Tuning properties of avian and frog bitter taste receptors dynamically fit gene repertoire sizes

Molecular Biology and Evolution

Volumn 31, Issue 12, 2014, Pages 3216-3227

  Behrens, Maik ^a   Korsching, Sigrun I ^b   Meyerhof, Wolfgang ^a  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Bitter taste receptor; Evolution; G protein coupled receptor; Heterologous expression

Indexed keywords

ANURA; ARTICLE; BIRD; BITTER TASTE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EFFECTIVE CONCENTRATION; GENE; NONHUMAN; PHYLOGENETIC TREE; PHYLOGENY; TAENIOPYGIA GUTTATA; TAS2R GENE; TASTE BUD; AGONISTS; ANIMAL; GENETICS; HEK293 CELL LINE; HUMAN; MOLECULAR EVOLUTION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

AMPHIBIAN PROTEIN; AVIAN PROTEIN; CELL SURFACE RECEPTOR; DENATONIUM BENZOATE; NOSCAPINE; QUATERNARY AMMONIUM DERIVATIVE;

AMPHIBIAN PROTEINS; ANIMALS; ANURA; AVIAN PROTEINS; BIRDS; EVOLUTION, MOLECULAR; HEK293 CELLS; HUMANS; NOSCAPINE; PHYLOGENY; QUATERNARY AMMONIUM COMPOUNDS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TASTE BUDS;

EID: 84920151364     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msu254     Document Type: Article

References (40)

1. Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS. 2000. A novel family of mammalian taste receptors. Cell 100:693-702.
2. Altner H. 1962. Untersuchungen über Leistungen und Bau der Nase des südafrikanischen Krallenfrosches Xenopus laevis (Daudin, 1803). Z Vergl Physiol. 45:272-306.
3. Behrens M, Brockhoff A, Kuhn C, Bufe B, Winnig M, Meyerhof W. 2004. The human taste receptor hTAS2R14 responds to a variety of different bitter compounds. Biochem Biophys Res Commun. 319:479-485.
4. Behrens M, Meyerhof W. 2011. Gustatory and extragustatory functions of mammalian taste receptors. Physiol Behav. 105:4-13.
5. Born S, Levit A, Niv MY, Meyerhof W, Behrens M. 2013. The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands. J Neurosci. 33:201-213.
6. Brockhoff A, Behrens M, Massarotti A, Appendino G, Meyerhof W. 2007. Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium. J Agric Food Chem. 55:6236-6243.
7. Brockhoff A, Behrens M, Niv MY, Meyerhof W. 2010. Structural requirements of bitter taste receptor activation. Proc Natl Acad Sci U S A. 107:11110-11115.
8. Brockhoff A, Behrens M, Roudnitzky N, Appendino G, Avonto C, Meyerhof W. 2011. Receptor agonism and antagonism of dietary bitter compounds. J Neurosci. 31:14775-14782.
9. Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W. 2002. The human TAS2R16 receptor mediates bitter taste in response to betaglucopyranosides. Nat Genet. 32:397-401.
10. Chandrashekar J, Mueller KL, Hoon MA, Adler E, Feng L, Guo W, Zuker CS, Ryba NJ. 2000. T2Rs function as bitter taste receptors. Cell 100:703-711.
11. Chevenet F, Brun C, Banuls AL, Jacq B, Christen R. 2006. TreeDyn: towards dynamic graphics and annotations for analyses of trees. BMC Bioinformatics 7:439.
12. Davis JK, Lowman JJ, Thomas PJ, ten Hallers BF, Koriabine M, Huynh LY, Maney DL, de Jong PJ, Martin CL, Thomas JW. 2010. Evolution of a bitter taste receptor gene cluster in a New World sparrow. Genome Biol Evol. 2:358-370.
13. Dehkordi O, Rose JE, Fatemi M, Allard JS, Balan KV, Young JK, Fatima S, Millis RM, Jayam-Trouth A. 2012. Neuronal expression of bitter taste receptors and downstream signaling molecules in the rat brainstem. Brain Res. 1475:1-10.
14. Dong D, Jones G, Zhang S. 2009. Dynamic evolution of bitter taste receptor genes in vertebrates. BMC Evol Biol. 9:12.
15. Ellegren H. 2007. Molecular evolutionary genomics of birds. Cytogenet Genome Res. 117:120-130.
16. Finger TE, Kinnamon SC. 2011. Taste isn't just for taste buds anymore. F1000 Biol Rep. 3:20.
17. Freitag J, Krieger J, Strotmann J, Breer H. 1995. Two classes of olfactory receptors in Xenopus laevis. Neuron 15:1383-1392.
18. Guindon S, Dufayard JF, Lefort V, Anisimova M, Hordijk W, Gascuel O. 2010. New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst Biol. 59:307-321.
19. Hackett SJ, Kimball RT, Reddy S, Bowie RC, Braun EL, Braun MJ, Chojnowski JL, Cox WA, Han KL, Harshman J, et al. 2008. A phylogenomic study of birds reveals their evolutionary history. Science 320:1763-1768.
20. Imai H, Suzuki N, Ishimaru Y, Sakurai T, Yin L, Pan W, Abe K, Misaka T, Hirai H. 2012. Functional diversity of bitter taste receptor TAS2R16 in primates. Biol Lett. 8:652-656.
21. Katoh K, Misawa K, Kuma K, Miyata T. 2002. MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. Nucleic Acids Res. 30:3059-3066.
22. Kudo K, Shiraishi J, Nishimura S, Bungo T, Tabata S. 2010. The number of taste buds is related to bitter taste sensitivity in layer and broiler chickens. Anim Sci J. 81:240-244.
23. Lagerstrom MC, Hellstrom AR, Gloriam DE, Larsson TP, Schioth HB, Fredriksson R. 2006. The G protein-coupled receptor subset of the chicken genome. PLoS Comput Biol. 2:e54.
24. Li F. 2013. Taste perception: from the tongue to the testis. Mol Hum Reprod. 19:349-360.
25. Matsunami H, Montmayeur JP, Buck LB. 2000. A family of candidate taste receptors in human and mouse. Nature 404:601-604.
26. Mayoral JG, Nouzova M, Brockhoff A, Goodwin M, Hernandez-Martinez S, Richter D, Meyerhof W, Noriega FG. 2010. Allatostatin-C receptors in mosquitoes. Peptides 31:442-450.
27. Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, Bufe B, Appendino G, Behrens M. 2010. The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses. 35:157-170.
28. Mueller KL, Hoon MA, Erlenbach I, Chandrashekar J, Zuker CS, Ryba NJ. 2005. The receptors and coding logic for bitter taste. Nature 434:225-229.
29. Nouzova M, Brockhoff A, Mayoral JG, Goodwin M, Meyerhof W, Noriega FG. 2012. Functional characterization of an allatotropin receptor expressed in the corpora allata of mosquitoes. Peptides 34:201-208.
30. Oike H, Nagai T, Furuyama A, Okada S, Aihara Y, Ishimaru Y, Marui T, Matsumoto I, Misaka T, Abe K. 2007. Characterization of ligands for fish taste receptors. J Neurosci. 27:5584-5592.
31. Richard S, Davies DC. 2000. Comparison of methyl anthranilate and denatonium benzoate as aversants for learning in chicks. Physiol Behav. 70:521-525.
32. Roura E, Baldwin M, Klasing K. 2012. The avian taste system: an update. Proceedings of the 23rd Annual Australian poultry science symposium; 2012. Sydney (Australia): Poultry Research Foundation.
33. Sainz E, Cavenagh MM, Gutierrez J, Battey JF, Northup JK, Sullivan SL. 2007. Functional characterization of human bitter taste receptors. Biochem J. 403:537-543.
34. Shi P, Zhang J. 2006. Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes. Mol Biol Evol. 23:292-300.
35. Singh N, Vrontakis M, Parkinson F, Chelikani P. 2011. Functional bitter taste receptors are expressed in brain cells. Biochem Biophys Res Commun. 406:146-151.
36. Syed AS, Sansone A, Nadler W, Manzini I, Korsching SI. 2013. Ancestral amphibian v2rs are expressed in the main olfactory epithelium. Proc Natl Acad Sci U S A. 110:7714-7719.
37. Thalmann S, Behrens M, Meyerhof W. 2013. Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol. Biochem Biophys Res Commun. 435:267-273.
38. Ueda T, Ugawa S, Yamamura H, Imaizumi Y, Shimada S. 2003. Functional interaction between T2R taste receptors and G-protein alpha subunits expressed in taste receptor cells. J Neurosci. 23:7376-7380.
39. Wooding S, Bufe B, Grassi C, Howard MT, Stone AC, Vazquez M, Dunn DM, Meyerhof W, Weiss RB, Bamshad MJ. 2006. Independent evolution of bitter-taste sensitivity in humans and chimpanzees. Nature 440:930-934.
40. Yoshii K, Yoshii C, Kobatake Y, Kurihara K. 1982. High sensitivity of Xenopus gustatory receptors to amino acids and bitter substances. Am J Physiol. 243:R42-R48.