SIRT1 relays nutritional inputs to the circadian clock through the Sf1 neurons of the ventromedial hypothalamus

Endocrinology (United States)

Volumn 156, Issue 6, 2015, Pages 2174-2184

  Orozco Solis, Ricardo ^a   Ramadori, Giorgio ^b   Coppari, Roberto ^b   Sassone Corsi, Paolo ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

SIRTUIN 1; STEROIDOGENIC FACTOR 1; DNA BINDING PROTEIN; SIRT1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; ZFP162 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CIRCADIAN RHYTHM; DARKNESS; DIET RESTRICTION; FOOD INTAKE; GENE EXPRESSION; LIGHT; MALE; MOLECULAR SENSOR; MOUSE; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; PROTEIN FUNCTION; SUPRACHIASMATIC NUCLEUS; ZONA INCERTA; ANIMAL; BRAIN; GENETICS; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; METABOLISM; NERVE CELL; PHYSIOLOGY;

ANIMALS; BRAIN; CIRCADIAN CLOCKS; DNA-BINDING PROTEINS; MALE; MICE; NEURONS; SIRTUIN 1; TRANSCRIPTION FACTORS; VENTROMEDIAL HYPOTHALAMIC NUCLEUS;

EID: 84930452977     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2014-1805     Document Type: Article

References (58)

1. Möller-Levet CS, Archer SN, Bucca G, et al. Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome. Proc Natl Acad Sci USA. 2013;110(12):E1132-E1141.
2. Markwald RR, Melanson EL, Smith MR, et al. Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain. Proc Natl Acad Sci USA. 2013;110(14):5695-5700.
3. Buxton OM, Cain SW, O'Connor SP, et al. Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption. Sci Transl Med. 2012;4(129):129ra143.
4. Spaeth AM, Dinges DF, Goel N. Effects of experimental sleep restriction on weight gain, caloric intake, and meal timing in healthy adults. Sleep. 2013;36(7):981-990.
5. Rath M, Rovsing L, Møller M. Circadian oscillators in the mouse brain: molecular clock components in the neocortex and cerebellar cortex. Cell Tissue Res. 2014:1-13.
6. Dibner C, Schibler U, Albrecht U. The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu Rev Physiol. 2010;72:517-549.
7. Feillet CA, Mendoza J, Albrecht U, Pevet P, Challet E. Forebrain oscillators ticking with different clock hands. Mol Cell Neurosci. 2008;37(2):209-221.
8. Cermakian N, Sassone-Corsi P. Environmental stimulus perception and control of circadian clocks. Curr Opin Neurobiol. 2002;12(4):359-365.
9. Eckel-Mahan KL. Circadian oscillations within the hippocampus support memory formation and persistence. Front Mol Neurosci. 2012;5:46.
10. Damiola F, Le Minh N, Preitner N, Kornmann B, Fleury-Olela F, Schibler U. Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev. 2000;14(23):2950-2961.
11. Saper CB, Scammell TE, Lu J. Hypothalamic regulation of sleep and circadian rhythms. Nature. 2005;437(7063):1257-1263.
12. Hatori M, Vollmers C, Zarrinpar A, et al. Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell Metab. 2012;15(6):848-860.
13. Stephan FK. The. "Other" circadian system: food as a zeitgeber. J Biol Rhythms. 2002;17(4):284-292.
14. Bechtold DA, Loudon AS. Hypothalamic clocks and rhythms in feeding behaviour. Trends Neurosci. 2013;36(2):74-82.
15. Nam Hye J, Boo K, Kim D, et al. Phosphorylation of LSD1 by PKCα is crucial for circadian rhythmicity and phase resetting. Mol Cell. 2014;53(5):791-805.
16. Crosio C, Cermakian N, Allis CD, Sassone-Corsi P. Light induces chromatin modification in cells of the mammalian circadian clock. Nat Neurosci. 2000;3(12):1241-1247.
17. Orozco-Solis R, Sassone-Corsi P. Epigenetic control and the circadian clock: linking metabolism to neuronal responses. Neuroscience. 2014;264(0):76-87.
18. Dhillon H, Zigman JM, Ye C, et al. Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron. 2006;49(2):191-203.
19. Ramadori G, Fujikawa T, Anderson J, et al. SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance. Cell Metab. 2011;14(3):301-312.
20. Egawa M, Inoue S, Satoh S, Takamura Y, Nagai K, Nakagawa H. Acute and chronic effects of VMH lesions on circadian rhythms in food intake and metabolites. Brain Res Bull. 1993;31(3-4):293-299.
21. Moga MM, Moore RY. Organization of neural inputs to the suprachiasmatic nucleus in the rat. J Comp Neurol. 1997;389(3):508-534.
22. Nakahata Y, Kaluzova M, Grimaldi B, et al. The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell. 2008;134(2):329-340.
23. Chang H-C, Guarente L. SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging. Cell. 2013; 153(7):1448-1460.
24. Bass J, Takahashi JS. Circadian integration of metabolism and energetics. Science. 2010;330(6009):1349-1354.
25. Bellet MM, Orozco-Solis R, Sahar S, Eckel-Mahan K, Sassone-Corsi P. The time of metabolism: NAD+, SIRT1, and the circadian clock. Cold Spring Harb Symp Quant Biol. 2011;76:31-38.
26. Liu Y, Dentin R, Chen D, et al. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature. 2008; 456(7219):269-273.
27. Cakir I, Perello M, Lansari O, Messier NJ, Vaslet CA, Nillni EA. Hypothalamic Sirt1 regulates food intake in a rodent model system. PLoS One. 2009;4(12):e8322.
28. Asher G, Gatfield D, Stratmann M, et al. SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell. 2008; 134(2):317-328.
29. Ramadori G, Fujikawa T, Fukuda M, et al. SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity. Cell Metab. 2010;12(1):78-87.
30. Nelson W, Tong YL, Lee JK, Halberg F. Methods for cosinor-rhythmometry. Chronobiologia. 1979;6(4):305-323.
31. Castillo MR, Hochstetler KJ, Tavernier RJ Jr, Greene DM, Bult-Ito A. Entrainment of the master circadian clock by scheduled feeding. Am J Physiol Regul Integr Comp Physiol. 2004;287(3):R551-R555.
32. Deng XQ, Chen LL, Li NX. The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats. Liver Int. 2007;27(5):708-715.
33. Kohsaka A, Laposky AD, Ramsey KM, et al. High-fat diet disrupts behavioral and molecular circadian rhythms in mice. Cell Metab. 2007;6(5):414-421.
34. Abe H, Honma S, Honma K. Daily restricted feeding resets the circadian clock in the suprachiasmatic nucleus of CS mice. Am J Physiol Regul Integr Comp Physiol. 2007;292(1):R607-R615.
35. Mendoza J, Graff C, Dardente H, Pevet P, Challet E. Feeding cues alter clock gene oscillations and photic responses in the suprachiasmatic nuclei of mice exposed to a light/dark cycle. J Neurosci. 2005;25(6):1514-1522.
36. Persons JE, Stephan FK, Bays ME. Diet-induced obesity attenuates anticipation of food access in rats. Physiol Behav. 1993;54(1):55-64.
37. Froy O. Circadian rhythms, aging, and life span in mammals. Physiology. 2011;26(4):225-235.
38. Shearman LP, Zylka MJ, Weaver DR, Kolakowski LF Jr, Reppert SM. Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei. Neuron. 1997;19(6):1261-1269.
39. Froy O. