-
1
-
-
0035487313
-
Cytokines and acute neurodegeneration
-
Allan S.M., and Rothwell N.J. Cytokines and acute neurodegeneration. Nat. Rev. Neurosci. 2 (2001) 734-744
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 734-744
-
-
Allan, S.M.1
Rothwell, N.J.2
-
2
-
-
0032923377
-
The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles
-
Andrei C., Dazzi C., Lotti L., Torrisi M.R., Chimini G., and Rubartelli A. The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles. Mol. Biol. Cell 10 (1999) 1463-1475
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 1463-1475
-
-
Andrei, C.1
Dazzi, C.2
Lotti, L.3
Torrisi, M.R.4
Chimini, G.5
Rubartelli, A.6
-
3
-
-
3042800587
-
Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: implications for inflammatory processes
-
Andrei C., Margiocco P., Poggi A., Lotti L.V., Torrisi M.R., and Rubartelli A. Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: implications for inflammatory processes. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 9745-9750
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 9745-9750
-
-
Andrei, C.1
Margiocco, P.2
Poggi, A.3
Lotti, L.V.4
Torrisi, M.R.5
Rubartelli, A.6
-
4
-
-
0035124607
-
Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia
-
Barone F.C., Irving E.A., Ray A.M., Lee J.C., Kassis S., Kumar S., Badger A.M., Legos J.J., Erhardt J.A., Ohlstein E.H., Hunter A.J., Harrison D.C., Philpott K., Smith B.R., Adams J.L., and Parsons A.A. Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia. Med. Res. Rev. 21 (2001) 129-145
-
(2001)
Med. Res. Rev.
, vol.21
, pp. 129-145
-
-
Barone, F.C.1
Irving, E.A.2
Ray, A.M.3
Lee, J.C.4
Kassis, S.5
Kumar, S.6
Badger, A.M.7
Legos, J.J.8
Erhardt, J.A.9
Ohlstein, E.H.10
Hunter, A.J.11
Harrison, D.C.12
Philpott, K.13
Smith, B.R.14
Adams, J.L.15
Parsons, A.A.16
-
5
-
-
18944380607
-
Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia
-
Bianco F., Pravettoni E., Colombo A., Schenk U., Moller T., Matteoli M., and Verderio C. Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia. J. Immunol. 174 (2005) 7268-7277
-
(2005)
J. Immunol.
, vol.174
, pp. 7268-7277
-
-
Bianco, F.1
Pravettoni, E.2
Colombo, A.3
Schenk, U.4
Moller, T.5
Matteoli, M.6
Verderio, C.7
-
6
-
-
0023947763
-
Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor
-
Black R.A., Kronheim S.R., Cantrell M., Deeley M.C., March C.J., Prickett K.S., Wignall J., Conlon P.J., Cosman D., and Hopp T.P. Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor. J. Biol. Chem. 263 (1988) 9437-9442
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 9437-9442
-
-
Black, R.A.1
Kronheim, S.R.2
Cantrell, M.3
Deeley, M.C.4
March, C.J.5
Prickett, K.S.6
Wignall, J.7
Conlon, P.J.8
Cosman, D.9
Hopp, T.P.10
-
7
-
-
0035413361
-
Role of IL-1alpha and IL-1beta in ischemic brain damage
-
Boutin H., LeFeuvre R.A., Horai R., Asano M., Iwakura Y., and Rothwell N.J. Role of IL-1alpha and IL-1beta in ischemic brain damage. J. Neurosci. 21 (2001) 5528-5534
-
(2001)
J. Neurosci.
, vol.21
, pp. 5528-5534
-
-
Boutin, H.1
LeFeuvre, R.A.2
Horai, R.3
Asano, M.4
Iwakura, Y.5
Rothwell, N.J.6
-
8
-
-
2642559875
-
Targeting IL-1 in inflammatory disease: new opportunities for therapeutic intervention
-
Braddock M., and Quinn A. Targeting IL-1 in inflammatory disease: new opportunities for therapeutic intervention. Nat. Rev. Drug Discov. 3 (2004) 330-339
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 330-339
-
-
Braddock, M.1
Quinn, A.2
-
9
-
-
0035303568
-
The safety and efficacy of interleukin-1 receptor antagonist in the treatment of rheumatoid arthritis
-
Bresnihan B. The safety and efficacy of interleukin-1 receptor antagonist in the treatment of rheumatoid arthritis. Semin. Arthritis Rheum. 30 (2001) 17-20
-
(2001)
Semin. Arthritis Rheum.
, vol.30
, pp. 17-20
-
-
Bresnihan, B.1
-
10
-
-
34047179487
-
Caspase-1-dependent processing of pro-interleukin-1beta is cytosolic and precedes cell death
-
Brough D., and Rothwell N.J. Caspase-1-dependent processing of pro-interleukin-1beta is cytosolic and precedes cell death. J. Cell Sci. 120 (2007) 772-781
-
(2007)
J. Cell Sci.
, vol.120
, pp. 772-781
-
-
Brough, D.1
Rothwell, N.J.2
-
11
-
-
0036200917
-
Purinergic (P2X7) receptor activation of microglia induces cell death via an interleukin-1-independent mechanism
-
Brough D., Le Feuvre R.A., Iwakura Y., and Rothwell N.J. Purinergic (P2X7) receptor activation of microglia induces cell death via an interleukin-1-independent mechanism. Mol. Cell Neurosci. 19 (2002) 272-280
-
(2002)
Mol. Cell Neurosci.
