. 367-376
    • Shen, H.1    Kan, J.L.C.2    Green, M.R.3
  • 37
    • 0030911051 scopus 로고    scopus 로고
    • Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals
    • DOI 10.1016/S0092-8674(00)80221-4
    • Abovich N, Rosbash M (1997) Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals. Cell 89: 403-412. (Pubitemid 27220885)
    • (1997) Cell , vol.89 , Issue.3 , pp. 403-412
    • Abovich, N.1    Rosbash, M.2
  • 39
    • 0031878108 scopus 로고    scopus 로고
    • A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site
    • Gozani O, Potashkin J, Reed R (1998) A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site. Mol Cell Biol 18: 4752-4760. (Pubitemid 28343060)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.8 , pp. 4752-4760
    • Gozani, O.1    Potashkin, J.2    Reed, R.3
  • 40
    • 0032521186 scopus 로고    scopus 로고
    • A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition
    • Berglund JA, Abovich N, Rosbash M (1998) A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition. Genes Dev 12: 858-867. (Pubitemid 28150886)
    • (1998) Genes and Development , vol.12 , Issue.6 , pp. 858-867
    • Berglund, J.A.1    Abovich, N.2    Rosbash, M.3
  • 41
    • 60749134015 scopus 로고    scopus 로고
    • Assembly of ribosomes and spliceosomes: Complex ribonucleoprotein machines
    • Staley JP, Woolford JL Jr (2009) Assembly of ribosomes and spliceosomes: complex ribonucleoprotein machines. Curr Opin Cell Biol 21: 109-118.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 109-118
    • Staley, J.P.1    Woolford Jr., J.L.2
  • 43
    • 0033134777 scopus 로고    scopus 로고
    • Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA
    • Ding J, Hayashi MK, Zhang Y, Manche L, Krainer AR, et al. (1999) Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with singlestranded telomeric DNA. Genes Dev 13: 1102-1115. (Pubitemid 29233142)
    • (1999) Genes and Development , vol.13 , Issue.9 , pp. 1102-1115
    • Ding, J.1    Hayashi, M.K.2    Zhang, Y.3    Manche, L.4    Krainer, A.R.5    Xu, R.-M.6
  • 44
    • 33745499067 scopus 로고    scopus 로고
    • Structural Basis for Polypyrimidine Tract Recognition by the Essential Pre-mRNA Splicing Factor U2AF65
    • DOI 10.1016/j.molcel.2006.05.025, PII S1097276506003406
    • Sickmier EA, Frato KE, Shen H, Paranawithana SR, Green MR, et al. (2006) Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65. Mol Cell 23: 49-59. (Pubitemid 43963446)
    • (2006) Molecular Cell , vol.23 , Issue.1 , pp. 49-59
    • Sickmier, E.A.1    Frato, K.E.2    Shen, H.3    Paranawithana, S.R.4    Green, M.R.5    Kielkopf, C.L.6
  • 45
    • 0346124413 scopus 로고    scopus 로고
    • Autoregulation of Polypyrimidine Tract Binding Protein by Alternative Splicing Leading to Nonsense-Mediated Decay
    • DOI 10.1016/S1097-2765(03)00502-1
    • Wollerton MC, Gooding C, Wagner EJ, Garcia-Blanco MA, Smith CW (2004) Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay. Mol Cell 13: 91-100. (Pubitemid 38117118)
    • (2004) Molecular Cell , vol.13 , Issue.1 , pp. 91-100
    • Wollerton, M.C.1    Gooding, C.2    Wagner, E.J.3    Garcia-Blanco, M.A.4    Smith, C.W.J.5
  • 46
    • 32044467372 scopus 로고    scopus 로고
    • Fox-2 mediates epithelial cellspecific fibroblast growth factor receptor 2 exon choice
    • Baraniak AP, Chen JR, Garcia-Blanco MA (2006) Fox-2 mediates epithelial cellspecific fibroblast growth factor receptor 2 exon choice. Mol Cell Biol 26: 1209-1222.
