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Volumn 184, Issue 4, 2014, Pages 1152-1166

Inhibition of activin a ameliorates skeletal muscle injury and rescues contractile properties by inducing efficient remodeling in female mice

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; ATROGIN 1; CARDIOTOXIN; GROWTH DIFFERENTIATION FACTOR 15; IMMUNOGLOBULIN G1; INHIBIN A; INTERLEUKIN 17; INTERLEUKIN 6; LYMPHOTOXIN; MESSENGER RNA; TUMOR NECROSIS FACTOR; ACTIVIN; TRANSCRIPTOME;

EID: 84897903860     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.12.029     Document Type: Article
Times cited : (25)

References (67)
  • 1
    • 84866742560 scopus 로고    scopus 로고
    • TGFbeta signalling in context
    • J. Massague TGFbeta signalling in context Nat Rev Mol Cell Biol 13 2012 616 630
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 616-630
    • Massague, J.1
  • 5
    • 33744720767 scopus 로고    scopus 로고
    • Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy
    • S.A. Parsons, D.P. Millay, M.A. Sargent, E.M. McNally, and J.D. Molkentin Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy Am J Pathol 168 2006 1975 1985
    • (2006) Am J Pathol , vol.168 , pp. 1975-1985
    • Parsons, S.A.1    Millay, D.P.2    Sargent, M.A.3    McNally, E.M.4    Molkentin, J.D.5
  • 6
    • 41149152962 scopus 로고    scopus 로고
    • Myostatin propeptide gene delivery by adeno-associated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice
    • C. Qiao, J. Li, J. Jiang, X. Zhu, B. Wang, and X. Xiao Myostatin propeptide gene delivery by adeno-associated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice Hum Gene Ther 19 2008 241 254
    • (2008) Hum Gene Ther , vol.19 , pp. 241-254
    • Qiao, C.1    Li, J.2    Jiang, J.3    Zhu, X.4    Wang, B.5    Xiao, X.6
  • 7
    • 14044279926 scopus 로고    scopus 로고
    • Muscle regeneration in the prolonged absence of myostatin
    • K.R. Wagner, X. Liu, X. Chang, and R.E. Allen Muscle regeneration in the prolonged absence of myostatin Proc Natl Acad Sci U S A 102 2005 2519 2524
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2519-2524
    • Wagner, K.R.1    Liu, X.2    Chang, X.3    Allen, R.E.4
  • 9
    • 0141768237 scopus 로고    scopus 로고
    • Myostatin negatively regulates satellite cell activation and self-renewal
    • S. McCroskery, M. Thomas, L. Maxwell, M. Sharma, and R. Kambadur Myostatin negatively regulates satellite cell activation and self-renewal J Cell Biol 162 2003 1135 1147
    • (2003) J Cell Biol , vol.162 , pp. 1135-1147
    • McCroskery, S.1    Thomas, M.2    Maxwell, L.3    Sharma, M.4    Kambadur, R.5
  • 10
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • A.C. McPherron, A.M. Lawler, and S.J. Lee Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member Nature 387 1997 83 90
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 11
    • 0034487730 scopus 로고    scopus 로고
    • Localization of activin beta(A)-, beta(B)-, and beta(C)-subunits in human prostate and evidence for formation of new activin heterodimers of beta(C)-subunit
    • S.L. Mellor, M. Cranfield, R. Ries, J. Pedersen, B. Cancilla, D. de Kretser, N.P. Groome, A.J. Mason, and G.P. Risbridger Localization of activin beta(A)-, beta(B)-, and beta(C)-subunits in human prostate and evidence for formation of new activin heterodimers of beta(C)-subunit J Clin Endocrinol Metab 85 2000 4851 4858
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4851-4858