, vol.19
, pp. 272-280
-
-
Brough, D.1
Le Feuvre, R.A.2
Iwakura, Y.3
Rothwell, N.J.4
-
12
-
-
0037443542
-
Ca2+ stores and Ca2+ entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages
-
Brough D., Le Feuvre R.A., Wheeler R.D., Solovyova N., Hilfiker S., Rothwell N.J., and Verkhratsky A. Ca2+ stores and Ca2+ entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages. J. Immunol. 170 (2003) 3029-3036
-
(2003)
J. Immunol.
, vol.170
, pp. 3029-3036
-
-
Brough, D.1
Le Feuvre, R.A.2
Wheeler, R.D.3
Solovyova, N.4
Hilfiker, S.5
Rothwell, N.J.6
Verkhratsky, A.7
-
13
-
-
0037092429
-
ADP and AMP induce interleukin-1beta release from microglial cells through activation of ATP-primed P2X7 receptor channels
-
Chakfe Y., Seguin R., Antel J.P., Morissette C., Malo D., Henderson D., and Seguela P. ADP and AMP induce interleukin-1beta release from microglial cells through activation of ATP-primed P2X7 receptor channels. J. Neurosci. 22 (2002) 3061-3069
-
(2002)
J. Neurosci.
, vol.22
, pp. 3061-3069
-
-
Chakfe, Y.1
Seguin, R.2
Antel, J.P.3
Morissette, C.4
Malo, D.5
Henderson, D.6
Seguela, P.7
-
14
-
-
0036286317
-
Rat microglial cells secrete predominantly the precursor of interleukin-1beta in response to lipopolysaccharide
-
Chauvet N., Palin K., Verrier D., Poole S., Dantzer R., and Lestage J. Rat microglial cells secrete predominantly the precursor of interleukin-1beta in response to lipopolysaccharide. Eur. J. Neurosci. 14 (2001) 609-617
-
(2001)
Eur. J. Neurosci.
, vol.14
, pp. 609-617
-
-
Chauvet, N.1
Palin, K.2
Verrier, D.3
Poole, S.4
Dantzer, R.5
Lestage, J.6
-
15
-
-
0032989434
-
Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3
-
Coeshott C., Ohnemus C., Pilyavskaya A., Ross S., Wieczorek M., Kroona H., Leimer A.H., and Cheronis J. Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 6261-6266
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 6261-6266
-
-
Coeshott, C.1
Ohnemus, C.2
Pilyavskaya, A.3
Ross, S.4
Wieczorek, M.5
Kroona, H.6
Leimer, A.H.7
Cheronis, J.8
-
16
-
-
29844458758
-
Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion
-
Collino M., Aragno M., Mastrocola R., Gallicchio M., Rosa A.C., Dianzani C., Danni O., Thiemermann C., and Fantozzi R. Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion. Eur. J. Pharmacol. 530 (2006) 70-80
-
(2006)
Eur. J. Pharmacol.
, vol.530
, pp. 70-80
-
-
Collino, M.1
Aragno, M.2
Mastrocola, R.3
Gallicchio, M.4
Rosa, A.C.5
Dianzani, C.6
Danni, O.7
Thiemermann, C.8
Fantozzi, R.9
-
17
-
-
1842581655
-
A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release
-
Elssner A., Duncan M., Gavrilin M., and Wewers M.D. A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release. J. Immunol. 172 (2004) 4987-4994
-
(2004)
J. Immunol.
, vol.172
, pp. 4987-4994
-
-
Elssner, A.1
Duncan, M.2
Gavrilin, M.3
Wewers, M.D.4
-
18
-
-
25444517949
-
A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients
-
Emsley H.C., Smith C.J., Georgiou R.F., Vail A., Hopkins S.J., Rothwell N.J., and Tyrrell P.J. A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients. J. Neurol. Neurosurg. Psychiatry 76 (2005) 1366-1372
-
(2005)
J. Neurol. Neurosurg. Psychiatry
, vol.76
, pp. 1366-1372
-
-
Emsley, H.C.1
Smith, C.J.2
Georgiou, R.F.3
Vail, A.4
Hopkins, S.J.5
Rothwell, N.J.6
Tyrrell, P.J.7
-
19
-
-
33646071538
-
The astroglial-derived S100beta protein stimulates the expression of nitric oxide synthase in rodent macrophages through p38 MAP kinase activation
-
Esposito G., De F.D., Cirillo C., Sarnelli G., Cuomo R., and Iuvone T. The astroglial-derived S100beta protein stimulates the expression of nitric oxide synthase in rodent macrophages through p38 MAP kinase activation. Life Sci. 78 (2006) 2707-2715
-
(2006)
Life Sci.
, vol.78
, pp. 2707-2715
-
-
Esposito, G.1
De, F.D.2
Cirillo, C.3
Sarnelli, G.4
Cuomo, R.5
Iuvone, T.6
-
20
-
-
0031568401
-
Response to local inflammation of IL-1 beta-converting enzyme-deficient mice
-
Fantuzzi G., Ku G., Harding M.W., Livingston D.J., Sipe J.D., Kuida K., Flavell R.A., and Dinarello C.A. Response to local inflammation of IL-1 beta-converting enzyme-deficient mice. J. Immunol. 158 (1997) 1818-1824
-
(1997)
J. Immunol.
, vol.158
, pp. 1818-1824
-
-
Fantuzzi, G.1
Ku, G.2
Harding, M.W.3
Livingston, D.J.4
Sipe, J.D.5
Kuida, K.6
Flavell, R.A.7
Dinarello, C.A.8
-
21
-
-
0031201476
-
Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages
-
Ferrari D., Chiozzi P., Falzoni S., Dal S.M., Melchiorri L., Baricordi O.R., and Di V.F. Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages. J. Immunol. 159 (1997) 1451-1458
-
(1997)
