TLR2 deficiency attenuates skeletal muscle atrophy in mice

Biochemical and Biophysical Research Communications

Volumn 459, Issue 3, 2015, Pages 534-540

  Kim, Dae Sung ^a   Cha, Hye Na ^a   Jo, Hye Jun ^a   Song, In Hwan ^a   Baek, Suk Hwan ^a   Dan, Jin Myoung ^b   Kim, Yong Woon ^a   Kim, Jong Yeon ^a   Lee, In Kyu ^c   Seo, Jae Sung ^a   Park, So Young ^a  

^a Yeungnam University College of Medicine   (South Korea)

^b Department of Orthopedic Surgery   (South Korea)

^c Kyungpook National University   (South Korea)

Author keywords

Atrophy; Cardiotoxin; Immobilization; Oxidative stress; Skeletal muscle; TLR2

Indexed keywords

COBROTOXIN; CYTOKINE; MESSENGER RNA; TLR2 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 2;

ANIMAL; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; IMMOBILIZATION; KNOCKOUT MOUSE; MALE; METABOLISM; MOUSE; MUSCLE ATROPHY; OXIDATIVE STRESS; PATHOLOGY; PHOSPHORYLATION; PROTEIN CARBONYLATION; PROTEIN DEGRADATION; SKELETAL MUSCLE; UBIQUITINATION;

ANIMALS; COBRA CARDIOTOXIN PROTEINS; CYTOKINES; DISEASE MODELS, ANIMAL; IMMOBILIZATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SKELETAL; MUSCULAR ATROPHY; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN CARBONYLATION; PROTEOLYSIS; RNA, MESSENGER; TOLL-LIKE RECEPTOR 2; UBIQUITINATION;

EID: 84931435681     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.02.144     Document Type: Article

References (44)

