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Volumn 78, Issue 1, 2010, Pages 316-325

Genetic fusions of heat-labile (LT) and heat-stable (ST) toxoids of porcine enterotoxigenic Escherichia coli elicit neutralizing anti-LT and anti-STa antibodies

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTISERUM; BACTERIAL TOXIN; CHOLERA TOXIN; ENTEROTOXIN; HYBRID PROTEIN; NEUTRALIZING ANTIBODY;

EID: 73449147008     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00497-09     Document Type: Article
Times cited : (71)

References (51)
  • 1
    • 0001736709 scopus 로고
    • Neonatal diarrhoea in pigs
    • C. L. Gyles ed, CAB International, Oxon, United Kingdom
    • Alexander, T. J. L. 1994. Neonatal diarrhoea in pigs, p. 151-170. In C. L. Gyles (ed.), Escherichia coli in domestic animals and humans. CAB International, Oxon, United Kingdom.
    • (1994) Escherichia coli in domestic animals and humans , pp. 151-170
    • Alexander, T.J.L.1
  • 2
    • 0034938201 scopus 로고    scopus 로고
    • Synthesis of a cholera toxin B subunit-rotavirus NSP4 fusion protein in potato
    • Arakawa, R., J. Yu, and W. H. R. Langridge. 2001. Synthesis of a cholera toxin B subunit-rotavirus NSP4 fusion protein in potato. Plant Cell Rep. 20:343-348.
    • (2001) Plant Cell Rep , vol.20 , pp. 343-348
    • Arakawa, R.1    Yu, J.2    Langridge, W.H.R.3
  • 4
    • 0034669389 scopus 로고    scopus 로고
    • Contribution of defined amino acid residues to the immunogenicity of recombinant Escherichia coli heat-stable enterotoxin fusion proteins
    • Batisson, I., and M. Der Vartinian. 2000. Contribution of defined amino acid residues to the immunogenicity of recombinant Escherichia coli heat-stable enterotoxin fusion proteins. FEMS Microbiol. Lett. 192:223-229.
    • (2000) FEMS Microbiol. Lett , vol.192 , pp. 223-229
    • Batisson, I.1    Der Vartinian, M.2
  • 5
    • 0033932494 scopus 로고    scopus 로고
    • Full capacity of recombinant Escherichia coli heat-stable enterotoxin fusion proteins for extracellular secretion, antigenicity, disulfide bond formation and activity
    • Batisson, I., M. Der Vartanian, B. Gaillard-Martinie, and M. Contrepois. 2000. Full capacity of recombinant Escherichia coli heat-stable enterotoxin fusion proteins for extracellular secretion, antigenicity, disulfide bond formation and activity. Infect. Immun. 68:4064-4074.
    • (2000) Infect. Immun , vol.68 , pp. 4064-4074
    • Batisson, I.1    Der Vartanian, M.2    Gaillard-Martinie, B.3    Contrepois, M.4
  • 6
    • 3042681631 scopus 로고    scopus 로고
    • Relative importance of heat-labile enterotoxin in the causation of severe diarrheal disease in the gnotobiotic piglet model by a strain of enterotoxigenic Escherichia coli that produces multiple enterotoxins
    • Berberov, E. M., Y. Zhou, D. H. Francis, M. A. Scott, S. D. Kachman, and R. A. Moxley. 2004. Relative importance of heat-labile enterotoxin in the causation of severe diarrheal disease in the gnotobiotic piglet model by a strain of enterotoxigenic Escherichia coli that produces multiple enterotoxins. Infect. Immun. 72:3914-3924.
    • (2004) Infect. Immun , vol.72 , pp. 3914-3924
    • Berberov, E.M.1    Zhou, Y.2    Francis, D.H.3    Scott, M.A.4    Kachman, S.D.5    Moxley, R.A.6
  • 7
    • 13244272289 scopus 로고    scopus 로고
    • Vaccines for enterotoxigenic Escherichia coli: Current status
    • Boedeker, E. C. 2005. Vaccines for enterotoxigenic Escherichia coli: current status. Curr. Opin. Gastroenterol. 21:15-19.
