메뉴 건너뛰기




Volumn 125, Issue 8, 2012, Pages 1457-1464

Rosuvastatin attenuates mucus secretion in a murine model of chronic asthma by inhibiting the gamma-aminobutyric acid type A receptor

Author keywords

Airway remodeling; Asthma; Gamma aminobutyric acid type A receptor 2; Mucus; Rosuvastatin

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BETA2; BUDESONIDE; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; ROSUVASTATIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84860445793     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2012.08.018     Document Type: Article
Times cited : (34)

References (28)
  • 3
    • 0037246364 scopus 로고    scopus 로고
    • Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling
    • Holgate ST, Peters-Golden M, Panettieri RA, Henderson Jr WR. Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling. J Allergy Clin Immunol 2003; 111 Suppl 1: S18e34. discussion S34-S36.
    • (2003) J Allergy Clin Immunol , vol.111 , Issue.SUPPL. 1
    • Holgate, S.T.1    Peters-Golden, M.2    Panettieri, R.A.3    Henderson, W.R.4
  • 4
    • 34447128711 scopus 로고    scopus 로고
    • A new link to airway obstruction in asthma
    • Corry DB, Kheradmand F. A new link to airway obstruction in asthma. Nat Med 2007; 13: 777-778.
    • (2007) Nat Med , vol.13 , pp. 777-778
    • Corry, D.B.1    Kheradmand, F.2
  • 5
    • 50649121609 scopus 로고    scopus 로고
    • + regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling
    • + regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling. J Allergy Clin Immunol 2008; 122: 617-624.
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 617-624
    • Kearley, J.1    Robinson, D.S.2    Lloyd, C.M.3
  • 7
    • 33747079023 scopus 로고    scopus 로고
    • Potential therapeutic role for statins in respiratory disease
    • Hothersall E, McSharry C, Thomson NC. Potential therapeutic role for statins in respiratory disease. Thorax 2006; 61: 729-734.
    • (2006) Thorax , vol.61 , pp. 729-734
    • Hothersall, E.1    McSharry, C.2    Thomson, N.C.3
  • 8
    • 0035887743 scopus 로고    scopus 로고
    • The functional role of Rho and Rho-associated coiled-coil forming protein kinase in eotaxin signaling of eosinophils
    • Adachi T, Vita R, Sannohe S, Stafford S, Alam R, Kayaba H, et al. The functional role of Rho and Rho-associated coiled-coil forming protein kinase in eotaxin signaling of eosinophils. J Immunol 2001; 167: 4609-4615.
    • (2001) J Immunol , vol.167 , pp. 4609-4615
    • Adachi, T.1    Vita, R.2    Sannohe, S.3    Stafford, S.4    Alam, R.5    Kayaba, H.6
  • 9
    • 33846931592 scopus 로고    scopus 로고
    • Statin use is associated with reduced mortality in COPD
    • Soyseth V, Brekke PH, Smith P, Omland T. Statin use is associated with reduced mortality in COPD. Eur Respir J 2007; 29: 279-283.
    • (2007) Eur Respir J , vol.29 , pp. 279-283
    • Soyseth, V.1    Brekke, P.H.2    Smith, P.3    Omland, T.4
  • 10
    • 49349115994 scopus 로고    scopus 로고
    • Statins may reduce episodes of exacerbation and the requirement for intubation in patients with COPD: Evidence from a retrospective cohort study
    • Blamoun AI, Batty GN, DeBari VA, Rashid AO, Sheikh M, Khan MA. Statins may reduce episodes of exacerbation and the requirement for intubation in patients with COPD: evidence from a retrospective cohort study. Int J Clin Pract 2008; 62: 1373-1378.
    • (2008) Int J Clin Pract , vol.62 , pp. 1373-1378
