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Volumn 51, Issue 5, 2010, Pages 2466-2475

Molecular mechanism of proinflammatory Cytokine-mediated squamous metaplasia in human corneal epithelial cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GAMMA INTERFERON; HOMEODOMAIN PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ZINC FINGER E BOX BINDING HOMEOBOX 1 PROTEIN; BIOLOGICAL MARKER; CORNIFIED ENVELOPE LIKE PROLINE RICH PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; SPRR1B PROTEIN, HUMAN; TRANSCRIPTION FACTOR; VIRUS T ANTIGEN; ZEB1 PROTEIN, HUMAN;

EID: 77952519493     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4677     Document Type: Article
Times cited : (55)

References (59)
  • 1
    • 0014871421 scopus 로고
    • The induction of keratinization in the corneal epithelium: A comparison of the "dry" and vitamin A-deficient eyes
    • Beitch I. The induction of keratinization in the corneal epithelium: a comparison of the "dry" and vitamin A-deficient eyes. Invest Ophthalmol. 1970;9:827-843.
    • (1970) Invest Ophthalmol. , vol.9 , pp. 827-843
    • Beitch, I.1
  • 2
    • 0021023032 scopus 로고
    • Cellulose acetate impressions of the ocular surface: Dry eye states
    • Nelson JD, Havener VR, Cameron JD. Cellulose acetate impressions of the ocular surface: dry eye states. Arch Ophthalmol. 1983;101:1869-1872.
    • (1983) Arch Ophthalmol. , vol.101 , pp. 1869-1872
    • Nelson, J.D.1    Havener, V.R.2    Cameron, J.D.3
  • 3
    • 0021795877 scopus 로고
    • Staging of conjunctival squamous metaplasia by impression cytology
    • Tseng SC. Staging of conjunctival squamous metaplasia by impression cytology. Ophthalmology. 1985;92:728-733.
    • (1985) Ophthalmology. , vol.92 , pp. 728-733
    • Tseng, S.C.1
  • 4
    • 0031744588 scopus 로고    scopus 로고
    • Alterations of ocular surface gene expression in Sjögren's syndrome
    • Jones DT, Monroy D, Ji Z, Pflugfelder SC. Alterations of ocular surface gene expression in Sjögren's syndrome. Adv Exp Med Biol. 1998;438:533-536.
    • (1998) Adv Exp Med Biol. , vol.438 , pp. 533-536
    • Jones, D.T.1    Monroy, D.2    Ji, Z.3    Pflugfelder, S.C.4
  • 5
    • 39549090013 scopus 로고    scopus 로고
    • Air exposure induced squamous metaplasia of human limbal epithelium
    • Li W, Hayashida Y, Chen YT, et al. Air exposure induced squamous metaplasia of human limbal epithelium. Invest Ophthalmol Vis Sci. 2008;49:154-162.
    • (2008) Invest Ophthalmol Vis Sci. , vol.49 , pp. 154-162
    • Li, W.1    Hayashida, Y.2    Chen, Y.T.3
  • 6
    • 33646034079 scopus 로고    scopus 로고
    • Desiccating stress induces T cell-mediated Sjögren's syndrome-like lacrimal keratoconjunctivitis
    • Niederkorn JY, Stern ME, Pflugfelder SC, et al. Desiccating stress induces T cell-mediated Sjögren's syndrome-like lacrimal keratoconjunctivitis. J Immunol. 2006;176:3950-3957.
    • (2006) J Immunol. , vol.176 , pp. 3950-3957
    • Niederkorn, J.Y.1    Stern, M.E.2    Pflugfelder, S.C.3
  • 7
    • 0036327292 scopus 로고    scopus 로고
    • Conjunctival T-cell subpopulations in Sjögren's and non-Sjögren's patients with dry eye
    • Stern ME, Gao J, Schwalb TA, et al. Conjunctival T-cell subpopulations in Sjögren's and non-Sjögren's patients with dry eye. Invest Ophthalmol Vis Sci. 2002;43:2609-2614.
