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Volumn 13, Issue 5, 2015, Pages

Huntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKC

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; PROTEIN KINASE C ALPHA; PROTEINASE ACTIVATED RECEPTOR 3; RAB11 PROTEIN; RAB11A PROTEIN; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; HTT PROTEIN, MOUSE; NERVE PROTEIN; NUCLEAR PROTEIN; PARD3 PROTEIN, MOUSE; PKC-3 PROTEIN; PROTEIN KINASE C; RAB PROTEIN;

EID: 84930664089     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1002142     Document Type: Article
Times cited : (36)

References (63)
  • 1
    • 79551700457 scopus 로고    scopus 로고
    • Mostov KE Molecular regulation of lumen morphogenesis
    • Datta A, Bryant DM, Mostov KE Molecular regulation of lumen morphogenesis. Curr Biol. 2011;21: R126–136. doi: 10.1016/j.cub.2010.12.003 21300279
    • (2011) Curr Biol , vol.21 , pp. 126-136
    • Datta, A.1    Bryant, D.M.2
  • 2
    • 70450128390 scopus 로고    scopus 로고
    • Rodriguez-Boulan E Apical trafficking in epithelial cells: signals, clusters and motors
    • Weisz OA, Rodriguez-Boulan E Apical trafficking in epithelial cells: signals, clusters and motors. J Cell Sci. 2009;122: 4253–4266. doi: 10.1242/jcs.032615 19923269
    • (2009) J Cell Sci , vol.122 , pp. 4253-4266
    • Weisz, O.A.1
  • 3
    • 80053329220 scopus 로고    scopus 로고
    • Martin-Belmonte F Divide and polarize: recent advances in the molecular mechanism regulating epithelial tubulogenesis
    • Rodriguez-Fraticelli AE, Galvez-Santisteban M, Martin-Belmonte F Divide and polarize: recent advances in the molecular mechanism regulating epithelial tubulogenesis. Curr Opin Cell Biol. 2011;23: 638–646. doi: 10.1016/j.ceb.2011.07.002 21807489
    • (2011) Curr Opin Cell Biol , vol.23 , pp. 638-646
    • Rodriguez-Fraticelli, A.E.1    Galvez-Santisteban, M.2
  • 4
    • 41549086164 scopus 로고    scopus 로고
    • Regulation of cell polarity during epithelial morphogenesis
    • Martin-Belmonte F, Mostov K, Regulation of cell polarity during epithelial morphogenesis. Curr Opin Cell Biol. 2008;20: 227–234. doi: 10.1016/j.ceb.2008.01.001 18282696
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 227-234
    • Martin-Belmonte, F.1    Mostov, K.2
  • 5
    • 10844272528 scopus 로고    scopus 로고
    • PDZ domain polarity complexes
    • Bilder D, PDZ domain polarity complexes. Curr Biol. 2003;13: R661–662. 12956964
    • (2003) Curr Biol , vol.13 , pp. 661-662
    • Bilder, D.1
  • 6
    • 0037711781 scopus 로고    scopus 로고
    • Claudin complexities at the apical junctional complex
    • Tepass U, Claudin complexities at the apical junctional complex. Nat Cell Biol. 2003;5: 595–597. 12833061
    • (2003) Nat Cell Biol , vol.5 , pp. 595-597
    • Tepass, U.1
  • 7
    • 30844456421 scopus 로고    scopus 로고
    • PAR proteins and the cytoskeleton: a marriage of equals
    • Munro EM, PAR proteins and the cytoskeleton: a marriage of equals. Curr Opin Cell Biol. 2006;18: 86–94. 16364625
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 86-94
    • Munro, E.M.1
  • 8
    • 0032487494 scopus 로고    scopus 로고
    • An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
    • Izumi Y, Hirose T, Tamai Y, Hirai S, Nagashima Y, et al. An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3. J Cell Biol. 1998;143: 95–106. 9763423
    • (1998) J Cell Biol , vol.143 , pp. 95-106
    • Izumi, Y.1    Hirose, T.2    Tamai, Y.3    Hirai, S.4    Nagashima, Y.5
  • 9
    • 14744289370 scopus 로고    scopus 로고
    • Par-3 controls tight junction assembly through the Rac exchange factor Tiam1