    • (2005) Curr. Opin. Gastroenterol , vol.21 , pp. 15-19
    • Boedeker, E.C.1
  • 8
    • 0032725454 scopus 로고    scopus 로고
    • Lysine residue 117 of the FasG adhesin of enterotoxigenic Escherichia coli is essential for binding of 987P fimbriae to sulfatide
    • Choi, B. K., and D. M. Schifferli. 1999. Lysine residue 117 of the FasG adhesin of enterotoxigenic Escherichia coli is essential for binding of 987P fimbriae to sulfatide. Infect. Immun. 67:5755-5761.
    • (1999) Infect. Immun , vol.67 , pp. 5755-5761
    • Choi, B.K.1    Schifferli, D.M.2
  • 9
    • 0025305320 scopus 로고
    • Construction of a nontoxic fusion peptide for immunization against Escherichia coli strains that produce heat-labile and heat-stable enterotoxins
    • Clements, J. D. 1990. Construction of a nontoxic fusion peptide for immunization against Escherichia coli strains that produce heat-labile and heat-stable enterotoxins. Infect. Immun. 58:1159-1166.
    • (1990) Infect. Immun , vol.58 , pp. 1159-1166
    • Clements, J.D.1
  • 10
    • 0036059930 scopus 로고    scopus 로고
    • Enterotoxigenic Escherichia coli infection in pigs and its diagnosis
    • Francis, D. H. 2002. Enterotoxigenic Escherichia coli infection in pigs and its diagnosis. J. Swine Health Prod. 10:171-175.
    • (2002) J. Swine Health Prod , vol.10 , pp. 171-175
    • Francis, D.H.1
  • 11
    • 0025807889 scopus 로고
    • A live avirulent Escherichia coli vaccine for K88+ enterotoxigenic colibacillosis in weaned pigs
    • Francis, D. H., and J. A. Willgohs. 1991. A live avirulent Escherichia coli vaccine for K88+ enterotoxigenic colibacillosis in weaned pigs. Am. J. Vet. Res. 52:1051-1055.
    • (1991) Am. J. Vet. Res , vol.52 , pp. 1051-1055
    • Francis, D.H.1    Willgohs, J.A.2
  • 12
    • 73449129190 scopus 로고
    • Production and testing of Escherichia coli (LTb) toxoid
    • S. Acres ed, VIDO Publications, Saskatoon, Saskatchewan, Canada
    • Frantz, J. C., and M. W. Mellencamp. 1983. Production and testing of Escherichia coli (LTb) toxoid, p. 500-517. In S. Acres (ed.), Proceedings of the Fourth International Symposium on Neonatal Diarrhea. VIDO Publications, Saskatoon, Saskatchewan, Canada.
    • (1983) Proceedings of the Fourth International Symposium on Neonatal Diarrhea , pp. 500-517
    • Frantz, J.C.1    Mellencamp, M.W.2
  • 13
    • 0019503847 scopus 로고
    • Immunological properties of Escherichia coli heat-stable enterotoxins: Development of a radioimmunoassay specific for heat-stable enterotoxins with suckling mouse activity
    • Frantz, J. C., and D. C. Robertson. 1981. Immunological properties of Escherichia coli heat-stable enterotoxins: development of a radioimmunoassay specific for heat-stable enterotoxins with suckling mouse activity. Infect. Immun. 33:193-198.
    • (1981) Infect. Immun , vol.33 , pp. 193-198
    • Frantz, J.C.1    Robertson, D.C.2
  • 14
    • 44949230030 scopus 로고    scopus 로고
    • Frech, S. A., H. L. DuPont, A. L. Bourgeois, R. McKenzie, J. Belkind-Gerson, J. F. Figueroa, P. C. Okhuysen, N. H. Guerrero, F. G. Martinez-Sandoval, J. H. M. Melendez-Romero, Z.-D. Jiang, E. J. Asturias, J. Halpern, O. R. Torres, A. S. Hoffman, C. P. Villar, R. N. Kassem, D. C., Flyer, B. H. Andersen, K. Kazempour, S. A. Breisch, and G. M. Glenn. 2008. Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhea: a phase II, randomized, double-blind, placebo-controlled field trial. Lancet 371:2019-2025.