J. Immunol.
, vol.159
, pp. 1451-1458
-
-
Ferrari, D.1
Chiozzi, P.2
Falzoni, S.3
Dal, S.M.4
Melchiorri, L.5
Baricordi, O.R.6
Di, V.F.7
-
22
-
-
0031054641
-
Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin
-
Ferrari D., Chiozzi P., Falzoni S., Hanau S., and Di V.F. Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin. J. Exp. Med. 185 (1997) 579-582
-
(1997)
J. Exp. Med.
, vol.185
, pp. 579-582
-
-
Ferrari, D.1
Chiozzi, P.2
Falzoni, S.3
Hanau, S.4
Di, V.F.5
-
23
-
-
0036968944
-
Beta-amyloid-induced inflammation and cholinergic hypofunction in the rat brain in vivo: involvement of the p38MAPK pathway
-
Giovannini M.G., Scali C., Prosperi C., Bellucci A., Vannucchi M.G., Rosi S., Pepeu G., and Casamenti F. Beta-amyloid-induced inflammation and cholinergic hypofunction in the rat brain in vivo: involvement of the p38MAPK pathway. Neurobiol. Dis. 11 (2002) 257-274
-
(2002)
Neurobiol. Dis.
, vol.11
, pp. 257-274
-
-
Giovannini, M.G.1
Scali, C.2
Prosperi, C.3
Bellucci, A.4
Vannucchi, M.G.5
Rosi, S.6
Pepeu, G.7
Casamenti, F.8
-
24
-
-
0032781524
-
Pharmacological characterization of ATP- and LPS-induced IL-1beta release in human monocytes
-
Grahames C.B., Michel A.D., Chessell I.P., and Humphrey P.P. Pharmacological characterization of ATP- and LPS-induced IL-1beta release in human monocytes. Br. J. Pharmacol. 127 (1999) 1915-1921
-
(1999)
Br. J. Pharmacol.
, vol.127
, pp. 1915-1921
-
-
Grahames, C.B.1
Michel, A.D.2
Chessell, I.P.3
Humphrey, P.P.4
-
25
-
-
0028909570
-
ATP induces the release of IL-1 from LPS-primed cells in vivo
-
Griffiths R.J., Stam E.J., Downs J.T., and Otterness I.G. ATP induces the release of IL-1 from LPS-primed cells in vivo. J. Immunol. 154 (1995) 2821-2828
-
(1995)
J. Immunol.
, vol.154
, pp. 2821-2828
-
-
Griffiths, R.J.1
Stam, E.J.2
Downs, J.T.3
Otterness, I.G.4
-
26
-
-
0042242912
-
Essential role for Ca2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells
-
Gudipaty L., Munetz J., Verhoef P.A., and Dubyak G.R. Essential role for Ca2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells. Am. J. Physiol. Cell Physiol. 285 (2003) C286-C299
-
(2003)
Am. J. Physiol. Cell Physiol.
, vol.285
-
-
Gudipaty, L.1
Munetz, J.2
Verhoef, P.A.3
Dubyak, G.R.4
-
27
-
-
27144453624
-
Peptide-based approaches to treat asthma, arthritis, other autoimmune diseases and pathologies of the central nervous system
-
Hauff K., Zamzow C., Law W.J., De M.J., Kennedy K., and Los M. Peptide-based approaches to treat asthma, arthritis, other autoimmune diseases and pathologies of the central nervous system. Arch. Immunol. Ther. Exp. (Warsz.) 53 (2005) 308-320
-
(2005)
Arch. Immunol. Ther. Exp. (Warsz.)
, vol.53
, pp. 308-320
-
-
Hauff, K.1
Zamzow, C.2
Law, W.J.3
De, M.J.4
Kennedy, K.5
Los, M.6
-
28
-
-
3142713223
-
Inhibition of endotoxin response by synthetic TLR4 antagonists
-
Hawkins L.D., Christ W.J., and Rossignol D.P. Inhibition of endotoxin response by synthetic TLR4 antagonists. Curr. Top. Med. Chem. 4 (2004) 1147-1171
-
(2004)
Curr. Top. Med. Chem.
, vol.4
, pp. 1147-1171
-
-
Hawkins, L.D.1
Christ, W.J.2
Rossignol, D.P.3
-
29
-
-
0025996804
-
Release of IL-1 from mononuclear phagocytes
-
Hogquist K.A., Unanue E.R., and Chaplin D.D. Release of IL-1 from mononuclear phagocytes. J. Immunol. 147 (1991) 2181-2186
-
(1991)