    • (2002) Invest Ophthalmol Vis Sci. , vol.43 , pp. 2609-2614
    • Stern, M.E.1    Gao, J.2    Schwalb, T.A.3
  • 8
    • 34347233852 scopus 로고    scopus 로고
    • Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma
    • De Paiva CS, Villarreal AL, Corrales RM, et al. Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma. Invest Ophthalmol Vis Sci. 2007;48:2553-2560.
    • (2007) Invest Ophthalmol Vis Sci. , vol.48 , pp. 2553-2560
    • de Paiva, C.S.1    Villarreal, A.L.2    Corrales, R.M.3
  • 9
    • 0032602126 scopus 로고    scopus 로고
    • Expression, regulation, and function of the SPR family of proteins: A review
    • Tesfaigzi J, Carlson DM. Expression, regulation, and function of the SPR family of proteins: a review. Cell Biochem Biophys. 1999;30: 243-265.
    • (1999) Cell Biochem Biophys. , vol.30 , pp. 243-265
    • Tesfaigzi, J.1    Carlson, D.M.2
  • 10
    • 0028928292 scopus 로고
    • Tissue-specific expression of the fos-related transcription factor fra-2 during mouse development
    • Carrasco D, Bravo R. Tissue-specific expression of the fos-related transcription factor fra-2 during mouse development. Oncogene. 1995;10:1069-1079.
    • (1995) Oncogene. , vol.10 , pp. 1069-1079
    • Carrasco, D.1    Bravo, R.2
  • 11
    • 39549098201 scopus 로고    scopus 로고
    • Small proline-rich protein 1B (SPRR1B) is a biomarker for squamous metaplasia in dry eye disease
    • Li S, Nikulina K, DeVoss J, et al. Small proline-rich protein 1B (SPRR1B) is a biomarker for squamous metaplasia in dry eye disease. Invest Ophthalmol Vis Sci. 2008;49:34-41.
    • (2008) Invest Ophthalmol Vis Sci. , vol.49 , pp. 34-41
    • Li, S.1    Nikulina, K.2    DeVoss, J.3
  • 12
    • 38049071703 scopus 로고    scopus 로고
    • Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes
    • Demetris AJ, Specht S, Nozaki I, et al. Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes. J Hepatol. 2008;48:276-288.
    • (2008) J Hepatol. , vol.48 , pp. 276-288
    • Demetris, A.J.1    Specht, S.2    Nozaki, I.3
  • 13
    • 0038434060 scopus 로고    scopus 로고
    • Up-regulated gene expression in the conjunctival epithelium of patients with Sjögren's syndrome
    • Kawasaki S, Kawamoto S, Yokoi N, et al. Up-regulated gene expression in the conjunctival epithelium of patients with Sjögren's syndrome. Exp Eye Res. 2003;77:17-26.
    • (2003) Exp Eye Res. , vol.77 , pp. 17-26
    • Kawasaki, S.1    Kawamoto, S.2    Yokoi, N.3
  • 14
    • 65249093601 scopus 로고    scopus 로고
    • Immune profile of squamous metaplasia development in autoimmune regulator-deficient dry eye
    • Chen YT, Li S, Nikulina K, et al. Immune profile of squamous metaplasia development in autoimmune regulator-deficient dry eye. Mol Vis. 2009;15:563-576.
    • (2009) Mol Vis. , vol.15 , pp. 563-576
    • Chen, Y.T.1    Li, S.2    Nikulina, K.3
  • 15
    • 0034849206 scopus 로고    scopus 로고
    • Pro-and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease
    • Solomon A, Dursun D, Liu Z, et al. Pro-and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease. Invest Ophthalmol Vis Sci. 2001;42:2283-2292.
    • (2001) Invest Ophthalmol Vis Sci. , vol.42 , pp. 2283-2292
    • Solomon, A.1    Dursun, D.2    Liu, Z.3
  • 16
    • 0141653766 scopus 로고    scopus 로고
    • Neurturin-deficient mice develop dry eye and keratoconjunctivitis sicca
    • Song XJ, Li DQ, Farley W, et al. Neurturin-deficient mice develop dry eye and keratoconjunctivitis sicca. Invest Ophthalmol Vis Sci. 2003;44:4223-4229.
