Emodin ameliorates LPS-induced acute lung injury, involving the inactivation of NF-κB in mice

International Journal of Molecular Sciences

Volumn 15, Issue 11, 2014, Pages 19355-19368

  Xiao, Min ^a   Zhu, Tao ^a   Zhang, Wei ^b   Wang, Tao ^a   Shen, Yong Chun ^a   Wan, Qiong Fang ^a   Wen, Fu Qiang ^a  

^a SICHUAN UNIVERSITY   (China)

^b CHENGDU MEDICAL COLLEGE   (China)

Author keywords

Acute lung injury (ALI); Acute respiratory distress syndrome (ARDS); E selectin; Emodin; Lipopolysaccharide (LPS); MCP 1; Nuclear factor B (NF B)

Indexed keywords

EMODIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; LIPOPOLYSACCHARIDE; PEROXIDASE; PROTEIN KINASE INHIBITOR;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL MODEL; ARTICLE; ASSESSMENT OF HUMANS; CONTROLLED STUDY; DNA BINDING; DRUG MECHANISM; ENZYME ACTIVITY; LUNG EDEMA; LUNG INJURY SCORE; LUNG LAVAGE; MACROPHAGE; MALE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; WESTERN BLOTTING; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; CHEMICALLY INDUCED; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION; GENETICS; METABOLISM; PATHOLOGY; PULMONARY EDEMA; SIGNAL TRANSDUCTION;

MUS;

ACUTE LUNG INJURY; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINE CCL2; E-SELECTIN; EMODIN; ENZYME ACTIVATION; GENE EXPRESSION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MALE; MICE; NF-KAPPA B; PEROXIDASE; PNEUMONIA; PROTEIN KINASE INHIBITORS; PULMONARY EDEMA; SIGNAL TRANSDUCTION;

EID: 84930653038     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms151119355     Document Type: Article

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