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Volumn 46, Issue 2, 2015, Pages 507-523

Inflammation combined with ischemia produces myelin injury and plaque-like aggregates of myelin, amyloid-β and AβPP in adult rat brain

Author keywords

Alzheimer's disease; amyloid plaques; amyloid ; amyloid protein precursor; hypoxia; lipopolysaccharide; myelin; myelin basic protein

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; GRANZYME B; INTERLEUKIN 1; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MYELIN ASSOCIATED GLYCOPROTEIN; MYELIN BASIC PROTEIN; MYELIN PROTEIN; SPHINGOMYELIN PHOSPHODIESTERASE; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

EID: 84930460163     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-143072     Document Type: Article
Times cited : (35)

References (61)
  • 1
    • 35748959415 scopus 로고    scopus 로고
    • Mixed brain pathologies account for most dementia cases in community-dwelling older persons
    • Schneider JA, Arvanitakis Z, Bang W, Bennett DA (2007) Mixed brain pathologies account for most dementia cases in community-dwelling older persons. Neurology 69, 2197-2204
    • (2007) Neurology , vol.69 , pp. 2197-2204
    • Schneider, J.A.1    Arvanitakis, Z.2    Bang, W.3    Bennett, D.A.4
  • 5
    • 0035833964 scopus 로고    scopus 로고
    • Poststroke dementia: Incidence and relationship to prestroke cognitive decline
    • Henon H, Durieu I, Guerouaou D, Lebert F, Pasquier F, Leys D (2001) Poststroke dementia: Incidence and relationship to prestroke cognitive decline. Neurology 57, 1216-1222
    • (2001) Neurology , vol.57 , pp. 1216-1222
    • Henon, H.1    Durieu, I.2    Guerouaou, D.3    Lebert, F.4    Pasquier, F.5    Leys, D.6
  • 8
    • 0025331137 scopus 로고
    • Relation of leukoaraiosis to lesion type in stroke patients
    • Hijdra A, Verbeeten B Jr, Verhulst JA (1990) Relation of leukoaraiosis to lesion type in stroke patients. Stroke 21, 890-894
    • (1990) Stroke , vol.21 , pp. 890-894
    • Hijdra, A.1    Verbeeten, B.2    Verhulst, J.A.3
  • 10
    • 84899130881 scopus 로고    scopus 로고
    • Epigenetic modifications of chronic hypoxia-mediated neurodegeneration in Alzheimer's disease
    • Liu H, Le W (2014) Epigenetic modifications of chronic hypoxia-mediated neurodegeneration in Alzheimer's disease. Transl Neurodegener 3, 7
    • (2014) Transl Neurodegener , vol.3 , pp. 7
    • Liu, H.1    Le, W.2
  • 12
    • 84888019151 scopus 로고    scopus 로고
    • The pathobiology of vascular dementia
    • Iadecola C (2013) The pathobiology of vascular dementia. Neuron 80, 844-866
    • (2013) Neuron , vol.80 , pp. 844-866
    • Iadecola, C.1
  • 13
    • 0034484584 scopus 로고    scopus 로고
    • Delirium in elderly people without severe predisposing disorders: Etiology and 1-year prognosis after discharge
    • Rahkonen T, Makela H, Paanila S, Halonen P, Sivenius J, Sulkava R (2000) Delirium in elderly people without severe predisposing disorders: Etiology and 1-year prognosis after discharge. Int Psychogeriatr 12, 473-481
    • (2000) Int Psychogeriatr , vol.12 , pp. 473-481
    • Rahkonen, T.1    Makela, H.2    Paanila, S.3    Halonen, P.4    Sivenius, J.5    Sulkava, R.6
  • 14
    • 23044447002 scopus 로고    scopus 로고
    • Association between dementia and infectious disease: Evidence from a case-control study
    • Dunn N, Mullee M, Perry VH, Holmes C (2005) Association between dementia and infectious disease: Evidence from a case-control study. Alzheimer Dis Assoc Disord 19, 91-94
    • (2005) Alzheimer Dis Assoc Disord , vol.19 , pp. 91-94
