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Volumn 6, Issue 3, 2011, Pages

Location of intra- and extracellular M. tuberculosis populations in lungs of mice and guinea pigs during disease progression and after drug treatment

Author keywords

[No Author keywords available]

Indexed keywords

ISONIAZID; MOXIFLOXACIN; RIFAMPICIN; TUBERCULOSTATIC AGENT;

EID: 79952847428     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017550     Document Type: Article
Times cited : (98)

References (86)
  • 1
    • 0037945849 scopus 로고    scopus 로고
    • WHO annual report on global TB control-summary
    • (2003) WHO annual report on global TB control-summary. Wkly Epidemiol Rec 78: 122-128.
    • (2003) Wkly Epidemiol Rec , vol.78 , pp. 122-128
  • 2
    • 40949103486 scopus 로고    scopus 로고
    • Trends in tuberculosis-United States, 2007
    • (2008) Trends in tuberculosis-United States, 2007. MMWR Morb Mortal Wkly Rep 57: 281-285.
    • (2008) MMWR Morb Mortal Wkly Rep , vol.57 , pp. 281-285
  • 3
    • 0347091999 scopus 로고    scopus 로고
    • M. tuberculosis persistence, latency, and drug tolerance
    • Gomez JE, McKinney JD, (2004) M. tuberculosis persistence, latency, and drug tolerance. Tuberculosis (Edinb) 84: 29-44.
    • (2004) Tuberculosis (Edinb) , vol.84 , pp. 29-44
    • Gomez, J.E.1    McKinney, J.D.2
  • 4
    • 37349033017 scopus 로고    scopus 로고
    • Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis
    • Sacchettini JC, Rubin EJ, Freundlich JS, (2008) Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis. Nat Rev Microbiol 6: 41-52.
    • (2008) Nat Rev Microbiol , vol.6 , pp. 41-52
    • Sacchettini, J.C.1    Rubin, E.J.2    Freundlich, J.S.3
  • 5
    • 67349255827 scopus 로고    scopus 로고
    • Lazy, dynamic or minimally recrudescent? On the elusive nature and location of the mycobacterium responsible for latent tuberculosis
    • Ehlers S, (2009) Lazy, dynamic or minimally recrudescent? On the elusive nature and location of the mycobacterium responsible for latent tuberculosis. Infection 37: 87-95.
    • (2009) Infection , vol.37 , pp. 87-95
    • Ehlers, S.1
  • 6
    • 33646143975 scopus 로고    scopus 로고
    • Lessons from experimental Mycobacterium tuberculosis infections
    • Flynn JL, (2006) Lessons from experimental Mycobacterium tuberculosis infections. Microbes Infect 8: 1179-1188.
    • (2006) Microbes Infect , vol.8 , pp. 1179-1188
    • Flynn, J.L.1
  • 7
    • 0028024035 scopus 로고
    • Metronidazole is bactericidal to dormant cells of Mycobacterium tuberculosis
    • Wayne LG, Sramek HA, (1994) Metronidazole is bactericidal to dormant cells of Mycobacterium tuberculosis. Antimicrob Agents Chemother 38: 2054-2058.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 2054-2058
    • Wayne, L.G.1    Sramek, H.A.2
  • 8
    • 3042790827 scopus 로고    scopus 로고
    • Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: a model for persistent organisms?
    • Hampshire T, Soneji S, Bacon J, James BW, Hinds J, et al. (2004) Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: a model for persistent organisms? Tuberculosis (Edinb) 84: 228-238.
    • (2004) Tuberculosis (Edinb) , vol.84 , pp. 228-238
    • Hampshire, T.1    Soneji, S.2    Bacon, J.3    James, B.W.4    Hinds, J.5
  • 9
    • 0034513828 scopus 로고    scopus 로고
    • Rekindling old controversy on elusive lair of latent tuberculosis
    • Bishai WR, (2000) Rekindling old controversy on elusive lair of latent tuberculosis. Lancet 356: 2113-2114.
    • (2000) Lancet , vol.356 , pp. 2113-2114
    • Bishai, W.R.1
  • 10
    • 0031939281 scopus 로고    scopus 로고
    • Mechanisms of latency in Mycobacterium tuberculosis
    • Parrish NM, Dick JD, Bishai WR, (1998) Mechanisms of latency in Mycobacterium tuberculosis. Trends Microbiol 6: 107-112.
    • (1998) Trends Microbiol , vol.6 , pp. 107-112
    • Parrish, N.M.1    Dick, J.D.2    Bishai, W.R.3
  • 11
    • 11144339323 scopus 로고    scopus 로고
    • Replication dynamics of Mycobacterium tuberculosis in chronically infected mice
    • Munoz-Elias EJ, Timm J, Botha T, Chan WT, Gomez JE, et al. (2005) Replication dynamics of Mycobacterium tuberculosis in chronically infected mice. Infect Immun 73: 546-551.
