Wiskott-Aldrich syndrome iPS cells produce megakaryocytes with defects in cytoskeletal rearrangement and proplatelet formation

Thrombosis and Haemostasis

Volumn 113, Issue 4, 2015, Pages 792-805

  Ingrungruanglert, Praewphan ^a   Amarinthnukrowh, Pramuk ^a,b   Rungsiwiwut, Ruttachuk ^a   Maneesri le Grand, Supang ^a   Sosothikul, Darintr ^a   Suphapeetiporn, Kanya ^a,b   Israsena, Nipan ^a   Shotelersuk, Vorasuk ^a,b  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b KING CHULALONGKORN MEMORIAL HOSPITAL   (Thailand)

Author keywords

iPSCs; Platelet; Thrombopoiesis; WASP; Wiskott aldrich syndrome

Indexed keywords

CD34 ANTIGEN; F ACTIN; LENTIVIRUS VECTOR; WISKOTT ALDRICH SYNDROME PROTEIN; ACTIN; WAS PROTEIN, HUMAN;

ARTICLE; COLONY FORMING CELL; CONTROLLED STUDY; CYTOSKELETON; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MEGAKARYOCYTE; MUTATION; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROPLATELET; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBOCYTE; THROMBOCYTOPOIESIS; WESTERN BLOTTING; WISKOTT ALDRICH SYNDROME; BLOOD; CELL LINEAGE; CELL SHAPE; CELL SIZE; COCULTURE; FEEDER CELL; GENETIC PREDISPOSITION; GENETIC TRANSFECTION; GENETICS; MEGAKARYOBLAST; METABOLISM; PHENOTYPE; ULTRASTRUCTURE; WISKOTT-ALDRICH SYNDROME;

ACTINS; ANTIGENS, CD34; BLOOD PLATELETS; CELL LINEAGE; CELL SHAPE; CELL SIZE; COCULTURE TECHNIQUES; CYTOSKELETON; FEEDER CELLS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MEGAKARYOCYTE PROGENITOR CELLS; MEGAKARYOCYTES; MUTATION; PHENOTYPE; THROMBOPOIESIS; TRANSFECTION; WISKOTT-ALDRICH SYNDROME; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 84931281589     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH14-06-0503     Document Type: Article

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