    • Frech, S. A., H. L. DuPont, A. L. Bourgeois, R. McKenzie, J. Belkind-Gerson, J. F. Figueroa, P. C. Okhuysen, N. H. Guerrero, F. G. Martinez-Sandoval, J. H. M. Melendez-Romero, Z.-D. Jiang, E. J. Asturias, J. Halpern, O. R. Torres, A. S. Hoffman, C. P. Villar, R. N. Kassem, D. C., Flyer, B. H. Andersen, K. Kazempour, S. A. Breisch, and G. M. Glenn. 2008. Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhea: a phase II, randomized, double-blind, placebo-controlled field trial. Lancet 371:2019-2025.
  • 15
    • 0036498627 scopus 로고    scopus 로고
    • Prevalence of serogroups and virulence genes in Escherichia coli associated with postweaning diarrhoea and edema disease in pigs and a comparison of diagnostic approaches
    • Frydendahl, K. 2002. Prevalence of serogroups and virulence genes in Escherichia coli associated with postweaning diarrhoea and edema disease in pigs and a comparison of diagnostic approaches. Vet. Microbiol. 85:169-182.
    • (2002) Vet. Microbiol , vol.85 , pp. 169-182
    • Frydendahl, K.1
  • 16
    • 33644915282 scopus 로고    scopus 로고
    • A review of vaccine research and development: Human enteric infections
    • Girard, M. P., D. Steele, C. L. Chaignat, and M. P. Kieny. 2006. A review of vaccine research and development: human enteric infections. Vaccine 24: 2732-2750.
    • (2006) Vaccine , vol.24 , pp. 2732-2750
    • Girard, M.P.1    Steele, D.2    Chaignat, C.L.3    Kieny, M.P.4
  • 17
    • 0023449909 scopus 로고
    • Fusion of Escherichia coli heat-stable enterotoxin and heat-labile enterotoxin B subunit
    • Guzman-Verduzco, L., and Y. M. Kupersztoch. 1987. Fusion of Escherichia coli heat-stable enterotoxin and heat-labile enterotoxin B subunit. J. Bacteriol. 169:5201-5208.
    • (1987) J. Bacteriol , vol.169 , pp. 5201-5208
    • Guzman-Verduzco, L.1    Kupersztoch, Y.M.2
  • 18
    • 33750576453 scopus 로고    scopus 로고
    • Use of competitive exclusion to control enterotoxigenic strains of Escherichia coli in weaned pigs
    • Harvey, R. B., R. C. Anderson, K. J. Genovese, T. R. Callaway, and D. J. Nisbet. 2005. Use of competitive exclusion to control enterotoxigenic strains of Escherichia coli in weaned pigs. J. Anim. Sci. 83:44-47.
    • (2005) J. Anim. Sci , vol.83 , pp. 44-47
    • Harvey, R.B.1    Anderson, R.C.2    Genovese, K.J.3    Callaway, T.R.4    Nisbet, D.J.5
  • 19
    • 0001584589 scopus 로고
    • Heat-stable enterotoxin of Escherichia coli
    • J. Moss, B. Iglewski, M. Vaughan, and A. T. Tu ed, Marcel Dekker, Inc, New York, NY
    • Hirayama, T. 1995. Heat-stable enterotoxin of Escherichia coli, p. 281-296. In J. Moss, B. Iglewski, M. Vaughan, and A. T. Tu (ed.), Bacterial toxins and virulence factors in disease. Marcel Dekker, Inc., New York, NY.
    • (1995) Bacterial toxins and virulence factors in disease , pp. 281-296
    • Hirayama, T.1
  • 20
    • 73449098792 scopus 로고    scopus 로고
    • Hol, W. G. J., T. K. Sixma, and E. A. Merritt. 1995. Structure and function of E. coli heat-labile enterotoxin and cholera toxin B pentamer, p. 185-223. In J. Moss, B. Iglewski, M. Vaughan, and A. T. Tu (ed.), Bacterial toxins and virulence factors in disease. Marcel Dekker, Inc., New York, NY.
    • Hol, W. G. J., T. K. Sixma, and E. A. Merritt. 1995. Structure and function of E. coli heat-labile enterotoxin and cholera toxin B pentamer, p. 185-223. In J. Moss, B. Iglewski, M. Vaughan, and A. T. Tu (ed.), Bacterial toxins and virulence factors in disease. Marcel Dekker, Inc., New York, NY.