J. Immunol.
, vol.147
, pp. 2181-2186
-
-
Hogquist, K.A.1
Unanue, E.R.2
Chaplin, D.D.3
-
30
-
-
0034787855
-
Cytokine production inhibitors produced by a fungus, Oidiodendron griseum
-
Ichikawa K., Hirai H., Ishiguro M., Kambara T., Kato Y., Kim Y.J., Kojima Y., Matsunaga Y., Nishida H., Shiomi Y., Yoshikawa N., Huang L.H., and Kojima N. Cytokine production inhibitors produced by a fungus, Oidiodendron griseum. J. Antibiot. (Tokyo) 54 (2001) 697-702
-
(2001)
J. Antibiot. (Tokyo)
, vol.54
, pp. 697-702
-
-
Ichikawa, K.1
Hirai, H.2
Ishiguro, M.3
Kambara, T.4
Kato, Y.5
Kim, Y.J.6
Kojima, Y.7
Matsunaga, Y.8
Nishida, H.9
Shiomi, Y.10
Yoshikawa, N.11
Huang, L.H.12
Kojima, N.13
-
31
-
-
0034797704
-
Novel cytokine production inhibitors produced by a basidiomycete, Marasmiellus sp
-
Ichikawa K., Hirai H., Ishiguro M., Kambara T., Kato Y., Kim Y.J., Kojima Y., Matsunaga Y., Nishida H., Shiomi Y., Yoshikawa N., and Kojima N. Novel cytokine production inhibitors produced by a basidiomycete, Marasmiellus sp. J. Antibiot. (Tokyo) 54 (2001) 703-709
-
(2001)
J. Antibiot. (Tokyo)
, vol.54
, pp. 703-709
-
-
Ichikawa, K.1
Hirai, H.2
Ishiguro, M.3
Kambara, T.4
Kato, Y.5
Kim, Y.J.6
Kojima, Y.7
Matsunaga, Y.8
Nishida, H.9
Shiomi, Y.10
Yoshikawa, N.11
Kojima, N.12
-
32
-
-
0028988261
-
Granzyme A is an interleukin 1 beta-converting enzyme
-
Irmler M., Hertig S., MacDonald H.R., Sadoul R., Becherer J.D., Proudfoot A., Solari R., and Tschopp J. Granzyme A is an interleukin 1 beta-converting enzyme. J. Exp. Med. 181 (1995) 1917-1922
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1917-1922
-
-
Irmler, M.1
Hertig, S.2
MacDonald, H.R.3
Sadoul, R.4
Becherer, J.D.5
Proudfoot, A.6
Solari, R.7
Tschopp, J.8
-
33
-
-
0034646936
-
Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat. Brain Res
-
Irving E.A., Barone F.C., Reith A.D., Hadingham S.J., and Parsons A.A. Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat. Brain Res. Mol. Brain Res. 77 (2000) 65-75
-
(2000)
Mol. Brain Res.
, vol.77
, pp. 65-75
-
-
Irving, E.A.1
Barone, F.C.2
Reith, A.D.3
Hadingham, S.J.4
Parsons, A.A.5
-
34
-
-
33646516647
-
Gangliosides trigger inflammatory responses via TLR4 in brain glia
-
Jou I., Lee J.H., Park S.Y., Yoon H.J., Joe E.H., and Park E.J. Gangliosides trigger inflammatory responses via TLR4 in brain glia. Am. J. Pathol. 168 (2006) 1619-1630
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 1619-1630
-
-
Jou, I.1
Lee, J.H.2
Park, S.Y.3
Yoon, H.J.4
Joe, E.H.5
Park, E.J.6
-
35
-
-
0036551332
-
Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins
-
Kakimura J., Kitamura Y., Takata K., Umeki M., Suzuki S., Shibagaki K., Taniguchi T., Nomura Y., Gebicke-Haerter P.J., Smith M.A., Perry G., and Shimohama S. Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins. FASEB J. 16 (2002) 601-603
-
(2002)
FASEB J.
, vol.16
, pp. 601-603
-
-
Kakimura, J.1
Kitamura, Y.2
Takata, K.3
Umeki, M.4
Suzuki, S.5
Shibagaki, K.6
Taniguchi, T.7
Nomura, Y.8
Gebicke-Haerter, P.J.9
Smith, M.A.10
Perry, G.11
Shimohama, S.12
-
36
-
-
0031065115
-
The 3′ untranslated region of IL-1beta regulates protein production
-
Kern J.A., Warnock L.J., and McCafferty J.D. The 3′ untranslated region of IL-1beta regulates protein production. J. Immunol. 158 (1997) 1187-1193
-
(1997)
J. Immunol.
, vol.158
, pp. 1187-1193
-
-
Kern, J.A.1
Warnock, L.J.2
McCafferty, J.D.3
-
37
-
-
0038124263
-
Hypoxic induction of caspase-11/caspase-1/interleukin-1beta in brain microglia
-
Kim N.G., Lee H., Son E., Kwon O.Y., Park J.Y., Park J.H., Cho G.J., Choi W.S., and Suk K. Hypoxic induction of caspase-11/caspase-1/interleukin-1beta in brain microglia. Brain Res. Mol. Brain Res. 114 (2003) 107-114
-
(2003)
Brain Res. Mol. Brain Res.
, vol.114
, pp. 107-114
-
-
Kim, N.G.1
Lee, H.2
Son, E.3
Kwon, O.Y.4
Park, J.Y.5
Park, J.H.6
Cho, G.J.7
Choi, W.S.8
Suk, K.9
-
38
-
-
1542298238
-
Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1 beta production
-
Kim S.H., Smith C.J., and Van Eldik L.J. Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1 beta production. Neurobiol. Aging 25 (2004) 431-439
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 431-439
-
-
Kim, S.H.1
Smith, C.J.2
Van Eldik, L.J.3
-
39
-
-
0033145354
-
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
-
Kotlyarov A., Neininger A., Schubert C., Eckert R., Birchmeier C., Volk H.D., and Gaestel M. MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat. Cell Biol. 1 (1999) 94-97
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 94-97
-
-
Kotlyarov, A.1
Neininger, A.2
Schubert, C.3
Eckert, R.4
Birchmeier, C.5
Volk, H.D.6
Gaestel, M.7
-
40
-
-
0037930829
-
Glutathione S-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1beta posttranslational processing
-
Laliberte R.E., Perregaux D.G., Hoth L.R., Rosner P.J., Jordan C.K., Peese K.M., Eggler J.F., Dombroski M.A., Geoghegan K.F., and Gabel C.A. Glutathione S-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1beta posttranslational processing. J. Biol. Chem. 278 (2003) 16567-16578
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16567-16578
-
-
Laliberte, R.E.1
Perregaux, D.G.2
Hoth, L.R.3
Rosner, P.J.4
Jordan, C.K.5
Peese, K.M.6
Eggler, J.F.7
Dombroski, M.A.8
Geoghegan, K.F.9
Gabel, C.A.10
-
41
-
-
0031595870
-
Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat
-
Lawrence C.B., Allan S.M., and Rothwell N.J. Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat. Eur. J. Neurosci. 10 (1998) 1188-1195
-
(1998)
Eur. J. Neurosci.
