Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells

Leukemia

Volumn 29, Issue 6, 2015, Pages 1279-1289

  Spencer, D H ^a   Young, M A ^a   Lamprecht, T L ^a,b   Helton, N M ^a   Fulton, R ^a   O'Laughlin, M ^a   Fronick, C ^a   Magrini, V ^a   Demeter, R T ^a   Miller, C A ^a   Klco, J M ^a,b   Wilson, R K ^a   Ley, T J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE MYELOBLASTIC LEUKEMIA; ARTICLE; BONE MARROW CELL; CANCER SURVIVAL; CHROMATIN STRUCTURE; CONTROLLED STUDY; CYTOGENETICS; DNA METHYLATION; EPIGENETICS; GENE CLUSTER; GENE CONTROL; GENE EXPRESSION; GENE FUSION; GENE LOCUS; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HEMATOPOIESIS; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; HOX GENE; HOXA GENE; HOXB GENE; HUMAN; HUMAN CELL; KARYOTYPE; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MONOCYTE; NEUTROPHIL; OVERALL SURVIVAL; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROMYELOCYTE; RNA SEQUENCE; SOMATIC MUTATION; TUMOR GENE; CASE CONTROL STUDY; CHROMOSOME ABERRATION; COMPARATIVE STUDY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SEQUENCING; HOMEOBOX; METABOLISM; MORTALITY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE;

MESSENGER RNA; TUMOR MARKER;

BIOMARKERS, TUMOR; CASE-CONTROL STUDIES; CHROMOSOME ABERRATIONS; DNA METHYLATION; EPIGENOMICS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, HOMEOBOX; HEMATOPOIETIC STEM CELLS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LEUKEMIA, MYELOID, ACUTE; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SURVIVAL RATE;

EID: 84930573440     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2015.6     Document Type: Article

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