  • 21
    • 0018100207 scopus 로고
    • Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli
    • Hughes, J. M., F. Murad, B. Chang, and R. L. Guerrant. 1978. Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli. Nature 271:755-756.
    • (1978) Nature , vol.271 , pp. 755-756
    • Hughes, J.M.1    Murad, F.2    Chang, B.3    Guerrant, R.L.4
  • 22
    • 3242721681 scopus 로고    scopus 로고
    • Guide for the care and use of laboratory animals. National Academy Press, Washington, DC
    • Institute of Laboratory Animal Resources. 1996. Guide for the care and use of laboratory animals. National Academy Press, Washington, DC.
    • (1996) Institute of Laboratory Animal Resources
  • 23
    • 0020025609 scopus 로고
    • Development of a vaccine of cross-linked heat-stable and heat-labile enterotoxin that protects against Escherichia coli producing either enterotoxin
    • Klipstein, F. A., R. F. Engert, and J. D. Clements. 1982. Development of a vaccine of cross-linked heat-stable and heat-labile enterotoxin that protects against Escherichia coli producing either enterotoxin. Infect. Immun. 37:550-557.
    • (1982) Infect. Immun , vol.37 , pp. 550-557
    • Klipstein, F.A.1    Engert, R.F.2    Clements, J.D.3
  • 26
    • 0021674360 scopus 로고
    • Development of a competitive enzyme-linked immunosorbent assay (ELISA) for Escherichia coli heat-stable enterotoxin (STa)
    • Lockwood, D. E., and D. C. Robertson. 1984. Development of a competitive enzyme-linked immunosorbent assay (ELISA) for Escherichia coli heat-stable enterotoxin (STa). J. Immunol. Methods 75:293-307.
    • (1984) J. Immunol. Methods , vol.75 , pp. 293-307
    • Lockwood, D.E.1    Robertson, D.C.2
  • 27
    • 0017797812 scopus 로고
    • Mechanisms in the pathogenesis of diarrhea: A review
    • Moon, H. W. 1978. Mechanisms in the pathogenesis of diarrhea: a review. J. Am. Vet. Med. Assoc. 172:443-448.
    • (1978) J. Am. Vet. Med. Assoc , vol.172 , pp. 443-448
    • Moon, H.W.1
  • 28
    • 0025213118 scopus 로고
    • Colonization factor antigens of enterotoxigenic Escherichia coli in animals
    • Moon, H. W. 1990. Colonization factor antigens of enterotoxigenic Escherichia coli in animals. Curr. Top. Microbiol. Immunol. 151:147-165.
    • (1990) Curr. Top. Microbiol. Immunol , vol.151 , pp. 147-165
    • Moon, H.W.1
  • 29
    • 0027395992 scopus 로고
    • Vaccines for preventing enterotoxigenic Escherichia coli infections in farm animals
    • Moon, H. W., and T. O. Bunn. 1993. Vaccines for preventing enterotoxigenic Escherichia coli infections in farm animals. Vaccine 11:213-220.
    • (1993) Vaccine , vol.11 , pp. 213-220
    • Moon, H.W.1    Bunn, T.O.2
  • 30
    • 0033987915 scopus 로고    scopus 로고
    • Prevalence of toxin types and colonization factors in enterotoxigenic Escherichia coli isolated during a 2-year period from diarrheal patients in Bangladesh
    • Qadri, F., S. K. Das, A. S. Faruque, G. J. Fuxhs, M. J. Albert, R. B. Sack, and A.-M. Svennerholm. 2000. Prevalence of toxin types and colonization factors in enterotoxigenic Escherichia coli isolated during a 2-year period from diarrheal patients in Bangladesh. J. Clin. Microbiol. 38:27-31.