    • (2003) Invest Ophthalmol Vis Sci. , vol.44 , pp. 4223-4229
    • Song, X.J.1    Li, D.Q.2    Farley, W.3
  • 17
    • 0036940594 scopus 로고    scopus 로고
    • Experimentally induced dry eye produces ocular surface inflammation and epithelial disease
    • Dursun D, Wang M, Monroy D, et al. Experimentally induced dry eye produces ocular surface inflammation and epithelial disease. Adv Exp Med Biol. 2002;506:647-655.
    • (2002) Adv Exp Med Biol. , vol.506 , pp. 647-655
    • Dursun, D.1    Wang, M.2    Monroy, D.3
  • 18
    • 1842405942 scopus 로고    scopus 로고
    • Ultraviolet irradiation induces the production of multiple cytokines by human corneal cells
    • Kennedy M, Kim KH, Harten B, et al. Ultraviolet irradiation induces the production of multiple cytokines by human corneal cells. Invest Ophthalmol Vis Sci. 1997;38:2483-2491.
    • (1997) Invest Ophthalmol Vis Sci. , vol.38 , pp. 2483-2491
    • Kennedy, M.1    Kim, K.H.2    Harten, B.3
  • 19
    • 0026009299 scopus 로고
    • Human corneal interleukin-8: IL-1 and TNF-induced gene expression and secretion
    • Elner VM, Strieter RM, Pavilack MA, et al. Human corneal interleukin-8: IL-1 and TNF-induced gene expression and secretion. Am J Pathol. 1991;139:977-988.
    • (1991) Am J Pathol. , vol.139 , pp. 977-988
    • Elner, V.M.1    Strieter, R.M.2    Pavilack, M.A.3
  • 20
    • 0024661204 scopus 로고
    • Interferon-gamma, Staphylococcus aureus, and lipopolysaccharide/silica enhance interleukin-1 beta production by human corneal cells
    • Shams NB, Sigel MM, Davis RM. Interferon-gamma, Staphylococcus aureus, and lipopolysaccharide/silica enhance interleukin-1 beta production by human corneal cells. Reg Immunol. 1989;2:136-148.
    • (1989) Reg Immunol. , vol.2 , pp. 136-148
    • Shams, N.B.1    Sigel, M.M.2    Davis, R.M.3
  • 21
    • 49849088020 scopus 로고    scopus 로고
    • Interleukin-1 receptor-1-deficient mice show attenuated production of ocular surface inflammatory cytokines in experimental dry eye
    • Narayanan S, Corrales RM, Farley W, et al. Interleukin-1 receptor-1-deficient mice show attenuated production of ocular surface inflammatory cytokines in experimental dry eye. Cornea. 2008;27: 811-817.
    • (2008) Cornea. , vol.27 , pp. 811-817
    • Narayanan, S.1    Corrales, R.M.2    Farley, W.3
  • 22
    • 36048937539 scopus 로고    scopus 로고
    • Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients
    • Araya J, Cambier S, Markovics JA, et al. Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients. J Clin Invest. 2007;117:3551-3562.
    • (2007) J Clin Invest. , vol.117 , pp. 3551-3562
    • Araya, J.1    Cambier, S.2    Markovics, J.A.3
  • 23
    • 36849036400 scopus 로고    scopus 로고
    • Transcriptional responses of human epidermal keratinocytes to cytokine interleukin-1
    • Yano S, Banno T, Walsh R, Blumenberg M. Transcriptional responses of human epidermal keratinocytes to cytokine interleukin-1. J Cell Physiol. 2008;214:1-13.
    • (2008) J Cell Physiol. , vol.214 , pp. 1-13
    • Yano, S.1    Banno, T.2    Walsh, R.3    Blumenberg, M.4
  • 24
    • 0033810257 scopus 로고    scopus 로고
    • Conjunctival inflammation in the chronic phase of Stevens-Johnson syndrome
    • Kawasaki S, Nishida K, Sotozono C, et al. Conjunctival inflammation in the chronic phase of Stevens-Johnson syndrome. Br J Ophthalmol. 2000;84:1191-1193.
