Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 18, 1999, Pages 10444-10449

  Köster, Anja ^a,e   Montkowski, Alexandra ^b   Schulz, Stefan ^c   Stübe, Eva Maria ^b   Knaudt, Kristina ^b   Jenck, Francois ^a   Moreau, Jean Luc ^a   Nothacker, Hans Peter ^d   Civelli, Olivier ^d   Reinscheid, Rainer K ^b,d  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b UNIVERSITY OF HAMBURG   (Germany)

^c OTTO VON GUERICKE UNIVERSITY   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; NOCICEPTIN;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; COPING BEHAVIOR; GENE; GENE DISRUPTION; IMMUNOHISTOCHEMISTRY; MOUSE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; STRESS;

ANALGESIA; ANIMALS; ANXIETY; CORTICOSTERONE; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HOMOZYGOTE; MAZE LEARNING; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; OPIOID PEPTIDES; PAIN; PERCEPTION; RECEPTORS, OPIOID; SPACE PERCEPTION; STRESS, PSYCHOLOGICAL;

ANIMALIA; RODENTIA;

EID: 0037802203     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.18.10444     Document Type: Article

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