MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development

Genes and Development

Volumn 24, Issue 7, 2010, Pages 653-658

  Kalsotra, Auinash ^a   Wang, Kun ^b   Li, Pei Feng ^b   Cooper, Thomas A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b INSTITUTE OF ZOOLOGY   (China)

Author keywords

Alternative splicing networks; CELF proteins; Heart development; MicroRNA

Indexed keywords

BINDING PROTEIN; CUGBP1 PROTEIN; CUGBP2 PROTEIN; DICER; ETR 3 LIKE FACTOR; MICRORNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CUGBP1 PROTEIN, MOUSE; DEAD BOX PROTEIN; DICER1 PROTEIN, MOUSE; MIRN23B MICRORNA, MOUSE; RIBONUCLEASE; RNA BINDING PROTEIN;

ADULT ANIMAL; ALTERNATIVE RNA SPLICING; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE DELETION; GENE EXPRESSION; HEART DEVELOPMENT; HEART MUSCLE; KNOCKOUT GENE; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; UPREGULATION; ANIMAL; CELL LINE; DRUG ANTAGONISM; GENE SILENCING; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEART; METABOLISM; PHYSIOLOGY;

VERTEBRATA;

ALTERNATIVE SPLICING; ANIMALS; CELL LINE; DEAD-BOX RNA HELICASES; DOWN-REGULATION; ENDORIBONUCLEASES; GENE KNOCKDOWN TECHNIQUES; HEART; MICE; MICRORNAS; RNA-BINDING PROTEINS; UP-REGULATION;

EID: 77950513681     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1894310     Document Type: Article

References (28)

1. Baek D, Villen J, Shin C, Camargo FD, Gygi SP, Bartel DP. 2008. The impact of microRNAs on protein output. Nature 455: 64-71.
2. Bartel DP. 2009. MicroRNAs: Target recognition and regulatory functions. Cell 136: 215-233.
3. Birchler JA, Kavi HH. 2008. Molecular biology. Slicing and dicing for small RNAs. Science 320: 1023-1024. (Pubitemid 351934163)
4. Blencowe BJ. 2006. Alternative splicing: New insights from global analyses. Cell 126: 37-47.
5. Boutz PL, Chawla G, Stoilov P, Black DL. 2007. MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. Genes & Dev 21: 71-84. (Pubitemid 46089709)
6. Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, et al. 2004. PKC- regulates cardiac contractility and propensity toward heart failure. Nat Med 10:248-254.
7. Castle JC, Zhang C, Shah JK, Kulkami AV, Kalsotra A, Cooper TA, Johnson JM. 2008. Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines. Nat Genet 40: 1416-1425.
8. Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, et al. 2008. Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci 105: 2111-2116. (Pubitemid 351439473)
9. Claycomb WC, Lanson NA Jr, Stallworth BS, Egeland DB, Delcarpio JB, Bahinski A, Izzo NJ Jr. 1998. HL-I cells: A cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc Natl Acad Sci 95: 2979-2984. (Pubitemid 28135840)
10. Cooper TA, Wan L, Dreyfuss G. 2009. RNA and disease. Cell 136: 777793.
11. da Costa Martins PA, Bourajjaj M, Gladka M, Kortland M, van Oort RJ, Pinto YM, Molkentin JD, De Windt LJ. 2008. Conditional dicer gene deletion in the postnatal myocardium provokes spontaneous cardiac remodeling. circulation 118: 1567-1576.
12. Ji Z, Lee JY, Pan Z, Jiang B, Tian B. 2009. Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development. Proc Natl Acad Sci 106: 70287033.
13. Kalsotra A, Xiao X, Ward AJ, Castle JC, Johnson JM, Burge CB, Cooper TA. 2008. A postnatal switch of CELF and MBNL proteins reprograme alternative splicing in the developing heart. Proc Natl Acad Sci 105: 20333-20338.
14. Kim VN. 2005. MicroRNA biogenesis: Coordinated cropping and dicing. Nat Rev Mol Cell Biol 6: 376-385.
15. Kuyumcu-Martinez NM, Wang GS, Cooper TA. 2007. Increased steadystate levels of CUGBPl in myotonic dystrophy 1 are due to PKCmediated hyperphosphorylation. Mol Cell 28: 68-78.
16. Lin Z, Murtaza I, Wang K, Jiao J, Gao J, Li PF. 2009. miR-23a functions downstream of NFATcS to regulate cardiac hypertrophy. Proc Natl Acad Sci 106: 12103-12108.
17. Makeyev EV, Zhang J, Carrasco MA, Maniatis T. 2007. The microRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell 27: 435-448. (Pubitemid 47126944)
18. Olson EN. 2006. Gene regulatory networks in the evolution and development of the heart. Science 313: 1922-1927. (Pubitemid 44497993)
19. Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ. 2008. Deep surveying of alternative splicing complexity in the human transcriptome by highthroughput sequencing. Nat Genet 40: 1413-1415.
20. Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB. 2008. Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites. Science 320: 1643-1647. (Pubitemid 351931255)
21. Sano M, Abdellatif M, Oh H, Xie M, Bagella L, Giordano A, Michael LH, DeMayo FJ, Schneider MD. 2002. Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy. Net Med 8: 1310-1317. (Pubitemid 35373565)
22. Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, Rajewsky N. 2008. Widespread changes in protein synthesis induced by microRNAs. Nature 455: 58-63.
23. SohalDS,NghiemM,CrackowerMA,WittSA,KimballTR,TymitzKM,PenningerJM, MolkentinJD.2001. Temporallyregulatedandtissuespecificgenemanipulationsintheadultandembryo nicheartusingatamoxifen-inducibleCreprotein.CircRes89:20-25.(Pubitemid34135487)
24. van Rooij E, Sutherland LB, Qi X, Richardson JA, Hill J, Olson EN. 2007. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 316: 575-579. (Pubitemid 46683138)
25. Wang ET, Sandberg R, Luo S, Khrebtukova I, Zhang L, Mayr C, Kingsmore SF, Schroth GP, Burge CB. 2008. Alternative isoform regulation in human tissue transcriptomes. Nature 456: 470-476. (Pubitemid 352759009)
26. Xu X, Yang D, Ding JH, Wang W, Chu PH, Dalton ND, Wang HY, Bermingham JR Jr, Ye Z, Liu F, et al. 2005. ASF/SF2-regulated Ca MKIIδ alternative splicing temporally reprograme excitation-contraction coupling in cardiac muscle. Cell 120: 59-72.
27. Yi R, O'Carroll D, Pasolli HA, Zhang Z, Dietrich FS, Tarakhovsky A, Fuchs E. 2006. Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet 38: 356-362. (Pubitemid 43315760)
28. Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D. 2007. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 129: 303-317. (Pubitemid 46574975)