, vol.10
, pp. 1188-1195
-
-
Lawrence, C.B.1
Allan, S.M.2
Rothwell, N.J.3
-
42
-
-
0036479134
-
Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production
-
Le Feuvre R.A., Brough D., Iwakura Y., Takeda K., and Rothwell N.J. Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production. J. Biol. Chem. 277 (2002) 3210-3218
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3210-3218
-
-
Le Feuvre, R.A.1
Brough, D.2
Iwakura, Y.3
Takeda, K.4
Rothwell, N.J.5
-
43
-
-
0037025282
-
Extracellular ATP and P2X7 receptors in neurodegeneration
-
Le Feuvre R.A., Brough D., and Rothwell N. Extracellular ATP and P2X7 receptors in neurodegeneration. Eur. J. Pharmacol. 447 (2002) 261-269
-
(2002)
Eur. J. Pharmacol.
, vol.447
, pp. 261-269
-
-
Le Feuvre, R.A.1
Brough, D.2
Rothwell, N.3
-
45
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee J.C., Laydon J.T., McDonnell P.C., Gallagher T.F., Kumar S., Green D., McNulty D., Blumenthal M.J., Heys J.R., Landvatter S.W., et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372 (1994) 739-746
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
46
-
-
33646077663
-
Evidence that caspase-1 is a negative regulator of AMPA receptor-mediated long-term potentiation at hippocampal synapses
-
Lu C., Wang Y., Furukawa K., Fu W., Ouyang X., and Mattson M.P. Evidence that caspase-1 is a negative regulator of AMPA receptor-mediated long-term potentiation at hippocampal synapses. J. Neurochem. 97 (2006) 1104-1110
-
(2006)
J. Neurochem.
, vol.97
, pp. 1104-1110
-
-
Lu, C.1
Wang, Y.2
Furukawa, K.3
Fu, W.4
Ouyang, X.5
Mattson, M.P.6
-
47
-
-
30444459031
-
The role of inflammation in CNS injury and disease
-
Lucas S.M., Rothwell N.J., and Gibson R.M. The role of inflammation in CNS injury and disease. Br. J. Pharmacol. 147 Suppl. 1 (2006) S232-S240
-
(2006)
Br. J. Pharmacol.
, vol.147
, Issue.SUPPL. 1
-
-
Lucas, S.M.1
Rothwell, N.J.2
Gibson, R.M.3
-
48
-
-
0033933546
-
Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats
-
Mabuchi T., Kitagawa K., Ohtsuki T., Kuwabara K., Yagita Y., Yanagihara T., Hori M., and Matsumoto M. Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats. Stroke 31 (2000) 1735-1743
-
(2000)
Stroke
, vol.31
, pp. 1735-1743
-
-
Mabuchi, T.1
Kitagawa, K.2
Ohtsuki, T.3
Kuwabara, K.4
Yagita, Y.5
Yanagihara, T.6
Hori, M.7
Matsumoto, M.8
-
49
-
-
0035655395
-
Rapid secretion of interleukin-1beta by microvesicle shedding
-
MacKenzie A., Wilson H.L., Kiss-Toth E., Dower S.K., North R.A., and Surprenant A. Rapid secretion of interleukin-1beta by microvesicle shedding. Immunity 15 (2001) 825-835
-
(2001)
Immunity
, vol.15
, pp. 825-835
-
-
MacKenzie, A.1
Wilson, H.L.2
Kiss-Toth, E.3
Dower, S.K.4
North, R.A.5
Surprenant, A.6
-
50
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S., Weiss D.S., Newton K., McBride J., O'Rourke K., Roose-Girma M., Lee W.P., Weinrauch Y., Monack D.M., and Dixit V.M. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440 (2006) 228-232
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
51
-
-
0036671894
-
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F., Burns K., and Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol. Cell 10 (2002) 417-426
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
52
-
-
33750601018
-
Upregulated expression of purinergic P2X(7) receptor in Alzheimer disease and amyloid-beta peptide-treated microglia and in peptide-injected rat hippocampus
-
McLarnon J.G., Ryu J.K., Walker D.G., and Choi H.B. Upregulated expression of purinergic P2X(7) receptor in Alzheimer disease and amyloid-beta peptide-treated microglia and in peptide-injected rat hippocampus. J. Neuropathol. Exp. Neurol. 65 (2006) 1090-1097
-
(2006)
J. Neuropathol. Exp. Neurol.
, vol.65
, pp. 1090-1097
-
-
McLarnon, J.G.1
Ryu, J.K.2
Walker, D.G.3
Choi, H.B.4
-
53
-
-
24144447012
-
ATP extracellular concentrations are increased in the rat striatum during in vivo ischemia
-
Melani A., Turchi D., Vannucchi M.G., Cipriani S., Gianfriddo M., and Pedata F. ATP extracellular concentrations are increased in the rat striatum during in vivo ischemia. Neurochem. Int. 47 (2005) 442-448
-
(2005)
Neurochem. Int.
