Variation in human platelet glycoprotein VI content modulates glycoprotein VI-specific prothrombinase activity

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 21, Issue 11, 2001, Pages 1857-1863

  Furihata, Kenichi ^a   Clemetson, Kenneth J ^a   Deguchi, Hiroshi ^a   Kunicki, Thomas J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Glycoprotein VI; Platelets; Polymorphism; Prothrombinase; 2 1 complex

Indexed keywords

BLOOD CLOTTING FACTOR 10A; CD36 ANTIGEN; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CONVULXIN; GLYCOPROTEIN; SNAKE VENOM;

ARTICLE; BINDING AFFINITY; BLOOD CLOTTING; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; PRIORITY JOURNAL; RISK FACTOR; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOEMBOLISM;

EID: 0035571593     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/hq1001.096643     Document Type: Article

References (29)

1. 1 activity on human platelets
2. 2 gene coding sequence
3. 1 density
4. Association of the platelet glycoprotein Ia C807T gene polymorphism with nonfatal myocardial infarction in younger patients
5. 1 might be a genetic risk factor for the development of stroke in younger patients
6. 1 levels in type I von Willebrand disease correlate with impaired platelet function in a high shear stress system
7. Platelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake) venom via the p62/GPVI collagen receptor
8. 1
9. Collagen-platelet interaction: Gly-Pro-Hyp is uniquely specific for platelet Gp VI and mediates platelet activation by collagen
10. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
11. Surface expression and functional characterization of alpha-granule factor V in human platelets: Effects of ionophore A23187, thrombin, collagen, and convulxin
12. A colorimetric method for the measurement of platelet adhesion in microtiter plates
13. The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcαR and the natural killer receptors
14. Functional characterization of human platelet-released factor V and its activation by factor Xa and thrombin
15. Update on collagen receptor interactions in platelets: Is the two-state model still valid?
16. Molecular cloning, genomic structure, chromosomal localization, and alternative splice forms of the platelet collagen receptor glycoprotein VI
17. Cloning, characterization, and functional studies of human and mouse glycoprotein VI: A platelet-specific collagen receptor from the immunoglobulin superfamily
18. A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia
19. The Fc receptor γ-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen
20. Expression and function of the mouse collagen receptor GPVI is strictly dependent on its association with the FcR γ-chain
21. Ineffective platelet production in thrombocytopenic human immunodeficiency virus-infected patients
22. Bernard-Soulier syndrome: Quantitative characterization of megakaryocytes and platelets by flow cytometric and platelet kinetic measurements
23. Fibrin contributes to microvascular obstructions and parenchymal changes during early focal cerebral ischemia and reperfusion
24. Effects of tissue factor induced by oxygen free radicals on coronary flow during reperfusion
25. Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease
26. Platelet adhesion enhances the glycoprotein VI-dependent procoagulant response: Involvement of p38 MAP kinase and calpain
27. Response of human platelets to activating monoclonal antibodies: Importance of FcγRII (CD32) phenotype and level of expression
28. Human Fcγ receptors: Stable inter-donor variation in quantitative expression on platelets correlates with functional responses
29. Physical proximity and functional interplay of the glycoprotein Ib-IX-V complex and the Fc receptor FcγRIIA on the platelet plasma membrane