-
1
-
-
84867338003
-
Discovery and preclinical validation of drug indications using compendia of public gene expression data
-
96ra77
-
Sirota M, Dudley JT, Kim J, Chiang AP, Morgan AA, Sweet-Cordero A et al. Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci Transl Med 2011; 3: 96ra77.
-
(2011)
Sci Transl Med
, vol.3
-
-
Sirota, M.1
Dudley, J.T.2
Kim, J.3
Chiang, A.P.4
Morgan, A.A.5
Sweet-Cordero, A.6
-
2
-
-
84855381399
-
A novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy
-
Jin G, Fu C, Zhao H, Cui K, Chang J, Wong ST. A novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy. Cancer Res 2012; 72: 33-44.
-
(2012)
Cancer Res
, vol.72
, pp. 33-44
-
-
Jin, G.1
Fu, C.2
Zhao, H.3
Cui, K.4
Chang, J.5
Wong, S.T.6
-
3
-
-
84858978535
-
Drug repositioning for personalized medicine
-
Li YY, Jones SJ. Drug repositioning for personalized medicine. Genome Med 2012; 4: 27.
-
(2012)
Genome Med
, vol.4
, pp. 27
-
-
Li, Y.Y.1
Jones, S.J.2
-
4
-
-
77957044703
-
Discovery of drug mode of action and drug repositioning from transcriptional responses
-
Iorio F, Bosotti R, Scacheri E, Belcastro V, Mithbaokar P, Ferriero R et al. Discovery of drug mode of action and drug repositioning from transcriptional responses. Proc Natl Acad Sci USA 2010; 107: 14621-14626.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14621-14626
-
-
Iorio, F.1
Bosotti, R.2
Scacheri, E.3
Belcastro, V.4
Mithbaokar, P.5
Ferriero, R.6
-
5
-
-
84873076688
-
In silico drug repositioning: What we need to know
-
Liu Z, Fang H, Reagan K, Xu X, Mendrick DL, Slikker W Jr. et al. In silico drug repositioning: What we need to know. Drug Discov Today 2013; 18: 110-115.
-
(2013)
Drug Discov Today
, vol.18
, pp. 110-115
-
-
Liu, Z.1
Fang, H.2
Reagan, K.3
Xu, X.4
Mendrick, D.L.5
Slikker Jr., W.6
-
6
-
-
54249155522
-
Network pharmacology: The next paradigm in drug discovery
-
Hopkins AL. Network pharmacology: The next paradigm in drug discovery. Nat Chem Biol 2008; 4: 682-690.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 682-690
-
-
Hopkins, A.L.1
-
7
-
-
78651287426
-
DrugBank 3.0: A Comprehensive Resource For 'omics' research on drugs
-
Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A et al. DrugBank 3.0: A comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 2011; 39: D1035-D1041.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Knox, C.1
Law, V.2
Jewison, T.3
Liu, P.4
Ly, S.5
Frolkis, A.6
-
8
-
-
75549087817
-
An overview of the PubChem BioAssay resource
-
Wang Y, Bolton E, Dracheva S, Karapetyan K, Shoemaker BA, Suzek TO et al. An overview of the PubChem BioAssay resource. Nucleic Acids Res 2010; 38: D255-D266.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Wang, Y.1
Bolton, E.2
Dracheva, S.3
Karapetyan, K.4
Shoemaker, B.A.5
Suzek, T.O.6
-
9
-
-
84859204939
-
The IntAct molecular interaction database in 2012
-
Kerrien S, Aranda B, Breuza L, Bridge A, Broackes-Carter F, Chen C et al. The IntAct molecular interaction database in 2012. Nucleic Acids Res 2012; 40: D841-D846.
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Kerrien, S.1
Aranda, B.2
Breuza, L.3
Bridge, A.4
Broackes-Carter, F.5
Chen, C.6
-
10
-
-
79959925808
-
BioProfiling.de: Analytical web portal for high-Throughput cell biology
-
Antonov AV. BioProfiling.de: Analytical web portal for high-Throughput cell biology. Nucleic Acids Res 2011; 39: W323-W327.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Antonov, A.V.1
-
11
-
-
84861995326
-
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells
-
Sachlos E, Risueño RM, Laronde S, Shapovalova Z, Lee JH, Russell J et al. Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Cell 2012; 149: 1284-1297.
-
(2012)
Cell
, vol.149
, pp. 1284-1297
-
-
Sachlos, E.1
Risueño, R.M.2
Laronde, S.3
Shapovalova, Z.4
Lee, J.H.5
Russell, J.6
-
12
-
-
84862732904
-
Stem cells Antipsychotic to anticancer agent?