, vol.47
, pp. 442-448
-
-
Melani, A.1
Turchi, D.2
Vannucchi, M.G.3
Cipriani, S.4
Gianfriddo, M.5
Pedata, F.6
-
54
-
-
33646785516
-
P2X7 receptor modulation on microglial cells and reduction of brain infarct caused by middle cerebral artery occlusion in rat
-
Melani A., Amadio S., Gianfriddo M., Vannucchi M.G., Volonte C., Bernardi G., Pedata F., and Sancesario G. P2X7 receptor modulation on microglial cells and reduction of brain infarct caused by middle cerebral artery occlusion in rat. J. Cereb. Blood Flow Metab. 26 (2006) 974-982
-
(2006)
J. Cereb. Blood Flow Metab.
, vol.26
, pp. 974-982
-
-
Melani, A.1
Amadio, S.2
Gianfriddo, M.3
Vannucchi, M.G.4
Volonte, C.5
Bernardi, G.6
Pedata, F.7
Sancesario, G.8
-
56
-
-
33747191203
-
The inflammasome: first line of the immune response to cell stress
-
Ogura Y., Sutterwala F.S., and Flavell R.A. The inflammasome: first line of the immune response to cell stress. Cell 126 (2006) 659-662
-
(2006)
Cell
, vol.126
, pp. 659-662
-
-
Ogura, Y.1
Sutterwala, F.S.2
Flavell, R.A.3
-
57
-
-
0035971217
-
The extra domain A of fibronectin activates Toll-like receptor 4
-
Okamura Y., Watari M., Jerud E.S., Young D.W., Ishizaka S.T., Rose J., Chow J.C., and Strauss III J.F. The extra domain A of fibronectin activates Toll-like receptor 4. J. Biol. Chem. 276 (2001) 10229-10233
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10229-10233
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
Young, D.W.4
Ishizaka, S.T.5
Rose, J.6
Chow, J.C.7
Strauss III, J.F.8
-
58
-
-
1242336786
-
Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice
-
Oyama J., Blais Jr. C., Liu X., Pu M., Kobzik L., Kelly R.A., and Bourcier T. Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice. Circulation 109 (2004) 784-789
-
(2004)
Circulation
, vol.109
, pp. 784-789
-
-
Oyama, J.1
Blais Jr., C.2
Liu, X.3
Pu, M.4
Kobzik, L.5
Kelly, R.A.6
Bourcier, T.7
-
59
-
-
0038143359
-
P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease
-
Parvathenani L.K., Tertyshnikova S., Greco C.R., Roberts S.B., Robertson B., and Posmantur R. P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease. J. Biol. Chem. 278 (2003) 13309-13317
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13309-13317
-
-
Parvathenani, L.K.1
Tertyshnikova, S.2
Greco, C.R.3
Roberts, S.B.4
Robertson, B.5
Posmantur, R.6
-
60
-
-
0033557187
-
Excitotoxic brain damage in the rat induces interleukin-1beta protein in microglia and astrocytes: correlation with the progression of cell death
-
Pearson V.L., Rothwell N.J., and Toulmond S. Excitotoxic brain damage in the rat induces interleukin-1beta protein in microglia and astrocytes: correlation with the progression of cell death. Glia 25 (1999) 311-323
-
(1999)
Glia
, vol.25
, pp. 311-323
-
-
Pearson, V.L.1
Rothwell, N.J.2
Toulmond, S.3
-
61
-
-
33750473352
-
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor
-
Pelegrin P., and Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J. 25 (2006) 5071-5082
-
(2006)
EMBO J.
, vol.25
, pp. 5071-5082
-
-
Pelegrin, P.1
Surprenant, A.2
-
62
-
-
34047270416
-
Pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1beta release through a dye uptake-independent pathway
-
Pelegrin P., and Surprenant A. Pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1beta release through a dye uptake-independent pathway. J. Biol. Chem. 282 (2007) 2386-2394
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 2386-2394
-
-
Pelegrin, P.1
Surprenant, A.2
-
63
-
-
0028175838
-
Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
-
Perregaux D., and Gabel C.A. Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J. Biol. Chem. 269 (1994) 15195-15203
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15195-15203
-
-
Perregaux, D.1
Gabel, C.A.2
-
64
-
-
0032429611
-
Human monocyte stimulus-coupled IL-1beta posttranslational processing: modulation via monovalent cations
-
Perregaux D.G., and Gabel C.A. Human monocyte stimulus-coupled IL-1beta posttranslational processing: modulation via monovalent cations. Am. J. Physiol. 275 (1998) C1538-C1547
-
(1998)
Am. J. Physiol.
, vol.275
-
-
Perregaux, D.G.1
Gabel, C.A.2
-
65
-
-
0032031392
-
Post-translational processing of murine IL-1: evidence that ATP-induced release of IL-1 alpha and IL-1 beta occurs via a similar mechanism
-
Perregaux D.G., and Gabel C.A. Post-translational processing of murine IL-1: evidence that ATP-induced release of IL-1 alpha and IL-1 beta occurs via a similar mechanism. J. Immunol. 160 (1998) 2469-2477
-
(1998)
