Mitogen-activated protein kinase (MAPK) pathway mediates the oestrogen-like activities of ginsenoside Rg1 in human breast cancer (MCF-7) cells

British Journal of Pharmacology

Volumn 156, Issue 7, 2009, Pages 1136-1146

  Lau, Wai Sum ^a,b   Chen, Wen Fang ^a,c   Chan, Robbie Yat Kan ^a,b   Guo, De An ^d   Wong, Man Sau ^a,b  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b State Key Laboratory of Chinese Medicine and Molecular Pharmacology   (China)

^c QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^d SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

ER ; Ginsenoside Rg1; MAPK; Phytoestrogens

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; GENISTEIN; GINSENG EXTRACT; GINSENOSIDE RG 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN PS2; SOMATOMEDIN BINDING PROTEIN; FLAVONOID; GINSENOSIDE; PROTEIN TYROSINE KINASE; SOMATOMEDIN C RECEPTOR;

ARTICLE; BREAST CANCER; CELL PROLIFERATION; CELL STRAIN HEK293; CELL STRAIN MCF 7; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG INHIBITION; ESTROGEN ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; BIOSYNTHESIS; BREAST TUMOR; CELL LINE; DRUG ANTAGONISM; DRUG POTENTIATION; ENZYME ACTIVATION; FEMALE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL LINE;

BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME ACTIVATION; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; FLAVONOIDS; GENISTEIN; GINSENOSIDES; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RECEPTOR, IGF TYPE 1;

EID: 67650113346     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00123.x     Document Type: Article

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