    • Chen X, Macara IG, Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. Nat Cell Biol. 2005;7: 262–269. 15723052
    • (2005) Nat Cell Biol , vol.7 , pp. 262-269
    • Chen, X.1    Macara, I.G.2
  • 10
    • 33846270032 scopus 로고    scopus 로고
    • PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42
    • Martin-Belmonte F, Gassama A, Datta A, Yu W, Rescher U, et al. PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. Cell. 2007;128: 383–397. 17254974
    • (2007) Cell , vol.128 , pp. 383-397
    • Martin-Belmonte, F.1    Gassama, A.2    Datta, A.3    Yu, W.4    Rescher, U.5
  • 11
    • 0037230118 scopus 로고    scopus 로고
    • PAR-1 is required for morphogenesis of the Caenorhabditis elegans vulva
    • Hurd DD, Kemphues KJ, PAR-1 is required for morphogenesis of the Caenorhabditis elegans vulva. Dev Biol. 2003;253: 54–65. 12490197
    • (2003) Dev Biol , vol.253 , pp. 54-65
    • Hurd, D.D.1    Kemphues, K.J.2
  • 12
    • 1542283794 scopus 로고    scopus 로고
    • CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells
    • Lemmers C, Michel D, Lane-Guermonprez L, Delgrossi MH, Medina E, et al. CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells. Mol Biol Cell. 2004;15: 1324–1333. 14718572
    • (2004) Mol Biol Cell , vol.15 , pp. 1324-1333
    • Lemmers, C.1    Michel, D.2    Lane-Guermonprez, L.3    Delgrossi, M.H.4    Medina, E.5
  • 13
    • 13444267951 scopus 로고    scopus 로고
    • Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae
    • Betschinger J, Eisenhaber F, Knoblich JA, Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae. Curr Biol. 2005;15: 276–282. 15694314
    • (2005) Curr Biol , vol.15 , pp. 276-282
    • Betschinger, J.1    Eisenhaber, F.2    Knoblich, J.A.3
  • 14
    • 24144443830 scopus 로고    scopus 로고
    • The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila
    • Harris TJ, Peifer M, The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila. J Cell Biol. 2005;170: 813–823. 16129788
    • (2005) J Cell Biol , vol.170 , pp. 813-823
    • Harris, T.J.1    Peifer, M.2
  • 15
    • 67149106023 scopus 로고    scopus 로고
    • The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis
    • McCaffrey LM, Macara IG, The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis. Genes Dev. 2009;23: 1450–1460. doi: 10.1101/gad.1795909 19528321
    • (2009) Genes Dev , vol.23 , pp. 1450-1460
    • McCaffrey, L.M.1    Macara, I.G.2
  • 17
    • 79952588402 scopus 로고    scopus 로고
    • Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization
    • Roland JT, Bryant DM, Datta A, Itzen A, Mostov KE, et al. Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization. Proc Natl Acad Sci U S A. 2011;108: 2789–2794. doi: 10.1073/pnas.1010754108 21282656
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 2789-2794
    • Roland, J.T.1    Bryant, D.M.2    Datta, A.3    Itzen, A.4    Mostov, K.E.5
  • 18
    • 77950877404 scopus 로고    scopus 로고
    • Coordination of Rab8 and Rab11 in primary ciliogenesis
    • Knodler A, Feng S, Zhang J, Zhang X, Das A, et al. Coordination of Rab8 and Rab11 in primary ciliogenesis. Proc Natl Acad Sci U S A. 2010;107: 6346–6351. doi: 10.1073/pnas.1002401107 20308558
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 6346-6351
    • Knodler, A.1    Feng, S.2    Zhang, J.3    Zhang, X.4    Das, A.5
  • 19
    • 0028803757 scopus 로고
    • A huntingtin-associated protein enriched in brain with implications for pathology
    • Li XJ, Li SH, Sharp AH, Nucifora FC, Jr.Schilling G, et al. A huntingtin-associated protein enriched in brain with implications for pathology. Nature. 1995;378: 398–402. 7477378
    • (1995) Nature , vol.378 , pp. 398-402