    • (2000) J. Clin. Microbiol , vol.38 , pp. 27-31
    • Qadri, F.1    Das, S.K.2    Faruque, A.S.3    Fuxhs, G.J.4    Albert, M.J.5    Sack, R.B.6    Svennerholm, A.-M.7
  • 31
    • 4644268877 scopus 로고    scopus 로고
    • Real-time fluorescense PCR assays for detection and characterization of heat-labile I and heat-stable I enterotoxin genes from enterotoxigenic Escherichia coli
    • Reischl, U., M. T. Youssef, H. Wolf, E. Hyytia-Trees, and N. A. Strockbine. 2004. Real-time fluorescense PCR assays for detection and characterization of heat-labile I and heat-stable I enterotoxin genes from enterotoxigenic Escherichia coli. J. Clin. Microbiol. 42:4092-4100.
    • (2004) J. Clin. Microbiol , vol.42 , pp. 4092-4100
    • Reischl, U.1    Youssef, M.T.2    Wolf, H.3    Hyytia-Trees, E.4    Strockbine, N.A.5
  • 32
    • 0023903958 scopus 로고
    • Hybrid enterotoxin LTA:STa proteins and their protection from degradation by in vivo association with B-subunits of Escherichia coli heat-labile enterotoxin
    • Sanchez, J., T. R. Hirst, and B. E. Uhlin. 1988. Hybrid enterotoxin LTA:STa proteins and their protection from degradation by in vivo association with B-subunits of Escherichia coli heat-labile enterotoxin. Gene 64:265-275.
    • (1988) Gene , vol.64 , pp. 265-275
    • Sanchez, J.1    Hirst, T.R.2    Uhlin, B.E.3
  • 33
    • 0024272945 scopus 로고
    • Genetic fusion of a non-toxic heat-stable enterotoxin related decapeptide antigen to cholera toxin B-subunit
    • Sanchez, J., and J. Holmgren. 1988. Genetic fusion of a non-toxic heat-stable enterotoxin related decapeptide antigen to cholera toxin B-subunit. FEBS Lett. 241:110-114.
    • (1988) FEBS Lett , vol.241 , pp. 110-114
    • Sanchez, J.1    Holmgren, J.2
  • 34
    • 0022974852 scopus 로고
    • Immunoactive chimeric St-LT enterotoxins of Escherichia coli generated by in vitro gene fusion
    • Sanchez, J., B. E. Uhlin, T. Grundstrom, J. Holmgren, and T. R. Hirst. 1986. Immunoactive chimeric St-LT enterotoxins of Escherichia coli generated by in vitro gene fusion. FEBS Lett. 208:194-198.
    • (1986) FEBS Lett , vol.208 , pp. 194-198
    • Sanchez, J.1    Uhlin, B.E.2    Grundstrom, T.3    Holmgren, J.4    Hirst, T.R.5
  • 35
    • 0028121757 scopus 로고
    • Permissive linker insertion sites in the outer membrane protein of 987P fimbriae of Escherichia coli
    • Schifferli, D. M., and M. A. Alrutz. 1994. Permissive linker insertion sites in the outer membrane protein of 987P fimbriae of Escherichia coli. J. Bacteriol. 176:1099-1110.
    • (1994) J. Bacteriol , vol.176 , pp. 1099-1110
    • Schifferli, D.M.1    Alrutz, M.A.2
  • 36
    • 0029942531 scopus 로고    scopus 로고
    • Enteric bacterial toxins: Mechanisms of action and linkage to intestinal secretion
    • Sears, C. L., and J. B. Kaper. 1996. Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion. Microbiol. Rev. 60:167-215.
    • (1996) Microbiol. Rev , vol.60 , pp. 167-215
    • Sears, C.L.1    Kaper, J.B.2
  • 38
    • 0015155550 scopus 로고
    • Observation on the pathogenic properties of the K88, HIY and ENT plasmids of Escherichia coli with particular reference to porcine diarrhea
    • Smith, H. W., and M. A. Linggood. 1971. Observation on the pathogenic properties of the K88, HIY and ENT plasmids of Escherichia coli with particular reference to porcine diarrhea. J. Med. Microbiol. 4:467-485.
    • (1971) J. Med. Microbiol , vol.4 , pp. 467-485
    • Smith, H.W.1    Linggood, M.A.2
  • 39
    • 73449098376 scopus 로고
    • Immunity to enterotoxin-producing bacteria
    • T. T. MacDonald ed, Kluwer Academic Publishers, Dordrecht, The Netherlands
    • Svennerholm, A.-M., and J. Holmgren. 1992. Immunity to enterotoxin-producing bacteria, p. 227-246. In T. T. MacDonald (ed.), Immunology of gastrointestinal disease. Kluwer Academic Publishers, Dordrecht, The Netherlands.
