Procoagulant platelets and the pathways leading to cell death

Seminars in Thrombosis and Hemostasis

Volumn 41, Issue 4, 2015, Pages 405-412

  Hua, Vu Minh ^a   Chen, Vivien Mun Yee ^a,b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b PRINCE OF WALES HOSPITAL   (Australia)

Author keywords

apoptosis; necrosis; platelet; procoagulant

Indexed keywords

ANTICOAGULANT AGENT; CASPASE INHIBITOR; CYCLOPHILIN D; CYCLOSPORIN A; FIBRINOGEN RECEPTOR; PROCOAGULANT; THROMBIN;

APOPTOSIS; ARTERY THROMBOSIS; ARTICLE; BLOOD CLOTTING; CELL DEATH; CELL HETEROGENEITY; CELL POPULATION; CELL SURVIVAL; HEMOSTASIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE LIFESPAN; THROMBOSIS; ANIMAL; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; THROMBOCYTE;

ANIMALS; BLOOD COAGULATION; BLOOD PLATELETS; CELL DEATH; HUMANS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; SIGNAL TRANSDUCTION; THROMBIN; THROMBOSIS;

EID: 84931268864     PISSN: 00946176     EISSN: 10989064     Source Type: Journal    
DOI: 10.1055/s-0034-1544002     Document Type: Article

References (58)