    • (2005) Infect Immun , vol.73 , pp. 546-551
    • Munoz-Elias, E.J.1    Timm, J.2    Botha, T.3    Chan, W.T.4    Gomez, J.E.5
  • 12
    • 77956213734 scopus 로고    scopus 로고
    • Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach
    • [Electronic Resource]
    • Ryan GJ, Hoff DR, Driver ER, Voskuil MI, Gonzalez-Juarrero M, et al. (2010) Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach. PLoS ONE [Electronic Resource] 5: e11108.
    • (2010) PLoS ONE , vol.5
    • Ryan, G.J.1    Hoff, D.R.2    Driver, E.R.3    Voskuil, M.I.4    Gonzalez-Juarrero, M.5
  • 14
    • 0029829728 scopus 로고    scopus 로고
    • Low-dose aerosol infection model for testing drugs for efficacy against Mycobacterium tuberculosis
    • Kelly BP, Furney SK, Jessen MT, Orme IM, (1996) Low-dose aerosol infection model for testing drugs for efficacy against Mycobacterium tuberculosis. Antimicrob Agents Chemother 40: 2809-2812.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 2809-2812
    • Kelly, B.P.1    Furney, S.K.2    Jessen, M.T.3    Orme, I.M.4
  • 15
    • 39049161926 scopus 로고    scopus 로고
    • Preclinical testing of new drugs for tuberculosis: current challenges
    • Lenaerts AJ, Degroote MA, Orme IM, (2008) Preclinical testing of new drugs for tuberculosis: current challenges. Trends Microbiol 16: 48-54.
    • (2008) Trends Microbiol , vol.16 , pp. 48-54
    • Lenaerts, A.J.1    Degroote, M.A.2    Orme, I.M.3
  • 17
    • 53549104456 scopus 로고    scopus 로고
    • Using animal models to develop new treatments for tuberculosis
    • Nuermberger EL, (2008) Using animal models to develop new treatments for tuberculosis. Semin Respir Crit Care Med 29: 542-551.
    • (2008) Semin Respir Crit Care Med , vol.29 , pp. 542-551
    • Nuermberger, E.L.1
  • 18
    • 0031442875 scopus 로고    scopus 로고
    • Progression of chronic pulmonary tuberculosis in mice aerogenically infected with virulent Mycobacterium tuberculosis
    • Rhoades ER, Frank AA, Orme IM, (1997) Progression of chronic pulmonary tuberculosis in mice aerogenically infected with virulent Mycobacterium tuberculosis. Tuber Lung Dis 78: 57-66.
    • (1997) Tuber Lung Dis , vol.78 , pp. 57-66
    • Rhoades, E.R.1    Frank, A.A.2    Orme, I.M.3
  • 19
    • 33750503812 scopus 로고    scopus 로고
    • Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice
    • Aly S, Wagner K, Keller C, Malm S, Malzan A, et al. (2006) Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice. J Pathol 210: 298-305.
    • (2006) J Pathol , vol.210 , pp. 298-305
    • Aly, S.1    Wagner, K.2    Keller, C.3    Malm, S.4    Malzan, A.5
  • 20
    • 33644832153 scopus 로고    scopus 로고
    • Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension
    • Tsai MC, Chakravarty S, Zhu G, Xu J, Tanaka K, et al. (2006) Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension. Cell Microbiol 8: 218-232.
    • (2006) Cell Microbiol , vol.8 , pp. 218-232
    • Tsai, M.C.1    Chakravarty, S.2    Zhu, G.3    Xu, J.4    Tanaka, K.5
  • 21
    • 46249108568 scopus 로고    scopus 로고
    • Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates
    • Via LE, Lin PL, Ray SM, Carrillo J, Allen SS, et al. (2008) Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates. Infect Immun 76: 2333-2340.
    • (2008) Infect Immun , vol.76 , pp. 2333-2340
    • Via, L.E.1    Lin, P.L.2    Ray, S.M.3    Carrillo, J.4    Allen, S.S.5
  • 22
    • 0037304668 scopus 로고    scopus 로고
    • Immunopathogenesis of pulmonary granulomas in the guinea pig after infection with Mycobacterium tuberculosis
    • Turner OC, Basaraba RJ, Orme IM, (2003) Immunopathogenesis of pulmonary granulomas in the guinea pig after infection with Mycobacterium tuberculosis. Infect Immun 71: 864-871.
