Organocatalytic asymmetric michael/friedel-crafts cascade reaction of 3-pyrrolyl-oxindoles and α, β-unsaturated aldehydes for the construction of chiral spiro[5,6-dihydropyrido[1,2- a ]pyrrole-3,3′-oxindoles]

Journal of Organic Chemistry

Volumn 80, Issue 11, 2015, Pages 5951-5957

  You, Yong ^a,c   Cui, Bao Dong ^b   Zhou, Ming Qiang ^a,c   Zuo, Jian ^a,c   Zhao, Jian Qiang ^a,c   Xu, Xiao Ying ^a   Zhang, Xiao Mei ^a   Yuan, Wei Cheng ^a  

^a CHENGDU INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b ZUNYI MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; AROMATIC COMPOUNDS;

ASYMMETRIC REACTION; CASCADE PROCESS; CASCADE REACTIONS; DIASTEREO- AND ENANTIOSELECTIVITY; ORGANOCATALYTIC; PTOLUENESULFONIC ACID; SILYL ETHERS; UNSATURATED ALDEHYDES;

UNSATURATED COMPOUNDS;

3 PYRROLYL OXINDOLE; ALDEHYDE DERIVATIVE; ALPHA BETA UNSATURATED ALDEHYDE; BENZOIC ACID; CHIRAL SPIRO[5,6 DIHYDROPYRIDO[1,2 A]PYRROLE 3,3' OXINDOLE]; OXINDOLE; PARA TOLUENESULFONIC ACIC; PYRROLE DERIVATIVE; TOLUENESULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ALDEHYDE; INDOLE DERIVATIVE; SPIRO COMPOUND;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYST; CHEMICAL STRUCTURE; ELECTRON TRANSPORT; FRIEDEL CRAFTS REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGENATION; MELTING POINT; MICHAEL ADDITION; PROTON NUCLEAR MAGNETIC RESONANCE; ROOM TEMPERATURE; STEREOCHEMISTRY; X RAY ANALYSIS; CATALYSIS; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

ALDEHYDES; CATALYSIS; INDOLES; MOLECULAR STRUCTURE; PYRROLES; SPIRO COMPOUNDS; STEREOISOMERISM;

EID: 84930966102     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/acs.joc.5b00597     Document Type: Article

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