    • Blamoun, A.I.1    Batty, G.N.2    Debari, V.A.3    Rashid, A.O.4    Sheikh, M.5    Khan, M.A.6
  • 11
    • 1342282244 scopus 로고    scopus 로고
    • A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma
    • McKay A, Leung BP, McInnes IB, Thomson NC, Liew FY. A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. J Immunol 2004; 172: 2903-2908.
    • (2004) J Immunol , vol.172 , pp. 2903-2908
    • McKay, A.1    Leung, B.P.2    McInnes, I.B.3    Thomson, N.C.4    Liew, F.Y.5
  • 13
    • 2642536741 scopus 로고    scopus 로고
    • Inflammation, immunity, and HMG-CoA reductase inhibitors: Statins as antiinflammatory agents?
    • Schonbeck U, Libby P. Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents? Circulation 2004; 109: II18-II26.
    • (2004) Circulation , vol.109
    • Schonbeck, U.1    Libby, P.2
  • 14
    • 33645384019 scopus 로고    scopus 로고
    • Effects of statins beyond lipid lowering: Potential for clinical benefits
    • Almuti K, Rimawi R, Spevack D, Ostfeld RJ. Effects of statins beyond lipid lowering: potential for clinical benefits. Int J Cardiol 2006; 109: 7-15.
    • (2006) Int J Cardiol , vol.109 , pp. 7-15
    • Almuti, K.1    Rimawi, R.2    Spevack, D.3    Ostfeld, R.J.4
  • 15
    • 33646354412 scopus 로고    scopus 로고
    • Statin therapy and autoimmune disease: From protein prenylation to immunomodulation
    • Greenwood J, Steinman L, Zamvil SS. Statin therapy and autoimmune disease: from protein prenylation to immunomodulation. Natl Rev 2006; 6: 358-370.
    • (2006) Natl Rev , vol.6 , pp. 358-370
    • Greenwood, J.1    Steinman, L.2    Zamvil, S.S.3
  • 16
    • 57149101949 scopus 로고    scopus 로고
    • Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma
    • Hothersall EJ, Chaudhuri R, McSharry C, Donnelly I, Lafferty J, McMahon AD, et al. Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma. Thorax 2008; 63: 1070-1075.
    • (2008) Thorax , vol.63 , pp. 1070-1075
    • Hothersall, E.J.1    Chaudhuri, R.2    McSharry, C.3    Donnelly, I.4    Lafferty, J.5    McMahon, A.D.6
  • 17
    • 33846338938 scopus 로고    scopus 로고
    • Anti-inflammatory mechanism of simvastatin in mouse allergic asthma model
    • Kim DY, Ryu SY, Lim JE, Lee YS, Ro JY. Anti-inflammatory mechanism of simvastatin in mouse allergic asthma model. Eur J Pharmacol 2007; 557: 76-86.
    • (2007) Eur J Pharmacol , vol.557 , pp. 76-86
    • Kim, D.Y.1    Ryu, S.Y.2    Lim, J.E.3    Lee, Y.S.4    Ro, J.Y.5
  • 18
    • 34447116242 scopus 로고    scopus 로고
    • A GABAergic system in airway epithelium is essential for mucus overproduction in asthma
    • YunYan X, Shuhe W, Mingyao L, Jeremy AH, Jingxin L, William J, et al. A GABAergic system in airway epithelium is essential for mucus overproduction in asthma. Nat Med 2007; 13: 862-867.
    • (2007) Nat Med , vol.13 , pp. 862-867
    • Yunyan, X.1    Shuhe, W.2    Mingyao, L.3    Jeremy, A.H.4    Jingxin, L.5    William, J.6
  • 19
    • 33645984847 scopus 로고    scopus 로고
    • Chlamydia infection induces ICOS ligand-expressing and IL-10-producing dendritic cells that can inhibit airway inflammation and mucus overproduction elicited by allergen challenge in BALB/c mice
    • Han XB, Wang SH, Fan YJ, Yang J, Jiao L, Qiu HY, et al. Chlamydia infection induces ICOS ligand-expressing and IL-10-producing dendritic cells that can inhibit airway inflammation and mucus overproduction elicited by allergen challenge in BALB/c mice. J Immunol 2006; 176: 5232-5239.