    • (2003) Infect Immun , vol.71 , pp. 864-871
    • Turner, O.C.1    Basaraba, R.J.2    Orme, I.M.3
  • 23
    • 35948964746 scopus 로고    scopus 로고
    • Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910
    • Lenaerts AJ, Hoff D, Aly S, Ehlers S, Andries K, et al. (2007) Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910. Antimicrob Agents Chemother 51: 3338-3345.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3338-3345
    • Lenaerts, A.J.1    Hoff, D.2    Aly, S.3    Ehlers, S.4    Andries, K.5
  • 24
    • 34848861955 scopus 로고    scopus 로고
    • The cellular immune response to Mycobacterium tuberculosis infection in the guinea pig
    • Ordway D, Palanisamy G, Henao-Tamayo M, Smith EE, Shanley C, et al. (2007) The cellular immune response to Mycobacterium tuberculosis infection in the guinea pig. J Immunol 179: 2532-2541.
    • (2007) J Immunol , vol.179 , pp. 2532-2541
    • Ordway, D.1    Palanisamy, G.2    Henao-Tamayo, M.3    Smith, E.E.4    Shanley, C.5
  • 25
    • 37249059830 scopus 로고    scopus 로고
    • Increased expression of host iron-binding proteins precedes iron accumulation and calcification of primary lung lesions in experimental tuberculosis in the guinea pig
    • Basaraba RJ, Bielefeldt-Ohmann H, Eschelbach EK, Reisenhauer C, Tolnay AE, et al. (2008) Increased expression of host iron-binding proteins precedes iron accumulation and calcification of primary lung lesions in experimental tuberculosis in the guinea pig. Tuberculosis (Edinb) 88: 69-79.
    • (2008) Tuberculosis (Edinb) , vol.88 , pp. 69-79
    • Basaraba, R.J.1    Bielefeldt-Ohmann, H.2    Eschelbach, E.K.3    Reisenhauer, C.4    Tolnay, A.E.5
  • 26
    • 50349094162 scopus 로고    scopus 로고
    • Experimental tuberculosis: the role of comparative pathology in the discovery of improved tuberculosis treatment strategies
    • Basaraba RJ, (2008) Experimental tuberculosis: the role of comparative pathology in the discovery of improved tuberculosis treatment strategies. Tuberculosis (Edinb) 88 (Suppl 1): S35-47.
    • (2008) Tuberculosis (Edinb) , vol.88 , Issue.SUPPL. 1
    • Basaraba, R.J.1
  • 27
    • 70349427123 scopus 로고    scopus 로고
    • Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model
    • Lin PL, Rodgers M, Smith L, Bigbee M, Myers A, et al. (2009) Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model. Infection & Immunity 77: 4631-4642.
    • (2009) Infection & Immunity , vol.77 , pp. 4631-4642
    • Lin, P.L.1    Rodgers, M.2    Smith, L.3    Bigbee, M.4    Myers, A.5
  • 29
    • 0032856514 scopus 로고    scopus 로고
    • The significance of the persistent presence of acid-fast bacilli in sputum smears in pulmonary tuberculosis
    • Al-Moamary MS, Black W, Bessuille E, Elwood RK, Vedal S, (1999) The significance of the persistent presence of acid-fast bacilli in sputum smears in pulmonary tuberculosis. Chest 116: 726-731.
    • (1999) Chest , vol.116 , pp. 726-731
    • Al-Moamary, M.S.1    Black, W.2    Bessuille, E.3    Elwood, R.K.4    Vedal, S.5
  • 30
    • 0030724355 scopus 로고    scopus 로고
    • Comparison of PCR, culture, and histopathology for diagnosis of tuberculous pericarditis
    • Cegielski JP, Devlin BH, Morris AJ, Kitinya JN, Pulipaka UP, et al. (1997) Comparison of PCR, culture, and histopathology for diagnosis of tuberculous pericarditis. J Clin Microbiol 35: 3254-3257.
    • (1997) J Clin Microbiol , vol.35 , pp. 3254-3257
    • Cegielski, J.P.1    Devlin, B.H.2    Morris, A.J.3    Kitinya, J.N.4    Pulipaka, U.P.5
  • 31
    • 34248163876 scopus 로고    scopus 로고
    • Immunohistochemical localization of Mycobacterium tuberculosis complex antigen with antibody to 38 kDa antigen versus Ziehl Neelsen staining in tissue granulomas of extrapulmonary tuberculosis
    • Goel MM, Budhwar P, (2007) Immunohistochemical localization of Mycobacterium tuberculosis complex antigen with antibody to 38 kDa antigen versus Ziehl Neelsen staining in tissue granulomas of extrapulmonary tuberculosis. Indian J Tuberc 54: 24-29.