    • Dunn, N.1    Mullee, M.2    Perry, V.H.3    Holmes, C.4
  • 15
    • 0035680978 scopus 로고    scopus 로고
    • Past exposure to vaccines and subsequent risk of Alzheimer's disease
    • Verreault R, Laurin D, Lindsay J, De Serres G (2001) Past exposure to vaccines and subsequent risk of Alzheimer's disease. CMAJ 165, 1495-1498
    • (2001) CMAJ , vol.165 , pp. 1495-1498
    • Verreault, R.1    Laurin, D.2    Lindsay, J.3    De Serres, G.4
  • 17
    • 79955781842 scopus 로고    scopus 로고
    • The developing oligodendrocyte: Key cellular target in brain injury in the premature infant
    • Volpe JJ, Kinney HC, Jensen FE, Rosenberg PA (2011) The developing oligodendrocyte: Key cellular target in brain injury in the premature infant. Int JDev Neurosci 29, 423-440
    • (2011) Int JDev Neurosci , vol.29 , pp. 423-440
    • Volpe, J.J.1    Kinney, H.C.2    Jensen, F.E.3    Rosenberg, P.A.4
  • 19
    • 33749521100 scopus 로고    scopus 로고
    • Intraneuronal beta-Amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation
    • Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, Berry R, Vassar R (2006) Intraneuronal beta-Amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation. J Neurosci 26, 10129-10140
    • (2006) J Neurosci , vol.26 , pp. 10129-10140
    • Oakley, H.1    Cole, S.L.2    Logan, S.3    Maus, E.4    Shao, P.5    Craft, J.6    Guillozet-Bongaarts, A.7    Ohno, M.8    Disterhoft, J.9    Van Eldik, L.10    Berry, R.11    Vassar, R.12
  • 20
    • 52049112072 scopus 로고    scopus 로고
    • Very brief focal ischemia simulating transient ischemic attacks (TIAs) can injure brain and induce Hsp70 protein
    • Zhan X, Kim C, Sharp FR (2008) Very brief focal ischemia simulating transient ischemic attacks (TIAs) can injure brain and induce Hsp70 protein. Brain Res 1234, 183-197
    • (2008) Brain Res , vol.1234 , pp. 183-197
    • Zhan, X.1    Kim, C.2    Sharp, F.R.3
  • 21
    • 3242674405 scopus 로고    scopus 로고
    • Fluoro-substituted and 13C-labeled styrylbenzene derivatives for detecting brain amyloid plaques
    • Sato K, Higuchi M, Iwata N, Saido TC, Sasamoto K (2004) Fluoro-substituted and 13C-labeled styrylbenzene derivatives for detecting brain amyloid plaques. Eur J Med Chem 39, 573-578
    • (2004) Eur J Med Chem , vol.39 , pp. 573-578
    • Sato, K.1    Higuchi, M.2    Iwata, N.3    Saido, T.C.4    Sasamoto, K.5
  • 22
    • 84896324370 scopus 로고    scopus 로고
    • The role of inflammasome in Alzheimer's disease
    • Liu L, Chan C (2014) The role of inflammasome in Alzheimer's disease. Ageing Res Rev 15C, 6-15
    • (2014) Ageing Res Rev , vol.15 C , pp. 6-15
    • Liu, L.1    Chan, C.2
  • 23
    • 84870255907 scopus 로고    scopus 로고
    • Granzyme B in injury, inflammation, and repair
    • Hiebert PR, Granville DJ (2012) Granzyme B in injury, inflammation, and repair. Trends Mol Med 18, 732-741
    • (2012) Trends Mol Med , vol.18 , pp. 732-741
    • Hiebert, P.R.1    Granville, D.J.2
  • 24
    • 70350366775 scopus 로고    scopus 로고
    • Degradation of amyloid beta protein by purified myelin basic protein
    • Liao MC, Ahmed M, Smith SO, Van Nostrand WE (2009) Degradation of amyloid beta protein by purified myelin basic protein. J Biol Chem 284, 28917-28925
    • (2009) J Biol Chem , vol.284 , pp. 28917-28925
    • Liao, M.C.1    Ahmed, M.2    Smith, S.O.3    Van Nostrand, W.E.4
  • 25
    • 66649118037 scopus 로고    scopus 로고
    • Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro
    • Hoos MD, Ahmed M, Smith SO, Van Nostrand WE (2009) Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro. Biochemistry 48, 4720-4727
