Uncoupling protein 1 binds one nucleotide per monomer and is stabilized by tightly bound cardiolipin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 22, 2015, Pages 6973-6978

  Lee, Yang ^a,c   Willers, Chrissie ^b   Kunji, Edmund R S ^a   Crichton, Paul G ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Brown fat; Cardiolipin binding; Membrane protein; Nucleotide binding; Oligomeric state

Indexed keywords

CARDIOLIPIN; MONOMER; NUCLEOTIDE; NUCLEOTIDE BINDING PROTEIN; UNCOUPLING PROTEIN 1; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN;

ANIMAL CELL; ARTICLE; CALORIMETRY; CHROMATOGRAPHY; LAMB; LIPID ANALYSIS; MITOCHONDRION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STABILITY; STOICHIOMETRY; ANIMAL; BROWN ADIPOSE TISSUE; CIRCULAR DICHROISM; GENETICS; HUMAN; IMMUNOBLOTTING; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; SHEEP; SIZE EXCLUSION CHROMATOGRAPHY; THERMOGENESIS;

ADIPOSE TISSUE, BROWN; ANIMALS; CALORIMETRY; CARDIOLIPINS; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; HUMANS; IMMUNOBLOTTING; ION CHANNELS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NUCLEOTIDES; SHEEP; THERMOGENESIS;

EID: 84930959315     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1503833112     Document Type: Article

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