    • (2006) Mol Cell Biol , vol.26 , pp. 1209-1222
    • Baraniak, A.P.1    Chen, J.R.2    Garcia-Blanco, M.A.3
  • 47
    • 18444362088 scopus 로고    scopus 로고
    • Nova autoregulation reveals dual functions in neuronal splicing
    • DOI 10.1038/sj.emboj.7600630
    • Dredge BK, Stefani G, Engelhard CC, Darnell RB (2005) Nova autoregulation reveals dual functions in neuronal splicing. Embo J 24: 1608-1620. (Pubitemid 40646450)
    • (2005) EMBO Journal , vol.24 , Issue.8 , pp. 1608-1620
    • Dredge, B.K.1    Stefani, G.2    Engelhard, C.C.3    Darnell, R.B.4
  • 49
    • 20444368053 scopus 로고    scopus 로고
    • Neuronal proteins custom designed by alternative splicing
    • Lipscombe D (2005) Neuronal proteins custom designed by alternative splicing. Curr Opin Neurobiol 15: 358-363.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 358-363
    • Lipscombe, D.1
  • 50
    • 0038382977 scopus 로고    scopus 로고
    • Nova regulates GABA(A) receptor gamma2 alternative splicing via a distal downstream UCAU-rich intronic splicing enhancer
    • Dredge BK, Darnell RB (2003) Nova regulates GABA(A) receptor gamma2 alternative splicing via a distal downstream UCAU-rich intronic splicing enhancer. Mol Cell Biol 23: 4687-4700.
    • (2003) Mol Cell Biol , vol.23 , pp. 4687-4700
    • Dredge, B.K.1    Darnell, R.B.2
  • 51
    • 0036203307 scopus 로고    scopus 로고
    • Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing
    • DOI 10.1016/S1097-2765(02)00479-3
    • Charlet BN, Logan P, Singh G, Cooper TA (2002) Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing. Mol Cell 9: 649-658. (Pubitemid 34273794)
    • (2002) Molecular Cell , vol.9 , Issue.3 , pp. 649-658
    • Charlet-B, N.1    Logan, P.2    Singh, G.3    Cooper, T.A.4
  • 52
    • 0030832044 scopus 로고    scopus 로고
    • A complex intronic splicing enhancer from the csrc pre-mRNA activates inclusion of a heterologous exon
    • Modafferi EF, Black DL (1997) A complex intronic splicing enhancer from the csrc pre-mRNA activates inclusion of a heterologous exon. Mol Cell Biol 17: 6537-6545.
    • (1997) Mol Cell Biol , vol.17 , pp. 6537-6545
    • Modafferi, E.F.1    Black, D.L.2
  • 53
    • 33846994060 scopus 로고    scopus 로고
    • Exon silencing by UAGG motifs in response to neuronal excitation
    • doi:10.1371/journal.pbio.0050036
    • An P, Grabowski PJ (2007) Exon silencing by UAGG motifs in response to neuronal excitation. PLoS Biol 5: e36. doi:10.1371/journal.pbio.0050036.
    • (2007) PLoS Biol , vol.5
    • An, P.1    Grabowski, P.J.2
  • 54
    • 0030777180 scopus 로고    scopus 로고
    • A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: Evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart
    • Ashiya M, Grabowski PJ (1997) A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart. RNA 3: 996-1015. (Pubitemid 27371735)
    • (1997) RNA , vol.3 , Issue.9 , pp. 996-1015
    • Ashiya, M.1    Grabowski, P.J.2
  • 55
    • 0027090479 scopus 로고
    • U1 snRNP targets an essential splicing factor, U2AF65, to the 3′ splice site by a network of interactions spanning the exon
    • Hoffman BE, Grabowski PJ (1992) U1 snRNP targets an essential splicing factor, U2AF65, to the 3′ splice site by a network of interactions spanning the exon. Genes Dev 6: 2554-2568.
    • (1992) Genes Dev , vol.6 , pp. 2554-2568
    • Hoffman, B.E.1    Grabowski, P.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.