    • (2007) Indian J Tuberc , vol.54 , pp. 24-29
    • Goel, M.M.1    Budhwar, P.2
  • 32
    • 0027384543 scopus 로고
    • Comparison of Ziehl-Neelsen staining and immunohistochemistry for the detection of Mycobacterium bovis in bovine and caprine tuberculous lesions
    • Gutierrez Cancela MM, Garcia Marin JF, (1993) Comparison of Ziehl-Neelsen staining and immunohistochemistry for the detection of Mycobacterium bovis in bovine and caprine tuberculous lesions. J Comp Pathol 109: 361-370.
    • (1993) J Comp Pathol , vol.109 , pp. 361-370
    • Gutierrez Cancela, M.M.1    Garcia Marin, J.F.2
  • 33
    • 0031861809 scopus 로고    scopus 로고
    • AFB staining in cytodiagnosis of tuberculosis without classical features: a comparison of Ziehl-Neelsen and fluorescent methods
    • Kumar N, Tiwari MC, Verma K, (1998) AFB staining in cytodiagnosis of tuberculosis without classical features: a comparison of Ziehl-Neelsen and fluorescent methods. Cytopathology 9: 208-214.
    • (1998) Cytopathology , vol.9 , pp. 208-214
    • Kumar, N.1    Tiwari, M.C.2    Verma, K.3
  • 34
    • 0031827231 scopus 로고    scopus 로고
    • Simultaneous detection and strain differentiation of Mycobacterium tuberculosis complex in paraffin wax embedded tissues and in stained microscopic preparations
    • van der Zanden AG, Hoentjen AH, Heilmann FG, Weltevreden EF, Schouls LM, et al. (1998) Simultaneous detection and strain differentiation of Mycobacterium tuberculosis complex in paraffin wax embedded tissues and in stained microscopic preparations. Mol Pathol 51: 209-214.
    • (1998) Mol Pathol , vol.51 , pp. 209-214
    • van der Zanden, A.G.1    Hoentjen, A.H.2    Heilmann, F.G.3    Weltevreden, E.F.4    Schouls, L.M.5
  • 36
    • 0037422617 scopus 로고    scopus 로고
    • Expression of Th1-mediated immunity in mouse lungs induces a Mycobacterium tuberculosis transcription pattern characteristic of nonreplicating persistence
    • Shi L, Jung YJ, Tyagi S, Gennaro ML, North RJ, (2003) Expression of Th1-mediated immunity in mouse lungs induces a Mycobacterium tuberculosis transcription pattern characteristic of nonreplicating persistence. Proc Natl Acad Sci U S A 100: 241-246.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 241-246
    • Shi, L.1    Jung, Y.J.2    Tyagi, S.3    Gennaro, M.L.4    North, R.J.5
  • 39
    • 33747603012 scopus 로고    scopus 로고
    • Fluorescence versus conventional sputum smear microscopy for tuberculosis: a systematic review
    • Steingart KR, Henry M, Ng V, Hopewell PC, Ramsay A, et al. (2006) Fluorescence versus conventional sputum smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis 6: 570-581.
    • (2006) Lancet Infect Dis , vol.6 , pp. 570-581
    • Steingart, K.R.1    Henry, M.2    Ng, V.3    Hopewell, P.C.4    Ramsay, A.5
  • 40
    • 33747151374 scopus 로고    scopus 로고
    • Evaluation of in situ methods used to detect Mycobacterium avium subsp. paratuberculosis in samples from patients with Crohn's disease
    • Jeyanathan M, Alexander DC, Turenne CY, Girard C, Behr MA, (2006) Evaluation of in situ methods used to detect Mycobacterium avium subsp. paratuberculosis in samples from patients with Crohn's disease. J Clin Microbiol 44: 2942-2950.
    • (2006) J Clin Microbiol , vol.44 , pp. 2942-2950
    • Jeyanathan, M.1    Alexander, D.C.2    Turenne, C.Y.3    Girard, C.4    Behr, M.A.5
  • 41
    • 38449084260 scopus 로고    scopus 로고
    • Progression of pulmonary tuberculosis and efficiency of bacillus Calmette-Guerin vaccination are genetically controlled via a common sst1-mediated mechanism of innate immunity
    • Yan BS, Pichugin AV, Jobe O, Helming L, Eruslanov EB, et al. (2007) Progression of pulmonary tuberculosis and efficiency of bacillus Calmette-Guerin vaccination are genetically controlled via a common sst1-mediated mechanism of innate immunity. J Immunol 179: 6919-6932.
