메뉴 건너뛰기




Volumn 14, Issue 12, 2013, Pages 23581-23596

Protective role of andrographolide in bleomycin-induced pulmonary fibrosis in mice

Author keywords

Alpha smooth muscle actin ( SMA); Andrographolide; Bleomycin (BLM); Nuclear factor b (NF B); Pulmonary fibrosis; Transforming growth factor 1 (TGF 1)

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANDROGRAPHOLIDE; BLEOMYCIN; COLLAGEN; HYDROXYPROLINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; ACTIN; ALPHA-SMOOTH MUSCLE ACTIN, MOUSE; ANTIINFLAMMATORY AGENT; DITERPENE; MESSENGER RNA; PROTEIN BINDING; TRANSFORMING GROWTH FACTOR BETA;

EID: 84889607523     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms141223581     Document Type: Article
Times cited : (49)

References (38)
  • 1
    • 84880088341 scopus 로고    scopus 로고
    • A prospective, non-randomized, no placebo-controlled, phase Ib clinical trial to study the safety of the adipose derived stromal cells-stromal vascular fraction in idiopathic pulmonary fibrosis
    • Tzouvelekis, A.; Paspaliaris, V.; Koliakos, G.; Ntolios, P.; Bouros, E.; Oikonomou, A.; Zissimopoulos, A.; Boussios, N.; Dardzinski, B.; Gritzalis, D. et al. A prospective, non-randomized, no placebo-controlled, phase Ib clinical trial to study the safety of the adipose derived stromal cells-stromal vascular fraction in idiopathic pulmonary fibrosis. J. Transl. Med. 2013, 11, 171.
    • (2013) J. Transl. Med , vol.11 , pp. 171
    • Tzouvelekis, A.1    Paspaliaris, V.2    Koliakos, G.3    Ntolios, P.4    Bouros, E.5    Oikonomou, A.6    Zissimopoulos, A.7    Boussios, N.8    Dardzinski, B.9    Gritzalis, D.10
  • 2
    • 84880086518 scopus 로고    scopus 로고
    • IPFnet investigators. Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trials
    • Collard, H.R.; Yow, E.; Richeldi, L.; Anstrom, K.J.; Glazer, C. IPFnet investigators. Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trials. Respir. Res. 2013, 14, 73.
    • (2013) Respir. Res , vol.14 , pp. 73
    • Collard, H.R.1    Yow, E.2    Richeldi, L.3    Anstrom, K.J.4    Glazer, C.5
  • 3
    • 84879286188 scopus 로고    scopus 로고
    • Reducing lung function decline in patients with idiopathic pulmonary fibrosis: Potential of nintedanib
    • Woodcock, H.V.; Molyneaux, P.L.; Maher, T.M. Reducing lung function decline in patients with idiopathic pulmonary fibrosis: Potential of nintedanib. Drug Des. Dev. Ther. 2013, 7, 503-510.
    • (2013) Drug Des. Dev. Ther , vol.7 , pp. 503-510
    • Woodcock, H.V.1    Molyneaux, P.L.2    Maher, T.M.3
  • 4
    • 2942699911 scopus 로고    scopus 로고
    • Combined corticosteroid and cyclophosphamide therapy does not alter survival in idiopathic pulmonary fibrosis
    • Collard, H.R.; Ryu, J.H.; Douglas, W.W.; Schwarz, M.I.; Curran-Everett, D.; King, T.E., Jr.; Brown, K.K. Combined corticosteroid and cyclophosphamide therapy does not alter survival in idiopathic pulmonary fibrosis. Chest 2004, 125, 2169-2174.
    • (2004) Chest , vol.125 , pp. 2169-2174
    • Collard, H.R.1    Ryu, J.H.2    Douglas, W.W.3    Schwarz, M.I.4    Curran-Everett, D.5    King Jr., T.E.6    Brown, K.K.7
  • 5
    • 79952717349 scopus 로고    scopus 로고
    • ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis. An official ATS/ERS/JRS/ALAT statement: Idiopathic pulmonary fibrosis: Evidence-based guidelines for diagnosis and management
    • Raghu, G.; Collard, H.R.; Egan, J.J.; Martinez, F.J.; Behr, J.; Brown, K.K.; Colby, T.V.; Cordier, J.F.; Flaherty, K.R.; Lasky, J.A. et al. ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis. An official ATS/ERS/JRS/ALAT statement: Idiopathic pulmonary fibrosis: Evidence-based guidelines for diagnosis and management. Am. J. Respir. Crit. Care Med. 2011, 183, 788-824.
