Reciprocal regulation of c-Maf tyrosine phosphorylation by Tec and Ptpn22

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Liu, Chih Chun ^a   Lai, Chen Yen ^a   Yen, Wei Feng ^a   Lin, Yu Hsien ^a   Chang, Hui Hsin ^b   Tai, Tzong Shyuan ^b   Lu, Yu Jung ^a   Tsao, Hsiao Wei ^a   Ho, I Cheng ^b   Miaw, Shi Chuen ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 21; INTERLEUKIN 4; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR C MAF; TYROSINE; TYROSINE KINASE TEC; UNCLASSIFIED DRUG; INTERLEUKIN DERIVATIVE; PHOSPHOTYROSINE; PROTEIN BINDING; PTPN22 PROTEIN, MOUSE; TEC PROTEIN-TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TH17 CELL; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL NUCLEUS; GENETICS; HEK293 CELL LINE; KNOCKOUT MOUSE; METABOLISM; PHOSPHORYLATION; TWO HYBRID SYSTEM;

ANIMALS; CELL NUCLEUS; HEK293 CELLS; HUMANS; INTERLEUKIN-4; INTERLEUKINS; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; PHOSPHOTYROSINE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-MAF; TH17 CELLS; TRANSCRIPTIONAL ACTIVATION; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 84930642701     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0127617     Document Type: Article

References (32)