1. O. Boonyarom, and K. Inui Atrophy and hypertrophy of skeletal muscles: structural and functional aspects Acta Physiol. (Oxf) 188 2006 77 89
2. R.W. Jackman, and S.C. Kandarian The molecular basis of skeletal muscle atrophy Am. J. Physiol., Cell. Physiol. 287 2004 C834 C843
3. P. Zhang, X. Chen, and M. Fan Signaling mechanisms involved in disuse muscle atrophy Med. Hypotheses 69 2007 310 321
4. S.J. Meng, and L.J. Yu Oxidative stress, molecular inflammation and sarcopenia Int. J. Mol. Sci. 11 2010 1509 1526
5. R. Ringseis, J. Keller, and K. Eder Mechanisms underlying the anti-wasting effect of L-carnitine supplementation under pathologic conditions: evidence from experimental and clinical studies Eur. J. Nutr. 52 2013 1421 1442
6. S.K. Bae, H.N. Cha, T.J. Ju, Y.W. Kim, H.S. Kim, Y.D. Kim, J.M. Dan, J.Y. Kim, S.D. Kim, and S.Y. Park Deficiency of inducible nitric oxide synthase attenuates immobilization-induced skeletal muscle atrophy in mice J. Appl. Physiol. 113 2012 114 123
7. C.H. Park, T.J. Ju, Y.W. Kim, J.M. Dan, J.Y. Kim, Y.D. Kim, J.S. Seo, and S.Y. Park Hemin, heme oxygenase-1 inducer, attenuates immobilization-induced skeletal muscle atrophy in mice Life Sci. 92 2013 740 746
8. J.M. Lawler, M. Kunst, J.M. Hord, Y. Lee, K. Joshi, R.E. Botchlett, A. Ramirez, and D.A. Martinez EUK-134 ameliorates nNOSmu translocation and skeletal muscle fiber atrophy during short-term mechanical unloading Am. J. Physiol. Regul. Integr. Comp. Physiol. 306 2014 R470 R482
9. Z.L. Chang Important aspects of Toll-like receptors, ligands and their signaling pathways Inflamm. Res. 59 2010 791 808
10. A. Poltorak, X. He, I. Smirnova, M.Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, M. Freudenberg, P. Ricciardi-Castagnoli, B. Layton, and B. Beutler Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene Science 282 1998 2085 2088
11. C.H. Lang, C. Silvis, N. Deshpande, G. Nystrom, and R.A. Frost Endotoxin stimulates in vivo expression of inflammatory cytokines tumor necrosis factor alpha, interleukin-1beta, -6, and high-mobility-group protein-1 in skeletal muscle Shock 19 2003 538 546
12. M. Nishimura, and S. Naito Tissue-specific mRNA expression profiles of human toll-like receptors and related genes Biol. Pharm. Bull. 28 2005 886 892
13. L. Schaefer, A. Babelova, E. Kiss, H.J. Hausser, M. Baliova, M. Krzyzankova, G. Marsche, M.F. Young, D. Mihalik, M. Gotte, E. Malle, R.M. Schaefer, and H.J. Grone The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages J. Clin. Invest 115 2005 2223 2233
14. E. Latorre, C. Mendoza, E. Layunta, A.I. Alcalde, and J.E. Mesonero TLR2, TLR3, and TLR4 activation specifically alters the oxidative status of intestinal epithelial cells Cell. Stress Chaperones 19 2014 289 293
15. J.H. Boyd, S. Mathur, Y. Wang, R.M. Bateman, and K.R. Walley Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response Cardiovasc Res. 72 2006 384 393
16. A. Kadl, P.R. Sharma, W. Chen, R. Agrawal, A.K. Meher, S. Rudraiah, N. Grubbs, R. Sharma, and N. Leitinger Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2 Free Radic. Biol. Med. 51 2011 1903 1909
17. H. Lin, X.B. Liu, J.J. Yu, F. Hua, and Z.W. Hu Antioxidant N-acetylcysteine attenuates hepatocarcinogenesis by inhibiting ROS/ER stress in TLR2 deficient mouse PLoS One 8 2013 e74130
18. A.M. Caricilli, P.H. Nascimento, J.R. Pauli, D.M. Tsukumo, L.A. Velloso, J.B. Carvalheira, and M.J. Saad Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet J. Endocrinol. 199 2008 399 406
19. J.J. Senn Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes J. Biol. Chem. 281 2006 26865 26875
20. A.Z. Caron, G. Drouin, J. Desrosiers, F. Trensz, and G. Grenier A novel hindlimb immobilization procedure for studying skeletal muscle atrophy and recovery in mouse J. Appl. Physiol. 106 2009 2049 2059
21. L. Combaret, D. Dardevet, D. Bechet, D. Taillandier, L. Mosoni, and D. Attaix Skeletal muscle proteolysis in aging Curr. Opin. Clin. Nutr. Metab. Care 12 2009 37 41
22. P.O. Hasselgren, C. Wray, and J. Mammen Molecular regulation of muscle cachexia: it may be more than the proteasome Biochem. Biophys. Res. Commun. 290 2002 1 10
23. M.J. Tisdale The ubiquitin-proteasome pathway as a therapeutic target for muscle wasting J. Support Oncol. 3 2005 209 217
24. H.A. Franch, and S.R. Price Molecular signaling pathways regulating muscle proteolysis during atrophy Curr. Opin. Clin. Nutr. Metab. Care 8 2005 271 275