    • (2009) Biochemistry , vol.48 , pp. 4720-4727
    • Hoos, M.D.1    Ahmed, M.2    Smith, S.O.3    Van Nostrand, W.E.4
  • 26
    • 81555200043 scopus 로고    scopus 로고
    • Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
    • Zlokovic BV (2011) Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat Rev Neurosci 12, 723-738
    • (2011) Nat Rev Neurosci , vol.12 , pp. 723-738
    • Zlokovic, B.V.1
  • 27
    • 0027291534 scopus 로고
    • Recognition of bacterial endotoxins by receptor-dependent mechanisms
    • Ulevitch RJ (1993) Recognition of bacterial endotoxins by receptor-dependent mechanisms. Adv Immunol 53, 267-289
    • (1993) Adv Immunol , vol.53 , pp. 267-289
    • Ulevitch, R.J.1
  • 28
    • 33751554878 scopus 로고    scopus 로고
    • A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide
    • Zhou H, Lapointe BM, Clark SR, Zbytnuik L, Kubes P (2006) A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide. J Immunol 177, 8103-8110
    • (2006) J Immunol , vol.177 , pp. 8103-8110
    • Zhou, H.1    Lapointe, B.M.2    Clark, S.R.3    Zbytnuik, L.4    Kubes, P.5
  • 29
    • 0031831764 scopus 로고    scopus 로고
    • Gelatinase B modulates selective opening of the blood-brain barrier during inflammation
    • Mun-Bryce S, Rosenberg GA (1998) Gelatinase B modulates selective opening of the blood-brain barrier during inflammation. Am J Physiol 274, R1203-R1211
    • (1998) Am J Physiol , vol.274 , pp. R1203-R1211
    • Mun-Bryce, S.1    Rosenberg, G.A.2
  • 30
    • 21244482466 scopus 로고    scopus 로고
    • Acute lipopolysaccharide-mediated injury in neonatal white matter glia: Role of TNF-Alpha, IL-1beta, and calcium
    • Sherwin C, FernR(2005) Acute lipopolysaccharide-mediated injury in neonatal white matter glia: Role of TNF-Alpha, IL-1beta, and calcium. J Immunol 175, 155-161
    • (2005) J Immunol , vol.175 , pp. 155-161
    • Sherwin, C.1    Fern, R.2
  • 31
    • 0027156798 scopus 로고
    • Hydrolysis of myelin basic protein in myelin membranes by granzymes of large granular lymphocytes
    • Vanguri P, Lee E, Henkart P, Shin ML (1993) Hydrolysis of myelin basic protein in myelin membranes by granzymes of large granular lymphocytes. J Immunol 150, 2431-2439
    • (1993) J Immunol , vol.150 , pp. 2431-2439
    • Vanguri, P.1    Lee, E.2    Henkart, P.3    Shin, M.L.4
  • 32
    • 0034651593 scopus 로고    scopus 로고
    • Extracellular granzyme A, complexed to proteoglycans, is protected against inactivation by protease inhibitors
    • Spaeny-Dekking EH, Kamp AM, Froelich CJ, Hack CE (2000) Extracellular granzyme A, complexed to proteoglycans, is protected against inactivation by protease inhibitors. Blood 95, 1465-1472
    • (2000) Blood , vol.95 , pp. 1465-1472
    • Spaeny-Dekking, E.H.1    Kamp, A.M.2    Froelich, C.J.3    Hack, C.E.4
  • 34
    • 34249732616 scopus 로고    scopus 로고
    • Mechanisms of regulation for interleukin-1beta in neurodegenerative disease
    • Simi A, Lerouet D, Pinteaux E, Brough D (2007) Mechanisms of regulation for interleukin-1beta in neurodegenerative disease. Neuropharmacology 52, 1563-1569
    • (2007) Neuropharmacology , vol.52 , pp. 1563-1569
    • Simi, A.1    Lerouet, D.2    Pinteaux, E.3    Brough, D.4
  • 35
  • 37
    • 84886928516 scopus 로고    scopus 로고
    • Acidosis drives damage-Associated molecular pattern (DAMP)-induced interleukin-1 secretion via a caspase-1-independent pathway
    • Edye ME, Lopez-Castejon G, Allan SM, Brough D (2013) Acidosis drives damage-Associated molecular pattern (DAMP)-induced interleukin-1 secretion via a caspase-1-independent pathway. J Biol Chem 288, 30485-30494