    • Li, X.J.1    Li, S.H.2    Sharp, A.H.3    Nucifora, F.C.4    Schilling, G.5
  • 20
    • 33645642673 scopus 로고    scopus 로고
    • Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons
    • McGuire JR, Rong J, Li SH, Li XJ, Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons. J Biol Chem. 2006;281: 3552–3559. 16339760
    • (2006) J Biol Chem , vol.281 , pp. 3552-3559
    • McGuire, J.R.1    Rong, J.2    Li, S.H.3    Li, X.J.4
  • 21
    • 0032519646 scopus 로고    scopus 로고
    • Interaction of huntingtin-associated protein with dynactin P150Glued
    • Li SH, Gutekunst CA, Hersch SM, Li XJ, Interaction of huntingtin-associated protein with dynactin P150Glued. J Neurosci. 1998;18: 1261–1269. 9454836
    • (1998) J Neurosci , vol.18 , pp. 1261-1269
    • Li, S.H.1    Gutekunst, C.A.2    Hersch, S.M.3    Li, X.J.4
  • 22
    • 0141750470 scopus 로고    scopus 로고
    • Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
    • Gunawardena S, Her LS, Brusch RG, Laymon RA, Niesman IR, et al. Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron. 2003;40: 25–40. 14527431
    • (2003) Neuron , vol.40 , pp. 25-40
    • Gunawardena, S.1    Her, L.S.2    Brusch, R.G.3    Laymon, R.A.4    Niesman, I.R.5
  • 24
    • 3142636768 scopus 로고    scopus 로고
    • Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
    • Gauthier LR, Charrin BC, Borrell-Pages M, Dompierre JP, Rangone H, et al. Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell. 2004;118: 127–138. 15242649
    • (2004) Cell , vol.118 , pp. 127-138
    • Gauthier, L.R.1    Charrin, B.C.2    Borrell-Pages, M.3    Dompierre, J.P.4    Rangone, H.5
  • 25
    • 55349084412 scopus 로고    scopus 로고
    • A function of huntingtin in guanine nucleotide exchange on Rab11
    • Li X, Sapp E, Valencia A, Kegel KB, Qin ZH, et al. A function of huntingtin in guanine nucleotide exchange on Rab11. Neuroreport. 2008;19: 1643–1647. doi: 10.1097/WNR.0b013e328315cd4c 18845944
    • (2008) Neuroreport , vol.19 , pp. 1643-1647
    • Li, X.1    Sapp, E.2    Valencia, A.3    Kegel, K.B.4    Qin, Z.H.5
  • 26
    • 77955436243 scopus 로고    scopus 로고
    • Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis
    • Godin JD, Colombo K, Molina-Calavita M, Keryer G, Zala D, et al. Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis. Neuron. 2010;67: 392–406. doi: 10.1016/j.neuron.2010.06.027 20696378
    • (2010) Neuron , vol.67 , pp. 392-406
    • Godin, J.D.1    Colombo, K.2    Molina-Calavita, M.3    Keryer, G.4    Zala, D.5
  • 27
    • 84877740982 scopus 로고    scopus 로고
    • Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis
    • Ben M'barek K, Pla P, Orvoen S, Benstaali C, Godin JD, et al. Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis. J Neurosci. 2013;33: 8608–8620. doi: 10.1523/JNEUROSCI.5110-12.2013 23678106
    • (2013) J Neurosci , vol.33 , pp. 8608-8620
    • Ben M'barek, K.1    Pla, P.2    Orvoen, S.3    Benstaali, C.4    Godin, J.D.5
  • 28
    • 80555136825 scopus 로고    scopus 로고
    • Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease
    • Keryer G, Pineda JR, Liot G, Kim J, Dietrich P, et al. Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease. J Clin Invest. 2011;121: 4372–4382. doi: 10.1172/JCI57552 21985783
    • (2011) J Clin Invest , vol.121 , pp. 4372-4382
    • Keryer, G.1    Pineda, J.R.2    Liot, G.3    Kim, J.4    Dietrich, P.5
  • 29
    • 84873322617 scopus 로고    scopus 로고
    • The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling
    • Moreira Sousa C, McGuire JR, Thion MS, Gentien D, de la Grange P, et al. The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling. EMBO Mol Med. 2013;5: 309–325. doi: 10.1002/emmm.201201546 23300147
