Fluoro-substituted and 13C-labeled styrylbenzene derivatives for detecting brain amyloid plaques

European Journal of Medicinal Chemistry

Volumn 39, Issue 7, 2004, Pages 573-578

  Sato, Kumi ^a   Higuchi, Makoto ^b   Iwata, Nobuhisa ^b   Saido, Takaomi C ^b   Sasamoto, Kazumi ^a  

^a Dojindo Laboratories   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

A ; AD; Alzheimer's disease; amyloid ; Histochemical staining; Magnetic resonance imaging; neurofibrillary tangles; neuropil threads; NFTs; NPs; senile plaques; SPs; Strylbenzenes

Indexed keywords

1 FLUORO 2,5 BIS(3 HYDROXYCARBONYL 4 HYDROXY)STYRYLBENZENE; BENZENE DERIVATIVE; CONTRAST MEDIUM; UNCLASSIFIED DRUG; (E,E) 1 BROMO 2,5 BIS(3 HYDROXYCARBONYL 4 HYDROXY)STYRYLBENZENE ALPHA ALPHA' (13)C(2); (E,E) 1 FLUORO 2,5 BIS (3 HYDROXYCARBONYL 4 HYDROXY)STYRYLBENZENE; (E,E)-1-BROMO-2,5-BIS(3-HYDROXYCARBONYL-4-HYDROXY)STYRYLBENZENE-ALPHA ALPHA'-(13)C(2); (E,E)-1-FLUORO-2,5-BIS-(3-HYDROXYCARBONYL-4-HYDROXY)STYRYLBENZENE; DIAGNOSTIC AGENT; FLUORESCENT DYE; STYRENE DERIVATIVE;

ALZHEIMER DISEASE; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DRUG SYNTHESIS; FLUORESCENCE; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; NEUROFIBRILLARY TANGLE; REACTION ANALYSIS; SENILE PLAQUE; SPECTROFLUOROMETRY; BRAIN; CHEMISTRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; RADIOGRAPHY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ALZHEIMER DISEASE; BRAIN; CONTRAST MEDIA; FLUORESCENCE; FLUORESCENT DYES; HUMANS; MAGNETIC RESONANCE IMAGING; SENILE PLAQUES; STRUCTURE-ACTIVITY RELATIONSHIP; STYRENES;

EID: 3242674405     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2004.02.013     Document Type: Article

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