메뉴 건너뛰기




Volumn 33, Issue 3, 2015, Pages 420-425

TGR5 in the cholangiociliopathies

Author keywords

Cholangiociliopathies; Cholangiocytes; Cilia; Hepatic cysts; Polycystic liver disease

Indexed keywords

CYCLIC AMP; FIBROCYSTIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 5; POLYCYSTIN 1; POLYCYSTIN 2; UNCLASSIFIED DRUG; GPBAR1 PROTEIN, HUMAN;

EID: 84930579735     PISSN: 02572753     EISSN: 14219875     Source Type: Journal    
DOI: 10.1159/000371696     Document Type: Conference Paper
Times cited : (27)

References (36)
  • 2
    • 84896988246 scopus 로고    scopus 로고
    • TGR5 in inflammation and cardiovascular disease
    • Pols TW: TGR5 in inflammation and cardiovascular disease. Biochem Soc Trans 2014; 42: 244-249.
    • (2014) Biochem Soc Trans , vol.42 , pp. 244-249
    • Pols, T.W.1
  • 3
    • 84895520482 scopus 로고    scopus 로고
    • The bile acid TGR5 membrane receptor: From basic research to clinical application
    • Duboc H, Tache Y, Hofmann AF: The bile acid TGR5 membrane receptor: from basic research to clinical application. Dig Liver Dis 2014; 46: 302-312.
    • (2014) Dig Liver Dis , vol.46 , pp. 302-312
    • Duboc, H.1    Tache, Y.2    Hofmann, A.F.3
  • 6
    • 70349255713 scopus 로고    scopus 로고
    • The membranebound bile acid receptor TGR5 is localized in the epithelium of human gallbladders
    • Keitel V, Cupisti K, Ullmer C, Knoefel WT, Kubitz R, Haussinger D: The membranebound bile acid receptor TGR5 is localized in the epithelium of human gallbladders. Hepatology 2009; 50: 861-870.
    • (2009) Hepatology , vol.50 , pp. 861-870
    • Keitel, V.1    Cupisti, K.2    Ullmer, C.3    Knoefel, W.T.4    Kubitz, R.5    Haussinger, D.6
  • 8
    • 33846345695 scopus 로고    scopus 로고
    • Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells
    • Yasuda H, Hirata S, Inoue K, Mashima H, Ohnishi H, Yoshiba M: Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells. Biochem Biophys Res Commun 2007; 354: 154-159.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 154-159
    • Yasuda, H.1    Hirata, S.2    Inoue, K.3    Mashima, H.4    Ohnishi, H.5    Yoshiba, M.6
  • 9
    • 77949425951 scopus 로고    scopus 로고
    • TGR5 as a therapeutic target for treating obesity
    • Zhong M: TGR5 as a therapeutic target for treating obesity. Curr Top Med Chem 2010; 10: 386-396.
    • (2010) Curr Top Med Chem , vol.10 , pp. 386-396
    • Zhong, M.1
  • 11
    • 67349288052 scopus 로고    scopus 로고
    • TGR5: An emerging bile acid G-protein-coupled receptor target for the potential treatment of metabolic disorders
    • Tiwari A, Maiti P: TGR5: an emerging bile acid G-protein-coupled receptor target for the potential treatment of metabolic disorders. Drug Discov Today 2009; 14: 523-530.
    • (2009) Drug Discov Today , vol.14 , pp. 523-530
    • Tiwari, A.1    Maiti, P.2
  • 13
    • 84880907693 scopus 로고    scopus 로고
    • The bile acid membrane receptor TGR5: A novel pharmacological target in metabolic, inflammatory and neoplastic disorders
    • Stepanov V, Stankov K, Mikov M: The bile acid membrane receptor TGR5: A novel pharmacological target in metabolic, inflammatory and neoplastic disorders. J Recept Signal Transduct Res 2013; 33: 213-223.
    • (2013) J Recept Signal Transduct Res , vol.33 , pp. 213-223
    • Stepanov, V.1    Stankov, K.2    Mikov, M.3
  • 14
    • 84939815585 scopus 로고    scopus 로고
    • TGR5: Pathogenetic role and/or therapeutic target in fibrosing cholangitis
    • Epub ahead of print
    • Keitel V, Reich M, Haussinger D: TGR5: pathogenetic role and/or therapeutic target in fibrosing cholangitis? Clin Rev Allergy Immunol 2014, Epub ahead of print.
    • (2014) Clin Rev Allergy Immunol
    • Keitel, V.1    Reich, M.2    Haussinger, D.3
  • 15
    • 49449094484 scopus 로고    scopus 로고
    • Cholangiocyte primary cilia in liver health and disease
    • Masyuk AI, Masyuk TV, LaRusso NF: Cholangiocyte primary cilia in liver health and disease. Dev Dyn 2008; 237: 2007-2012.
    • (2008) Dev Dyn , vol.237 , pp. 2007-2012
    • Masyuk, A.I.1    Masyuk, T.V.2    Larusso, N.F.3
  • 16
    • 67651101020 scopus 로고    scopus 로고
    • Cholangiociliopathies: Genetics, molecular mechanisms and potential therapies
    • Masyuk T, Masyuk A, LaRusso N: Cholangiociliopathies: genetics, molecular mechanisms and potential therapies. Curr Opin Gastroenterol 2009; 25: 265-271.
    • (2009) Curr Opin Gastroenterol , vol.25 , pp. 265-271
    • Masyuk, T.1    Masyuk, A.2    Larusso, N.3
  • 17
    • 84891818486 scopus 로고    scopus 로고
