Tyrosine phosphorylation of c-Maf enhances the expression of IL-4 gene

Journal of Immunology

Volumn 189, Issue 4, 2012, Pages 1545-1550

  Lai, Chen Yen ^a   Lin, Shin Ying ^a   Wu, Chia Kai ^a   Yeh, Li Tzu ^b   Sytwu, Huey Kang ^b   Miaw, Shi Chuen ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4; TRANSCRIPTION FACTOR C MAF; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; GENE; GENE EXPRESSION; GENE INTERACTION; HUMAN; HUMAN CELL; IL 4 GENE; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RAT; TH2 CELL;

EID: 84864823874     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200405     Document Type: Article

References (17)

1. Kataoka, K., M. Nishizawa, and S. Kawai. 1993. Structure-function analysis of the maf oncogene product, a member of the b-Zip protein family. J. Virol. 67:2133-2141. (Pubitemid 23088388)
2. Bauquet, A. T., H. Jin, A. M. Paterson, M. Mitsdoerffer, I. C. Ho, A. H. Sharpe, and V. K. Kuchroo. 2009. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat. Immunol. 10: 167-175.
3. Apetoh, L., F. J. Quintana, C. Pot, N. Joller, S. Xiao, D. Kumar, E. J. Burns, D. H. Sherr, H. L. Weiner, and V. K. Kuchroo. 2010. The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27. Nat. Immunol. 11: 854-861.
4. Leavenworth, J. W., X. Ma, Y. Y. Mo, and M. E. Pauza. 2009. SUMO conjugation contributes to immune deviation in nonobese diabetic mice by suppressing c-Maf transactivation of IL-4. J. Immunol. 183: 1110-1119.
5. Lin, B. S., P. Y. Tsai, W. Y. Hsieh, H. W. Tsao, M. W. Liu, R. Grenningloh, L. F. Wang, I. C. Ho, and S. C. Miaw. 2010. SUMOylation attenuates c-Maf-dependent IL-4 expression. Eur. J. Immunol. 40: 1174-1184.
6. Rocques, N., N. Abou Zeid, K. Sii-Felice, L. Lecoin, M. P. Felder-Schmittbuhl, A. Eychène, and C. Pouponnot. 2007. GSK-3-mediated phosphorylation enhances Maf-transforming activity. Mol. Cell 28: 584-597. (Pubitemid 350137803)
7. Zheng, L., U. Baumann, and J. L. Reymond. 2004. An efficient one-step site-directed and site-saturation mutagenesis protocol. Nucleic Acids Res. 32: e115.
8. Hwang, E. S., S. J. Szabo, P. L. Schwartzberg, and L. H. Glimcher. 2005. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science 307: 430-433. (Pubitemid 40139989)
9. Chen, A., S. M. Lee, B. Gao, S. Shannon, Z. Zhu, and D. Fang. 2011. c-Abl-mediated tyrosine phosphorylation of the T-bet DNA-binding domain regulates CD4+ T-cell differentiation and allergic lung inflammation. Mol. Cell. Biol. 31:3445-3456.
10. Chen, C. H., D. H. Zhang, J. M. LaPorte, and A. Ray. 2000. Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression. J. Immunol. 165:5597-5605.
11. Grenningloh, R., S. C. Miaw, J. Moisan, B. J. Graves, and I. C. Ho. 2008. Role of Ets-1 phosphorylation in the effector function of Th cells. Eur. J. Immunol. 38:1700-1705.
12. Anderson, M. S., and J. A. Bluestone. 2005. The NOD mouse: a model of immune dysregulation. Annu. Rev. Immunol. 23: 447-485. (Pubitemid 40563177)
13. Whitmarsh, A. J., and R. J. Davis. 2000. Regulation of transcription factor function by phosphorylation. Cell. Mol. Life Sci. 57: 1172-1183. (Pubitemid 30663475)
14. Hietakangas, V., J. Anckar, H. A. Blomster, M. Fujimoto, J. J. Palvimo, A. Nakai, and L. Sistonen. 2006. PDSM, a motif for phosphorylation-dependent SUMO modification. Proc. Natl. Acad. Sci. USA 103: 45-50. (Pubitemid 43076102)
15. Song, L., S. Bhattacharya, A. A. Yunus, C. D. Lima, and C. Schindler. 2006. Stat1 and SUMO modification. Blood 108: 3237-3244.
16. Elias, D., A. Meilin, V. Ablamunits, O. S. Birk, P. Carmi, S. Könen-Waisman, and I. R. Cohen. 1997. Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various beta-cell antigens. Diabetes 46: 758-764. (Pubitemid 27188251)
17. Tisch, R., B. Wang, and D. V. Serreze. 1999. Induction of glutamic acid decarboxylase 65-specific Th2 cells and suppression of autoimmune diabetes at late stages of disease is epitope dependent. J. Immunol. 163: 1178-1187. (Pubitemid 29352732)