    • (2000) Br J Ophthalmol. , vol.84 , pp. 1191-1193
    • Kawasaki, S.1    Nishida, K.2    Sotozono, C.3
  • 25
    • 0033572653 scopus 로고    scopus 로고
    • Interferon-gamma-dependent stimulation of human involucrin gene expression: STAT1 (signal transduction and activators of transcription 1) protein activates involucrin promoter activity
    • Takahashi H, Asano K, Nakamura S, et al. Interferon-gamma-dependent stimulation of human involucrin gene expression: STAT1 (signal transduction and activators of transcription 1) protein activates involucrin promoter activity. Biochem J. 1999;344(pt 3): 797-802.
    • (1999) Biochem J. , vol.344 , Issue.PART 3 , pp. 797-802
    • Takahashi, H.1    Asano, K.2    Nakamura, S.3
  • 26
    • 31344473767 scopus 로고    scopus 로고
    • Pathological keratinisation in the conjunctival epithelium of Sjögren's syndrome
    • Hirai N, Kawasaki S, Tanioka H, et al. Pathological keratinisation in the conjunctival epithelium of Sjögren's syndrome. Exp Eye Res. 2006;82:371-378.
    • (2006) Exp Eye Res. , vol.82 , pp. 371-378
    • Hirai, N.1    Kawasaki, S.2    Tanioka, H.3
  • 27
    • 0345708054 scopus 로고    scopus 로고
    • Complex redundancy to build a simple epidermal permeability barrier
    • Segre J. Complex redundancy to build a simple epidermal permeability barrier. Curr Opin Cell Biol. 2003;15:776-782.
    • (2003) Curr Opin Cell Biol. , vol.15 , pp. 776-782
    • Segre, J.1
  • 28
    • 34547857779 scopus 로고    scopus 로고
    • Human amniotic epithelial cells as novel feeder layers for promoting ex vivo expansion of limbal epithelial progenitor cells
    • Chen YT, Li W, Hayashida Y, et al. Human amniotic epithelial cells as novel feeder layers for promoting ex vivo expansion of limbal epithelial progenitor cells. Stem Cells. 2007;25:1995-2005.
    • (2007) Stem Cells. , vol.25 , pp. 1995-2005
    • Chen, Y.T.1    Li, W.2    Hayashida, Y.3
  • 29
    • 0030898417 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways
    • Robinson MJ, Cobb MH. Mitogen-activated protein kinase pathways. Curr Opin Cell Biol. 1997;9:180-186.
    • (1997) Curr Opin Cell Biol. , vol.9 , pp. 180-186
    • Robinson, M.J.1    Cobb, M.H.2
  • 30
    • 0035896611 scopus 로고    scopus 로고
    • MEK7-dependent activation of p38 MAP kinase in keratinocytes
    • Dashti SR, Efimova T, Eckert RL. MEK7-dependent activation of p38 MAP kinase in keratinocytes. J Biol Chem. 2001;276:8059-8063.
    • (2001) J Biol Chem. , vol.276 , pp. 8059-8063
    • Dashti, S.R.1    Efimova, T.2    Eckert, R.L.3
  • 31
    • 0023819169 scopus 로고
    • Conjunctival biopsy in Sjögren's syndrome: Correlations between histological and immunohistochemical features
    • Raphael M, Bellefqih S, Piette JC, et al. Conjunctival biopsy in Sjögren's syndrome: correlations between histological and immunohistochemical features. Histopathology. 1988;13:191-202.
    • (1988) Histopathology. , vol.13 , pp. 191-202
    • Raphael, M.1    Bellefqih, S.2    Piette, J.C.3
  • 33
    • 0028172789 scopus 로고
    • Sjögren's syndrome: Cytokine and Epstein-Barr viral gene expression within the conjunctival epithelium
    • Jones DT, Monroy D, Ji Z, et al. Sjögren's syndrome: cytokine and Epstein-Barr viral gene expression within the conjunctival epithelium. Invest Ophthalmol Vis Sci. 1994;35:3493-3504.
