The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity

Journal of Cell Science

Volumn 128, Issue 11, 2015, Pages 2085-2095

  Furmanski, Anna L ^a,c   Barbarulo, Alessandro ^a   Solanki, Anisha ^a   Lau, Ching In ^a   Sahni, Hemant ^a   Saldana, Jose Ignacio ^a   D'Acquisto, Fulvio ^b   Crompton, Tessa ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY OF BEDFORDSHIRE   (United Kingdom)

Author keywords

AP 1; Gli2; Hedgehog; IL 2; NF B; T cell; TCR

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SONIC HEDGEHOG PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR NFAT2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; KRUPPEL LIKE FACTOR; LYMPHOCYTE ANTIGEN RECEPTOR; NFATC1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CD4+ T LYMPHOCYTE; CELL NUCLEUS; CELL SURVIVAL; COMPLEX FORMATION; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOMODULATION; INFLAMMATION; LYMPHOCYTE PROLIFERATION; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TISSUE INJURY; TISSUE REPAIR; TRANSCRIPTION REGULATION; TUMOR MICROENVIRONMENT; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; LYMPHOCYTE ACTIVATION; METABOLISM; T LYMPHOCYTE; TRANSCRIPTION INITIATION; UPREGULATION;

ERINACEIDAE;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE EXPRESSION REGULATION; HEDGEHOG PROTEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84930804950     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.165803     Document Type: Article

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