Lentinula edodes-derived polysaccharide enhances systemic and mucosal immunity by spatial modulation of intestinal gene expression in mice

Food and Function

Volumn 6, Issue 6, 2015, Pages 2068-2080

  Xu, Xiaofei ^a,b   Yang, Jiguo ^a   Luo, Zhen ^a   Zhang, Xuewu ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

^b Treerly Women's Nutrition and Health Institute   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALS;

CO-CULTURE SYSTEM; HETEROPOLYSACCHARIDE; IMMUNO-STIMULATING ACTIVITIES; MOLECULAR MECHANISM; MUSHROOM POLYSACCHARIDES; REGULATION NETWORKS; SPATIAL MODULATIONS; TISSUE-SPECIFIC GENE EXPRESSION;

GENE EXPRESSION;

BASIDIOMYCOTA; LENTINULA EDODES; MUS;

CARBOHYDRATE DIET; CYTOKINE; FUNGAL POLYSACCHARIDE;

ANALYSIS; ANIMAL; BLOOD; C57BL MOUSE; CACO 2 CELL LINE; CARBOHYDRATE DIET; CELL LINE RAW 264.7; CHEMISTRY; COCULTURE; FRUITING BODY; FUNCTIONAL FOOD; GENE EXPRESSION REGULATION; GERMFREE ANIMAL; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; INTESTINE; INTESTINE CELL; INTESTINE MUCOSA; LENTINULA EDODES; MACROPHAGE; MALE; METABOLISM; MOUSE; MUCOSAL IMMUNITY; SECRETION (PROCESS);

ANIMALS; CACO-2 CELLS; COCULTURE TECHNIQUES; CYTOKINES; DIETARY CARBOHYDRATES; ENTEROCYTES; FRUITING BODIES, FUNGAL; FUNCTIONAL FOOD; FUNGAL POLYSACCHARIDES; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; IMMUNITY, MUCOSAL; INTESTINAL MUCOSA; INTESTINES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; RAW 264.7 CELLS; SHIITAKE MUSHROOMS; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 84931078701     PISSN: 20426496     EISSN: 2042650X     Source Type: Journal    
DOI: 10.1039/c4fo01192a     Document Type: Article

References (45)