    • (2006) J Immunol , vol.176 , pp. 5232-5239
    • Han, X.B.1    Wang, S.H.2    Fan, Y.J.3    Yang, J.4    Jiao, L.5    Qiu, H.Y.6
  • 20
    • 60849111087 scopus 로고    scopus 로고
    • Airway mucus: The good, the bad, the sticky
    • Evans CM, Koo JS. Airway mucus: the good, the bad, the sticky. Pharmacol Ther 2009; 121: 332-348.
    • (2009) Pharmacol Ther , vol.121 , pp. 332-348
    • Evans, C.M.1    Koo, J.S.2
  • 21
    • 0034865645 scopus 로고    scopus 로고
    • GABAergic mechanisms in epilepsy
    • Treiman DM. GABAergic mechanisms in epilepsy. Epilepsia 2001; 42 Suppl 3: 8-12.
    • (2001) Epilepsia , vol.42 , Issue.SUPPL. 3 , pp. 8-12
    • Treiman, D.M.1
  • 23
    • 0035916233 scopus 로고    scopus 로고
    • Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization
    • Crisby M, Nordin-Fredriksson G, Shah PK, Yano J, Zhu J, Nilsson J. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation 2001; 103: 926-933.
    • (2001) Circulation , vol.103 , pp. 926-933
    • Crisby, M.1    Nordin-Fredriksson, G.2    Shah, P.K.3    Yano, J.4    Zhu, J.5    Nilsson, J.6
  • 24
    • 0035173483 scopus 로고    scopus 로고
    • Similar effects of atrovastatin, simvastatin and pravastatin on thrombogenic and inflammatory parameters in patients with hypercholesterolemia
    • Joukhadar C, Klein N, Prinz M, Schrolnberger C, Vukovich T, Wolzt M, et al. Similar effects of atrovastatin, simvastatin and pravastatin on thrombogenic and inflammatory parameters in patients with hypercholesterolemia. Thromb Haemost 2001; 85: 47-51.
    • (2001) Thromb Haemost , vol.85 , pp. 47-51
    • Joukhadar, C.1    Klein, N.2    Prinz, M.3    Schrolnberger, C.4    Vukovich, T.5    Wolzt, M.6
  • 25
    • 0035162266 scopus 로고    scopus 로고
    • Simvastatin has antiinflammatory and anti-atherosclerotic activities independent of plasma cholesterol lowering
    • Sparrow CP, Burton CA, Hernandez M, Mundt S, Hassing H, Patel S, et al. Simvastatin has antiinflammatory and anti-atherosclerotic activities independent of plasma cholesterol lowering. Arterioscler Thromb Vasc Biol 2001; 21: 115-121.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 115-121
    • Sparrow, C.P.1    Burton, C.A.2    Hernandez, M.3    Mundt, S.4    Hassing, H.5    Patel, S.6
  • 26
    • 4544239885 scopus 로고    scopus 로고
    • Biomedicine. Eosinophils in asthma: Remodeling a tangled tale
    • Wills-Karp M, Karp CL. Biomedicine. Eosinophils in asthma: remodeling a tangled tale. Science 2004; 305: 1726-1729.
    • (2004) Science , vol.305 , pp. 1726-1729
    • Wills-Karp, M.1    Karp, C.L.2
  • 27
    • 33644620356 scopus 로고    scopus 로고
    • Respiratory tract mucin genes and mucin glycoproteins in health and disease
    • Rose MC, Voynow JA. Respiratory tract mucin genes and mucin glycoproteins in health and disease. Physiol Rev 2006; 86: 245-278.
    • (2006) Physiol Rev , vol.86 , pp. 245-278
    • Rose, M.C.1    Voynow, J.A.2
  • 28
    • 0032545433 scopus 로고    scopus 로고
    • Requirement for IL-13 independently of IL-4 in experimental asthma
    • Gabriele G, Martha W, Adil EW, Rajeev V, Frank B, Donna MR, et al. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 1998; 282: 2261-2263.
    • (1998) Science , vol.282 , pp. 2261-2263
    • Gabriele, G.1    Martha, W.2    Adil, E.W.3    Rajeev, V.4    Frank, B.5    Donna, M.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.