Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes

Nature Communications

Volumn 6, Issue , 2015, Pages

  Palmer, Adam C ^a,c   Toprak, Erdal ^a,b   Baym, Michael ^a   Kim, Seungsoo ^a,d   Veres, Adrian ^a   Bershtein, Shimon ^c   Kishony, Roy ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; TRIMETHOPRIM;

ALLELE; ANTIBIOTIC RESISTANCE; ENZYME ACTIVITY; EVOLUTION; FITNESS; GENOTYPE; MUTATION;

ALLELE; ANTIBIOTIC RESISTANCE; ARTICLE; EPISTASIS; GENE INTERACTION; GENOTYPE; LANDSCAPE; MUTATION; NONHUMAN; EVOLUTION; GENETICS;

BIOLOGICAL EVOLUTION; DRUG RESISTANCE, MICROBIAL; EPISTASIS, GENETIC;

EID: 84931274969     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8385     Document Type: Article

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