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Bioorganic and Medicinal Chemistry

Volumn 23, Issue 14, 2015, Pages 4082-4091

Promiscuity and selectivity of bitter molecules and their receptors

(2) Di Pizio, Antonella a Niv, Masha Y a

a HEBREW UNIVERSITY OF JERUSALEM (Israel)

Author keywords

Canonical binding site; Chemical senses; Chemosensory; GPCR; Modeling; Molecular recognition; Orthosteric

Indexed keywords

G PROTEIN COUPLED RECEPTOR; PROTEIN TAS2R; UNCLASSIFIED DRUG; LIGAND; MOLECULAR LIBRARY; TAS2R1 PROTEIN, HUMAN;

ARTICLE; BINDING SITE; BITTER TASTE; CHEMOSENSITIVITY; HUMAN; LIGAND BINDING; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN STRUCTURE; TASTE BUD; ANIMAL; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; PRECLINICAL STUDY; PROCEDURES; TASTE; THEORETICAL MODEL;

ANURA;

ANIMALS; DRUG EVALUATION, PRECLINICAL; HUMANS; LIGANDS; MODELS, THEORETICAL; RECEPTORS, G-PROTEIN-COUPLED; SMALL MOLECULE LIBRARIES; TASTE;

EID: 84930870868 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2015.04.025 Document Type: Article

Times cited : (98)

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