    • (2011) Am. J. Respir. Crit. Care Med , vol.183 , pp. 788-824
    • Raghu, G.1    Collard, H.R.2    Egan, J.J.3    Martinez, F.J.4    Behr, J.5    Brown, K.K.6    Colby, T.V.7    Cordier, J.F.8    Flaherty, K.R.9    Lasky, J.A.10
  • 7
    • 84879476665 scopus 로고    scopus 로고
    • Simvastatin attenuates TGF-β1-induced epithelial-mesenchymal transition in human alveolar epithelial cells
    • Yang, T.; Chen, M.; Sun, T. Simvastatin attenuates TGF-β1-induced epithelial-mesenchymal transition in human alveolar epithelial cells. Cell. Physiol. Biochem. 2013, 31, 863-874.
    • (2013) Cell. Physiol. Biochem , vol.31 , pp. 863-874
    • Yang, T.1    Chen, M.2    Sun, T.3
  • 8
    • 84879682510 scopus 로고    scopus 로고
    • Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: Potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation
    • Chen, Y.L.; Zhang, X.; Bai, J.; Gai, L.; Ye, X.L.; Zhang, L.; Xu, Q.; Zhang, Y.X.; Xu, L.; Li, H.P. et al. Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: Potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation. Cell Death Dis. 2013, 4, e665.
    • (2013) Cell Death Dis , vol.4
    • Chen, Y.L.1    Zhang, X.2    Bai, J.3    Gai, L.4    Ye, X.L.5    Zhang, L.6    Xu, Q.7    Zhang, Y.X.8    Xu, L.9    Li, H.P.10
  • 9
    • 84878911507 scopus 로고    scopus 로고
    • Clinical relevance of plasma prostaglandin f2α metabolite concentrations in patients with idiopathic pulmonary fibrosis
    • Aihara, K.; Handa, T.; Oga, T.; Watanabe, K.; Tanizawa, K.; Ikezoe, K.; Taguchi, Y.; Sato, H.; Chin, K.; Nagai, S. et al. Clinical relevance of plasma prostaglandin f2α metabolite concentrations in patients with idiopathic pulmonary fibrosis. PLoS One 2013, 8, e66017.
    • (2013) PLoS One , vol.8
    • Aihara, K.1    Handa, T.2    Oga, T.3    Watanabe, K.4    Tanizawa, K.5    Ikezoe, K.6    Taguchi, Y.7    Sato, H.8    Chin, K.9    Nagai, S.10
  • 10
    • 84878640280 scopus 로고    scopus 로고
    • Lung myofibroblasts are characterized by down-regulated cyclooxygenase-2 and its main metabolite, prostaglandin E2
    • Gabasa, M.; Royo, D.; Molina-Molina, M.; Roca-Ferrer, J.; Pujols, L.; Picado, C.; Xaubet, A.; Pereda, J. Lung myofibroblasts are characterized by down-regulated cyclooxygenase-2 and its main metabolite, prostaglandin E2. PLoS One 2013, 8, e65445.
    • (2013) PLoS One , vol.8
    • Gabasa, M.1    Royo, D.2    Molina-Molina, M.3    Roca-Ferrer, J.4    Pujols, L.5    Picado, C.6    Xaubet, A.7    Pereda, J.8
  • 12
    • 84874881483 scopus 로고    scopus 로고
    • Molecules altering the intracellular thiol content modulate NF-κB and STAT-1/IRF-1 signalling pathways and IL-12 p40 and IL-27 p28 production in murine macrophages
    • Fraternale, A.; Crinelli, R.; Casabianca, A.; Paoletti, M.F.; Orlandi, C.; Carloni, E.; Smietana, M.; Palamara, A.T.; Magnani, M. Molecules altering the intracellular thiol content modulate NF-κB and STAT-1/IRF-1 signalling pathways and IL-12 p40 and IL-27 p28 production in murine macrophages. PLoS One 2013, 8, e57866.