    • (2013) J Biol Chem , vol.288 , pp. 30485-30494
    • Edye, M.E.1    Lopez-Castejon, G.2    Allan, S.M.3    Brough, D.4
  • 38
    • 84920856216 scopus 로고    scopus 로고
    • Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes
    • Shamseddine AA, Airola MV, Hannun YA (2015) Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes. Adv Biol Regul 57C, 24-41
    • (2015) Adv Biol Regul , vol.57 C , pp. 24-41
    • Shamseddine, A.A.1    Airola, M.V.2    Hannun, Y.A.3
  • 45
    • 0031785202 scopus 로고    scopus 로고
    • P75 and TrkA receptor signaling independently regulate amyloid precursor protein mRNA expression, isoform composition, and protein secretion in PC12 cells
    • Rossner S, Ueberham U, Schliebs R, Perez-Polo JR, Bigl V (1998) p75 and TrkA receptor signaling independently regulate amyloid precursor protein mRNA expression, isoform composition, and protein secretion in PC12 cells. J Neurochem 71, 757-766
    • (1998) J Neurochem , vol.71 , pp. 757-766
    • Rossner, S.1    Ueberham, U.2    Schliebs, R.3    Perez-Polo, J.R.4    Bigl, V.5
  • 46
    • 0030805991 scopus 로고    scopus 로고
    • Frequency of stages of Alzheimerrelated lesions in different age categories
    • Braak H, Braak E (1997) Frequency of stages of Alzheimerrelated lesions in different age categories. Neurobiol Aging 18, 351-357
    • (1997) Neurobiol Aging , vol.18 , pp. 351-357
    • Braak, H.1    Braak, E.2
  • 47
    • 0037337293 scopus 로고    scopus 로고
    • White matter structural integrity in healthy aging adults and patients with Alzheimer disease: A magnetic resonance imaging study
    • Bartzokis G, Cummings JL, Sultzer D, Henderson VW, Nuechterlein KH, Mintz J (2003) White matter structural integrity in healthy aging adults and patients with Alzheimer disease: A magnetic resonance imaging study. Arch Neurol 60, 393-398
    • (2003) Arch Neurol , vol.60 , pp. 393-398
    • Bartzokis, G.1    Cummings, J.L.2    Sultzer, D.3    Henderson, V.W.4    Nuechterlein, K.H.5    Mintz, J.6
  • 48
    • 3042662696 scopus 로고    scopus 로고
    • Heterogeneous age-related breakdown of white matter structural integrity: Implications for cortical disconnection" in aging and Alzheimer's disease
    • Bartzokis G, Sultzer D, Lu PH, Nuechterlein KH, Mintz J, Cummings JL (2004) Heterogeneous age-related breakdown of white matter structural integrity: Implications for cortical "disconnection" in aging and Alzheimer's disease. Neurobiol Aging 25, 843-851
    • (2004) Neurobiol Aging , vol.25 , pp. 843-851
    • Bartzokis, G.1    Sultzer, D.2    Lu, P.H.3    Nuechterlein, K.H.4    Mintz, J.5    Cummings, J.L.6
  • 49
    • 79959599177 scopus 로고    scopus 로고
    • Alzheimer's disease as homeostatic responses to age-related myelin breakdown
    • Bartzokis G (2011) Alzheimer's disease as homeostatic responses to age-related myelin breakdown. Neurobiol Aging 32, 1341-1371
    • (2011) Neurobiol Aging , vol.32 , pp. 1341-1371
    • Bartzokis, G.1
  • 50
    • 61449120013 scopus 로고    scopus 로고
    • Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology
    • Desai MK, Sudol KL, Janelsins MC, Mastrangelo MA, Frazer ME, Bowers WJ (2009) Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology. Glia 57, 54-65
    • (2009) Glia , vol.57 , pp. 54-65
    • Desai, M.K.1    Sudol, K.L.2    Janelsins, M.C.3    Ma, M.4    Frazer, M.E.5    Bowers, W.J.6
  • 51
    • 0034503034 scopus 로고    scopus 로고
    • Vulnerability of select neuronal types to Alzheimer's disease