    • (1992) Immunology of gastrointestinal disease , pp. 227-246
    • Svennerholm, A.-M.1    Holmgren, J.2
  • 40
    • 0001021175 scopus 로고
    • Oral B-subunit whole-cell vaccines against cholera and enterotoxigenic Escherichia coli diarrhea
    • D. A. A. AlaAldeen, and C. E. Hormaeche ed, John Wiley & Sons Ltd, Chicester, England
    • Svennerholm, A.-M., and J. Holmgren. 1995. Oral B-subunit whole-cell vaccines against cholera and enterotoxigenic Escherichia coli diarrhea, p. 205-232. In D. A. A. AlaAldeen, and C. E. Hormaeche (ed.), Molecular and clinical aspects of bacterial vaccine development. John Wiley & Sons Ltd., Chicester, England.
    • (1995) Molecular and clinical aspects of bacterial vaccine development , pp. 205-232
    • Svennerholm, A.-M.1    Holmgren, J.2
  • 41
    • 0023744104 scopus 로고
    • Synthesis of nontoxic, antibody-binding Escherichia coli heat-stable enterotoxin (STa) peptides
    • Svennerholm, A.-M., M. Lindblad, B. Svennerholm, and J. Holmgren. 1988. Synthesis of nontoxic, antibody-binding Escherichia coli heat-stable enterotoxin (STa) peptides. FEMS Microbiol. Lett. 55:23-28.
    • (1988) FEMS Microbiol. Lett , vol.55 , pp. 23-28
    • Svennerholm, A.-M.1    Lindblad, M.2    Svennerholm, B.3    Holmgren, J.4
  • 42
    • 0024366431 scopus 로고
    • Epidemiological studies of piglet diarrhoea in intensively managed Danish sow herds. II. Post-weaning diarrhoea
    • Svensmark, B., K. Nielsen, P. Willeberg, and S. E. Jorsal. 1989. Epidemiological studies of piglet diarrhoea in intensively managed Danish sow herds. II. Post-weaning diarrhoea. Acta Vet. Scand. 30:55-62.
    • (1989) Acta Vet. Scand , vol.30 , pp. 55-62
    • Svensmark, B.1    Nielsen, K.2    Willeberg, P.3    Jorsal, S.E.4
  • 43
    • 0033537867 scopus 로고    scopus 로고
    • Induction of immune responses in pigs following oral administration of purified F4 fimbriae
    • Van den Broeck, W., E. Cox, and B. M. Goddeeris. 1999. Induction of immune responses in pigs following oral administration of purified F4 fimbriae. Vaccine 17:2020-2029.
    • (1999) Vaccine , vol.17 , pp. 2020-2029
    • Van den Broeck, W.1    Cox, E.2    Goddeeris, B.M.3
  • 44
    • 17144390274 scopus 로고    scopus 로고
    • Considerations for development of whole cell bacterial vaccines to prevent diarrheal diseases in children in developing countries
    • Walker, R. I. 2005. Considerations for development of whole cell bacterial vaccines to prevent diarrheal diseases in children in developing countries. Vaccine 23:3369-3385.
    • (2005) Vaccine , vol.23 , pp. 3369-3385
    • Walker, R.I.1
  • 45
    • 0022671005 scopus 로고
    • Fimbriae and enterotoxins associated with Escherichia coli serogroups isolated from pigs with colibacillosis
    • Wilson, M. R., and D. H. Francis. 1986. Fimbriae and enterotoxins associated with Escherichia coli serogroups isolated from pigs with colibacillosis. Am. J. Vet. Res. 47:213-217.
    • (1986) Am. J. Vet. Res , vol.47 , pp. 213-217
    • Wilson, M.R.1    Francis, D.H.2
  • 46
    • 0030696287 scopus 로고    scopus 로고
    • Occurrence, distribution, and associations of O and H serogroups, colonization factor antigens, and toxin of enterotoxigenic Escherichia coli
    • Wolf, M. K. 1997. Occurrence, distribution, and associations of O and H serogroups, colonization factor antigens, and toxin of enterotoxigenic Escherichia coli. Clin. Microbiol. Rev. 10:569-584.