    • (2013) PLoS One , vol.8
    • Fraternale, A.1    Crinelli, R.2    Casabianca, A.3    Paoletti, M.F.4    Orlandi, C.5    Carloni, E.6    Smietana, M.7    Palamara, A.T.8    Magnani, M.9
  • 13
    • 84876300088 scopus 로고    scopus 로고
    • Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: A biphasic experimental study
    • Chitra, P.; Saiprasad, G.; Manikandan, R.; Sudhandiran, G. Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: A biphasic experimental study. Toxicol. Lett. 2013, 219, 178-193.
    • (2013) Toxicol. Lett , vol.219 , pp. 178-193
    • Chitra, P.1    Saiprasad, G.2    Manikandan, R.3    Sudhandiran, G.4
  • 14
    • 84877065428 scopus 로고    scopus 로고
    • Transcriptional regulation of increased CCL2 expression in pulmonary fibrosis involves nuclear factor-κB and activator protein-1
    • Deng, X.; Xu, M.; Yuan, C.; Yin, L.; Chen, X.; Zhou, X.; Li, G.; Fu, Y.; Feghali-Bostwick, C.A.; Pang, L. Transcriptional regulation of increased CCL2 expression in pulmonary fibrosis involves nuclear factor-κB and activator protein-1. Int. J. Biochem. Cell Biol. 2013, 45, 1366-1376.
    • (2013) Int. J. Biochem. Cell Biol , vol.45 , pp. 1366-1376
    • Deng, X.1    Xu, M.2    Yuan, C.3    Yin, L.4    Chen, X.5    Zhou, X.6    Li, G.7    Fu, Y.8    Feghali-Bostwick, C.A.9    Pang, L.10
  • 15
    • 84864371060 scopus 로고    scopus 로고
    • Fasudil, a rho-kinase inhibitor, attenuates bleomycin-induced pulmonary fibrosis in mice
    • Jiang, C.; Huang, H.; Liu, J.; Wang, Y.; Lu, Z.; Xu, Z. Fasudil, a rho-kinase inhibitor, attenuates bleomycin-induced pulmonary fibrosis in mice. Int. J. Mol. Sci. 2012, 13, 8293-8307.
    • (2012) Int. J. Mol. Sci , vol.13 , pp. 8293-8307
    • Jiang, C.1    Huang, H.2    Liu, J.3    Wang, Y.4    Lu, Z.5    Xu, Z.6
  • 16
    • 33748913137 scopus 로고    scopus 로고
    • Insulin-like growth factor-I signaling mechanisms, type I collagen and alpha smooth muscle actin in human fetal lung fibroblasts
    • Chetty, A.; Cao, G.J.; Nielsen, H.C. Insulin-like growth factor-I signaling mechanisms, type I collagen and alpha smooth muscle actin in human fetal lung fibroblasts. Pediatr. Res. 2006, 60, 389-394.
    • (2006) Pediatr. Res , vol.60 , pp. 389-394
    • Chetty, A.1    Cao, G.J.2    Nielsen, H.C.3
  • 19
    • 60249088269 scopus 로고    scopus 로고
    • In vitro and in vivo anti-inflammatory effects of andrographolide
    • Abu-Ghefreh, A.A.; Canatan, H.; Ezeamuzie, C.I. In vitro and in vivo anti-inflammatory effects of andrographolide. Int. Immunopharmacol. 2009, 9, 313-318.
    • (2009) Int. Immunopharmacol , vol.9 , pp. 313-318
    • Abu-Ghefreh, A.A.1    Canatan, H.2    Ezeamuzie, C.I.3
  • 20
    • 65249122527 scopus 로고    scopus 로고
    • A novel antiinflammatory role for andrographolide in asthma via inhibition of the nuclear factor-kappaB pathway
    • Bao, Z.; Guan, S.; Cheng, C.; Wu, S.; Wong, S.H.; Kemeny, D.M.; Leung, B.P.; Wong, W.S. A novel antiinflammatory role for andrographolide in asthma via inhibition of the nuclear factor-kappaB pathway. Am. J. Respir. Crit. Care Med. 2009, 179, 657-665.