    • (1994) Invest Ophthalmol Vis Sci. , vol.35 , pp. 3493-3504
    • Jones, D.T.1    Monroy, D.2    Ji, Z.3
  • 34
    • 0032709209 scopus 로고    scopus 로고
    • Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis sicca
    • Pflugfelder SC, Jones D, Ji Z, et al. Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis sicca. Curr Eye Res. 1999;19:201-211.
    • (1999) Curr Eye Res. , vol.19 , pp. 201-211
    • Pflugfelder, S.C.1    Jones, D.2    Ji, Z.3
  • 35
    • 28544442794 scopus 로고    scopus 로고
    • Gene expression profiling of Japanese psoriatic skin reveals an increased activity in molecular stress and immune response signals
    • Kulski JK, Kenworthy W, Bellgard M, et al. Gene expression profiling of Japanese psoriatic skin reveals an increased activity in molecular stress and immune response signals. J Mol Med. 2005; 83:964-975.
    • (2005) J Mol Med. , vol.83 , pp. 964-975
    • Kulski, J.K.1    Kenworthy, W.2    Bellgard, M.3
  • 36
    • 0025000749 scopus 로고
    • Immunopathology of cicatricial pemphigoid affecting the conjunctiva
    • Rice BA, Foster CS. Immunopathology of cicatricial pemphigoid affecting the conjunctiva. Ophthalmology. 1990;97:1476-1483.
    • (1990) Ophthalmology. , vol.97 , pp. 1476-1483
    • Rice, B.A.1    Foster, C.S.2
  • 37
    • 84949117839 scopus 로고    scopus 로고
    • Evaluation of ocular surface inflammation in the presence of dry eye and allergic conjunctival disease
    • Stern ME, Siemasko KF, Gao J, et al. Evaluation of ocular surface inflammation in the presence of dry eye and allergic conjunctival disease. Ocul Surf. 2005;3:S161-S164.
    • (2005) Ocul Surf. , vol.3
    • Stern, M.E.1    Siemasko, K.F.2    Gao, J.3
  • 38
    • 0030605404 scopus 로고    scopus 로고
    • Interleukin 1 (IL-1) and tumour necrosis factor (TNF-) signal transduction
    • Saklatvala J, Davis W, Guesdon F. Interleukin 1 (IL-1) and tumour necrosis factor (TNF-) signal transduction. Philos Trans R Soc Lond B Biol Sci. 1996;351:151-157.
    • (1996) Philos Trans R Soc Lond B Biol Sci. , vol.351 , pp. 151-157
    • Saklatvala, J.1    Davis, W.2    Guesdon, F.3
  • 39
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
    • Han J, Lee JD, Bibbs L, Ulevitch RJ. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science. 1994; 265:808-811.
    • (1994) Science. , vol.265 , pp. 808-811
    • Han, J.1    Lee, J.D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 40
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud J, Gupta S, Rogers JS, et al. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem. 1995;270:7420-7426.
    • (1995) J Biol Chem. , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3
  • 41
    • 0141557549 scopus 로고    scopus 로고
    • A regulatory role for p38 delta MAPK in keratinocyte differentiation: Evidence for p38 delta-ERK1/2 complex formation
    • Efimova T, Broome AM, Eckert RL. A regulatory role for p38 delta MAPK in keratinocyte differentiation: evidence for p38 delta-ERK1/2 complex formation. J Biol Chem. 2003;278:34277-34285.
    • (2003) J Biol Chem. , vol.278 , pp. 34277-34285
    • Efimova, T.1    Broome, A.M.2    Eckert, R.L.3
  • 42
    • 0032544551 scopus 로고    scopus 로고
    • Regulation of human involucrin promoter activity by a protein kinase C, Ras, MEKK1, MEK3, p38/RK, AP1 signal transduction pathway
    • Efimova T, LaCelle P, Welter JF, Eckert RL. Regulation of human involucrin promoter activity by a protein kinase C, Ras, MEKK1, MEK3, p38/RK, AP1 signal transduction pathway. J Biol Chem. 1998;273:24387-24395.
