Discovering a potent small molecule inhibitor for gankyrin using de novo drug design approach

International Journal of Computational Biology and Drug Design

Volumn 4, Issue 4, 2011, Pages 373-386

  Thakur, Prasoon Kumar ^a   Hassan, Md Imtaiyaz ^a  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

Author keywords

Apoptosis; Cyclin dependent kinase 4; HCC; Hepatocellular carcinoma; Oncoprotein; Proteasome endopeptidase complex; Retinoblastoma protein; Ubiquitination

Indexed keywords

ANKYRIN; ANTINEOPLASTIC AGENT; GANKYRIN; LIGAND; N [2 [1 (5 DIMETHYLAMINO 2,3 DIHYDROINDOL 1 YL)VINYLAMINO] 1 (4 HYDROXYPHENYL)ETHYL]ACETAMIDE; ONCOPROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER CELL; CELL CYCLE REGULATION; DRUG BINDING SITE; DRUG DESIGN; DRUG POTENCY; DRUG PROTEIN BINDING; ENERGY; LIVER CELL CARCINOMA; MOLECULAR DOCKING; MOLECULAR INTERACTION; PROTEIN EXPRESSION;

EID: 84857273255     PISSN: 17560756     EISSN: 17560764     Source Type: Journal    
DOI: 10.1504/IJCBDD.2011.044404     Document Type: Article

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