1. Ho IC, Hodge MR, Rooney JW, Glimcher LH. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell. 1996; 85(7):973-83. PMID: 8674125.
2. Ho IC, Lo D, Glimcher LH. c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and-independent mechanisms. J Exp Med. 1998; 188(10):1859-66. PMID: 9815263; PubMed Central PMCID: PMC2212398.
3. Bauquet AT, Jin H, Paterson AM, Mitsdoerffer M, Ho IC, Sharpe AH, et al. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat Immunol. 2009; 10(2):167-75. doi: 10.1038/ni.1690 PMID: 19098919; PubMed Central PMCID: PMC2742982.
4. Pot C, Jin H, Awasthi A, Liu SM, Lai CY, Madan R, et al. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. JImmunol. 2009; 183(2):797-801. doi: 10.4049/jimmunol.0901233 PMID: 19570826
5. Kim JI, Ho IC, Grusby MJ, Glimcher LH. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity. 1999; 10(6):745-51. PMID: 10403649.
6. Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami S, Suzuki K, et al. Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORgammat induction as downstream targets of Stat3. J Exp Med. 2014; 211(9):1857-74. doi: 10.1084/jem.20130791 PMID: 25073789; PubMed Central PMCID: PMC4144730.
7. Rutz S, Noubade R, Eidenschenk C, Ota N, Zeng W, Zheng Y, et al. Transcription factor c-Maf mediates the TGF-beta-dependent suppression of IL-22 production in T(H)17 cells. Nat Immunol. 2011; 12(12):1238-45. doi: 10.1038/ni.2134 PMID: 22001828.
8. Apetoh L, Quintana FJ, Pot C, Joller N, Xiao S, Kumar D, et al. The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27. NatImmunol. 2010; 11(9):854-61.
9. Xu J, Yang Y, Qiu G, Lal G, Wu Z, Levy DE, et al. c-Maf regulates IL-10 expression during Th17 polarization. J Immunol. 2009; 182(10):6226-36. doi: 10.4049/jimmunol.0900123 PMID: 19414776; PubMed Central PMCID: PMC2834209.
10. Lai CY, Lin SY, Wu CK, Yeh LT, Sytwu HK, Miaw SC. Tyrosine phosphorylation of c-Maf enhances the expression of IL-4 gene. J Immunol. 2012; 189(4):1545-50. Epub 2012/07/17. doi: jimmunol.1200405 [pii] doi: 10.4049/jimmunol.1200405 PMID: 22798672.
11. Hu Q, Davidson D, Schwartzberg PL, Macchiarini F, Lenardo MJ, Bluestone JA, et al. Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage. J Biol Chem. 1995; 270(4):1928-34. PMID: 7829530.
12. Tomlinson MG, Kane LP, Su J, Kadlecek TA, Mollenauer MN, Weiss A. Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec. Mol Cell Biol. 2004; 24(6):2455-66. PMID: 14993283; PubMed Central PMCID: PMC355844.
13. Miller AT, Wilcox HM, Lai Z, Berg LJ. Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet. Immunity. 2004; 21(1):67-80. doi: 10.1016/j.immuni.2004.06.009 PMID: 15345221.
14. Boucheron N, Ellmeier W. The role of Tec family kinases in the regulation of T-helper-cell differentiation. Int Rev Immunol. 2012; 31(2):133-54. doi: 10.3109/08830185.2012.664798 PMID: 22449074.
15. Schaeffer EM, Debnath J, Yap G, McVicar D, Liao XC, Littman DR, et al. Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science. 1999; 284(5414):638-41. PMID: 10213685.
16. Schaeffer EM, Yap GS, Lewis CM, Czar MJ, McVicar DW, Cheever AW, et al. Mutation of Tec family kinases alters T helper cell differentiation. Nat Immunol. 2001; 2(12):1183-8. doi: 10.1038/ni734 PMID: 11702066.
17. Boucheron N, Sharif O, Schebesta A, Croxford A, Raberger J, Schmidt U, et al. The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. J Immunol. 2010; 185(9):5111-9. doi: 10.4049/jimmunol.1001734 PMID: 20870948.
18. Hwang ES, Szabo SJ, Schwartzberg PL, Glimcher LH. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science. 2005; 307(5708):430-3. doi: 10.1126/science.1103336 PMID: 15662016.
19. Matthews RJ, Bowne DB, Flores E, Thomas ML. Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences. MolCell Biol. 1992; 12(5):2396-405. PMID: 1373816
20. Gjorloff-Wingren A, Saxena M, Williams S, Hammi D, Mustelin T. Characterization of TCR-induced receptor-proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP. Eur J Immunol. 1999; 29(12):3845-54. doi: 10.1002/(SICI)1521-4141(199912)29:12<3845::AID-IMMU3845>3.0.CO;2-U PMID: 10601992.
21. Ghose R, Shekhtman A, Goger MJ, Ji H, Cowburn D. A novel, specific interaction involving the Csk SH3 domain and its natural ligand. Nature structural biology. 2001; 8(11):998-1004. doi: 10.1038/nsb1101-998 PMID: 11685249.
22. Wu J, Katrekar A, Honigberg LA, Smith AM, Conn MT, Tang J, et al. Identification of substrates of human protein-tyrosine phosphatase PTPN22. J Biol Chem. 2006; 281(16):11002-10. doi: 10.1074/jbc.M600498200 PMID: 16461343.
23. Hasegawa K, Martin F, Huang G, Tumas D, Diehl L, Chan AC. PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells. Science. 2004; 303(5658):685-9. PMID: 14752163
24. Begovich AB, Carlton VE, Honigberg LA, Schrodi SJ, Chokkalingam AP, Alexander HC, et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. AmJHumGenet. 2004; 75(2):330-7. PMID: 15208781
25. Chung SA, Criswell LA. PTPN22: its role in SLE and autoimmunity. Autoimmunity. 2007; 40(8):582-90. doi: 10.1080/08916930701510848 PMID: 18075792; PubMed Central PMCID: PMC2875134.
26. Chang HH, Tai TS, Lu B, Iannaccone C, Cernadas M, Weinblatt M, et al. PTPN22.6, a dominant negative isoform of PTPN22 and potential biomarker of rheumatoid arthritis. PloS one. 2012; 7(3):e33067. doi: 10.1371/journal.pone.0033067 PMID: 22427951; PubMed Central PMCID: PMC3299735.
27. Chang HH, Miaw SC, Tseng W, Sun YW, Liu CC, Tsao HW, et al. PTPN22 modulates macrophage polarization and susceptibility to dextran sulfate sodium-induced colitis. J Immunol. 2013; 191(5):2134-43. doi: 10.4049/jimmunol.1203363 PMID: 23913970.
28. Lin BS, Tsai PY, Hsieh WY, Tsao HW, Liu MW, Grenningloh R, et al. SUMOylation attenuates c-Maf-dependent IL-4 expression. Eur J Immunol. 2010; 40(4):1174-84. Epub 2010/02/04. doi: 10.1002/eji.200939788 PMID: 20127678.
29. Yang WC, Ghiotto M, Barbarat B, Olive D. The role of Tec protein-tyrosine kinase in T cell signaling. J Biol Chem. 1999; 274(2):607-17. PMID: 9872994.
30. Yang WC, Ching KA, Tsoukas CD, Berg LJ. Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain. J Immunol. 2001; 166(1):387-95. PMID: 11123316.
31. Barr AJ, Ugochukwu E, Lee WH, King ON, Filippakopoulos P, Alfano I, et al. Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell. 2009; 136(2):352-63. doi: 10.1016/j.cell.2008.11.038 PMID: 19167335; PubMed Central PMCID: PMC2638020.
32. Davidson D, Shi X, Zhong MC, Rhee I, Veillette A. The phosphatase PTP-PEST promotes secondary T cell responses by dephosphorylating the protein tyrosine kinase Pyk2. Immunity. 2010; 33(2):167-80. doi: 10.1016/j.immuni.2010.08.001 PMID: 20727793.