    • Strategies targeting cAMP signaling in the treatment of polycystic kidney disease
    • Torres VE, Harris PC: Strategies targeting cAMP signaling in the treatment of polycystic kidney disease. J Am So Nephrol 2014; 25: 18-32.
    • (2014) J Am so Nephrol , vol.25 , pp. 18-32
    • Torres, V.E.1    Harris, P.C.2
  • 18
    • 84869471263 scopus 로고    scopus 로고
    • Polycystic liver disease: A clinical review
    • Chandok N: Polycystic liver disease: A clinical review. Ann Hepatol 2012; 11: 819-826.
    • (2012) Ann Hepatol , vol.11 , pp. 819-826
    • Chandok, N.1
  • 19
    • 84901500059 scopus 로고    scopus 로고
    • Polycystic liver disease: An overview of pathogenesis, clinical manifestations and management
    • Cnossen WR, Drenth JP: Polycystic liver disease: an overview of pathogenesis, clinical manifestations and management. Orphanet J Rare Dis 2014; 9: 69.
    • (2014) Orphanet J Rare Dis , vol.9 , pp. 69
    • Cnossen, W.R.1    Drenth, J.P.2
  • 20
    • 67249091839 scopus 로고    scopus 로고
    • Polycystic kidney disease
    • Harris PC, Torres VE: Polycystic kidney disease. Annu Rev Med 2009; 60: 321-337.
    • (2009) Annu Rev Med , vol.60 , pp. 321-337
    • Harris, P.C.1    Torres, V.E.2
  • 21
    • 33646595633 scopus 로고    scopus 로고
    • Polycystic liver disease: New insights into disease pathogenesis
    • Masyuk T, LaRusso N: Polycystic liver disease: new insights into disease pathogenesis. Hepatology 2006; 43: 906-908.
    • (2006) Hepatology , vol.43 , pp. 906-908
    • Masyuk, T.1    Larusso, N.2
  • 23
    • 79958081521 scopus 로고    scopus 로고
    • Polycystic liver diseases: Congenital disorders of cholangiocyte signaling
    • 1859. e1
    • Strazzabosco M, Somlo S: Polycystic liver diseases: congenital disorders of cholangiocyte signaling. Gastroenterology 2011; 140: 1855-1859, 1859. e1.
    • (2011) Gastroenterology , vol.140 , pp. 1855-1859
    • Strazzabosco, M.1    Somlo, S.2
  • 24
    • 84899929999 scopus 로고    scopus 로고
    • Polycystic liver disease: Ductal plate malformation and the primary cilium
    • Wills ES, Roepman R, Drenth JP: Polycystic liver disease: ductal plate malformation and the primary cilium. Trends Mol Med 2014; 20: 261-270.
    • (2014) Trends Mol Med , vol.20 , pp. 261-270
    • Wills, E.S.1    Roepman, R.2    Drenth, J.P.3
  • 25
    • 33745710680 scopus 로고    scopus 로고
    • Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling
    • Masyuk AI, Masyuk TV, Splinter PL, Huang BQ, Stroope AJ, LaRusso NF: Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling. Gastroenterology 2006; 131: 911-920.
    • (2006) Gastroenterology , vol.131 , pp. 911-920
    • Masyuk, A.I.1    Masyuk, T.V.2    Splinter, P.L.3    Huang, B.Q.4    Stroope, A.J.5    Larusso, N.F.6
  • 26
    • 57149107141 scopus 로고    scopus 로고
    • Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease
    • Banales JM, Masyuk TV, Bogert PS, Huang BQ, Gradilone SA, Lee SO, Stroope AJ, Masyuk AI, Medina JF, LaRusso NF: Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease. Am J Pathol 2008; 173: 1637-1646.
    • (2008) Am J Pathol , vol.173 , pp. 1637-1646
    • Banales, J.M.1    Masyuk, T.V.2    Bogert, P.S.3    Huang, B.Q.4    Gradilone, S.A.5    Lee, S.O.6    Stroope, A.J.7    Masyuk, A.I.8    Medina, J.F.9    Larusso, N.F.10
  • 27
    • 58949089448 scopus 로고    scopus 로고
    • The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD)
    • Banales JM, Masyuk TV, Gradilone SA, Masyuk AI, Medina JF, LaRusso NF: The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD). Hepatology 2009; 49: 160-174.
    • (2009) Hepatology , vol.49 , pp. 160-174
    • Banales, J.M.1    Masyuk, T.V.2    Gradilone, S.A.3    Masyuk, A.I.4    Medina, J.F.5    Larusso, N.F.6
  • 32
    • 33947315462 scopus 로고    scopus 로고
    • Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine ,5 -cyclic monophosphate
    • Masyuk TV, Masyuk AI, Torres VE, Harris PC, LaRusso NF: Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine ,5 -cyclic monophosphate. Gastroenterology 2007; 132: 1104-1116.
    • (2007) Gastroenterology , vol.132 , pp. 1104-1116
    • Masyuk, T.V.1    Masyuk, A.I.2    Torres, V.E.3    Harris, P.C.4    Larusso, N.F.5
  • 36
    • 84868360297 scopus 로고    scopus 로고
    • Perspective: TGR5 (Gpbar-1) in liver physiology and disease
    • Keitel V, Haussinger D: Perspective: TGR5 (Gpbar-1) in liver physiology and disease. Clin Res Hepatol Gastroenterol 2012; 36: 412-419.
    • (2012) Clin Res Hepatol Gastroenterol , vol.36 , pp. 412-419
    • Keitel, V.1    Haussinger, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.