    • (2013) EMBO Mol Med , vol.5 , pp. 309-325
    • Moreira Sousa, C.1    McGuire, J.R.2    Thion, M.S.3    Gentien, D.4    de la Grange, P.5
  • 30
    • 84898443684 scopus 로고    scopus 로고
    • Huntingtin regulates mammary stem cell division and differentiation
    • Elias S, Thion MS, Yu H, Sousa CM, Lasgi C, et al. Huntingtin regulates mammary stem cell division and differentiation. Stem Cell Reports. 2014;2: 491–506. doi: 10.1016/j.stemcr.2014.02.011 24749073
    • (2014) Stem Cell Reports , vol.2 , pp. 491-506
    • Elias, S.1    Thion, M.S.2    Yu, H.3    Sousa, C.M.4    Lasgi, C.5
  • 31
    • 0033757718 scopus 로고    scopus 로고
    • Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice
    • Dragatsis I, Levine MS, Zeitlin S, Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice. Nat Genet. 2000;26: 300–306. 11062468
    • (2000) Nat Genet , vol.26 , pp. 300-306
    • Dragatsis, I.1    Levine, M.S.2    Zeitlin, S.3
  • 33
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath J, Muthuswamy SK, Brugge JS, Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods. 2003;30: 256–268. 12798140
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 34
    • 84864812813 scopus 로고    scopus 로고
    • SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling
    • Jahchan NS, Wang D, Bissell MJ, Luo K, SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling. Development. 2012;139: 3147–3156. doi: 10.1242/dev.079616 22833129
    • (2012) Development , vol.139 , pp. 3147-3156
    • Jahchan, N.S.1    Wang, D.2    Bissell, M.J.3    Luo, K.4
  • 35
    • 0026760941 scopus 로고
    • Cytoplasmic dynein participates in the centrosomal localization of the Golgi complex
    • Corthesy-Theulaz I, Pauloin A, Pfeffer SR, Cytoplasmic dynein participates in the centrosomal localization of the Golgi complex. J Cell Biol. 1992;118: 1333–1345. 1387874
    • (1992) J Cell Biol , vol.118 , pp. 1333-1345
    • Corthesy-Theulaz, I.1    Pauloin, A.2    Pfeffer, S.R.3
  • 36
    • 84863833900 scopus 로고    scopus 로고
    • Network organization of the huntingtin proteomic interactome in mammalian brain
    • Shirasaki DI, Greiner ER, Al-Ramahi I, Gray M, Boontheung P, et al. Network organization of the huntingtin proteomic interactome in mammalian brain. Neuron. 2012;75: 41–57. doi: 10.1016/j.neuron.2012.05.024 22794259
    • (2012) Neuron , vol.75 , pp. 41-57
    • Shirasaki, D.I.1    Greiner, E.R.2    Al-Ramahi, I.3    Gray, M.4    Boontheung, P.5
  • 37
    • 84871712311 scopus 로고    scopus 로고
    • An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium
    • Akhtar N, Streuli CH, An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium. Nat Cell Biol. 2013;15: 17–27. 23263281
    • (2013) Nat Cell Biol , vol.15 , pp. 17-27
    • Akhtar, N.1    Streuli, C.H.2
  • 38
    • 77954905229 scopus 로고    scopus 로고
    • ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development
    • Sottocornola R, Royer C, Vives V, Tordella L, Zhong S, et al. ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development. Dev Cell. 2010;19: 126–137. doi: 10.1016/j.devcel.2010.06.003 20619750
    • (2010) Dev Cell , vol.19 , pp. 126-137
    • Sottocornola, R.1    Royer, C.2    Vives, V.3    Tordella, L.4    Zhong, S.5
  • 39
    • 67449146294 scopus 로고    scopus 로고
    • Culturing MDCK cells in three dimensions for analyzing intracellular dynamics
    • Elia N, Lippincott-Schwartz J, Culturing MDCK cells in three dimensions for analyzing intracellular dynamics. Curr Protoc Cell Biol. 2009;Chapter 4: Unit 4 22.