25. D.J. Glass Signaling pathways perturbing muscle mass Curr. Opin. Clin. Nutr. Metab. Care 13 2010 225 229
26. S.C. Bodine, E. Latres, S. Baumhueter, V.K. Lai, L. Nunez, B.A. Clarke, W.T. Poueymirou, F.J. Panaro, E. Na, K. Dharmarajan, Z.Q. Pan, D.M. Valenzuela, T.M. DeChiara, T.N. Stitt, G.D. Yancopoulos, and D.J. Glass Identification of ubiquitin ligases required for skeletal muscle atrophy Science 294 2001 1704 1708
27. M. Sandri, C. Sandri, A. Gilbert, C. Skurk, E. Calabria, A. Picard, K. Walsh, S. Schiaffino, S.H. Lecker, and A.L. Goldberg Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy Cell 117 2004 399 412
28. D.S. Waddell, L.M. Baehr, J. van den Brandt, S.A. Johnsen, H.M. Reichardt, J.D. Furlow, and S.C. Bodine The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene Am. J. Physiol. Endocrinol. Metab. 295 2008 E785 E797
29. A.K. Fjallstrom, K. Evertsson, M. Norrby, and S. Tagerud Forkhead box O1 and muscle RING finger 1 protein expression in atrophic and hypertrophic denervated mouse skeletal muscle J. Mol. Signal 9 2014 9
30. D. Lee, and A.L. Goldberg SIRT1 protein, by blocking the activities of transcription factors FoxO1 and FoxO3, inhibits muscle atrophy and promotes muscle growth J. Biol. Chem. 288 2013 30515 30526
31. Y. Kamei, S. Miura, M. Suzuki, Y. Kai, J. Mizukami, T. Taniguchi, K. Mochida, T. Hata, J. Matsuda, H. Aburatani, I. Nishino, and O. Ezaki Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control J. Biol. Chem. 279 2004 41114 41123
32. F.L. Muller, W. Song, Y.C. Jang, Y. Liu, M. Sabia, A. Richardson, and H. Van Remmen Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production Am. J. Physiol. Regul. Integr. Comp. Physiol. 293 2007 R1159 R1168
33. M. Okutsu, J.A. Call, V.A. Lira, M. Zhang, J.A. Donet, B.A. French, K.S. Martin, S.M. Peirce-Cottler, C.M. Rembold, B.H. Annex, and Z. Yan Extracellular superoxide dismutase ameliorates skeletal muscle abnormalities, cachexia, and exercise intolerance in mice with congestive heart failure Circ. Heart Fail 7 2014 519 530
34. E. Barreiro, and S.N. Hussain Protein carbonylation in skeletal muscles: impact on function Antioxid. Redox Signal 12 2010 417 429
35. K. Min, A.J. Smuder, O.S. Kwon, A.N. Kavazis, H.H. Szeto, and S.K. Powers Mitochondrial-targeted antioxidants protect skeletal muscle against immobilization-induced muscle atrophy J. Appl. Physiol. 111 2011 1459 1466
36. E.E. Talbert, A.J. Smuder, K. Min, O.S. Kwon, H.H. Szeto, and S.K. Powers Immobilization-induced activation of key proteolytic systems in skeletal muscles is prevented by a mitochondria-targeted antioxidant J. Appl. Physiol. (1985) 115 2013 529 538
37. A.Z. Caron, S. Haroun, E. Leblanc, F. Trensz, C. Guindi, A. Amrani, and G. Grenier The proteasome inhibitor MG132 reduces immobilization-induced skeletal muscle atrophy in mice BMC Musculoskelet. Disord. 12 2011 185
38. J.E. Davis, N.K. Gabler, J. Walker-Daniels, and M.E. Spurlock The c-Jun N-terminal kinase mediates the induction of oxidative stress and insulin resistance by palmitate and toll-like receptor 2 and 4 ligands in 3T3-L1 adipocytes Horm. Metab. Res. 41 2009 523 530
39. J.E. Fletcher, and M.S. Jiang Possible mechanisms of action of cobra snake venom cardiotoxins and bee venom melittin Toxicon 31 1993 669 695
40. B.C. Yaden, Y.X. Wang, J.M. Wilson, A.E. Culver, A. Milner, A. Datta-Mannan, P. Shetler, J.E. Croy, G. Dai, and V. Krishnan Inhibition of activin A ameliorates skeletal muscle injury and rescues contractile properties by inducing efficient remodeling in female mice Am. J. Pathol. 184 2014 1152 1166
41. C.A. Goodman, M.H. Miu, J.W. Frey, D.M. Mabrey, H.C. Lincoln, Y. Ge, J. Chen, and T.A. Hornberger A phosphatidylinositol 3-kinase/protein kinase B-independent activation of mammalian target of rapamycin signaling is sufficient to induce skeletal muscle hypertrophy Mol. Biol. Cell. 21 2010 3258 3268
42. M. Ohanna, A.K. Sobering, T. Lapointe, L. Lorenzo, C. Praud, E. Petroulakis, N. Sonenberg, P.A. Kelly, A. Sotiropoulos, and M. Pende Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control Nat. Cell. Biol. 7 2005 286 294
43. J.B. Li, and A.L. Goldberg Effects of food deprivation on protein synthesis and degradation in rat skeletal muscles Am. J. Phys. 231 1976 441 448
44. H.M. Argadine, N.J. Hellyer, C.B. Mantilla, W.Z. Zhan, and G.C. Sieck The effect of denervation on protein synthesis and degradation in adult rat diaphragm muscle J. Appl. Physiol. (1985) 107 2009 438 444