Orphanin FQ is a functional anti-opioid peptide

Neuroscience

Volumn 75, Issue 2, 1996, Pages 333-337

  Mogil, J S ^a   Grisel, J E ^a   Reinscheid, R K ^b,c   Civelli, O ^b,c   Belknap, J K ^a   Grandy, D K ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHINE; NALOXONE; OPIATE AGONIST; OPIATE ANTAGONIST; OPIATE PEPTIDE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BEHAVIOR; CONTROLLED STUDY; FEMALE; HYPERALGESIA; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030601730     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(96)00338-7     Document Type: Article

References (20)

1. Ankier S. I. New hot plate tests to quantify antinociceptive and narcotic antagonist actions. Eur. J. Pharmac. 27:1974;1-4.
2. Basbaum A. I., Fields H. L. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. A. Rev. Neurosci. 7:1984;309-338.
3. Ben-Bassat J., Peretz E., Sulman F. G. Analgesimetry and ranking of analgesic drugs by the receptacle method. Archs int. Pharmacodyn. Thér. 122:1959;434-447.
4. Bunzow J. R., Saez C., Mortrud M., Bouvier C., Williams J. T., Low M., Grandy D. K. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or κ opioid receptor type. Fedn Eur. biochem. Socs Lett. 347:1994;284-288.
5. d'Amore A., Chiarotti F., Renzi P. High-intensity nociceptive stimuli minimize behavioral effects induced by restraining stress during the tail-flick test. J. pharmac. toxic. Meth. 27:1992;197-201.
6. Evans C. J., Keith D. E. Jr., Morrison H., Magendzo K., Edwards R. H. Cloning of a delta opioid receptor by functional expression. Science. 258:1992;1952-1955.
7. Hammond D. L. (1989) Inference of pain and its modulation from simple behaviors. In Advances in Pain Research and Therapy: Issues in Pain Management (eds Chapman C. R. and Loeser J. D.), pp. 69-91. Raven Press, New York.
8. Kelly D. D. (ed.) (1986) Stress-induced analgesia. Ann. N. Y. Acad. Sci. 467.
9. Kieffer B. L., Befort K., Gaveriaux-Ruff C., Hirth C. G. The δ-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc. natn. Acad. Sci. U.S.A. 89:1992;12048-12052.
10. Koster R., Anderson M., de Beer E. J. Acetic acid for analgesic screening. Fedn Proc. 18:1959;412.
11. Laursen S. E., Belknap J. K. Intracerebroventricular injections in mice: some methodological refinements. J. pharmac. Meth. 16:1986;355-357.
12. Lewis J. W., Cannon J. T., Liebeskind J. C. Opioid and non-opioid mechanisms of stress analgesia. Science. 208:1980;623-625.
13. 1 receptor. Nature. 377:1995;532-535.
14. Pasternak G. W. Pharmacological mechanisms of opioid analgesics. Clin. Neuropharmac. 16:1993;1-18.
15. Porro C. A., Carli G. Immobilization and restraint effects on pain reactions in animals. Pain. 32:1988;289-307.
16. Reinscheid R. K., Nothacker H.-P., Bourson A., Ardati A., Henningsen R. A., Bunzow J. R., Grandy D. K., Langen H., Monsma F. J., Civelli O. Orphanin FQ: a novel neuropeptide which is a natural ligand of an opioid-like G protein-coupled receptor. Science. 270:1995;792-794.
17. Rothman R. B. A review of the role of anti-opioid peptides in morphine tolerance and dependence. Synapse. 12:1992;129-138.
18. Watkins L. R., Mayer D. J. The organization of endogenous opiate and nonopiate pain control system. Science. 216:1982;1185-1192.
19. Yaksh T. L., Rudy T. A. Narcotic analgesics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques. Pain. 4:1978;299-359.
20. Zhang S., Yu L. Identification of dynorphins as endogenous ligands for an opioid receptor-like orphan receptor. J. biol. Chem. 270:1995;22772-22776.