    • (2009) Curr Protoc Cell Biol
    • Elia, N.1    Lippincott-Schwartz, J.2
  • 40
    • 77953846289 scopus 로고    scopus 로고
    • pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking
    • Pardo R, Molina-Calavita M, Poizat G, Keryer G, Humbert S, et al. pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking. Mol Brain. 2010;3: 17. doi: 10.1186/1756-6606-3-17 20515468
    • (2010) Mol Brain , vol.3 , pp. 17
    • Pardo, R.1    Molina-Calavita, M.2    Poizat, G.3    Keryer, G.4    Humbert, S.5
  • 41
    • 49149112606 scopus 로고    scopus 로고
    • Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons
    • Colin E, Zala D, Liot G, Rangone H, Borrell-Pages M, et al. Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons. EMBO J. 2008;27: 2124–2134. doi: 10.1038/emboj.2008.133 18615096
    • (2008) EMBO J , vol.27 , pp. 2124-2134
    • Colin, E.1    Zala, D.2    Liot, G.3    Rangone, H.4    Borrell-Pages, M.5
  • 42
    • 34447519003 scopus 로고    scopus 로고
    • The Rab8 GTPase regulates apical protein localization in intestinal cells
    • Sato T, Mushiake S, Kato Y, Sato K, Sato M, et al. The Rab8 GTPase regulates apical protein localization in intestinal cells. Nature. 2007;448: 366–369. 17597763
    • (2007) Nature , vol.448 , pp. 366-369
    • Sato, T.1    Mushiake, S.2    Kato, Y.3    Sato, K.4    Sato, M.5
  • 43
    • 79953293527 scopus 로고    scopus 로고
    • Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis
    • Durgan J, Kaji N, Jin D, Hall A, Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis. J Biol Chem. 2011;286: 12461–12474. doi: 10.1074/jbc.M110.174235 21300793
    • (2011) J Biol Chem , vol.286 , pp. 12461-12474
    • Durgan, J.1    Kaji, N.2    Jin, D.3    Hall, A.4
  • 44
    • 67349124434 scopus 로고    scopus 로고
    • Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: failure of Stat5 activation and functional differentiation in the absence of Elf5
    • Choi YS, Chakrabarti R, Escamilla-Hernandez R, Sinha S, Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: failure of Stat5 activation and functional differentiation in the absence of Elf5. Dev Biol. 2009;329: 227–241. doi: 10.1016/j.ydbio.2009.02.032 19269284
    • (2009) Dev Biol , vol.329 , pp. 227-241
    • Choi, Y.S.1    Chakrabarti, R.2    Escamilla-Hernandez, R.3    Sinha, S.4
  • 45
    • 24144477936 scopus 로고    scopus 로고
    • Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membrane
    • Langevin J, Morgan MJ, Sibarita JB, Aresta S, Murthy M, et al. Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membrane. Dev Cell. 2005;9: 365–376. 16224820
    • (2005) Dev Cell , vol.9 , pp. 365-376
    • Langevin, J.1    Morgan, M.J.2    Sibarita, J.B.3    Aresta, S.4    Murthy, M.5
  • 46
    • 77954886545 scopus 로고    scopus 로고
    • Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease
    • Godin JD, Poizat G, Hickey MA, Maschat F, Humbert S, Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease. EMBO J. 2010;29: 2433–2445. doi: 10.1038/emboj.2010.117 20531388
    • (2010) EMBO J , vol.29 , pp. 2433-2445
    • Godin, J.D.1    Poizat, G.2    Hickey, M.A.3    Maschat, F.4    Humbert, S.5
  • 47
    • 78049255724 scopus 로고    scopus 로고
    • Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins
    • Hao Y, Du Q, Chen X, Zheng Z, Balsbaugh JL, et al. Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Curr Biol. 2010;20: 1809–1818. doi: 10.1016/j.cub.2010.09.032 20933426
    • (2010) Curr Biol , vol.20 , pp. 1809-1818
    • Hao, Y.1    Du, Q.2    Chen, X.3    Zheng, Z.4    Balsbaugh, J.L.5
  • 48
    • 84896691702 scopus 로고    scopus 로고
    • Rab11 endosomes contribute to mitotic spindle organization and orientation
    • Hehnly H, Doxsey S, Rab11 endosomes contribute to mitotic spindle organization and orientation. Dev Cell. 2014;28: 497–507. doi: 10.1016/j.devcel.2014.01.014 24561039
    • (2014) Dev Cell , vol.28 , pp. 497-507
    • Hehnly, H.1    Doxsey, S.2
  • 49
    • 84867169653 scopus 로고    scopus 로고
    • In-vivo evidence for the disruption of Rab11 vesicle transport by loss of huntingtin
    • Power D, Srinivasan S, Gunawardena S, In-vivo evidence for the disruption of Rab11 vesicle transport by loss of huntingtin. Neuroreport. 2012;23: 970–977. doi: 10.1097/WNR.0b013e328359d990 23032403
    • (2012) Neuroreport , vol.23 , pp. 970-977
    • Power, D.1    Srinivasan, S.2    Gunawardena, S.3
  • 50
    • 32644434386 scopus 로고    scopus 로고
    • Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease
    • Pal A, Severin F, Lommer B, Shevchenko A, Zerial M, Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease. J Cell Biol. 2006;172: 605–618. 16476778
    • (2006) J Cell Biol , vol.172 , pp. 605-618
    • Pal, A.1    Severin, F.2    Lommer, B.3    Shevchenko, A.4    Zerial, M.5
  • 51
    • 0034649661 scopus 로고    scopus 로고
    • FIP-2, a coiled-coil protein, links huntingtin to Rab8 and modulates cellular morphogenesis
    • Hattula K, Peranen J, FIP-2, a coiled-coil protein, links huntingtin to Rab8 and modulates cellular morphogenesis. Curr Biol. 2000;24: 1603–1606. 11137014
    • (2000) Curr Biol , vol.24 , pp. 1603-1606
    • Hattula, K.1    Peranen, J.2
  • 53
    • 44449152002 scopus 로고    scopus 로고
    • The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors
    • Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, et al. The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors. Hum Pathol. 2008;39: 824–831. doi: 10.1016/j.humpath.2007.11.001 18538170
    • (2008) Hum Pathol , vol.39 , pp. 824-831
    • Kojima, Y.1    Akimoto, K.2    Nagashima, Y.3    Ishiguro, H.4    Shirai, S.5
  • 55
    • 37249071974 scopus 로고    scopus 로고
    • Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells
    • Sfakianos J, Togawa A, Maday S, Hull M, Pypaert M, et al. Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells. J Cell Biol. 2007;179: 1133–1140. 18070914
    • (2007) J Cell Biol , vol.179 , pp. 1133-1140
    • Sfakianos, J.1    Togawa, A.2    Maday, S.3    Hull, M.4    Pypaert, M.5
  • 56
    • 0025129726 scopus 로고
    • Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
    • Soule HD, Maloney TM, Wolman SR, Peterson WD, Jr.Brenz R, et al. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res. 1990;50: 6075–6086. 1975513
    • (1990) Cancer Res , vol.50 , pp. 6075-6086
    • Soule, H.D.1    Maloney, T.M.2    Wolman, S.R.3    Peterson, W.D.4    Brenz, R.5
