Curcumin specifically binds to the human calcium-calmodulin-dependent protein kinase IV: Fluorescence and molecular dynamics simulation studies

Journal of Biomolecular Structure and Dynamics

Volumn 34, Issue 3, 2016, Pages 572-584

  Hoda, Nasimul ^a   Naz, Huma ^a   Jameel, Ehtesham ^b   Shandilya, Ashutosh ^c   Dey, Sharmistha ^d   Hassan, Md Imtaiyaz ^a   Ahmad, Faizan ^a   Jayaram, B ^c  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

^b B R A BIHAR UNIVERSITY   (India)

^c INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

^d ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

calcium calmodulin dependent protein kinase IV; curcumin; docking; drug target; high affinity ligand; molecular dynamics simulation

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IV; CURCUMIN; LIGAND; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG PROTEIN BINDING; FLUORESCENCE; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; STRUCTURE ANALYSIS; SURFACE PLASMON RESONANCE; BINDING SITE; CHEMISTRY; CONFORMATION; ENZYME ACTIVE SITE; HUMAN; METABOLISM; PROTEIN STABILITY; THERMODYNAMICS;

BINDING SITES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 4; CATALYTIC DOMAIN; CURCUMIN; HUMANS; HYDROGEN BONDING; LIGANDS; MOLECULAR CONFORMATION; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN STABILITY; THERMODYNAMICS;

EID: 84930532543     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2015.1046934     Document Type: Article

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