Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase

EMBO Journal

Volumn 34, Issue 12, 2015, Pages 1687-1703

  Zhao, Yu ^a   Majid, Mona C ^a   Soll, Jennifer M ^a   Brickner, Joshua R ^a   Dango, Sebastian ^b   Mosammaparast, Nima ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

AlkB; Alkylation OTUD4; Deubiquitinase; DNA repair

Indexed keywords

ALKB PROTEIN; ALKBH2 DEMETHYLASE; ALKBH3 DEMETHYLASE; DEUBIQUITINASE; DNA GLYCOSYLTRANSFERASE; OTU DOMAIN CONTAINING PROTEIN 4; UBIQUITIN; UNCLASSIFIED DRUG; USP7 PROTEIN; USP9X PROTEIN; ALKBH2 PROTEIN, HUMAN; ALKBH3 PROTEIN, HUMAN; DIOXYGENASE; DNA LIGASE; OTUD4 PROTEIN, HUMAN;

ARTICLE; CATALYSIS; CYTOTOXICITY ASSAY; DNA ALKYLATION; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONCANONICAL REGULATION; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; PROTEIN DEGRADATION; REGULATORY MECHANISM; TUMOR CELL; UBIQUITINATION; ALKYLATION; BIOLOGICAL MODEL; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; IMMUNOPRECIPITATION; METABOLISM; PHYSIOLOGY; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

ALKYLATION; BLOTTING, WESTERN; DIOXYGENASES; DNA DAMAGE; DNA REPAIR; DNA REPAIR ENZYMES; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; TANDEM MASS SPECTROMETRY; UBIQUITIN-SPECIFIC PROTEASES;

EID: 84931281713     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201490497     Document Type: Article

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