    • (2007) J Immunol , vol.179 , pp. 6919-6932
    • Yan, B.S.1    Pichugin, A.V.2    Jobe, O.3    Helming, L.4    Eruslanov, E.B.5
  • 42
    • 59149091708 scopus 로고    scopus 로고
    • Multigenic control of tuberculosis resistance: analysis of a QTL on mouse chromosome 7 and its synergism with sst1
    • Sissons J, Yan BS, Pichugin AV, Kirby A, Daly MJ, et al. (2009) Multigenic control of tuberculosis resistance: analysis of a QTL on mouse chromosome 7 and its synergism with sst1. Genes Immun 10: 37-46.
    • (2009) Genes Immun , vol.10 , pp. 37-46
    • Sissons, J.1    Yan, B.S.2    Pichugin, A.V.3    Kirby, A.4    Daly, M.J.5
  • 43
    • 0037310195 scopus 로고    scopus 로고
    • Rapid in vivo screening of experimental drugs for tuberculosis using gamma interferon gene-disrupted mice
    • Lenaerts AJ, Gruppo V, Brooks JV, Orme IM, (2003) Rapid in vivo screening of experimental drugs for tuberculosis using gamma interferon gene-disrupted mice. Antimicrob Agents Chemother 47: 783-785.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 783-785
    • Lenaerts, A.J.1    Gruppo, V.2    Brooks, J.V.3    Orme, I.M.4
  • 44
    • 19544364888 scopus 로고    scopus 로고
    • Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models
    • Lenaerts AJ, Gruppo V, Marietta KS, Johnson CM, Driscoll DK, et al. (2005) Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models. Antimicrob Agents Chemother 49: 2294-2301.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 2294-2301
    • Lenaerts, A.J.1    Gruppo, V.2    Marietta, K.S.3    Johnson, C.M.4    Driscoll, D.K.5
  • 45
    • 55849117720 scopus 로고    scopus 로고
    • Metronidazole lacks antibacterial activity in guinea pigs infected with Mycobacterium tuberculosis
    • Hoff DR, Caraway ML, Brooks EJ, Driver ER, Ryan GJ, et al. (2008) Metronidazole lacks antibacterial activity in guinea pigs infected with Mycobacterium tuberculosis. Antimicrob Agents Chemother 52: 4137-4140.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 4137-4140
    • Hoff, D.R.1    Caraway, M.L.2    Brooks, E.J.3    Driver, E.R.4    Ryan, G.J.5
  • 46
    • 0027360333 scopus 로고
    • An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
    • Flynn JL, Chan J, Triebold KJ, Dalton DK, Stewart TA, et al. (1993) An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J Exp Med 178: 2249.
    • (1993) J Exp Med , vol.178 , pp. 2249
    • Flynn, J.L.1    Chan, J.2    Triebold, K.J.3    Dalton, D.K.4    Stewart, T.A.5
  • 48
    • 0035838272 scopus 로고    scopus 로고
    • Inflammation and lymphocyte activation during mycobacterial infection in the interferon-γ-deficient mouse
    • Pearl JE, Saunders B, Ehlers S, Orme IM, Cooper AM, (2001) Inflammation and lymphocyte activation during mycobacterial infection in the interferon-γ-deficient mouse. Cellular Immunology 211: 43-50.
    • (2001) Cellular Immunology , vol.211 , pp. 43-50
    • Pearl, J.E.1    Saunders, B.2    Ehlers, S.3    Orme, I.M.4    Cooper, A.M.5
  • 50
    • 25844444106 scopus 로고    scopus 로고
    • Oral therapy using nanoparticle encapsulated anti-tuberculosis drugs in guinea pigs infected with Mycobacterium tuberculosis
    • Johnson CM, Pandey R, Sharma S, Khuller GK, Basaraba RJ, et al. (2005) Oral therapy using nanoparticle encapsulated anti-tuberculosis drugs in guinea pigs infected with Mycobacterium tuberculosis. Antimicrob Agents Chemother.
    • (2005) Antimicrob Agents Chemother
    • Johnson, C.M.1    Pandey, R.2    Sharma, S.3    Khuller, G.K.4    Basaraba, R.J.5
  • 51
    • 0038520776 scopus 로고    scopus 로고
    • Hematogenous reseeding of the lung in low-dose, aerosol-infected guinea pigs: unique features of the host-pathogen interface in secondary tubercles
    • McMurray DN, (2003) Hematogenous reseeding of the lung in low-dose, aerosol-infected guinea pigs: unique features of the host-pathogen interface in secondary tubercles. Tuberculosis (Edinb) 83: 131-134.