    • Mellor, S.L.1    Cranfield, M.2    Ries, R.3    Pedersen, J.4    Cancilla, B.5    De Kretser, D.6    Groome, N.P.7    Mason, A.J.8    Risbridger, G.P.9
  • 15
    • 0025373853 scopus 로고
    • Requirement for activin A and transforming growth factor-beta 1 pro-regions in homodimer assembly
    • A.M. Gray, and A.J. Mason Requirement for activin A and transforming growth factor-beta 1 pro-regions in homodimer assembly Science 247 1990 1328 1330
    • (1990) Science , vol.247 , pp. 1328-1330
    • Gray, A.M.1    Mason, A.J.2
  • 16
    • 0026527384 scopus 로고
    • Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors
    • L. Attisano, J.L. Wrana, S. Cheifetz, and J. Massague Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors Cell 68 1992 97 108
    • (1992) Cell , vol.68 , pp. 97-108
    • Attisano, L.1    Wrana, J.L.2    Cheifetz, S.3    Massague, J.4
  • 17
    • 77956504043 scopus 로고    scopus 로고
    • Activin A and bone metastasis
    • G. Leto Activin A and bone metastasis J Cell Physiol 225 2010 302 309
    • (2010) J Cell Physiol , vol.225 , pp. 302-309
    • Leto, G.1
  • 20
    • 84867135322 scopus 로고    scopus 로고
    • Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival: No alterations post-lenalidomide and dexamethasone therapy
    • E. Terpos, E. Kastritis, D. Christoulas, M. Gkotzamanidou, E. Eleutherakis-Papaiakovou, N. Kanellias, A. Papatheodorou, and M.A. Dimopoulos Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival: no alterations post-lenalidomide and dexamethasone therapy Ann Oncol 23 2012 2681 2686
    • (2012) Ann Oncol , vol.23 , pp. 2681-2686
    • Terpos, E.1    Kastritis, E.2    Christoulas, D.3    Gkotzamanidou, M.4    Eleutherakis-Papaiakovou, E.5    Kanellias, N.6    Papatheodorou, A.7    Dimopoulos, M.A.8
  • 22
    • 38349145459 scopus 로고    scopus 로고
    • Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways
    • S.J. Lee Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways PLoS One 2 2007 e789
    • (2007) PLoS One , vol.2 , pp. 789
    • Lee, S.J.1
  • 24
    • 67650071006 scopus 로고    scopus 로고
    • Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin
    • H. Gilson, O. Schakman, S. Kalista, P. Lause, K. Tsuchida, and J.P. Thissen Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin Am J Physiol Endocrinol Metab 297 2009 E157 E164
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Gilson, H.1    Schakman, O.2    Kalista, S.3    Lause, P.4    Tsuchida, K.5    Thissen, J.P.6
  • 25
    • 0035979253 scopus 로고    scopus 로고
    • Regulation of myostatin activity and muscle growth
    • S.J. Lee, and A.C. McPherron Regulation of myostatin activity and muscle growth Proc Natl Acad Sci U S A 98 2001 9306 9311
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 9306-9311
    • Lee, S.J.1    McPherron, A.C.2
  • 26
    • 36049023174 scopus 로고    scopus 로고
    • Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia
    • K.L. Jones, A. Mansell, S. Patella, B.J. Scott, M.P. Hedger, D.M. de Kretser, and D.J. Phillips Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia Proc Natl Acad Sci U S A 104 2007 16239 16244
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 16239-16244
    • Jones, K.L.1    Mansell, A.2    Patella, S.3    Scott, B.J.4    Hedger, M.P.5    De Kretser, D.M.6    Phillips, D.J.7
  • 27
    • 63749105935 scopus 로고    scopus 로고
    • Activin and related proteins in inflammation: Not just interested bystanders