    • (2009) Am. J. Respir. Crit. Care Med , vol.179 , pp. 657-665
    • Bao, Z.1    Guan, S.2    Cheng, C.3    Wu, S.4    Wong, S.H.5    Kemeny, D.M.6    Leung, B.P.7    Wong, W.S.8
  • 21
    • 84881129513 scopus 로고    scopus 로고
    • Constitutive and tumor necrosis factor-α-induced activation of nuclear factor-κB in adenomyosis and its inhibition by andrographolide
    • Li, B.; Chen, M.; Liu, X.; Guo, S.W. Constitutive and tumor necrosis factor-α-induced activation of nuclear factor-κB in adenomyosis and its inhibition by andrographolide. Fertil. Steril. 2013, 100, 568-577.
    • (2013) Fertil. Steril , vol.100 , pp. 568-577
    • Li, B.1    Chen, M.2    Liu, X.3    Guo, S.W.4
  • 22
    • 67849121334 scopus 로고    scopus 로고
    • Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: A prospective randomized placebo-controlled trial
    • Burgos, R.A.; Hancke, J.L.; Bertoglio, J.C.; Aguirre, V.; Arriagada, S.; Calvo, M.; Cáceres, D.D. Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: A prospective randomized placebo-controlled trial. Clin. Rheumatol. 2009, 28, 931-946.
    • (2009) Clin. Rheumatol , vol.28 , pp. 931-946
    • Burgos, R.A.1    Hancke, J.L.2    Bertoglio, J.C.3    Aguirre, V.4    Arriagada, S.5    Calvo, M.6    Cáceres, D.D.7
  • 25
    • 80052456289 scopus 로고    scopus 로고
    • Phosphodiesterase-4 inhibition combined with isoniazid treatment of rabbits with pulmonary tuberculosis reduces macrophage activation and lung pathology
    • Subbian, S.; Tsenova, L.; O'Brien, P.; Yang, G.; Koo, M.S.; Peixoto, B.; Fallows, D.; Zeldis, J.B.; Muller, G.; Kaplan, G. Phosphodiesterase-4 inhibition combined with isoniazid treatment of rabbits with pulmonary tuberculosis reduces macrophage activation and lung pathology. Am. J. Pathol. 2011, 179, 289-301.
    • (2011) Am. J. Pathol , vol.179 , pp. 289-301
    • Subbian, S.1    Tsenova, L.2    O'Brien, P.3    Yang, G.4    Koo, M.S.5    Peixoto, B.6    Fallows, D.7    Zeldis, J.B.8    Muller, G.9    Kaplan, G.10
  • 26
    • 84880584677 scopus 로고    scopus 로고
    • Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS
    • Zhu, T.; Guan, X.; Zhang, W.; Wang, D. Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS. Nan Fang Yi Ke Da Xue Xue Bao 2012, 32, 1238-1241.
    • (2012) Nan Fang Yi Ke Da Xue Xue Bao , vol.32 , pp. 1238-1241
    • Zhu, T.1    Guan, X.2    Zhang, W.3    Wang, D.4
  • 28
    • 84877854763 scopus 로고    scopus 로고
    • Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats
    • Wan, Y.Y.; Tian, G.Y.; Guo, H.S.; Kang, Y.M.; Yao, Z.H.; Li, X.L.; Liu, Q.H.; Lin, D.J. Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats. Respir. Res. 2013, 14, 56.
    • (2013) Respir. Res , vol.14 , pp. 56
    • Wan, Y.Y.1    Tian, G.Y.2    Guo, H.S.3    Kang, Y.M.4    Yao, Z.H.5    Li, X.L.6    Liu, Q.H.7    Lin, D.J.8
  • 30
    • 77649253590 scopus 로고    scopus 로고
    • N-acetylcysteine inhibits TNF-alpha, sTNFR, and TGF-beta1 release by alveolar macrophages in idiopathic pulmonary fibrosis in vitro. Sarcoidosis Vasc. Diffus
    • Cu, A.; Ye, Q.; Sarria, R.; Nakamura, S.; Guzman, J.; Costabel, U. N-acetylcysteine inhibits TNF-alpha, sTNFR, and TGF-beta1 release by alveolar macrophages in idiopathic pulmonary fibrosis in vitro. Sarcoidosis Vasc. Diffus. Lung Dis. 2009, 26, 147-154.