    • (2003) Tuberculosis (Edinb) , vol.83 , pp. 131-134
    • McMurray, D.N.1
  • 52
    • 33748048512 scopus 로고    scopus 로고
    • Pulmonary lymphatics are primary sites of Mycobacterium tuberculosis infection in guinea pigs infected by aerosol
    • Basaraba RJ, Smith EE, Shanley CA, Orme IM, (2006) Pulmonary lymphatics are primary sites of Mycobacterium tuberculosis infection in guinea pigs infected by aerosol. Infect Immun 74: 5397-5401.
    • (2006) Infect Immun , vol.74 , pp. 5397-5401
    • Basaraba, R.J.1    Smith, E.E.2    Shanley, C.A.3    Orme, I.M.4
  • 54
    • 0038520795 scopus 로고    scopus 로고
    • The mouse as a useful model of tuberculosis
    • Orme IM, (2003) The mouse as a useful model of tuberculosis. Tuberculosis (Edinb) 83: 112-115.
    • (2003) Tuberculosis (Edinb) , vol.83 , pp. 112-115
    • Orme, I.M.1
  • 55
    • 3343001838 scopus 로고    scopus 로고
    • Isoniazid pharmacokinetics-pharmacodynamics in an aerosol infection model of tuberculosis
    • Jayaram R, Shandil RK, Gaonkar S, Kaur P, Suresh BL, et al. (2004) Isoniazid pharmacokinetics-pharmacodynamics in an aerosol infection model of tuberculosis. Antimicrob Agents Chemother 48: 2951-2957.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2951-2957
    • Jayaram, R.1    Shandil, R.K.2    Gaonkar, S.3    Kaur, P.4    Suresh, B.L.5
  • 56
    • 0037662753 scopus 로고    scopus 로고
    • Pharmacokinetics-pharmacodynamics of rifampin in an aerosol infection model of tuberculosis
    • Jayaram R, Gaonkar S, Kaur P, Suresh BL, Mahesh BN, et al. (2003) Pharmacokinetics-pharmacodynamics of rifampin in an aerosol infection model of tuberculosis. Antimicrob Agents Chemother 47: 2118-2124.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2118-2124
    • Jayaram, R.1    Gaonkar, S.2    Kaur, P.3    Suresh, B.L.4    Mahesh, B.N.5
  • 58
    • 0036097345 scopus 로고    scopus 로고
    • Immunological and pathological comparative anaylsis between experimental latent tuberculous infection and progressive pulmonary tuberculosis
    • Arriaga AK, Orozco EH, Aguilar LD, Rook GAW, Pando RH, (2002) Immunological and pathological comparative anaylsis between experimental latent tuberculous infection and progressive pulmonary tuberculosis. Clin Exp Immunol 128: 229-237.
    • (2002) Clin Exp Immunol , vol.128 , pp. 229-237
    • Arriaga, A.K.1    Orozco, E.H.2    Aguilar, L.D.3    Rook, G.A.W.4    Pando, R.H.5
  • 59
    • 0035092597 scopus 로고    scopus 로고
    • Disease model: pulmonary tuberculosis
    • McMurray DN, (2001) Disease model: pulmonary tuberculosis. Trends Mol Med 7: 135-137.
    • (2001) Trends Mol Med , vol.7 , pp. 135-137
    • McMurray, D.N.1
  • 60
    • 0034702247 scopus 로고    scopus 로고
    • A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis
    • Stover CK, Warrener P, VanDevanter DR, Sherman DR, Arain TM, et al. (2000) A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis. Nature 405: 962-966.
    • (2000) Nature , vol.405 , pp. 962-966
    • Stover, C.K.1    Warrener, P.2    VanDevanter, D.R.3    Sherman, D.R.4    Arain, T.M.5
  • 61
    • 70349330225 scopus 로고    scopus 로고
    • Biphasic kill curve of isoniazid reveals the presence of drug-tolerant, not drug-resistant, Mycobacterium tuberculosis in the guinea pig
    • Ahmad Z, Klinkenberg LG, Pinn ML, Fraig MM, Peloquin CA, et al. (2009) Biphasic kill curve of isoniazid reveals the presence of drug-tolerant, not drug-resistant, Mycobacterium tuberculosis in the guinea pig. Journal of Infectious Diseases 200: 1136-1143.
    • (2009) Journal of Infectious Diseases , vol.200 , pp. 1136-1143
    • Ahmad, Z.1    Klinkenberg, L.G.2    Pinn, M.L.3    Fraig, M.M.4    Peloquin, C.A.5
  • 62
    • 17144386211 scopus 로고    scopus 로고
    • Ipr1 gene mediates innate immunity to tuberculosis
    • Pan H, Yan BS, Rojas M, Shebzukhov YV, Zhou H, et al. (2005) Ipr1 gene mediates innate immunity to tuberculosis. Nature 434: 767-772.