    • D.J. Phillips, D.M. de Kretser, and M.P. Hedger Activin and related proteins in inflammation: not just interested bystanders Cytokine Growth Factor Rev 20 2009 153 164
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 153-164
    • Phillips, D.J.1    De Kretser, D.M.2    Hedger, M.P.3
  • 30
    • 0028485090 scopus 로고
    • Relationship between muscle fiber types and sizes and muscle architectural properties in the mouse hindlimb
    • T.J. Burkholder, B. Fingado, S. Baron, and R.L. Lieber Relationship between muscle fiber types and sizes and muscle architectural properties in the mouse hindlimb J Morphol 221 1994 177 190
    • (1994) J Morphol , vol.221 , pp. 177-190
    • Burkholder, T.J.1    Fingado, B.2    Baron, S.3    Lieber, R.L.4
  • 31
    • 0347989458 scopus 로고    scopus 로고
    • Cellular and molecular regulation of muscle regeneration
    • S.B. Charge, and M.A. Rudnicki Cellular and molecular regulation of muscle regeneration Physiol Rev 84 2004 209 238
    • (2004) Physiol Rev , vol.84 , pp. 209-238
    • Charge, S.B.1    Rudnicki, M.A.2
  • 32
    • 0031571639 scopus 로고    scopus 로고
    • Persistent expression of MNF identifies myogenic stem cells in postnatal muscles
    • D.J. Garry, Q. Yang, R. Bassel-Duby, and R.S. Williams Persistent expression of MNF identifies myogenic stem cells in postnatal muscles Dev Biol 188 1997 280 294
    • (1997) Dev Biol , vol.188 , pp. 280-294
    • Garry, D.J.1    Yang, Q.2    Bassel-Duby, R.3    Williams, R.S.4
  • 33
    • 0142031110 scopus 로고    scopus 로고
    • Muscle injuries and repair: The role of prostaglandins and inflammation
    • V. Prisk, and J. Huard Muscle injuries and repair: the role of prostaglandins and inflammation Histol Histopathol 18 2003 1243 1256
    • (2003) Histol Histopathol , vol.18 , pp. 1243-1256
    • Prisk, V.1    Huard, J.2
  • 34
    • 0036563345 scopus 로고    scopus 로고
    • Muscle injuries and repair: Current trends in research
    • J. Huard, Y. Li, and F.H. Fu Muscle injuries and repair: current trends in research J Bone Joint Surg Am 84-A 2002 822 832
    • (2002) J Bone Joint Surg Am , vol.84 A , pp. 822-832
    • Huard, J.1    Li, Y.2    Fu, F.H.3
  • 35
    • 0035917850 scopus 로고    scopus 로고
    • Gene therapy for streptozotocin-induced diabetic mice by electroporational transfer of naked human insulin precursor DNA into skeletal muscle in vivo
    • D. Yin, and J.G. Tang Gene therapy for streptozotocin-induced diabetic mice by electroporational transfer of naked human insulin precursor DNA into skeletal muscle in vivo FEBS Lett 495 2001 16 20
    • (2001) FEBS Lett , vol.495 , pp. 16-20
    • Yin, D.1    Tang, J.G.2
  • 36
    • 33748173286 scopus 로고    scopus 로고
    • Simultaneous gene transfer of bone morphogenetic protein (BMP)-2 and BMP-7 by in vivo electroporation induces rapid bone formation and BMP-4 expression
    • M. Kawai, K. Bessho, H. Maruyama, J. Miyazaki, and T. Yamamoto Simultaneous gene transfer of bone morphogenetic protein (BMP)-2 and BMP-7 by in vivo electroporation induces rapid bone formation and BMP-4 expression BMC Musculoskelet Disord 7 2006 62
    • (2006) BMC Musculoskelet Disord , vol.7 , pp. 62
    • Kawai, M.1    Bessho, K.2    Maruyama, H.3    Miyazaki, J.4    Yamamoto, T.5
  • 38
    • 0030012410 scopus 로고    scopus 로고
    • The macrophage cell surface glycoprotein F4/80 is a highly glycosylated proteoglycan
    • I.D. Haidl, and W.A. Jefferies The macrophage cell surface glycoprotein F4/80 is a highly glycosylated proteoglycan Eur J Immunol 26 1996 1139 1146
