Impact of hypoxia, simulated ischemia and reperfusion in HL-1 cells on the expression of FKBP12/FKBP12.6 and intracellular calcium dynamics

Biochemical and Biophysical Research Communications

Volumn 422, Issue 4, 2012, Pages 732-738

  Åström Olsson, Karin ^a   Li, Lizhen ^a   Olofsson, Charlotta S ^b   Borén, Jan ^a   Öhlin, Hans ^c   Grip, Lars ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Ca 2+; FKBP12 FKBP12.6; HL 1 cells; Viability

Indexed keywords

CAFFEINE; CALCIUM BINDING PROTEIN; CALCIUM ION; FURA 2; MESSENGER RNA; PROTEIN FKBP12; PROTEIN FKBP12.6; REACTIVE OXYGEN METABOLITE; TRYPAN BLUE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CELL LYSATE; CELL STRAIN HL 1; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HYPOXIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; SIMULATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CALCIUM; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; CYTOSOL; MICE; MYOCARDIAL REPERFUSION INJURY; OXYGEN; REACTIVE OXYGEN SPECIES; TACROLIMUS BINDING PROTEIN 1A; TACROLIMUS BINDING PROTEINS;

EID: 84862296457     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.05.071     Document Type: Article

References (23)

1. The GUSTO investigators An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. N. Engl. J. Med. 1993, 329:673-682.
2. Braunwald E., Kloner R.A. Myocardial reperfusion: a double-edged sword. J. Clin. Invest. 1985, 76:1713-1719.
3. Yellon D.M., Hausenloy D.J. Myocardial reperfusion injury. N. Engl. J. Med. 2007, 357:1121-1135.
4. Silverman H.S., Stern M.D. Ionic basis of ischaemic cardiac injury: insights from cellular studies. Cardiovasc. Res. 1994, 5:581-597.
5. Bolli R. Basic and clinical aspects of myocardial stunning. Prog. Cardiovasc. Dis. 1998, 40:477-517.
6. Åström-Olsson K., Karlsson L., Mattsson Hultén L., et al. Myocardial release of FKBP12 and increased production of FKBP12.6 in ischemia and reperfusion, experimental models. Biochem. Biophysical. Res. Comm. 2009, 390:1299-1304.
7. Claycomb W.C., Lanson N.A., Stallworth B., et al. HL-1-cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc. Natl. Acad. Sci. USA 1998, 95:2979-2984.
8. + exchange. Am. J. Physiol. Cell Physiol. 2009, 296:C1227-1242.
9. Cicconi S., Ventura N., Pastore D., et al. Characterization of apoptosis signal transduction pathways in HL-5 cardiomyocytes exposed to ischemia/reperfusion oxidative stress model. J. Cell Physiol. 2003, 195:27-37.
10. Szabo S.E., Monroe S.L., Fiorino S., et al. Evaluation of an automated instrument for viability and concentration measurements of cryopreserved hematopoietic cells. Lab. Hematol. 2004, 10:109-111.
11. Yang Y., Fan W., Zhu L., et al. Effects of hypoxia on mRNA expression of housekeeping genes in rat brain tissue and primary cultured neural cells. Front. Med. China 2008, 3:239-243.
12. Knight R.J., Kofoed K.F., Schelbert H.R., et al. Inhibition of glyceraldehyde-3-phosphate dehydrogenase in post-ischaemic myocardium. Cardiovasc. Res. 1996, 32:1016-1023.
13. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 1985, 260:3440-3450.
14. 2+ currents and the size of the readily releasable granule pool in mouse pancreatic β-cells. J. Physiol. 2004, 557:935-948.
15. Steenbergen C., Murphy E., Levy L., et al. Elevation in cytosolic free calcium concentration early in myocardial ischemia in perfused rat heart. Circ. Res. 1987, 60:700-707.
16. Stamm C., Friehs I., Choi Y.H., et al. Cytosolic calcium in the ischemic rabbit heart: assessment by pH- and temperature-adjusted rhod-2 spectrofluorometry. Cardiovasc. Res. 2003, 59:695-704.
17. 2+ after perfusion arrest in isolated, perfused mouse heart. Cardiovasc. Res. 2006, 70:335-345.
18. 2+ exchange and ryanodine receptor activities in ischemic-reperfusion. Am. J. Physiol. Cell Physiol. 2007, 292:C2046-2056.
19. 2+ depletion of the sarcoplasmic reticulum at the onset of reperfusion. Cardiovasc. Res. 2010, 85:671-680.
20. 2+/calmodulin-dependent protein kinase II. Am. J. Physiol. 2008, 295:H1669-H1683.
21. 2+, and adenine nucleotides under normal and simulated ischemic conditions. Circ. Res. 1996, 79:1100-1109.
22. Wehrens X.H.T., Lehnart S.E., Marks A.R. Intracellular calcium release and cardiac disease. Annu. Rev. Physiol. 2005, 67:69-98.
23. Lehnart S.E., Marks A.R. Regulation of ryanodine receptors in the heart. Circ. Res. 2007, 101:746-749.