    • (1997) Clin. Microbiol. Rev , vol.10 , pp. 569-584
    • Wolf, M.K.1
  • 47
    • 0008393194 scopus 로고
    • Effects on the activity of amino acids replacement at positions 12, 13, and 14 heat-stable enterotoxin (STh) by chemical synthesis
    • Program Cholera Related Diarrheal Disease Panel, Tokyo, Japan
    • Yamasaki, S., H. Ito, T. Hirayama, Y. Takeda, and Y. Shimonishi. 1988. Effects on the activity of amino acids replacement at positions 12, 13, and 14 heat-stable enterotoxin (STh) by chemical synthesis, p. 42. Abstr. 24th Joint Conf. U.S.-Japan Cooperative Med. Sci. Program Cholera Related Diarrheal Disease Panel, Tokyo, Japan.
    • (1988) Abstr. 24th Joint Conf. U.S.-Japan Cooperative Med. Sci , pp. 42
    • Yamasaki, S.1    Ito, H.2    Hirayama, T.3    Takeda, Y.4    Shimonishi, Y.5
  • 48
    • 0025080303 scopus 로고
    • Structure-activity relationship of Escherichia coli heat-stable enterotoxin: Role of Ala residue at position 14 in toxin-receptor interaction
    • Yamasaki, S., T. Sato, Y. Hidaka, H. Ozaki, H. Ito, T. Hirayama, Y. Takeda, T. Sugimura, A. Tai, and Y. Shimonishi. 1990. Structure-activity relationship of Escherichia coli heat-stable enterotoxin: role of Ala residue at position 14 in toxin-receptor interaction. Bull. Chem. Soc. Jpn. 63:2063-2070.
    • (1990) Bull. Chem. Soc. Jpn , vol.63 , pp. 2063-2070
    • Yamasaki, S.1    Sato, T.2    Hidaka, Y.3    Ozaki, H.4    Ito, H.5    Hirayama, T.6    Takeda, Y.7    Sugimura, T.8    Tai, A.9    Shimonishi, Y.10
  • 49
    • 33646908791 scopus 로고    scopus 로고
    • Significance of heat-stable and heat-labile enterotoxins in porcine colibacillosis, in an additive model for pathogenicity studies
    • Zhang, W., E. M. Berberov, J. Freeling, D. He, R. A. Moxley, and D. H. Francis. 2006. Significance of heat-stable and heat-labile enterotoxins in porcine colibacillosis, in an additive model for pathogenicity studies. Infect. Immun. 74:3107-3114.
    • (2006) Infect. Immun , vol.74 , pp. 3107-3114
    • Zhang, W.1    Berberov, E.M.2    Freeling, J.3    He, D.4    Moxley, R.A.5    Francis, D.H.6
  • 50
    • 52649125764 scopus 로고    scopus 로고
    • Escherichia coli constructs expressing human or porcine enterotoxins induce identical diarrheal diseases in a piglet infection model
    • Zhang, W., D. C. Robertson, C. Zhang, W. Bai, M. Zhao, and D. H. Francis. 2008. Escherichia coli constructs expressing human or porcine enterotoxins induce identical diarrheal diseases in a piglet infection model. Appl. Environ. Microbiol. 74:5832-5837.
    • (2008) Appl. Environ. Microbiol , vol.74 , pp. 5832-5837
    • Zhang, W.1    Robertson, D.C.2    Zhang, C.3    Bai, W.4    Zhao, M.5    Francis, D.H.6
  • 51
    • 34250195741 scopus 로고    scopus 로고
    • Prevalence of virulence genes in Escherichia coli strains isolated from young pigs with diarrhea in the U.S
    • Zhang, W., M. Zhao, L. Ruesch, A. Omot, and D. H. Francis. 2007. Prevalence of virulence genes in Escherichia coli strains isolated from young pigs with diarrhea in the U.S. Vet. Microbiol. 123:145-152.
    • (2007) Vet. Microbiol , vol.123 , pp. 145-152
    • Zhang, W.1    Zhao, M.2    Ruesch, L.3    Omot, A.4    Francis, D.H.5


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