J. Immunol.
, vol.160
, pp. 2469-2477
-
-
Perregaux, D.G.1
Gabel, C.A.2
-
66
-
-
0029923974
-
Human monocyte interleukin-1beta posttranslational processing. Evidence of a volume-regulated response
-
Perregaux D.G., Laliberte R.E., and Gabel C.A. Human monocyte interleukin-1beta posttranslational processing. Evidence of a volume-regulated response. J. Biol. Chem. 271 (1996) 29830-29838
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29830-29838
-
-
Perregaux, D.G.1
Laliberte, R.E.2
Gabel, C.A.3
-
67
-
-
0034813135
-
Identification and characterization of a novel class of interleukin-1 post-translational processing inhibitors
-
Perregaux D.G., McNiff P., Laliberte R., Hawryluk N., Peurano H., Stam E., Eggler J., Griffiths R., Dombroski M.A., and Gabel C.A. Identification and characterization of a novel class of interleukin-1 post-translational processing inhibitors. J. Pharmacol. Exp. Ther. 299 (2001) 187-197
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.299
, pp. 187-197
-
-
Perregaux, D.G.1
McNiff, P.2
Laliberte, R.3
Hawryluk, N.4
Peurano, H.5
Stam, E.6
Eggler, J.7
Griffiths, R.8
Dombroski, M.A.9
Gabel, C.A.10
-
68
-
-
9144267257
-
The non-classical export routes: FGF1 and IL-1alpha point the way
-
Prudovsky I., Mandinova A., Soldi R., Bagala C., Graziani I., Landriscina M., Tarantini F., Duarte M., Bellum S., Doherty H., and Maciag T. The non-classical export routes: FGF1 and IL-1alpha point the way. J. Cell Sci. 116 (2003) 4871-4881
-
(2003)
J. Cell Sci.
, vol.116
, pp. 4871-4881
-
-
Prudovsky, I.1
Mandinova, A.2
Soldi, R.3
Bagala, C.4
Graziani, I.5
Landriscina, M.6
Tarantini, F.7
Duarte, M.8
Bellum, S.9
Doherty, H.10
Maciag, T.11
-
69
-
-
0025255629
-
A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence
-
Rubartelli A., Cozzolino F., Talio M., and Sitia R. A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence. EMBO J. 9 (1990) 1503-1510
-
(1990)
EMBO J.
, vol.9
, pp. 1503-1510
-
-
Rubartelli, A.1
Cozzolino, F.2
Talio, M.3
Sitia, R.4
-
70
-
-
0141727395
-
Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis
-
Rudolphi K., Gerwin N., Verzijl N., van der K.P., and van den B.W. Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis. Osteoarthritis Cartilage 11 (2003) 738-746
-
(2003)
Osteoarthritis Cartilage
, vol.11
, pp. 738-746
-
-
Rudolphi, K.1
Gerwin, N.2
Verzijl, N.3
van der, K.P.4
van den, B.W.5
-
71
-
-
0031894316
-
Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice
-
Schielke G.P., Yang G.Y., Shivers B.D., and Betz A.L. Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice. J. Cereb. Blood Flow Metab. 18 (1998) 180-185
-
(1998)
J. Cereb. Blood Flow Metab.
, vol.18
, pp. 180-185
-
-
Schielke, G.P.1
Yang, G.Y.2
Shivers, B.D.3
Betz, A.L.4
-
72
-
-
0032194115
-
Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing
-
Schonbeck U., Mach F., and Libby P. Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing. J. Immunol. 161 (1998) 3340-3346
-
(1998)
J. Immunol.
, vol.161
, pp. 3340-3346
-
-
Schonbeck, U.1
Mach, F.2
Libby, P.3
-
73
-
-
0142188258
-
NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor
-
Seman M., Adriouch S., Scheuplein F., Krebs C., Freese D., Glowacki G., Deterre P., Haag F., and Koch-Nolte F. NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor. Immunity 19 (2003) 571-582
-
(2003)
Immunity
, vol.19
, pp. 571-582
-
-
Seman, M.1
Adriouch, S.2
Scheuplein, F.3
Krebs, C.4
Freese, D.5
Glowacki, G.6
Deterre, P.7
Haag, F.8
Koch-Nolte, F.9
-
74
-
-
3242679672
-
Reanalysis of P2X7 receptor expression in rodent brain
-
Sim J.A., Young M.T., Sung H.Y., North R.A., and Surprenant A. Reanalysis of P2X7 receptor expression in rodent brain. J. Neurosci. 24 (2004) 6307-6314
-
(2004)
J. Neurosci.
, vol.24
, pp. 6307-6314
-
-
Sim, J.A.1
Young, M.T.2
Sung, H.Y.3
North, R.A.4
Surprenant, A.5
-
75
-
-
0036829772
-
The neuroprotective agents chlomethiazole and SB203580 inhibit IL-1beta signalling but not its biosynthesis in rat cortical glial cells
-
Simi A., Porsmyr-Palmertz M., Hjerten A., Ingelman-Sundberg M., and Tindberg N. The neuroprotective agents chlomethiazole and SB203580 inhibit IL-1beta signalling but not its biosynthesis in rat cortical glial cells. J. Neurochem. 83 (2002) 727-737
-
(2002)
J. Neurochem.
, vol.83
, pp. 727-737
-
-
Simi, A.1
Porsmyr-Palmertz, M.2
Hjerten, A.3
Ingelman-Sundberg, M.4
Tindberg, N.5
-
76
-
-
0028970610
-
The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy
-
Singer I.I., Scott S., Chin J., Bayne E.K., Limjuco G., Weidner J., Miller D.K., Chapman K., and Kostura M.J. The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy. J. Exp. Med. 182 (1995) 1447-1459
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1447-1459
-
-
Singer, I.I.1
Scott, S.2
Chin, J.3
Bayne, E.K.4
Limjuco, G.5
Weidner, J.6
Miller, D.K.7
Chapman, K.8
Kostura, M.J.9
-
77
-
-
0035808396
-
Altered cytokine production in mice lacking P2X(7) receptors
-
Solle M., Labasi J., Perregaux D.G., Stam E., Petrushova N., Koller B.H., Griffiths R.J., and Gabel C.A. Altered cytokine production in mice lacking P2X(7) receptors. J. Biol. Chem. 276 (2001) 125-132
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 125-132
-
-
Solle, M.1
Labasi, J.2
Perregaux, D.G.3
Stam, E.4
Petrushova, N.5
Koller, B.H.6
Griffiths, R.J.7
Gabel, C.A.8
-
78
-
-
17644414137
-
The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy
-
Tanga F.Y., Nutile-McMenemy N., and DeLeo J.A. The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 5856-5861
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 5856-5861
-
-
Tanga, F.Y.1
Nutile-McMenemy, N.2
DeLeo, J.A.3
-
79
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
Thornberry N.A., Bull H.G., Calaycay J.R., Chapman K.T., Howard A.D., Kostura M.J., Miller D.K., Molineaux S.M., Weidner J.R., Aunins J., et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 356 (1992) 768-774
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weidner, J.R.9
Aunins, J.10
-
80
-
-
4344627821
-
Endogenous ligands of Toll-like receptors
-
Tsan M.F., and Gao B. Endogenous ligands of Toll-like receptors. J. Leukoc. Biol. 76 (2004) 514-519
-
(2004)
