The role of Ca2+/calmodulin-dependent protein kinases within the nucleus

Cell Calcium

Volumn 23, Issue 2-3, 1998, Pages 103-114

  Heist, E Kevin ^a   Schulman, Howard ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; PROTEIN KINASE (CALCIUM,CALMODULIN); RNA; TRANSCRIPTION FACTOR; CALCIUM; CALMODULIN;

ALTERNATIVE RNA SPLICING; APOPTOSIS; CALCIUM CELL LEVEL; CELL CYCLE; CELL NUCLEUS; CELL STIMULATION; CYTOSOL; DIFFUSION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; SPIKE; SYNAPSE; ANIMAL; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; TRANSACTIVATION;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALMODULIN; CELL NUCLEUS; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS);

EID: 0031596835     PISSN: 01434160     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0143-4160(98)90108-7     Document Type: Article

References (42)

1. Bachs O., Agell N., Carafoli E. Calcium and calmodulin function in the cell nucleus. Biochim Biophys Acta 1992; 1113: 259-270.
2. Lu K.P., Nanthakumar N., Dayton J.S., Means A.R. Calcium and calmodulin regulation of the nuclear division cycle of Aspergillus nidulans. Adv Mol Cell Biol 1995; 13: 89-136.
3. Nicotera P., Zhivotovsky B., Orrenius S. Nuclear calcium transport and the role of calcium in apoptosis. Cell Calcium 1994; 16: 279-288.
4. 2+-dependent regulation in neuronal gene expression. Curr Opin Neurobiol 1997; 7: 419-429.
5. 2+] changes in nucleus and cytosol. Cell Calcium 1994; 16: 239-246.
6. 2+ in HeLa cells. J Biol Chem 1996; 271: 31210-31214.
7. Brini M., Marsault R., Bastianutto C., Pozzan T., Rizzuto R. Nuclear targeting of aequorin. Cell Calcium 1994; 16: 259-268.
8. 2+/calmodulin-dependent protein kinases. Annu Rev Biochem 1992; 61: 559-601.
9. Braun A.P., Schulman H. The multifunctional calcium/calmodulin-dependent protein kinase: from form to function. Annu Rev Physiol 1995; 57: 417-445.
10. 2+/calmodulin-dependent protein kinases. In: Carafoli E., Klee C. eds Calcium as a Cellular Regulator. New York: Oxford University Press, In press.
11. 2+/calmodulin-dependent protein kinase I from bovine brain. J Biol Chem 1987; 262: 7273-7281.
12. Srinivasan M., Edman C., Schulman H. Alternative splicing introduces a nuclear localization signal that targets multifunctional CaM kinase to the nucleus. J Cell Biol 1994; 126: 839-852.
13. 2+/calmodulin-dependent protein kinase IV in the rat central nervous system: light and electron microscopic observations. Neuroscience 1995; 68: 181-194.
14. 2+/calmodulin-dependent protein kinases type I, II, and IV. J Biol Chem 1996; 271: 3066-3073.
15. Shimomura A., Ogawa Y., Kitani T., Fujisawa H., Hagiwara M. Calmodulin-dependent protein kinase II potentiates transcriptional activation through activating transcription factor I but not cAMP response element-binding protein. J Biol Chem 1996; 271: 17957-17960.
16. Heist E.K., Srinivasan M., Schulman H. Phosphorylation by CaM kinase I or CaM kinase IV blocks nuclear targeting of CaM kinase II. Submitted.
17. Connor J.A. Intracellular calcium mobilization by inositol 1,4,5-trisphosphate: intracellular movements and compartmentalization. Cell Calcium 1993; 14: 185-200.
18. Allbritton N.L., Oancea E., Kuhn M.A., Meyer T. Source of nuclear calcium signals. Proc Natl Acad Sci USA 1994; 91 : 12458-12462.
19. 2+ transients and meiosis resumption in starfish oocytes are mimicked by the nuclear injection of inositol 1,4,5-trisphosphate and cADP-ribose. Cell Calcium 1997; 22: 11-20.
20. Divecha N., Irvine R.F. Phospholipid signaling. Cell 1995; 80: 269-278.
21. Malviya A. N. The nuclear inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate receptors. Cell Calcium 1994; 16: 301-313.
22. Bachs O., Agell N., Carafoli E. Calmodulin and calmodulin-binding proteins in the nucleus. Cell Calcium 1994; 16: 289-296.
23. Serratosa J., Pujol M.J., Bachs O., Carafoli E. Rearrangement of nuclear calmodulin during proliferative liver cell activation. Biochem Biophys Res Commun 1988; 150: 1162-1169.
24. Portoles M., Faura M., Renau-Piqueras J. et al. Nuclear calmodulin/62 kDa calmodulin-binding protein complexes in interphasic and mitotic cells. J Cell Sci 1994; 107: 3601-3614.
25. Harper J.F., Cheung W.Y., Wallace R.W., Huang H.L., Levine S.L., Steiner A.L. Localization of calmodulin in rat tissues. Proc Natl Acad Sci USA 1980; 77: 366-370.
26. Vendrell M., Pujol M.J., Tusell J.M., Serratosa J. Effect of different conduisants on calmodulin levels and proto-oncogene c-fos expression in the central nervous system. Mol Brain Res 1992; 14: 285-292.
27. 2+-regulated dynamic compartmentalization of calmodulin in living smooth muscle cells. J Biol Chem 1995; 270: 21532-21538.
28. Deisseroth K., Heist E.K., Tsien R.W. Nuclear translocation of calmodulin triggers activity-dependent CREB phosphorylation in hippocampal neurons. Nature In press.
29. 2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes Dev 1994; 8: 2527-2539.
30. Hanson P.I., Meyer T., Stryer L., Schulman H. Dual role of calmodulin in autophosphorylation of multifunctional CaM kinase may underlie decoding of calcium signals. Neuron 1994; 12: 943-956.
31. 2+/calmodulin-dependent protein kinase II by inter- and intrasubunitcatalyzed autophosphorylations. J Biol Chem 1994; 269: 13744-13747
32. Meyer T., Hanson P.I., Stryer L., Schulman H. Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science 1992; 256: 1199-1201.
33. Putkey J.A., Waxham M.N. A peptide model for calmodulin trapping by calcium/calmodulin-dependent protein kinase II. J Biol Chem 1966; 271: 29619-29623.
34. 2+/calmodulin-dependent protein kinase II. Mutation of threonine 286 to alanine and aspartate. J Biol Chem 1989; 264: 16759-16763.
35. 2+/calmodulm-dependent protein kinase and mutational analysis of its autoregulation. Neuron 1989; 3: 59-70.
36. 2+-independent for functional studies. Biochemistry 1990; 29: 1679-1684.
37. Schulman H., Hanson P.I., Meyer T. Decoding calcium signals by multifunctional CaM kinase. Cell Calcium 1992; 13: 401-411.
38. 2+ oscillations. Science 1998; 279: 227-230.
39. Silver P.A. How proteins enter the nucleus. Cell 1991; 64: 489-497
40. 2+/calmodulin-dependent protein kinase II: localization in the interphase nucleus and the mitotic apparatus of mammalian cells. Proc Natl Acad Sci USA 1990; 87: 5341-5345.
41. 2+/calmodulin-dependent protein kinase isoforms in rat brain. J Neurosci 1995; 15: 6797-6808.
42. Benson D.L., Isackson P.J., Gall C.M., Jones E.G. Differential effects of monocular deprivation on glutamic acid decarboxylase and type II calcium-calmodulin dependent protein kinase gene expression in the adult monkey visual cortex. J Neurosci 1991; 11: 31-47