-
Burgess DJ. Stem cells. Antipsychotic to anticancer agent? Nat Rev Cancer 2012; 12: 452-453.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 452-453
-
-
Burgess, D.J.1
-
13
-
-
0026775668
-
Tamoxifen-resistant human breast cancer cell growth: Inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13
-
Strobl JS, Peterson VA. Tamoxifen-resistant human breast cancer cell growth: Inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13. J Pharmacol Exp Ther 1992; 263: 186-193.
-
(1992)
J Pharmacol Exp Ther
, vol.263
, pp. 186-193
-
-
Strobl, J.S.1
Peterson, V.A.2
-
14
-
-
22344434177
-
Benign breast disease and the risk of breast cancer
-
Hartmann LC, Sellers TA, Frost MH, Lingle WL, Degnim AC, Ghosh K et al. Benign breast disease and the risk of breast cancer. N Engl J Med 2005; 353: 229-237.
-
(2005)
N Engl J Med
, vol.353
, pp. 229-237
-
-
Hartmann, L.C.1
Sellers, T.A.2
Frost, M.H.3
Lingle, W.L.4
Degnim, A.C.5
Ghosh, K.6
-
15
-
-
0020518140
-
Danazol treatment for advanced breast cancer
-
Coombes RC, Perez D, Gazet JC, Ford HT, Powles TJ. Danazol treatment for advanced breast cancer. Cancer Chemother Pharmacol 1983; 10: 194-195.
-
(1983)
Cancer Chemother Pharmacol
, vol.10
, pp. 194-195
-
-
Coombes, R.C.1
Perez, D.2
Gazet, J.C.3
Ford, H.T.4
Powles, T.J.5
-
16
-
-
33750986839
-
Erlotinib-induced breast cancer regression
-
Catania C, De Pas TM, Pelosi G, Manzotti M, Adamoli L, Nolè F et al. Erlotinib-induced breast cancer regression. Ann Pharmacother 2006; 40: 2043-2047.
-
(2006)
Ann Pharmacother
, vol.40
, pp. 2043-2047
-
-
Catania, C.1
De Pas, T.M.2
Pelosi, G.3
Manzotti, M.4
Adamoli, L.5
Nolè, F.6
-
17
-
-
39749085432
-
Short preoperative treatment with erlotinib inhibits tumor cell proliferation in hormone receptor-positive breast cancers
-
Guix M, Granja Nde M, Meszoely I, Adkins TB, Wieman BM, Frierson KE et al. Short preoperative treatment with erlotinib inhibits tumor cell proliferation in hormone receptor-positive breast cancers. J Clin Oncol 2008; 26: 897-906.
-
(2008)
J Clin Oncol
, vol.26
, pp. 897-906
-
-
Guix, M.1
Granja Nde, M.2
Meszoely, I.3
Adkins, T.B.4
Wieman, B.M.5
Frierson, K.E.6
-
18
-
-
84862988257
-
Sorafenib in combination with capecitabine: An oral regimen for patients with HER2-negative locally advanced or metastatic breast cancer
-
Baselga J, Segalla JG, Roché H, Del Giglio A, Pinczowski H, Ciruelos EM et al. Sorafenib in combination with capecitabine: An oral regimen for patients with HER2-negative locally advanced or metastatic breast cancer. J Clin Oncol 2012; 30: 1484-1491.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1484-1491
-
-
Baselga, J.1
Segalla, J.G.2
Roché, H.3
Del Giglio, A.4
Pinczowski, H.5
Ciruelos, E.M.6
-
19
-
-
2442669093
-
Preclinical evaluation of the tyrosine kinase inhibitor su11248 as a single agent and in combination with "standard of care" therapeutic agents for the treatment of breast cancer
-
Abrams TJ, Murray LJ, Pesenti E, Holway VW, Colombo T, Lee LB et al. Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with "standard of care" therapeutic agents for the treatment of breast cancer. Mol Cancer Ther 2003; 2: 1011-1021.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1011-1021
-
-
Abrams, T.J.1
Murray, L.J.2
Pesenti, E.3
Holway, V.W.4
Colombo, T.5
Lee, L.B.6
-
20
-
-
9144274970
-
SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model
-
Murray LJ, Abrams TJ, Long KR, Ngai TJ, Olson LM, Hong W et al. SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model. Clin Exp Metastasis 2003; 20: 757-766.
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 757-766
-
-
Murray, L.J.1
Abrams, T.J.2
Long, K.R.3
Ngai, T.J.4
Olson, L.M.5
Hong, W.6
-
21
-
-
84860625265
-
First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: Results of a prospective, randomized phase III study
-
Bergh J, Bondarenko IM, Lichinitser MR, Liljegren A, Greil R, Voytko NL et al. First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: Results of a prospective, randomized phase III study. J Clin Oncol 2012; 30: 921-929.
