MicroPET imaging of CD13 expression using a 64Cu-labeled dimeric NGR peptide based on sarcophagine cage

Molecular Pharmaceutics

Volumn 11, Issue 11, 2014, Pages 3938-3946

  Li, Guoquan ^a,b   Wang, Xinlu ^a,c   Zong, Shu ^b   Wang, Jing ^b   Conti, Peter S ^a   Chen, Kai ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

Author keywords

64Cu labeling; Bivalency effect; Catalyst free click chemistry; CD13; NGR peptide; PET imaging; Tumor angiogenesis

Indexed keywords

ARGININE DERIVATIVE; ASPARAGINYLGLYCYLARGININE; ASPARAGINYLGLYCYLARGININE SARCOPHAGINE CU 64; AZIDE; CHELATING AGENT; COPPER CHLORIDE CU 64; MICROSOMAL AMINOPEPTIDASE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; COPPER; GAMMA BUTYROLACTONE; NGR PEPTIDE; OLIGOPEPTIDE; PEPTIDE; SARCOPHINE;

ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; BREAST ADENOCARCINOMA; CELL LINE; CELL TRANSPORT; CLICK CHEMISTRY; CONTROLLED STUDY; DIMERIZATION; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG PROTEIN BINDING; DRUG STABILITY; DRUG SYNTHESIS; FEMALE; FIBROSARCOMA; FIBROSARCOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LIPOPHILICITY; MCF 7 CELL LINE; MICRO POSITRON EMISSION TOMOGRAPHY; MOLECULAR IMAGING; MOUSE; NONHUMAN; PET SCANNER; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIOCHEMISTRY; TUMOR CELL; TUMOR XENOGRAFT; ANALOGS AND DERIVATIVES; ANIMAL; CANCER TRANSPLANTATION; CATALYSIS; CHEMISTRY; GENE EXPRESSION REGULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER; NEOVASCULARIZATION (PATHOLOGY); NUDE MOUSE; SCINTISCANNING; TISSUE DISTRIBUTION; TUMOR CELL LINE;

4-BUTYROLACTONE; ANIMALS; ANTIGENS, CD13; CATALYSIS; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLICK CHEMISTRY; COPPER RADIOISOTOPES; DIMERIZATION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LIVER; MCF-7 CELLS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; OLIGOPEPTIDES; PEPTIDES; POSITRON-EMISSION TOMOGRAPHY; TISSUE DISTRIBUTION;

EID: 84930896294     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500354x     Document Type: Article

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