CREB: A key regulator of normal and neoplastic hematopoiesis

Advances in Hematology

Volumn 2009, Issue , 2009, Pages

  Sakamoto, Kathleen M ^a   Sandoval, Salemiz ^a   Pigazzi, Martina ^b  

^a MATTEL CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; CELL SURFACE RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN A1; CYCLIN D1; EARLY GROWTH RESPONSE FACTOR 1; FORSKOLIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 3; INTERLEUKIN 4; JANUS KINASE 1; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN BCL 2; PROTEIN ICER; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C EPSILON; PROTEIN P21; PROTEIN P300; PROTEIN P53; REPRESSOR PROTEIN; S6 KINASE; STAT3 PROTEIN; THROMBOPOIETIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; BONE MARROW; CANCER CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION; HEMATOPOIESIS; HUMAN; LEUKEMOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SPLEEN; TRANSGENIC MOUSE;

EID: 77953427344     PISSN: 16879104     EISSN: 16879112     Source Type: Journal    
DOI: 10.1155/2009/634292     Document Type: Review

References (63)

1. Shaywitz A. J., Greenberg M. E., CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals Annual Review of Biochemistry 1999 68 821 861
2. Mayr B., Montminy M., Transcriptional regulation by the phosphorylation-dependent factor creb Nature Reviews Molecular Cell Biology 2001 2 8 599 609 (Pubitemid 33674011)
3. Johannessen M., Delghandi M. P., Moens U., What turns CREB on? Cellular Signalling 2004 16 11 1211 1227 (Pubitemid 39165450)
4. Montminy M. R., Gonzalez G. A., Yamamoto K. K., Regulation of cAMP-inducible genes by CREB Trends in Neurosciences 1990 13 5 184 188
5. Zhang X., Odom D. T., Koo S.-H. et al., Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues Proceedings of the National Academy of Sciences of the United States of America 2005 102 12 4459 4464 (Pubitemid 40397134)
6. Conkright M. D., Canettieri G., Screaton R. et al., TORCs: transducers of regulated CREB activity Molecular Cell 2003 12 2 413 423 (Pubitemid 37238928)
7. Screaton R. A., Conkright M. D. et al., Katoh Y., The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector Cell 2004 119 1 61 74 (Pubitemid 39349320)
8. Deak M., Clifton A. D., Lucocq J. M., Alessi D. R., Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB The EMBO Journal 1998 17 15 4426 4441 (Pubitemid 28362632)
9. Wiggin G. R., Soloaga A., Foster J. M., Murray-Tait V., Cohen P., Arthur J. S. C., MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts Molecular and Cellular Biology 2002 22 8 2871 2881 (Pubitemid 34263007)
10. Kwon E. M., Raines M. A., Blenis J., Sakamoto K. M., Granulocyte- macrophage colony-stimulating factor stimulation results in phosphorylation of cAMP response element-binding protein through activation of pp90RSK Blood 2000 95 8 2552 2558 (Pubitemid 30210533)
11. Brunet A., Bonni A., Zigmond M. J. et al., Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor Cell 1999 96 6 857 868 (Pubitemid 29165088)
12. Arnould T., Vankoningsloo S., Renard P. et al., Creb activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation The EMBO Journal 2002 21 1-2 53 63 (Pubitemid 34087074)
13. Impey S., McCorkle S. R., Cha-Molstad H. et al., Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions Cell 2004 119 7 1041 1054 (Pubitemid 40037616)
14. Quinn P. G., Granner D. K., Cyclic AMP-dependent protein kinase regulates transcription of the phosphoenolpyruvate carboxykinase gene but not binding of nuclear factors to the cyclic AMP regulatory element Molecular and Cellular Biology 1990 10 7 3357 3364 (Pubitemid 20198161)
15. Liu J., Park E. A., Gurney A. L., Roesler W. J., Hanson R. W., Cyclic AMP induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription is mediated by multiple promoter elements The Journal of Biological Chemistry 1991 266 28 19095 19102 (Pubitemid 21908197)
16. Bonni A., Ginty D. D., Dudek H., Greenberg M. E., Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals Molecular and Cellular Neurosciences 1995 6 2 168 183
17. Riccio A., Ahn S., Davenport C. M., Blendy J. A., Ginty D. D., Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons Science 1999 286 5448 2358 2361 (Pubitemid 30016901)