    • (2009) Lung Dis , vol.26 , pp. 147-154
    • Cu, A.1    Ye, Q.2    Sarria, R.3    Nakamura, S.4    Guzman, J.5    Costabel, U.6
  • 32
    • 17844384822 scopus 로고    scopus 로고
    • Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis
    • Willis, B.C.; Liebler, J.M.; Luby-Phelps, K.; Nicholson, A.G.; Crandall, E.D.; du Bois, R.M.; Borok, Z. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis. Am. J. Pathol. 2005, 166, 1321-1332.
    • (2005) Am. J. Pathol , vol.166 , pp. 1321-1332
    • Willis, B.C.1    Liebler, J.M.2    Luby-Phelps, K.3    Nicholson, A.G.4    Crandall, E.D.5    du Bois, R.M.6    Borok, Z.7
  • 35
    • 84860445793 scopus 로고    scopus 로고
    • Rosuvastatin attenuates mucus secretion in a murine model of chronic asthma by inhibiting the gamma-aminobutyric acid type A receptor
    • Zhu, T.; Zhang, W.; Wang, D.X.; Huang, N.W.; Bo, H.; Deng, W.; Deng, J. Rosuvastatin attenuates mucus secretion in a murine model of chronic asthma by inhibiting the gamma-aminobutyric acid type A receptor. Chin. Med. J. (Engl.) 2012, 125, 1457-1464.
    • (2012) Chin. Med. J. (Engl.) , vol.125 , pp. 1457-1464
    • Zhu, T.1    Zhang, W.2    Wang, D.X.3    Huang, N.W.4    Bo, H.5    Deng, W.6    Deng, J.7
  • 36
    • 84878616413 scopus 로고    scopus 로고
    • Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma
    • Xiao, M.; Zhu, T.; Wang, T.; Wen, F.Q. Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma. Eur. Rev. Med. Pharmacol. Sci. 2013, 17, 1033-1043.
    • (2013) Eur. Rev. Med. Pharmacol. Sci , vol.17 , pp. 1033-1043
    • Xiao, M.1    Zhu, T.2    Wang, T.3    Wen, F.Q.4
  • 37
    • 84863515652 scopus 로고    scopus 로고
    • Insulin up-regulates epithelial sodium channel in LPS-induced acute lung injury model in rats by SGK1 activation
    • Zhu, T.; Zhang, W.; Wang, D.X. Insulin up-regulates epithelial sodium channel in LPS-induced acute lung injury model in rats by SGK1 activation. Injury 2012, 43, 1277-1283.
    • (2012) Injury , vol.43 , pp. 1277-1283
    • Zhu, T.1    Zhang, W.2    Wang, D.X.3
  • 38
    • 80053651921 scopus 로고    scopus 로고
    • Black tea extract prevents lipopolysaccharide-induced NF-κB signaling and attenuates dextran sulfate sodium-induced experimental colitis
    • Song, Y.A.; Park, Y.L.; Kim, K.Y.; Chung, C.Y.; Lee, G.H.; Cho, D.H.; Ki, H.S.; Park, K.J.; Cho, S.B.; Lee, W.S.; et al. Black tea extract prevents lipopolysaccharide-induced NF-κB signaling and attenuates dextran sulfate sodium-induced experimental colitis. BMC Complement. Altern. Med. 2011, 11, 91.
    • (2011) BMC Complement. Altern. Med , vol.11 , pp. 91
    • Song, Y.A.1    Park, Y.L.2    Kim, K.Y.3    Chung, C.Y.4    Lee, G.H.5    Cho, D.H.6    Ki, H.S.7    Park, K.J.8    Cho, S.B.9    Lee, W.S.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.