    • (2005) Nature , vol.434 , pp. 767-772
    • Pan, H.1    Yan, B.S.2    Rojas, M.3    Shebzukhov, Y.V.4    Zhou, H.5
  • 63
    • 70350322939 scopus 로고    scopus 로고
    • Noninvasive pulmonary [18F]-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment
    • Davis SL, Nuermberger EL, Um PK, Vidal C, Jedynak B, et al. (2009) Noninvasive pulmonary [18F]-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment. Antimicrobial Agents & Chemotherapy 53: 4879-4884.
    • (2009) Antimicrobial Agents & Chemotherapy , vol.53 , pp. 4879-4884
    • Davis, S.L.1    Nuermberger, E.L.2    Um, P.K.3    Vidal, C.4    Jedynak, B.5
  • 64
    • 77956299896 scopus 로고    scopus 로고
    • Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigs
    • Gil O, Díaz I, Vilaplana C, Tapia G, Díaz J, et al. (2010) Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigs. PLoS ONE 5: e10030.
    • (2010) PLoS ONE , vol.5
    • Gil, O.1    Díaz, I.2    Vilaplana, C.3    Tapia, G.4    Díaz, J.5
  • 65
    • 69049108875 scopus 로고    scopus 로고
    • Foamy macrophages and the progression of the human tuberculosis granuloma
    • Russell DG, Cardona PJ, Kim MJ, Allain S, Altare F, (2009) Foamy macrophages and the progression of the human tuberculosis granuloma. Nat Immunol 10: 943-948.
    • (2009) Nat Immunol , vol.10 , pp. 943-948
    • Russell, D.G.1    Cardona, P.J.2    Kim, M.J.3    Allain, S.4    Altare, F.5
  • 66
    • 33947711645 scopus 로고    scopus 로고
    • New insights on the nature of latent tuberculosis infection and its treatment
    • Cardona PJ, (2007) New insights on the nature of latent tuberculosis infection and its treatment. Inflamm Allergy Drug Targets 6: 27-39.
    • (2007) Inflamm Allergy Drug Targets , vol.6 , pp. 27-39
    • Cardona, P.J.1
  • 67
    • 57149096869 scopus 로고    scopus 로고
    • Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence
    • Peyron P, Vaubourgeix J, Poquet Y, Levillain F, Botanch C, et al. (2008) Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence. PLoS Pathog 4: e1000204.
    • (2008) PLoS Pathog , vol.4
    • Peyron, P.1    Vaubourgeix, J.2    Poquet, Y.3    Levillain, F.4    Botanch, C.5
  • 68
    • 0029976980 scopus 로고    scopus 로고
    • An in vitro model for sequential study of shiftdown of mycobacterium tuberculosis through two stages of nonreplicating persistence
    • Wayne LG, Hayes LG, (1996) An in vitro model for sequential study of shiftdown of mycobacterium tuberculosis through two stages of nonreplicating persistence. infect immun 64: 2062-2069.
    • (1996) Infect Immun , vol.64 , pp. 2062-2069
    • Wayne, L.G.1    Hayes, L.G.2
  • 69
    • 41449106119 scopus 로고    scopus 로고
    • Cytokine profiles in primary and secondary pulmonary granulomas of Guinea pigs with tuberculosis
    • Ly LH, Russell MI, McMurray DN, (2008) Cytokine profiles in primary and secondary pulmonary granulomas of Guinea pigs with tuberculosis. Am J Respir Cell Mol Biol 38: 455-462.
    • (2008) Am J Respir Cell Mol Biol , vol.38 , pp. 455-462
    • Ly, L.H.1    Russell, M.I.2    McMurray, D.N.3
  • 70
    • 45149110879 scopus 로고    scopus 로고
    • Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harboring drug tolerant bacteria
    • Aea Ojha, In Press
    • Aea Ojha, (2008) Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harboring drug tolerant bacteria. Molecular Microbiology In Press.
    • (2008) Molecular Microbiology
  • 71
    • 61649103963 scopus 로고    scopus 로고
    • Evolution of foamy macrophages in the pulmonary granulomas of experimental tuberculosis models
    • Cáceres N, Tapia G, Ojanguren I, Altare F, Gil O, Pinto S, et al. (2009) Evolution of foamy macrophages in the pulmonary granulomas of experimental tuberculosis models. Tuberculosis 89: 175-182.
    • (2009) Tuberculosis , vol.89 , pp. 175-182
    • Cáceres, N.1    Tapia, G.2    Ojanguren, I.3    Altare, F.4    Gil, O.5    Pinto, S.6
  • 72
    • 67349260111 scopus 로고    scopus 로고
    • A dynamic reinfection hypothesis of latent tuberculosis infection
    • Cardona P, (2009) A dynamic reinfection hypothesis of latent tuberculosis infection. Infection 37: 80-86.