1. J. A. Bohn J. N. BeMiller (1→3)-β-D-Glucans as biological response modifiers: a review of structure-functional activity relationships Carbohydr. Polym. 1995 28 3 14
2. B. Kournikakis R. Mandeville P. Brousseau G. Ostroff Anthrax-protective effects of yeast beta 1,3 glucans MedGenMed 2003 5 1 1
3. J. Herre J. A. Willment S. Gordon G. D. Brown The role of Dectin-1 in antifungal immunity Crit. Rev. Immunol. 2004 24 3 193 203
4. J. Chen R. Seviour Medicinal importance of fungal beta-(1->3), (1->6)-glucans Mycol. Res. 2007 111 Pt 6 635 652
5. E. A. Murphy J. M. Davis M. D. Carmichael Immune modulating effects of β-glucan Curr. Opin. Clin. Nutr. Metab. Care 2010 13 6 656 661
6. S. H. Albeituni J. Yan The effects of β-glucans on dendritic cells and implications for cancer therapy Anticancer Agents Med. Chem. 2013 13 5 689 698
7. R. Nicolosi S. J. Bell B. R. Bistrian I. Greenberg et al., Plasma lipid changes after supplementation with beta-glucan fiber from yeast Am. J. Clin. Nutr. 1999 70 2 208 212
8. H. C. Lo F. A. Tsai S. P. Wasser J. G. Yang et al., Effects of ingested fruiting bodies, submerged culture biomass, and acidic polysaccharide glucuronoxylomannan of Tremella mesenterica Retz.:Fr. on glycemic responses in normal and diabetic rats Life Sci. 2006 78 17 1957 1966
9. S. P. Wasser Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides Appl. Microbiol. Biotechnol. 2002 60 258 274
10. P. S. Bisen R. K. Baghel B. S. Sanodiya G. S. Thakur et al., Lentinus edodes: A Macrofungus with Pharmacological Activities Curr. Med. Chem. 2010 22 2419 2430
11. G. Chihara J. Hamuro Y. Y. Maeda Y. Arai et al., Fractionation and purification of the polysaccharides with marked antitumor activity, especially lentinan, from Lentinus edodes (Berk.) Sing. (an edible mushroom) Cancer Res. 1970 30 2776 2781
12. Y. Y. Zhang S. Li X. H. Wang L. N. Zhang et al., Advances in Lentinan: Isolation, structure, chain conformation and bioactivities Food Hydrocolloids 2011 25 2 196 206
13. P. M. Kidd The use of mushroom glucans and proteoglycans in cancer treatment Altern. Med. Rev. 2000 5 1 4 27
14. E. R. Carbonero A. H. P. Gracher D. L. Komura R. Marcon et al., Lentinus edodes heterogalactan: Antinociceptive and anti-inflammatory effects Food Chem. 2008 111 531 537
15. H. Fu W. Y. Guo H. Yin Z. X. Wang et al., Inhibition of Lentinus edodes polysaccharides against liver tumour growth Int. J. Phys. Sci. 2011 6 1 116 120
16. X. F. Xu H. D. Yan X. W. Zhang Structure and Immuno-Stimulating Activities of a New Heteropolysaccharide from Lentinula edodes J. Agric. Food Chem. 2012 60 46 11560 11566
17. L. Zhang X. Li X. Xu F. Zeng Correlation between antitumor activity, molecular weight, and conformation of lentinan Carbohydr. Res. 2005 340 8 1515 1521
18. X. Xu X. Zhang Lentinula edodes-derived polysaccharide alters the spatial structure of gut microbiota in mice PLoS One 2015 10 1 e0115037
19. E. Larsson V. Tremaroli Y. S. Lee O. Koren et al., Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88 Gut 2012 61 8 1124 1131
20. H. Yuan J. Song X. Li N. Li et al., Immunomodulation and antitumor activity of kappa-carrageenan oligosaccharides Cancer Lett. 2006 243 2 228 234
21. H. Wang M. Wang J. Chen Y. Tang et al., A polysaccharide from Strongylocentrotus nudus eggs protects against myelosuppression and immunosuppression in cyclophosphamide-treated mice Int. Immunopharmacol. 2011 11 11 1946 1953
22. J. Wang X. Tong P. Li H. Cao et al., Immuno-enhancement effects of Shenqi Fuzheng Injection on cyclophosphamide-induced immunosuppression in Balb/c mice J. Ethnopharmacol. 2012 139 3 788 795
23. A. V. Antonov E. Schmidt S. Dietmann M. Krestyaninova et al., R spider: a network-based analysis of gene lists by combining signaling and metabolic pathways from Reactome and KEGG databases Nucleic Acids Res. 2010 38 suppl-2 W118 W123
24. H. J. Flint K. P. Scott P. Louis S. H. Duncan The role of the gut microbiota in nutrition and health Nat. Rev. Gastroenterol. Hepatol. 2012 9 10 577 589
25. H. S. Goodridge A. J. Wolf D. M. Underhill Beta-glucan recognition by the innate immune system Immunol. Rev. 2009 230 1 38 50
26. S. Li M. Gallup Y. T. Chen N. A. McNamara Molecular mechanism of proinflammatory cytokine-mediated squamous metaplasia in human corneal epithelial cells Invest. Ophthalmol. Vis. Sci. 2010 51 5 2466 2475
27. H. Kawashima Roles of the gel-forming MUC2 mucin and its O-glycosylation in the protection against colitis and colorectal cancer Biol. Pharm. Bull. 2012 35 10 1637 1641
28. A. Finnegan M. J. Grusby C. D. Kaplan S. K. O'Neill et al., IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms J. Immunol. 2002 169 6 3345 3352
29. K. Kamezaki K. Shimoda A. Numata T. Matsuda et al., The role of Tyk2, Stat1 and Stat4 in LPS-induced endotoxin signals Int. Immunol. 2004 16 8 1173 1179
30. A. W. Yan D. E. Fouts J. Brandl P. Stärkel et al., Enteric dysbiosis associated with a mouse model of alcoholic liver disease Hepatology 2011 53 1 96 105
31. I. Amelio M. Gostev R. A. Knight A. E. Willis et al., DRUGSURV: a resource for repositioning of approved and experimental drugs in oncology based on patient survival information Cell. Death. Dis. 2014 5 e1051
32. J. Hou J. Aerts B. den Hamer W. van Ijcken et al., Gene expression-based classification of non-small cell lung carcinomas and survival prediction PLoS One 2010 5 4 e10312
33. Y. Pawitan J. Bjöhle L. Amler A. L. Borg et al., Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts Breast Cancer Res. Treat. 2005 7 6 R953 R964
34. Z. Hu C. Fan C. Livasy X. He et al., A compact VEGF signature associated with distant metastases and poor outcomes BMC Med. 2009 7 9
35. S. Pradervand H. Yasukawa O. G. Muller H. Kjekshus et al., Small proline-rich protein 1A is a gp130 pathway- and stress-inducible cardioprotective protein EMBO J. 2004 23 22 4517 4525
36. Y. Kim S. H. Kim K. Y. Whang Y. J. Kim et al., Inhibition of Escherichia coli O157:H7 attachment by interactions between lactic acid bacteria and intestinal epithelial cells J. Microbiol. Biotechnol. 2008 18 7 1278 1285
37. R. Prakash S. Bharathi Raja H. Devaraj S. N. Devaraj Up-regulation of MUC2 and IL-1β expression in human colonic epithelial cells by Shigella and its interaction with mucins PLoS One 2011 6 11 e27046
38. R. C. Rickert J. Jellusova A. V. Miletic Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease Immunol. Rev. 2011 244 1 115 133
39. K. Warnatz U. Salzer M. Rizzi B. Fischer et al., B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans Proc. Natl. Acad. Sci. U. S. A. 2009 106 33 13945 13950
40. S. S. Kim D. P. Richman S. S. Zamvil M. A. Agius Accelerated central nervous system autoimmunity in BAFF-receptor-deficient mice J. Neurol. Sci. 2011 306 1-2 9 15
41. I. Moisini A. Davidson BAFF: a local and systemic target in autoimmune diseases Clin. Exp. Immunol. 2009 158 2 155 163
42. S. T. Jeon W. J. Kim S. M. Lee M. Y. Lee et al., Reverse signaling through BAFF differentially regulates the expression of inflammatory mediators and cytoskeletal movements in THP-1 cells Immunol. Cell. Biol. 2010 88 2 148 156
43. S. M. Lee E. J. Kim K. Suk W. H. Lee BAFF and APRIL induce inflammatory activation of THP-1 cells through interaction with their conventional receptors and activation of MAPK and NF-κB Inflammation Res. 2011 60 9 807 815
44. A. P. Sage D. Tsiantoulas L. Baker J. Harrison et al., BAFF receptor deficiency reduces the development of atherosclerosis in mice-brief report Arterioscler., Thromb., Vasc. Biol. 2012 32 7 1573 1576
45. A. Gewirtz Gut microbiota, low-grade inflammation, and metabolic syndrome FASEB J. 2015 29 1 suppl. 368.2