    • (1996) Eur J Immunol , vol.26 , pp. 1139-1146
    • Haidl, I.D.1    Jefferies, W.A.2
  • 39
    • 83455244712 scopus 로고    scopus 로고
    • The TWEAK-Fn14 system: Breaking the silence of cytokine-induced skeletal muscle wasting
    • S. Bhatnagar, and A. Kumar The TWEAK-Fn14 system: breaking the silence of cytokine-induced skeletal muscle wasting Curr Mol Med 12 2012 3 13
    • (2012) Curr Mol Med , vol.12 , pp. 3-13
    • Bhatnagar, S.1    Kumar, A.2
  • 42
    • 84860347786 scopus 로고    scopus 로고
    • Myostatin inhibition induces muscle fibre hypertrophy prior to satellite cell activation
    • Q. Wang, and A.C. McPherron Myostatin inhibition induces muscle fibre hypertrophy prior to satellite cell activation J Physiol 590 2012 2151 2165
    • (2012) J Physiol , vol.590 , pp. 2151-2165
    • Wang, Q.1    McPherron, A.C.2
  • 44
    • 84897911263 scopus 로고    scopus 로고
    • Edited by RA Pagon, TD Bird, CR Dolan, K Stephens, MP Adam. In GeneReviews [Internet]. Copyright University of Washington, Seattle. 1993. Available at, last revised July 3
    • Wagner KR: Myostatin-Related Muscle Hypertrophy. Edited by RA Pagon, TD Bird, CR Dolan, K Stephens, MP Adam. In GeneReviews [Internet]. Copyright University of Washington, Seattle. 1993. Available at http://www.ncbi.nlm.nih. gov/books/NBK1499, last revised July 3, 2013
    • (2013) Myostatin-Related Muscle Hypertrophy
    • Wagner, K.R.1
  • 46
    • 0034923715 scopus 로고    scopus 로고
    • The role of tumor necrosis factor-alpha (TNF-alpha) in skeletal muscle regeneration: Studies in TNF-alpha(-/-) and TNF-alpha(-/-)/LT-alpha(-/-) mice
    • R.A. Collins, and M.D. Grounds The role of tumor necrosis factor-alpha (TNF-alpha) in skeletal muscle regeneration: studies in TNF-alpha(-/-) and TNF-alpha(-/-)/LT-alpha(-/-) mice J Histochem Cytochem 49 2001 989 1001
    • (2001) J Histochem Cytochem , vol.49 , pp. 989-1001
    • Collins, R.A.1    Grounds, M.D.2
  • 47
    • 84882645143 scopus 로고    scopus 로고
    • Monocyte/macrophage interactions with myogenic precursor cells during skeletal muscle regeneration
    • M. Saclier, S. Cuvellier, M. Magnan, R. Mounier, and B. Chazaud Monocyte/macrophage interactions with myogenic precursor cells during skeletal muscle regeneration FEBS J 280 2013 4118 4130
    • (2013) FEBS J , vol.280 , pp. 4118-4130
    • Saclier, M.1    Cuvellier, S.2    Magnan, M.3    Mounier, R.4    Chazaud, B.5
  • 49
    • 34248997759 scopus 로고    scopus 로고
    • Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
    • L. Arnold, A. Henry, F. Poron, Y. Baba-Amer, N. van Rooijen, A. Plonquet, R.K. Gherardi, and B. Chazaud Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis J Exp Med 204 2007 1057 1069
    • (2007) J Exp Med , vol.204 , pp. 1057-1069
    • Arnold, L.1    Henry, A.2    Poron, F.3    Baba-Amer, Y.4    Van Rooijen, N.5    Plonquet, A.6    Gherardi, R.K.7    Chazaud, B.8
  • 50
    • 79955958973 scopus 로고    scopus 로고
    • Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers
    • E. Sierra-Filardi, A. Puig-Kroger, F.J. Blanco, C. Nieto, R. Bragado, M.I. Palomero, C. Bernabeu, M.A. Vega, and A.L. Corbi Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers Blood 117 2011 5092 5101
    • (2011) Blood , vol.117 , pp. 5092-5101
    • Sierra-Filardi, E.1    Puig-Kroger, A.2    Blanco, F.J.3    Nieto, C.4    Bragado, R.5    Palomero, M.I.6    Bernabeu, C.7    Vega, M.A.8    Corbi, A.L.9
  • 54
    • 42949160019 scopus 로고    scopus 로고