-
(2012)
J Clin Oncol
, vol.30
, pp. 921-929
-
-
Bergh, J.1
Bondarenko, I.M.2
Lichinitser, M.R.3
Liljegren, A.4
Greil, R.5
Voytko, N.L.6
-
22
-
-
84969947743
-
Abstract 3727: Targeting autotaxin to reduce chemotherapy resistance in ovarian cancer
-
Supplement 1
-
Zhai L, Zamani A, Liu X, Wang Y, Maxuitenko Y, Alvarez R et al. Abstract 3727: Targeting autotaxin to reduce chemotherapy resistance in ovarian cancer. Cancer Res 2012; 72, Supplement 1.
-
(2012)
Cancer Res
, vol.72
-
-
Zhai, L.1
Zamani, A.2
Liu, X.3
Wang, Y.4
Maxuitenko, Y.5
Alvarez, R.6
-
23
-
-
33747597785
-
Hexachlorophene inhibits Wnt/betacatenin pathway by promoting Siah-mediated beta-catenin degradation
-
Park S, Gwak J, Cho M, Song T, Won J, Kim DE et al. Hexachlorophene inhibits Wnt/betacatenin pathway by promoting Siah-mediated beta-catenin degradation. Mol Pharmacol 2006; 70: 960-966.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 960-966
-
-
Park, S.1
Gwak, J.2
Cho, M.3
Song, T.4
Won, J.5
Kim, D.E.6
-
24
-
-
33749335282
-
The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
-
Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ et al. The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease. Science 2006; 313: 1929-1935.
-
(2006)
Science
, vol.313
, pp. 1929-1935
-
-
Lamb, J.1
Crawford, E.D.2
Peck, D.3
Modell, J.W.4
Blat, I.C.5
Wrobel, M.J.6
-
25
-
-
33845876254
-
The Connectivity Map: A new tool for biomedical research
-
Lamb J. The Connectivity Map: A new tool for biomedical research. Nature reviews. Cancer 2007; 7: 54-60.
-
(2007)
Nature reviews. Cancer
, vol.7
, pp. 54-60
-
-
Lamb, J.1
-
26
-
-
78651339534
-
NCBI GEO: Archive for functional genomics data sets-10 years on
-
Barrett T, Troup DB, Wilhite SE, Ledoux P, Evangelista C, Kim IF et al. NCBI GEO: Archive for functional genomics data sets-10 years on. Nucleic Acids Res 2011; 39: D1005-D1010.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Barrett, T.1
Troup, D.B.2
Wilhite, S.E.3
Ledoux, P.4
Evangelista, C.5
Kim, I.F.6
-
27
-
-
84872360829
-
MIRUMIR: An online tool to test microRNAs as biomarkers to predict survival in cancer using multiple clinical data sets
-
Antonov AV, Knight RA, Melino G, Barlev NA, Tsvetkov PO. MIRUMIR: An online tool to test microRNAs as biomarkers to predict survival in cancer using multiple clinical data sets. Cell Death Differ 2013; 20: 367.
-
(2013)
Cell Death Differ
, vol.20
, pp. 367
-
-
Antonov, A.V.1
Knight, R.A.2
Melino, G.3
Barlev, N.A.4
Tsvetkov, P.O.5
-
28
-
-
84898015237
-
PPISURV: A novel bioinformatics tool for uncovering the hidden role of specific genes in cancer survival outcome
-
e-pub ahead of print 30 May 2013 doi:10.1038/onc.2013.119
-
Antonov AV, Krestyaninova M, Knight RA, Rodchenkov I, Melino G, Barlev NA. PPISURV: A novel bioinformatics tool for uncovering the hidden role of specific genes in cancer survival outcome. Oncogene; e-pub ahead of print 30 May 2013; doi:10.1038/ onc.2013.119.
-
Oncogene
-
-
Antonov, A.V.1
Krestyaninova, M.2
Knight, R.A.3
Rodchenkov, I.4
Melino, G.5
Barlev, N.A.6
-
29
-
-
33748208652
-
A class of rank test procedures for censored survival data
-
D H T F.
-
D H, T F. A class of rank test procedures for censored survival data. Biometrika 1982; 69: 553-566.
-
(1982)
Biometrika
, vol.69
, pp. 553-566
-
-
-
30
-
-
62149124281
-
TICL-A web tool for network-based interpretation of compound lists inferred by high-Throughput metabolomics
-
Antonov AV, Dietmann S, Wong P, Mewes HW. TICL-A web tool for network-based interpretation of compound lists inferred by high-Throughput metabolomics. FEBS J 2009; 276: 2084-2094.
-
(2009)
FEBS J
, vol.276
, pp. 2084-2094
-
-
Antonov, A.V.1
Dietmann, S.2
Wong, P.3
Mewes, H.W.4
-
31
-
-
0025066941
-
More powerful procedures for multiple significance testing
-
Hochberg Y, Benjamini Y. More powerful procedures for multiple significance testing. Statistics in medicine 1990; 9: 811-818.
-
(1990)
Statistics in medicine
, vol.9
, pp. 811-818
-
-
Hochberg, Y.1
Benjamini, Y.2
|