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Angewandte Chemie - International Edition

Volumn 54, Issue 28, 2015, Pages 8154-8159

Pim Kinase Inhibitors Evaluated with a Single-Molecule Engineered Nanopore Sensor

(4) Harrington, Leon a,b,c Alexander, Leila T b,d Knapp, Stefan b Bayley, Hagan a

a UNIVERSITY OF OXFORD (United Kingdom)

b UNIVERSITY OF OXFORD (United Kingdom)

c MAX PLANCK INSTITUTE OF BIOCHEMISTRY (Germany)

d ETH ZURICH (Switzerland)

Author keywords

drug discovery; inhibitors; protein kinases; screening; single molecule studies

Indexed keywords

BINS; CORROSION INHIBITORS; ENZYME INHIBITION; MOLECULES; NANOPORES; PEPTIDES; PROTEINS; SCREENING;

DIFFERENTIAL SCANNING FLUORIMETRY; DRUG DISCOVERY; INHIBITION CONSTANTS; KINASE INHIBITORS; POTENT INHIBITOR; PROTEIN KINASE; SINGLE-MOLECULE STUDIES; THERAPEUTIC TARGETS;

ENZYMES;

PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN KINASE PIM 1; PROTO-ONCOGENE PROTEINS PIM;

ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DEVELOPMENT; METABOLISM; NANOPORE;

DRUG DISCOVERY; MOLECULAR STRUCTURE; NANOPORES; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-PIM-1;

EID: 84930741617 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201503141 Document Type: Article

Times cited : (28)

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