  • 57
    • 77951174042 scopus 로고    scopus 로고
    • LGN regulates mitotic spindle orientation during epithelial morphogenesis
    • Zheng Z, Zhu H, Wan Q, Liu J, Xiao Z, et al. LGN regulates mitotic spindle orientation during epithelial morphogenesis. J Cell Biol. 2010;189: 275–288. doi: 10.1083/jcb.200910021 20385777
    • (2010) J Cell Biol , vol.189 , pp. 275-288
    • Zheng, Z.1    Zhu, H.2    Wan, Q.3    Liu, J.4    Xiao, Z.5
  • 58
    • 65249131740 scopus 로고    scopus 로고
    • Sustained effects of nonallele-specific Huntingtin silencing
    • Drouet V, Perrin V, Hassig R, Dufour N, Auregan G, et al. Sustained effects of nonallele-specific Huntingtin silencing. Ann Neurol. 2009;65: 276–285. doi: 10.1002/ana.21569 19334076
    • (2009) Ann Neurol , vol.65 , pp. 276-285
    • Drouet, V.1    Perrin, V.2    Hassig, R.3    Dufour, N.4    Auregan, G.5
  • 59
    • 84876800737 scopus 로고    scopus 로고
    • Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium
    • Meier-Abt F, Milani E, Roloff T, Brinkhaus H, Duss S, et al. Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium. Breast Cancer Res. 2013;15: R36. doi: 10.1186/bcr3419 23621987
    • (2013) Breast Cancer Res , vol.15 , pp. 36
    • Meier-Abt, F.1    Milani, E.2    Roloff, T.3    Brinkhaus, H.4    Duss, S.5
  • 60
    • 84871240614 scopus 로고    scopus 로고
    • Atbf1 regulates pubertal mammary gland development likely by inhibiting the pro-proliferative function of estrogen-ER signaling
    • Li M, Fu X, Ma G, Sun X, Dong X, et al. Atbf1 regulates pubertal mammary gland development likely by inhibiting the pro-proliferative function of estrogen-ER signaling. PLoS One. 2012;7: e51283. doi: 10.1371/journal.pone.0051283 23251482
    • (2012) PLoS One , vol.7 , pp. 51283
    • Li, M.1    Fu, X.2    Ma, G.3    Sun, X.4    Dong, X.5
  • 61
    • 30144432901 scopus 로고    scopus 로고
    • Purification and unique properties of mammary epithelial stem cells
    • Stingl J, Eirew P, Ricketson I, Shackleton M, Vaillant F, et al. Purification and unique properties of mammary epithelial stem cells. Nature. 2006;439: 993–997. 16395311
    • (2006) Nature , vol.439 , pp. 993-997
    • Stingl, J.1    Eirew, P.2    Ricketson, I.3    Shackleton, M.4    Vaillant, F.5
  • 62
    • 44649150257 scopus 로고    scopus 로고
    • Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells
    • Taddei I, Deugnier MA, Faraldo MM, Petit V, Bouvard D, et al. Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells. Nat Cell Biol. 2008;10: 716–722. doi: 10.1038/ncb1734 18469806
    • (2008) Nat Cell Biol , vol.10 , pp. 716-722
    • Taddei, I.1    Deugnier, M.A.2    Faraldo, M.M.3    Petit, V.4    Bouvard, D.5
  • 63
    • 54849422301 scopus 로고    scopus 로고
    • Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner
    • Benn CL, Sun T, Sadri-Vakili G, McFarland KN, DiRocco DP, et al. Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner. J Neurosci. 2008;28: 10720–10733. doi: 10.1523/JNEUROSCI.2126-08.2008 18923047
    • (2008) J Neurosci , vol.28 , pp. 10720-10733
    • Benn, C.L.1    Sun, T.2    Sadri-Vakili, G.3    McFarland, K.N.4    DiRocco, D.P.5


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