18. Shankar D. B., Cheng J. C., Kinjo K., The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia Cancer Cell 2005 7 4 351 362 (Pubitemid 40544652)
19. Cheng J. C., Kinjo K., Judelson D. R. et al., CREB is a critical regulator of normal hematopoiesis and leukemogenesis Blood 2008 111 3 1182 1192 (Pubitemid 351213399)
20. Mora-Garcia P., Cheng J., Crans-Vargas H. N., Countouriotis A., Shankar D., Sakamoto K. M., Transcriptional regulators and myelopoiesis: the role of serum response factor and CREB as targets of cytokine signaling Stem Cells 2003 21 2 123 130 (Pubitemid 36331755)
21. Olsen R. J., Hinrichs S. H., Phosphorylation of the EWS IQ domain regulates transcriptional activity of the EWS/ATF1 and EWS/FLI1 fusion proteins Oncogene 2001 20 14 1756 1764
22. Schaefer K.-L., Brachwitz K., Wai D. H. et al., Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3 Cancer Research 2004 64 10 3395 3405 (Pubitemid 38657911)
23. Zucman J., Delattre O., Desmaze C. et al., EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts Nature Genetics 1993 4 4 341 345 (Pubitemid 23231480)
24. Antonescu C. R., Nafa K., Segal N. H., Dal Cin P., Ladanyi M., EWS-CREB1: a recurrent variant fusion in clear cell sarcomaassociation with gastrointestinal location and absence of melanocytic differentiation Clinical Cancer Research 2006 12 18 5356 5362 (Pubitemid 44497248)
25. Yin M.-J., Paulssen E. J., Seeler J.-S., Gaynor R. B., Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type I tax and CREB Journal of Virology 1995 69 6 3420 3432
26. Koga H., Ohshima T., Shimotohno K., Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3 The Journal of Biological Chemistry 2004 279 51 52978 52983 (Pubitemid 40063544)
27. Siu Y.-T., Chin K.-T., Siu K.-L., Choy E. Y. W., Jeang K.-T., Jin D.-Y., TORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeats Journal of Virology 2006 80 14 7052 7059
28. Williams J. S., Andrisani O. M., The hepatitis B virus X protein targets the basic region-leucine zipper domain of CREB Proceedings of the National Academy of Sciences of the United States of America 1995 92 9 3819 3823
29. Tonon G., Modi S., Wu L. et al., t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway Nature Genetics 2003 33 2 208 213 (Pubitemid 36177076)
30. Wu L., Liu J., Gao P. et al., Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation The EMBO Journal 2005 24 13 2391 2402 (Pubitemid 41032590)
31. Ahn S., Olive M., Aggarwal S., Krylov D., Ginty D. D., Vinson C., A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos Molecular and Cellular Biology 1998 18 2 967 977 (Pubitemid 28063431)
32. Siu Y.-T., Jin D.-Y., CREB: a real culprit in oncogenesis FEBS Journal 2007 274 13 3224 3232
33. Conkright M. D., Montminy M., CREB: the unindicted cancer co-conspirator Trends in Cell Biology 2005 15 9 457 459 (Pubitemid 41253464)
34. Shankar D. B., Cheng J. C., Sakamoto K. M., Role of cyclic AMP response element binding protein in human leukemias Cancer 2005 104 9 1819 1824
35. Sakamoto K. M., Fraser J. K., Lee H.-J. J., Lehman E., Gasson J. C., Granulocyte-macrophage colony-stimulating factor and interleukin-3 signaling pathways converge on the CREB-binding site in the human egr-1 promoter Molecular and Cellular Biology 1994 14 9 5975 5985 (Pubitemid 24264426)
36. Gubina E., Luo X., Kwon E., Sakamoto K., Shi Y. F., Mufson R. A., c cytokine receptor-induced stimulation of cAMP response element binding protein phosphorylation requires protein kinase C in myeloid cells: a novel cytokine signal transduction cascade The Journal of Immunology 2001 167 8 4303 4310 (Pubitemid 32954305)
37. Zauli G., Gibellini D., Vitale M. et al., The induction of megakaryocyte differentiation is accompanied by selective Ser133 phosphorylation of the transcription factor CREB in both HEL cell line and primary CD34+ cells Blood 1998 92 2 472 480 (Pubitemid 28323709)
38. Ji L., Mochon E., Arcinas M., Boxer L. M., CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas The Journal of Biological Chemistry 1996 271 37 22687 22691 (Pubitemid 26304712)
39. Arcinas M., Heckman C. A., Mehew J. W., Boxer L. M., Molecular mechanisms of transcriptional control of bcl-2 and c-myc in follicular and transformed lymphoma Cancer Research 2001 61 13 5202 5206 (Pubitemid 32681554)