    • Braak H, Del Tredici K, Schultz C, Braak E (2000) Vulnerability of select neuronal types to Alzheimer's disease. Ann N Y Acad Sci 924, 53-61
    • (2000) Ann N y Acad Sci , vol.924 , pp. 53-61
    • Braak, H.1    Del Tredici, K.2    Schultz, C.3    Braak, E.4
  • 52
    • 0024207078 scopus 로고
    • White matter changes in dementia of Alzheimer's type. Biochemical and neuropathological correlates
    • Pt6
    • Englund E, Brun A, Alling C (1988) White matter changes in dementia of Alzheimer's type. Biochemical and neuropathological correlates. Brain 111(Pt 6), 1425-1439
    • (1988) Brain , vol.111 , pp. 1425-1439
    • Englund, E.1    Brun, A.2    Alling, C.3
  • 55
    • 84856353669 scopus 로고    scopus 로고
    • High-molecular weight Abeta oligomers and protofibrils are the predominant Abeta species in the native soluble protein fraction of the AD brain
    • Upadhaya AR, Lungrin I, Yamaguchi H, Fandrich M, Thal DR (2012) High-molecular weight Abeta oligomers and protofibrils are the predominant Abeta species in the native soluble protein fraction of the AD brain. J Cell Mol Med 16, 287-295
    • (2012) J Cell Mol Med , vol.16 , pp. 287-295
    • Upadhaya, A.R.1    Lungrin, I.2    Yamaguchi, H.3    Fandrich, M.4    Thal, D.R.5
  • 57
    • 0042835437 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice
    • Sheng JG, Bora SH, Xu G, Borchelt DR, Price DL, Koliatsos VE (2003) Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice. Neurobiol Dis 14, 133-145
    • (2003) Neurobiol Dis , vol.14 , pp. 133-145
    • Sheng, J.G.1    Bora, S.H.2    Xu, G.3    Borchelt, D.R.4    Price, D.L.5    Koliatsos, V.E.6
  • 58
    • 63249094657 scopus 로고    scopus 로고
    • Lipopolysaccharide alters the bloodbrain barrier transport of amyloid beta protein: A mechanism for inflammation in the progression of Alzheimer's disease
    • Jaeger LB, Dohgu S, Sultana R, Lynch JL, Owen JB, Erickson MA, Shah GN, Price TO, Fleegal-Demotta MA, Butterfield DA, Banks WA (2009) Lipopolysaccharide alters the bloodbrain barrier transport of amyloid beta protein: A mechanism for inflammation in the progression of Alzheimer's disease. Brain Behav Immun 23, 507-517
    • (2009) Brain Behav Immun , vol.23 , pp. 507-517
    • Jaeger, L.B.1    Dohgu, S.2    Sultana, R.3    Lynch, J.L.4    Owen, J.B.5    Ma, E.6    Shah, G.N.7    Price, T.O.8    Ma, F.9    Butterfield, D.A.10    Banks, W.A.11
  • 59
    • 84863005570 scopus 로고    scopus 로고
    • Lipopolysaccharide impairs amyloid beta efflux from brain: Altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood-brain barrier
    • Erickson MA, Hartvigson PE, Morofuji Y, Owen JB, Butterfield DA, Banks WA (2012) Lipopolysaccharide impairs amyloid beta efflux from brain: Altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood-brain barrier. J Neuroinflammation 9, 150
    • (2012) J Neuroinflammation , vol.9 , pp. 150
    • Ma, E.1    Hartvigson, P.E.2    Morofuji, Y.3    Owen, J.B.4    Butterfield, D.A.5    Banks, W.A.6
  • 60
    • 81955164209 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate attenuates brain Abeta increase and improves long-term neurological outcome in rats after transient focal brain ischemia
    • Li J, Sheng W, Feng C, Zuo Z (2012) Pyrrolidine dithiocarbamate attenuates brain Abeta increase and improves long-term neurological outcome in rats after transient focal brain ischemia. Neurobiol Dis 45, 564-572
    • (2012) Neurobiol Dis , vol.45 , pp. 564-572
    • Li, J.1    Sheng, W.2    Feng, C.3    Zuo, Z.4


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