J. Leukoc. Biol.
, vol.76
, pp. 514-519
-
-
Tsan, M.F.1
Gao, B.2
-
81
-
-
0033198510
-
Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor
-
Virginio C., MacKenzie A., North R.A., and Surprenant A. Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor. J. Physiol. 519 Pt 2 (1999) 335-346
-
(1999)
J. Physiol.
, vol.519
, Issue.PART 2
, pp. 335-346
-
-
Virginio, C.1
MacKenzie, A.2
North, R.A.3
Surprenant, A.4
-
82
-
-
0031594354
-
Activation of p38MAPK in microglia after ischemia
-
Walton K.M., DiRocco R., Bartlett B.A., Koury E., Marcy V.R., Jarvis B., Schaefer E.M., and Bhat R.V. Activation of p38MAPK in microglia after ischemia. J. Neurochem. 70 (1998) 1764-1767
-
(1998)
J. Neurochem.
, vol.70
, pp. 1764-1767
-
-
Walton, K.M.1
DiRocco, R.2
Bartlett, B.A.3
Koury, E.4
Marcy, V.R.5
Jarvis, B.6
Schaefer, E.M.7
Bhat, R.V.8
-
83
-
-
0037113928
-
Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice
-
Wang X., Xu L., Wang H., Young P.R., Gaestel M., and Feuerstein G.Z. Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice. J. Biol. Chem. 277 (2002) 43968-43972
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43968-43972
-
-
Wang, X.1
Xu, L.2
Wang, H.3
Young, P.R.4
Gaestel, M.5
Feuerstein, G.Z.6
-
84
-
-
0033603199
-
Dynamic regulation of the proinflammatory cytokine, interleukin-1beta: molecular biology for non-molecular biologists
-
Watkins L.R., Hansen M.K., Nguyen K.T., Lee J.E., and Maier S.F. Dynamic regulation of the proinflammatory cytokine, interleukin-1beta: molecular biology for non-molecular biologists. Life Sci. 65 (1999) 449-481
-
(1999)
Life Sci.
, vol.65
, pp. 449-481
-
-
Watkins, L.R.1
Hansen, M.K.2
Nguyen, K.T.3
Lee, J.E.4
Maier, S.F.5
-
85
-
-
0028170376
-
Structure and mechanism of interleukin-1 beta converting enzyme
-
Wilson K.P., Black J.A., Thomson J.A., Kim E.E., Griffith J.P., Navia M.A., Murcko M.A., Chambers S.P., Aldape R.A., Raybuck S.A., et al. Structure and mechanism of interleukin-1 beta converting enzyme. Nature 370 (1994) 270-275
-
(1994)
Nature
, vol.370
, pp. 270-275
-
-
Wilson, K.P.1
Black, J.A.2
Thomson, J.A.3
Kim, E.E.4
Griffith, J.P.5
Navia, M.A.6
Murcko, M.A.7
Chambers, S.P.8
Aldape, R.A.9
Raybuck, S.A.10
-
86
-
-
0027217131
-
Pyridinyl imidazoles inhibit IL-1 and TNF production at the protein level
-
Young P., McDonnell P., Dunnington D., Hand A., Laydon J., and Lee J. Pyridinyl imidazoles inhibit IL-1 and TNF production at the protein level. Agents Actions 39 Spec No (1993) C67-C69
-
(1993)
Agents Actions
, vol.39
, Issue.Spec No
-
-
Young, P.1
McDonnell, P.2
Dunnington, D.3
Hand, A.4
Laydon, J.5
Lee, J.6
-
87
-
-
10344264453
-
Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway
-
Zhai Y., Shen X.D., O'Connell R., Gao F., Lassman C., Busuttil R.W., Cheng G., and Kupiec-Weglinski J.W. Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J. Immunol. 173 (2004) 7115-7119
-
(2004)
J. Immunol.
, vol.173
, pp. 7115-7119
-
-
Zhai, Y.1
Shen, X.D.2
O'Connell, R.3
Gao, F.4
Lassman, C.5
Busuttil, R.W.6
Cheng, G.7
Kupiec-Weglinski, J.W.8
-
88
-
-
33646117271
-
Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1beta (IL-1beta) in astrocyte cultures
-
Zhang W., Petrovic J.M., Callaghan D., Jones A., Cui H., Howlett C., and Stanimirovic D. Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1beta (IL-1beta) in astrocyte cultures. J. Neuroimmunol. 174 (2006) 63-73
-
(2006)
J. Neuroimmunol.
, vol.174
, pp. 63-73
-
-
Zhang, W.1
Petrovic, J.M.2
Callaghan, D.3
Jones, A.4
Cui, H.5
Howlett, C.6
Stanimirovic, D.7
|