    • (1998) J Biol Chem. , vol.273 , pp. 24387-24395
    • Efimova, T.1    LaCelle, P.2    Welter, J.F.3    Eckert, R.L.4
  • 43
    • 0030475369 scopus 로고    scopus 로고
    • Transcription factor regulation of epidermal keratinocyte gene expression
    • Eckert RL, Welter JF. Transcription factor regulation of epidermal keratinocyte gene expression. Mol Biol Rep. 1996;23:59-70.
    • (1996) Mol Biol Rep. , vol.23 , pp. 59-70
    • Eckert, R.L.1    Welter, J.F.2
  • 44
    • 9444263191 scopus 로고    scopus 로고
    • Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface
    • Luo L, Li DQ, Doshi A, et al. Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface. Invest Ophthalmol Vis Sci. 2004;45:4293-4301.
    • (2004) Invest Ophthalmol Vis Sci. , vol.45 , pp. 4293-4301
    • Luo, L.1    Li, D.Q.2    Doshi, A.3
  • 45
    • 31044453568 scopus 로고    scopus 로고
    • Hyperosmolar saline is a proinflammatory stress on the mouse ocular surface
    • Luo L, Li DQ, Corrales RM, Pflugfelder SC. Hyperosmolar saline is a proinflammatory stress on the mouse ocular surface. Eye Contact Lens. 2005;31:186-193.
    • (2005) Eye Contact Lens. , vol.31 , pp. 186-193
    • Luo, L.1    Li, D.Q.2    Corrales, R.M.3    Pflugfelder, S.C.4
  • 46
    • 44649189409 scopus 로고    scopus 로고
    • NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells
    • Lee JH, Kim M, Im YS, et al. NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. Invest Ophthalmol Vis Sci. 2008;49:1827-1835.
    • (2008) Invest Ophthalmol Vis Sci. , vol.49 , pp. 1827-1835
    • Lee, J.H.1    Kim, M.2    Im, Y.S.3
  • 47
    • 31044455375 scopus 로고    scopus 로고
    • JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells
    • Li DQ, Luo L, Chen Z, et al. JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. Exp Eye Res. 2006;82:588-596.
    • (2006) Exp Eye Res. , vol.82 , pp. 588-596
    • Li, D.Q.1    Luo, L.2    Chen, Z.3
  • 48
    • 40649100353 scopus 로고    scopus 로고
    • Hyperosmolarity-induced cornification of human corneal epithelial cells is regulated by JNK MAPK
    • Chen Z, Tong L, Li Z, et al. Hyperosmolarity-induced cornification of human corneal epithelial cells is regulated by JNK MAPK. Invest Ophthalmol Vis Sci. 2008;49:539-549.
    • (2008) Invest Ophthalmol Vis Sci. , vol.49 , pp. 539-549
    • Chen, Z.1    Tong, L.2    Li, Z.3
  • 49
    • 0035889959 scopus 로고    scopus 로고
    • Selective activation of p38 mitogen-activated protein kinase cascade in human neutrophils stimulated by IL-1beta
    • Suzuki K, Hino M, Kutsuna H, et al. Selective activation of p38 mitogen-activated protein kinase cascade in human neutrophils stimulated by IL-1beta. J Immunol. 2001;167:5940-5947.
    • (2001) J Immunol. , vol.167 , pp. 5940-5947
    • Suzuki, K.1    Hino, M.2    Kutsuna, H.3
  • 50
    • 0033620472 scopus 로고    scopus 로고
    • Bricks and mortar of the epidermal barrier
    • Nemes Z, Steinert PM. Bricks and mortar of the epidermal barrier. Exp Mol Med. 1999;31:5-19.