1. Jackson S. P. The growing complexity of platelet aggregation. Blood: 2007; 109 12 5087 5095
2. Nieswandt B., Pleines I., Bender M. Platelet adhesion and activation mechanisms in arterial thrombosis and ischaemic stroke. J Thromb Haemost: 2011; 9 01 92 104
3. Monroe D. M., Hoffman M. What does it take to make the perfect clot? Arterioscler Thromb Vasc Biol: 2006; 26 1 41 48
4. Alberio L., Safa O., Clemetson K. J., Esmon C. T., Dale G. L. Surface expression and functional characterization of alpha-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin. Blood: 2000; 95 5 1694 1702
5. Kempton C. L., Hoffman M., Roberts H. R., Monroe D. M. Platelet heterogeneity: variation in coagulation complexes on platelet subpopulations. Arterioscler Thromb Vasc Biol: 2005; 25 4 861 866
6. Ariëns R. A., Lai T. S., Weisel J. W., Greenberg C. S., Grant P. J. Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms. Blood: 2002; 100 3 743 754
7. Hoffman M., Monroe D. M. III. A cell-based model of hemostasis. Thromb Haemost: 2001; 85 6 958 965
8. Yang H., Kim A., David T., et al. TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell: 2012; 151 1 111 122
9. Suzuki J., Umeda M., Sims P. J., Nagata S. Calcium-dependent phospholipid scrambling by TMEM16F. Nature: 2010; 468 7325 834 838
10. Toti F., Satta N., Fressinaud E., Meyer D., Freyssinet J. M. Scott syndrome, characterized by impaired transmembrane migration of procoagulant phosphatidylserine and hemorrhagic complications, is an inherited disorder. Blood: 1996; 87 4 1409 1415
11. van Kruchten R., Mattheij N. JA, Saunders C., et al. Both TMEM16F-dependent and TMEM16F-independent pathways contribute to phosphatidylserine exposure in platelet apoptosis and platelet activation. Blood: 2013; 121 10 1850 1857
12. Jackson S. P. Arterial thrombosis--insidious, unpredictable and deadly. Nat Med: 2011; 17 11 1423 1436
13. Kirkpatrick A. C., Stoner J. A., Dale G. L., Prodan C. I. Elevated coated-platelets in symptomatic large-artery stenosis patients are associated with early stroke recurrence. Platelets: 2014; 25 2 93 96
14. Collaboration A. T. Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ: 2002; 324 7329 71 86
15. Dale G. L., Friese P., Batar P., et al. Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface. Nature: 2002; 415 6868 175 179
16. Yakimenko A. O., Verholomova F. Y., Kotova Y. N., Ataullakhanov F. I., Panteleev M. A. Identification of different proaggregatory abilities of activated platelet subpopulations. Biophys J: 2012; 102 10 2261 2269
17. Topalov N. N., Yakimenko A. O., Canault M., et al. Two types of procoagulant platelets are formed upon physiological activation and are controlled by integrin α(IIb)β(3). Arterioscler Thromb Vasc Biol: 2012; 32 10 2475 2483
18. Bevers E. M., Comfurius P., van Rijn J. LML, Hemker H. C., Zwaal R. F. Generation of prothrombin-converting activity and the exposure of phosphatidylserine at the outer surface of platelets. Eur J Biochem: 1982; 122 2 429 436
19. Jobe S. M., Wilson K. M., Leo L., et al. Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis. Blood: 2008; 111 3 1257 1265
20. Fager A. M., Wood J. P., Bouchard B. A., Feng P., Tracy P. B. Properties of procoagulant platelets: defining and characterizing the subpopulation binding a functional prothrombinase. Arterioscler Thromb Vasc Biol: 2010; 30 12 2400 2407
21. Munnix I. CA, Kuijpers M. JE, Auger J., et al. Segregation of platelet aggregatory and procoagulant microdomains in thrombus formation: regulation by transient integrin activation. Arterioscler Thromb Vasc Biol: 2007; 27 11 2484 2490
22. Heemskerk J. W., Vuist W. M., Feijge M. A., Reutelingsperger C. P., Lindhout T. Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine, and procoagulant activity of adherent platelets: evidence for regulation by protein tyrosine kinase-dependent Ca2+ responses. Blood: 1997; 90 7 2615 2625
23. Kulkarni S., Jackson S. P. Platelet factor XIII and calpain negatively regulate integrin alphaIIbbeta3 adhesive function and thrombus growth. J Biol Chem: 2004; 279 29 30697 30706
24. Mattheij N. JA, Gilio K., van Kruchten R., et al. Dual mechanism of integrin αIIbβ3 closure in procoagulant platelets. J Biol Chem: 2013; 288 19 13325 13336
25. Nesbitt W. S., Westein E., Tovar-Lopez F. J., et al. A shear gradient-dependent platelet aggregation mechanism drives thrombus formation. Nat Med: 2009; 15 6 665 673
26. Munnix I. C., Cosemans J. M., Auger J. M., Heemskerk J. W. Platelet response heterogeneity in thrombus formation. Thromb Haemost: 2009; 102 6 1149 1156
27. von Brühl M. L., Stark K., Steinhart A., et al. Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. J Exp Med: 2012; 209 4 819 835
28. Voronov R. S., Stalker T. J., Brass L. F., Diamond S. L. Simulation of intrathrombus fluid and solute transport using in vivo clot structures with single platelet resolution. Ann Biomed Eng: 2013; 41 6 1297 1307
