Thermosensitive dendritic polyglycerol-based nanogels for cutaneous delivery of biomacromolecules

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 11, Issue 5, 2015, Pages 1179-1187

  Witting, Madeleine ^a   Molina, Maria ^b   Obst, Katja ^b   Plank, Roswitha ^c,d   Eckl, Katja Martina ^c   Hennies, Hans Christian ^c,d,e   Calderón, Marcelo ^b   Frieß, Wolfgang ^a   Hedtrich, Sarah ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d UNIVERSITY OF COLOGNE   (Germany)

^e UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Cutaneous protein delivery; Dendritic polyglycerol; Reconstructed human skin; Skin barrier restoration; Thermoresponsive nanogels

Indexed keywords

ACRYLIC MONOMERS; AMIDES; GENES; NANOSTRUCTURED MATERIALS; PARTICLE SIZE; PHYSICOCHEMICAL PROPERTIES; PLANTS (BOTANY); PROTEINS; RESTORATION;

CUTANEOUS DELIVERIES; HUMAN SKIN; NANOGELS; POLY (N ISOPROPYLACRYLAMIDE); POLYGLYCEROLS; PROTEIN DELIVERY; SKIN BARRIER FUNCTIONS; TOPICAL APPLICATION;

BIOSYNTHESIS;

ASPARAGINASE; BOVINE SERUM ALBUMIN; FLUORESCENT DYE; GLYCEROL DERIVATIVE; NANOCARRIER; NANOGEL; POLY(N ISOPROPYLACRYLAMIDE)POLYGLYCEROL; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; TRANSGLUTAMINASE 1; UNCLASSIFIED DRUG; ACRYLIC ACID RESIN; DELAYED RELEASE FORMULATION; GEL; GLYCEROL; POLY-N-ISOPROPYLACRYLAMIDE; POLYGLYCEROL; POLYMER; TESTOSTERONE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; NANOENCAPSULATION; NANOFABRICATION; NONHUMAN; PARTICLE SIZE; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SKIN PENETRATION; TOPICAL TREATMENT; TRIGGER POINT; ANIMAL; BOVINE; CHEMISTRY; DELAYED RELEASE FORMULATION; GEL; GENE SILENCING; GENETICS; HUMAN; INTRADERMAL DRUG ADMINISTRATION; METABOLISM; PIG; SKIN; SKIN ABSORPTION; TEMPERATURE; ULTRASTRUCTURE;

ACRYLIC RESINS; ADMINISTRATION, CUTANEOUS; ANIMALS; ASPARAGINASE; CATTLE; DELAYED-ACTION PREPARATIONS; GELS; GENE KNOCKDOWN TECHNIQUES; GLYCEROL; HUMANS; POLYMERS; SERUM ALBUMIN, BOVINE; SKIN; SKIN ABSORPTION; SWINE; TEMPERATURE; TESTOSTERONE; TRANSGLUTAMINASES;

EID: 84931086766     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2015.02.017     Document Type: Article

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