    • (1999) Exp Mol Med. , vol.31 , pp. 5-19
    • Nemes, Z.1    Steinert, P.M.2
  • 51
    • 0030935565 scopus 로고    scopus 로고
    • The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation
    • Eckert RL, Crish JF, Robinson NA. The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation. Physiol Rev. 1997;77:397-424.
    • (1997) Physiol Rev. , vol.77 , pp. 397-424
    • Eckert, R.L.1    Crish, J.F.2    Robinson, N.A.3
  • 52
  • 53
    • 0034702882 scopus 로고    scopus 로고
    • Functional AP1 and CRE response elements in the human keratinocyte transglutaminase promoter mediating Whn suppression
    • Jessen BA, Qin Q, Rice RH. Functional AP1 and CRE response elements in the human keratinocyte transglutaminase promoter mediating Whn suppression. Gene. 2000;254:77-85.
    • (2000) Gene. , vol.254 , pp. 77-85
    • Jessen, B.A.1    Qin, Q.2    Rice, R.H.3
  • 54
    • 0027761949 scopus 로고
    • Transcription factors positively and negatively regulating the Na, K-ATPase alpha 1 subunit gene
    • Watanabe Y, Kawakami K, Hirayama Y, Nagano K. Transcription factors positively and negatively regulating the Na, K-ATPase alpha 1 subunit gene. J Biochem. 1993;114:849-855.
    • (1993) J Biochem. , vol.114 , pp. 849-855
    • Watanabe, Y.1    Kawakami, K.2    Hirayama, Y.3    Nagano, K.4
  • 55
    • 0026320871 scopus 로고
    • Identification of a zinc finger protein that inhibits IL-2 gene expression
    • Williams TM, Moolten D, Burlein J, et al. Identification of a zinc finger protein that inhibits IL-2 gene expression. Science. 1991; 254:1791-1794.
    • (1991) Science. , vol.254 , pp. 1791-1794
    • Williams, T.M.1    Moolten, D.2    Burlein, J.3
  • 56
    • 0026452863 scopus 로고
    • Basonuclin: A keratinocyte protein with multiple paired zinc fingers
    • Tseng H, Green H. Basonuclin: a keratinocyte protein with multiple paired zinc fingers. Proc Natl Acad Sci U S A. 1992;89:10311-10315.
    • (1992) Proc Natl Acad Sci U S A. , vol.89 , pp. 10311-10315
    • Tseng, H.1    Green, H.2
  • 57
    • 27244444742 scopus 로고    scopus 로고
    • Mutations in TCF8 cause posterior polymorphous corneal dystrophy and ectopic expression of COL4A3 by corneal endothelial cells
    • Krafchak CM, Pawar H, Moroi SE, et al. Mutations in TCF8 cause posterior polymorphous corneal dystrophy and ectopic expression of COL4A3 by corneal endothelial cells. Am J Hum Genet. 2005;77:694-708.
    • (2005) Am J Hum Genet. , vol.77 , pp. 694-708
    • Krafchak, C.M.1    Pawar, H.2    Moroi, S.E.3
  • 58
    • 34249748851 scopus 로고    scopus 로고
    • Novel mutations in the ZEB1 gene identified in Czech and British patients with posterior polymorphous corneal dystrophy
    • Liskova P, Tuft SJ, Gwilliam R, et al. Novel mutations in the ZEB1 gene identified in Czech and British patients with posterior polymorphous corneal dystrophy. Hum Mutat. 2007;28:638.
    • (2007) Hum Mutat. , vol.28 , pp. 638
    • Liskova, P.1    Tuft, S.J.2    Gwilliam, R.3
  • 59
    • 33744769678 scopus 로고    scopus 로고
    • Expression and regulation of cornified envelope proteins in human corneal epithelium
    • Tong L, Corrales RM, Chen Z, et al. Expression and regulation of cornified envelope proteins in human corneal epithelium. Invest Ophthalmol Vis Sci. 2006;47:1938-1946.
    • (2006) Invest Ophthalmol Vis Sci. , vol.47 , pp. 1938-1946
    • Tong, L.1    Corrales, R.M.2    Chen, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.