    • The TWEAK-Fn14 cytokine-receptor axis: Discovery, biology and therapeutic targeting
    • J.A. Winkles The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting Nat Rev Drug Discov 7 2008 411 425
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 411-425
    • Winkles, J.A.1
  • 55
    • 77952315857 scopus 로고    scopus 로고
    • T helper 17 cells: Discovery, function, and physiological trigger
    • M.B. Torchinsky, and J.M. Blander T helper 17 cells: discovery, function, and physiological trigger Cell Mol Life Sci 67 2010 1407 1421
    • (2010) Cell Mol Life Sci , vol.67 , pp. 1407-1421
    • Torchinsky, M.B.1    Blander, J.M.2
  • 57
    • 84872290003 scopus 로고    scopus 로고
    • Interleukin-17 modulates myoblast cell migration by inhibiting urokinase type plasminogen activator expression through p38 mitogen-activated protein kinase
    • J. Kocic, J.F. Santibanez, A. Krstic, S. Mojsilovic, V. Ilic, and D. Bugarski Interleukin-17 modulates myoblast cell migration by inhibiting urokinase type plasminogen activator expression through p38 mitogen-activated protein kinase Int J Biochem Cell Biol 45 2013 464 475
    • (2013) Int J Biochem Cell Biol , vol.45 , pp. 464-475
    • Kocic, J.1    Santibanez, J.F.2    Krstic, A.3    Mojsilovic, S.4    Ilic, V.5    Bugarski, D.6
  • 58
  • 61
    • 53149116307 scopus 로고    scopus 로고
    • Inhibition of myoblast differentiation by tumor necrosis factor alpha is mediated by c-Jun N-terminal kinase 1 and leukemia inhibitory factor
    • J. Alter, D. Rozentzweig, and E. Bengal Inhibition of myoblast differentiation by tumor necrosis factor alpha is mediated by c-Jun N-terminal kinase 1 and leukemia inhibitory factor J Biol Chem 283 2008 23224 23234
    • (2008) J Biol Chem , vol.283 , pp. 23224-23234
    • Alter, J.1    Rozentzweig, D.2    Bengal, E.3
  • 62
    • 0032412058 scopus 로고    scopus 로고
    • Activation of the skeletal alpha-actin promoter during muscle regeneration
    • D.R. Marsh, J.A. Carson, L.N. Stewart, and F.W. Booth Activation of the skeletal alpha-actin promoter during muscle regeneration J Muscle Res Cell Motil 19 1998 897 907
    • (1998) J Muscle Res Cell Motil , vol.19 , pp. 897-907
    • Marsh, D.R.1    Carson, J.A.2    Stewart, L.N.3    Booth, F.W.4
  • 64
    • 0032871622 scopus 로고    scopus 로고
    • Myostatin and the control of skeletal muscle mass
    • S.J. Lee, and A.C. McPherron Myostatin and the control of skeletal muscle mass Curr Opin Genet Dev 9 1999 604 607
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 604-607
    • Lee, S.J.1    McPherron, A.C.2
  • 66
    • 34547119523 scopus 로고    scopus 로고
    • Myostatin blockade: A new way to enhance skeletal muscle repair in old age?
    • Z. Yablonka-Reuveni Myostatin blockade: a new way to enhance skeletal muscle repair in old age? Mol Ther 15 2007 1407 1409
    • (2007) Mol Ther , vol.15 , pp. 1407-1409
    • Yablonka-Reuveni, Z.1
  • 67
    • 66749094712 scopus 로고    scopus 로고
    • Myostatin and muscle fiber size: Focus on "smad2 and 3 transcription factors control muscle mass in adulthood" and "myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size."
    • S.L. Welle Myostatin and muscle fiber size: focus on "Smad2 and 3 transcription factors control muscle mass in adulthood" and "Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size." Am J Physiol Cell Physiol 296 2009 C1245 C1247
    • (2009) Am J Physiol Cell Physiol , vol.296
    • Welle, S.L.1


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