    • (2009) Infection , vol.37 , pp. 80-86
    • Cardona, P.1
  • 73
    • 0025996858 scopus 로고
    • A guinea pig model of experimental airborne tuberculosis for evaluation of the response to chemotherapy: the effect on bacilli in the initial phase of treatment
    • Smith DW, Balasubramanian V, Wiegeshaus E, (1991) A guinea pig model of experimental airborne tuberculosis for evaluation of the response to chemotherapy: the effect on bacilli in the initial phase of treatment. Tubercle 72: 223-231.
    • (1991) Tubercle , vol.72 , pp. 223-231
    • Smith, D.W.1    Balasubramanian, V.2    Wiegeshaus, E.3
  • 76
    • 11744352331 scopus 로고
    • Fluorescence of auramine O in the presence of nucleic acid
    • Oster G, (1951) [Fluorescence of auramine O in the presence of nucleic acid.]. C R Hebd Seances Acad Sci 232: 1708-1710.
    • (1951) C R Hebd Seances Acad Sci , vol.232 , pp. 1708-1710
    • Oster, G.1
  • 77
    • 0242552007 scopus 로고    scopus 로고
    • Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection
    • Seiler P, Ulrichs T, Bandermann S, Pradl L, Jorg S, et al. (2003) Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection. J Infect Dis 188: 1326-1331.
    • (2003) J Infect Dis , vol.188 , pp. 1326-1331
    • Seiler, P.1    Ulrichs, T.2    Bandermann, S.3    Pradl, L.4    Jorg, S.5
  • 78
    • 20244371528 scopus 로고    scopus 로고
    • Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue
    • Ulrichs T, Lefmann M, Reich M, Morawietz L, Roth A, et al. (2005) Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue. J Pathol 205: 633-640.
    • (2005) J Pathol , vol.205 , pp. 633-640
    • Ulrichs, T.1    Lefmann, M.2    Reich, M.3    Morawietz, L.4    Roth, A.5
  • 79
    • 31144446585 scopus 로고    scopus 로고
    • New insights into the function of granulomas in human tuberculosis
    • Ulrichs T, Kaufmann SH, (2006) New insights into the function of granulomas in human tuberculosis. J Pathol 208: 261-269.
    • (2006) J Pathol , vol.208 , pp. 261-269
    • Ulrichs, T.1    Kaufmann, S.H.2
  • 81
  • 83
    • 74949135138 scopus 로고    scopus 로고
    • Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary tuberculosis
    • Eum SY, Kong JH, Hong MS, Lee YJ, Kim JH, et al. (2009) Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary tuberculosis. Chest 137: 122-128.
    • (2009) Chest , vol.137 , pp. 122-128
    • Eum, S.Y.1    Kong, J.H.2    Hong, M.S.3    Lee, Y.J.4    Kim, J.H.5
  • 84
    • 7044235500 scopus 로고    scopus 로고
    • The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M. tuberculosis-infected guinea pigs
    • Brandt L, Skeiky YA, Alderson MR, Lobet Y, Dalemans W, et al. (2004) The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M. tuberculosis-infected guinea pigs. Infect Immun 72: 6622-6632.
    • (2004) Infect Immun , vol.72 , pp. 6622-6632
    • Brandt, L.1    Skeiky, Y.A.2    Alderson, M.R.3    Lobet, Y.4    Dalemans, W.5
  • 85
    • 0031724157 scopus 로고    scopus 로고
    • Evaluation of once-weekly therapy for tuberculosis using isoniazid plus rifamycins in the mouse aerosol infection model
    • Brooks JV, Orme IM, (1998) Evaluation of once-weekly therapy for tuberculosis using isoniazid plus rifamycins in the mouse aerosol infection model. Antimicrob Agents Chemother 42: 3047-3048.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 3047-3048
    • Brooks, J.V.1    Orme, I.M.2
  • 86
    • 4644359212 scopus 로고    scopus 로고
    • Magnetic resonance imaging of pulmonary lesions in guinea pigs infected with Mycobacterium tuberculosis
    • Kraft SL, Dailey D, Kovach M, Stasiak KL, Bennett J, et al. (2004) Magnetic resonance imaging of pulmonary lesions in guinea pigs infected with Mycobacterium tuberculosis. Infect Immun 72: 5963-5971.
    • (2004) Infect Immun , vol.72 , pp. 5963-5971
    • Kraft, S.L.1    Dailey, D.2    Kovach, M.3    Stasiak, K.L.4    Bennett, J.5


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