29. Furihata K., Clemetson K. J., Deguchi H., Kunicki T. J. Variation in human platelet glycoprotein VI content modulates glycoprotein VI-specific prothrombinase activity. Arterioscler Thromb Vasc Biol: 2001; 21 11 1857 1863
30. Pasquet J. M., Toti F., Nurden A. T., Dachary-Prigent J. Procoagulant activity and active calpain in platelet-derived microparticles. Thromb Res: 1996; 82 6 509 522
31. Smeets E. F., Heemskerk J. W., Comfurius P., Bevers E. M., Zwaal R. F. Thapsigargin amplifies the platelet procoagulant response caused by thrombin. Thromb Haemost: 1993; 70 6 1024 1029
32. Thiagarajan P., Tait J. F. Collagen-induced exposure of anionic phospholipid in platelets and platelet-derived microparticles. J Biol Chem: 1991; 266 36 24302 24307
33. London F. S., Marcinkiewicz M., Walsh P. N. A subpopulation of platelets responds to thrombin- or SFLLRN-stimulation with binding sites for factor IXa. J Biol Chem: 2004; 279 19 19854 19859
34. Butenas S., van't Veer C., Mann K. G. Normal thrombin generation. Blood: 1999; 94 7 2169 2178
35. Remenyi G., Szasz R., Friese P., Dale G. L. Role of mitochondrial permeability transition pore in coated-platelet formation. Arterioscler Thromb Vasc Biol: 2005; 25 2 467 471
36. Leytin V., Allen D. J., Mutlu A., Gyulkhandanyan A. V., Mykhaylov S., Freedman J. Mitochondrial control of platelet apoptosis: effect of cyclosporin A, an inhibitor of the mitochondrial permeability transition pore. Lab Invest: 2009; 89 4 374 384
37. Batar P., Dale G. L. Simultaneous engagement of thrombin and Fc γ RIIA receptors results in platelets expressing high levels of procoagulant proteins. J Lab Clin Med: 2001; 138 6 393 402
38. Heemskerk J. W., Bevers E. M., Lindhout T. Platelet activation and blood coagulation. Thromb Haemost: 2002; 88 2 186 193
39. Feng P., Tracy P. B. Not all platelets are equivalent procoagulants. Blood: 1998; 92 1441a
40. Kuijpers M. JE, Schulte V., Oury C., et al. Facilitating roles of murine platelet glycoprotein Ib and alphaIIbbeta3 in phosphatidylserine exposure during vWF-collagen-induced thrombus formation. J Physiol: 2004; 558 Pt 2 403 415
41. Prodan C. I., Stoner J. A., Cowan L. D., Dale G. L. Higher coated-platelet levels are associated with stroke recurrence following nonlacunar brain infarction. J Cereb Blood Flow Metab: 2013; 33 2 287 292
42. Brown S. B., Clarke M. C., Magowan L., Sanderson H., Savill J. Constitutive death of platelets leading to scavenger receptor-mediated phagocytosis. A caspase-independent cell clearance program. J Biol Chem: 2000; 275 8 5987 5996
43. Kile B. T. The role of apoptosis in megakaryocytes and platelets. Br J Haematol: 2014; 165 2 217 226
44. White M. J., Schoenwaelder S. M., Josefsson E. C., et al. Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function. Blood: 2012; 119 18 4283 4290
45. Mason K. D., Carpinelli M. R., Fletcher J. I., et al. Programmed anuclear cell death delimits platelet life span. Cell: 2007; 128 6 1173 1186
46. Schoenwaelder S. M., Jackson S. P. Bcl-xL-inhibitory BH3 mimetics (ABT-737 or ABT-263) and the modulation of cytosolic calcium flux and platelet function. Blood: 2012; 119 5 1320 1321, author reply 1321-1322
47. Josefsson E. C., White M. J., Dowling M. R., Kile B. T. Platelet life span and apoptosis. Methods Mol Biol: 2012; 788 59 71
48. Leytin V., Allen D. J., Mykhaylov S., Lyubimov E., Freedman J. Thrombin-triggered platelet apoptosis. J Thromb Haemost: 2006; 4 12 2656 2663
49. Li S., Wang Z., Liao Y., et al. The glycoprotein Ibalpha-von Willebrand factor interaction induces platelet apoptosis. J Thromb Haemost: 2010; 8 2 341 350
50. Arachiche A., Kerbiriou-Nabias D., Garcin I., Letellier T., Dachary-Prigent J. Rapid procoagulant phosphatidylserine exposure relies on high cytosolic calcium rather than on mitochondrial depolarization. Arterioscler Thromb Vasc Biol: 2009; 29 11 1883 1889
51. Schoenwaelder S. M., Yuan Y., Josefsson E. C., et al. Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function. Blood: 2009; 114 3 663 666
52. Schoenwaelder S. M., Jarman K. E., Gardiner E. E., et al. Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets. Blood: 2011; 118 6 1663 1674
53. Festjens N., Vanden Berghe T., Vandenabeele P. Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. Biochim Biophys Acta: 2006; 1757 9-10 1371 1387
54. Zong W. X., Thompson C. B. Necrotic death as a cell fate. Genes Dev: 2006; 20 1 1 15
55. Nakagawa T., Shimizu S., Watanabe T., et al. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature: 2005; 434 7033 652 658
56. Choo H-J, Saafir T. B., Mkumba L., Wagner M. B., Jobe S. M. Mitochondrial calcium and reactive oxygen species regulate agonist-initiated platelet phosphatidylserine exposure. Arterioscler Thromb Vasc Biol: 2012; 32 12 2946 2955
57. Reményi G., Szász R., Debreceni I. B., et al. Comparison of coated-platelet levels in patients with essential thrombocythemia with and without hydroxyurea treatment. Platelets: 2013; 24 6 486 492
58. Prodan C. I., Vincent A. S., Dale G. L. Coated-platelet levels are elevated in patients with transient ischemic attack. Transl Res: 2011; 158 1 71 75