Trends in thermostability provide information on the nature of substrate, inhibitor, and lipid interactions with mitochondrial carriers

Journal of Biological Chemistry

Volumn 290, Issue 13, 2015, Pages 8206-8217

  Crichton, Paul G ^a   Lee, Yang ^a   Ruprecht, Jonathan J ^a   Cerson, Elizabeth ^a   Thangaratnarajah, Chancievan ^a   King, Martin S ^a   Kunji, Edmund R S ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; STABILITY;

, INHIBITOR; MEASUREMENTS OF; MEMBRANE PROTEINS; MITOCHONDRIAL CARRIER; RAPID ASSESSMENT; SMALL MOLECULES;

PROTEINS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BONGKREKIC ACID; CARBOXYATRACTYLOSIDE; CARDIOLIPIN; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; PROTEOLIPOSOME; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 1; ADENINE NUCLEOTIDE TRANSLOCASE; DETERGENT; ENZYME INHIBITOR; ION CHANNEL; LIPID; MICELLE; MITOCHONDRIAL UNCOUPLING PROTEIN; PET9 PROTEIN, S CEREVISIAE; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE PROTEIN;

AFFINITY CHROMATOGRAPHY; ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CYANIDIOSCHYZON MEROLAE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GALDIERIA SULFURARIA; GENE SEQUENCE; LIGAND BINDING; MESOPHILE; MICELLE; MITOCHONDRION; MYCELIOPHTHORA THERMOPHILA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; THERMOMYCES LANUGINOSUS; THERMOSTABILITY; YEAST; ANTAGONISTS AND INHIBITORS; CHEMISTRY; HUMAN; PROTEIN DENATURATION; SOLUBILITY; TRANSITION TEMPERATURE;

CARDIOLIPINS; DETERGENTS; ENZYME INHIBITORS; HUMANS; ION CHANNELS; LIPIDS; MICELLES; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL PROTEINS; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN STABILITY; SACCHAROMYCES CEREVISIAE PROTEINS; SOLUBILITY; TRANSITION TEMPERATURE;

EID: 84925798847     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.616607     Document Type: Article

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