Design and characterization of a chimeric multiepitope construct containing CfaB, heat-stable toxoid, CssA, CssB, and heat-labile toxin subunit B of enterotoxigenic Escherichia coli: A bioinformatic approach

Biotechnology and Applied Biochemistry

Volumn 61, Issue 5, 2014, Pages 517-527

  Zeinalzadeh, Narges ^a   Salmanian, Ali Hatef ^a   Ahangari, Ghasem ^a   Sadeghi, Mahdi ^a   Amani, Jafar ^b   Bathaie, S Zahra ^c   Jafari, Mahyat ^a  

^a NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

^b BAQIYATALLAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

bioinformatics analysis; chimeric protein; enterotoxigenic Escherichia coli; immunogenicity

Indexed keywords

DEVELOPING COUNTRIES; ESCHERICHIA COLI; GENES; PROTEINS; VACCINES;

BIOINFORMATIC TOOLS; BIOINFORMATICS ANALYSIS; CHIMERIC PROTEINS; ENTEROTOXIGENIC ESCHERICHIA COLI; EXPERIMENTAL METHODS; IMMUNOGENICITY; PURIFIED PROTEIN; VIRULENCE FACTORS;

BIOINFORMATICS;

BLOOD GROUP I ANTIGEN; CHIMERIC PROTEIN; COLI SURFACE ANTIGEN SUBUNIT A; COLI SURFACE ANTIGEN SUBUNIT B; COLONIZATION FACTOR ANTIGEN B; EPITOPE; ESCHERICHIA COLI ENTEROTOXIN; ESCHERICHIA COLI ENTEROTOXIN SUBUNIT B; ESCHERICHIA COLI VACCINE; HLA A ANTIGEN; HLA A7 ANTIGEN; HLA B13 ANTIGEN; MEMBRANE ANTIGEN; MESSENGER RNA; SUBUNIT VACCINE; UNCLASSIFIED DRUG; VIRULENCE FACTOR; BACTERIAL TOXIN; ENTEROTOXIN; ESCHERICHIA COLI PROTEIN; HYBRID PROTEIN;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ALLERGENICITY; ANTIGENICITY; ARTICLE; ARTIFICIAL NEURAL NETWORK; B LYMPHOCYTE; BACTERIAL COLONIZATION; BACTERIAL VIRULENCE; CHIMERA; CODON; DNA BASE COMPOSITION; DRUG ANALYSIS; DRUG DESIGN; ENTEROTOXIGENIC ESCHERICHIA COLI; EXPRESSION VECTOR; GENE EXPRESSION; GENE SEQUENCE; GENETIC HETEROGENEITY; HLA SYSTEM; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; RESTRICTION SITE; RNA STABILITY; T LYMPHOCYTE; THERMOSTABILITY; AMINO ACID SEQUENCE; BIOLOGY; CHEMISTRY; GENETICS; IMMUNOLOGY; MOLECULAR GENETICS; PROCEDURES; PROTEIN ENGINEERING;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; PROKARYOTA;

AMINO ACID SEQUENCE; BACTERIAL TOXINS; COMPUTATIONAL BIOLOGY; ENTEROTOXIGENIC ESCHERICHIA COLI; ENTEROTOXINS; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; ESCHERICHIA COLI PROTEINS; ESCHERICHIA COLI VACCINES; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS;

EID: 84931343455     PISSN: 08854513     EISSN: 14708744     Source Type: Journal    
DOI: 10.1002/bab.1196     Document Type: Article

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