40. Blobel G. A. et al., CREB-binding protein and p300: molecular integrators of hematopoietic transcription Blood 2000 95 3 745 755
41. Borrow J., Stanton V. P. Jr. et al., Andresen J. M., The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein Nature Genetics 1996 14 1 33 41 (Pubitemid 26301544)
42. Ida K., Kitabayashi I., Taki T. et al., Adenoviral E1A-associated protein p300 is involved in acute myeloid leukemia with t(11;22)(q23;q13) Blood 1997 90 12 4699 4704 (Pubitemid 28007181)
43. Rowley J. D., Reshmi S., Sobulo O. et al., All patients with the t(11; 16)(q23; p13.3) that involves MLL and CBP have treatment-related hematologic disorders Blood 1997 90 2 535 541 (Pubitemid 27299092)
44. Satake N., Ishida Y., Otoh Y. et al., Novel MLL-CBP fusion transcript in therapy-related chronic myelomonocytic leukemia with a t(11;16) (q23;p13) chromosome translocation Genes Chromosomes and Cancer 1997 20 1 60 63 (Pubitemid 27377100)
45. Sobulo O. M., Borrow J., Tomek R. et al., MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3) Proceedings of the National Academy of Sciences of the United States of America 1997 94 16 8732 8737 (Pubitemid 27335108)
46. Taki T., Sako M., Tsuchida M., Hayashi Y., The t(11;16)(q23;p13) translocation in myelodysplastic syndrome fuses the MLL gene to the CBP gene Blood 1997 89 11 3945 3950 (Pubitemid 27220937)
47. Crans-Vargas H. N., Landaw E. M., Bhatia S., Sandusky G., Moore T. B., Sakamoto K. M., Expression of cyclic adenosine monophosphate response-element binding protein in acute leukemia Blood 2002 99 7 2617 2619 (Pubitemid 34525457)
48. Pigazzi M., Ricotti E., Germano G., Faggian D., Arico M., Basso G., cAMP response element binding protein (CREB) overexpression has been described as critical for leukemia progression Haematologica 2007 92 10 1435 1437 (Pubitemid 350144168)
49. Pigazzi M., Manara E., Baron E., Basso G., ICER expression inhibits leukemia phenotype and controls tumor progression Leukemia 2008 22 12 2217 2225
50. Lewis B. P., Burge C. B., Bartel D. P., Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Cell 2005 120 1 15 20
51. Krek A., Grn D., Poy M. N. et al., Combinatorial microRNA target predictions Nature Genetics 2005 37 5 495 500 (Pubitemid 40617277)
52. Bartel D. P., MicroRNAs: genomics, biogenesis, mechanism, and function Cell 2004 116 2 281 297
53. Ruike Y., Ichimura A., Tsuchiya S. et al., Global correlation analysis for micro-RNA and mRNA expression profiles in human cell lines Journal of Human Genetics 2008 53 6 515 523
54. Papagiannakopoulos T., Kosik K. S., MicroRNAs: regulators of oncogenesis and stemness BMC Medicine 2008 6, article 15
55. Calin G. A., Cimmino A., Fabbri M. et al., MiR-15a and miR-16-1 cluster functions in human leukemia Proceedings of the National Academy of Sciences of the United States of America 2008 105 13 5166 5171 (Pubitemid 351738528)
56. Nicoloso M. S., Kipps T. J., Croce C. M., Calin G. A., MicroRNAs in the pathogeny of chronic lymphocytic leukaemia British Journal of Haematology 2007 139 5 709 716 (Pubitemid 350115732)
57. OConnell R. M., Rao D. S., Chaudhuri A. A. et al., Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder Journal of Experimental Medicine 2008 205 3 585 594
58. Fazi F., Racanicchi S., Zardo G. et al., Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein Cancer Cell 2007 12 5 457 466 (Pubitemid 350046404)
59. Pigazzi M., Manara E., Baron E., Basso G., MiR-34b targets cyclic AMP-responsive element binding protein in acute myeloid leukemia Cancer Research 2009 69 6 2471 2478
60. Fabbri M., Croce C. M., Calin G. A., MicroRNAs Cancer Journal 2008 14 1 1 6
61. Rokhlin O. W., Scheinker V. S., Taghiyev A. F., Bumcrot D., Glover R. A., Cohen M. B., MicroRNA-34 mediates AR-dependent p53-induced apoptosis in prostate cancer Cancer Biology and Therapy 2008 7 8 1288 1296
62. He X., He L., Hannon G. J., The guardians little helper: microRNAs in the p53 tumor suppressor network Cancer Research 2007 67 23 11099 11101 (Pubitemid 350248530)
63. Toyota M., Suzuki H., Sasaki Y. et al., Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer Cancer Research 2008 68 11 4123 4132