Oxidatively generated guanine(C8)-Thymine(N3) intrastrand cross-links in double-stranded DNA are repaired by base excision repair pathways

Journal of Biological Chemistry

Volumn 290, Issue 23, 2015, Pages 14610-14617

  Talhaoui, Ibtissam ^a   Shafirovich, Vladimir ^e   Liu, Zhi ^e   Saint Pierre, Christine ^b   Akishev, Zhiger ^c   Matkarimov, Bakhyt T ^d   Gasparutto, Didier ^b   Geacintov, Nicholas E ^e   Saparbaev, Murat ^a  

^a Gustave Roussy Comprehensive Cancer Institute   (France)

^b UNIV GRENOBLE ALPES   (France)

^c AL FARABI KAZAKH NATIONAL UNIVERSITY   (Kazakhstan)

^d NAZARBAYEV UNIVERSITY   (Kazakhstan)

^e NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MOBILE SECURITY; NUCLEIC ACIDS; POSITIVE IONS;

BASE EXCISION REPAIRS; CLEAVAGE PRODUCTS; DEFENSE MECHANISM; DOUBLE STRANDED DNA; GUANINE RADICALS; HUMAN CELL EXTRACTS; NUCLEOPHILIC REACTION; NUCLEOTIDE EXCISION REPAIR;

DNA;

DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA FRAGMENT; DNA GLYCOSYLTRANSFERASE; DOUBLE STRANDED DNA; GUANINE; NUCLEOTIDE; OXYGEN; THYMINE; DNA; OLIGONUCLEOTIDE;

ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; DNA CROSS LINKING; EXCISION REPAIR; GENOTOXICITY; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; NUCLEOPHILICITY; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; CHEMISTRY; DNA REPAIR; HELA CELL LINE; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION;

EUKARYOTA; PROKARYOTA;

BASE SEQUENCE; DNA; DNA GLYCOSYLASES; DNA REPAIR; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; OXIDATION-REDUCTION;

EID: 84930634082     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.647487     Document Type: Article

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