Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes

Biochemical Journal

Volumn 467, Issue 2, 2015, Pages 231-245

  Martins Marques, Tania ^a   Catarino, Steve ^a   Zuzarte, Monica ^a   Marques, Carla ^a   Matafome, Paulo ^a,b   Pereira, Paulo ^a   Girão, Henrique ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b POLYTECHNIC INSTITUTE OF COIMBRA   (Portugal)

Author keywords

Autophagy; Cardiomyocyte; Cx43; Gap junction; Ischaemia

Indexed keywords

BECLIN 1; CONNEXIN 43; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE 15; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN P62; UBIQUITIN; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, MOUSE; BECN1 PROTEIN, RAT; CALCIUM BINDING PROTEIN; CONNEXIN 43 PROTEIN, RAT; EPS15 PROTEIN, MOUSE; EPS15 PROTEIN, RAT; GJA1 PROTEIN, MOUSE; LC3 PROTEIN, RAT; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL COMMUNICATION; CONTROLLED STUDY; HEART CELL CULTURE; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; INTERNALIZATION; ISOLATED HEART; LIGHT CHAIN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN TARGETING; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SIMULATION; UBIQUITINATION; ANIMAL; CELL LINE; GAP JUNCTION; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; WISTAR RAT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CALCIUM-BINDING PROTEINS; CELL LINE; CONNEXIN 43; GAP JUNCTIONS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEOLYSIS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; UBIQUITIN;

EID: 84930798449     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20141370     Document Type: Article

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