Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat

Neuropsychopharmacology

Volumn 39, Issue 11, 2014, Pages 2601-2610

  Ciccocioppo, Roberto ^a   Stopponi, Serena ^a   Economidou, Daina ^a   Kuriyama, Makoto ^b   Kinoshita, Hiroshi ^b   Heilig, Markus ^c   Roberto, Marisa ^d   Weiss, Friedbert ^d   Teshima, Koji ^b  

^a UNIVERSITY OF CAMERINO   (Italy)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2-(3-(1-(ACENAPHTHEN-1-YL)PIPERIDIN-4-YL)-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-1-YL)-N-METHYLACETAMIDE; ACENAPHTHENE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; DRUGS USED IN THE TREATMENT OF ADDICTION; NALTREXONE; NARCOTIC ANTAGONIST; NOCICEPTIN; NOCICEPTIN RECEPTOR; OPIATE PEPTIDE; OPIATE RECEPTOR;

AGONISTS; ANIMAL; COMPLICATION; DECISION MAKING; DOSE RESPONSE; DRINKING BEHAVIOR; DRUG EFFECTS; DRUG SEEKING BEHAVIOR; HEK293 CELL LINE; HUMAN; MALE; MENTAL STRESS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SUBSTANCE WITHDRAWAL SYNDROME; WISTAR RAT;

ACENAPHTHENES; ALCOHOL DETERRENTS; ALCOHOL DRINKING; ANIMALS; BENZIMIDAZOLES; CHOICE BEHAVIOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-SEEKING BEHAVIOR; HEK293 CELLS; HUMANS; MALE; NALTREXONE; NARCOTIC ANTAGONISTS; OPIOID PEPTIDES; RATS; RATS, WISTAR; RECEPTORS, OPIOID; STRESS, PSYCHOLOGICAL; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84930906133     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.113     Document Type: Article

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