An 8-O-4′ norlignan exerts oestrogen-like actions in osteoblastic cells via rapid nongenomic ER signaling pathway

Journal of Ethnopharmacology

Volumn 170, Issue , 2015, Pages 39-49

  Xiao, Hui Hui ^a   Gao, Quan Gui ^a   Ho, Ming Xian ^a   Zhang, Yan ^a,b   Wong, Ka Chun ^a   Dai, Yi ^c   Yao, Xin Sheng ^c   Wong, Man Sau ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY   (China)

^c JINAN UNIVERSITY   (China)

Author keywords

8 O 4 lignan; MAP kinase signaling pathway; Osteoblast; Phytoestrogen; Sambucus willamsii Hance

Indexed keywords

1 (4 HYDROXY 3 METHOXYPHENYL) 2 [4 (3 HYDROXYPROPYL) 2 METHOXYPHENOXY] 1,3 PROPANEDIOL; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ALKALINE PHOSPHATASE; CALCIUM; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PHYTOESTROGEN; SERINE; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; (7R,8S)-1-(4-HYDROXY-3-METHOXYPHENYL)-2-(4-(3-HYDROXYPROPYL)-2-METHOXYPHENOXY)-1,3-PROPANEDIOL; LIGNAN;

ANIMAL CELL; ARTICLE; BINDING ASSAY; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; ESTROGEN ACTIVITY; GENE EXPRESSION; IMMUNOBLOTTING; LUCIFERASE ASSAY; MESENCHYME CELL; MOUSE; NONHUMAN; OSTEOBLAST; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BONE; CELL LINE; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; PHOSPHORYLATION; SAMBUCUS;

CAPRIFOLIACEAE; MUS; RATTUS; SAMBUCUS; SAMBUCUS WILLIAMSII;

ANIMALS; BONE AND BONES; CELL LINE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; LIGNANS; MAP KINASE SIGNALING SYSTEM; MICE; OSTEOBLASTS; PHOSPHORYLATION; PHYTOESTROGENS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SAMBUCUS; SIGNAL TRANSDUCTION;

EID: 84930648193     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.05.012     Document Type: Article

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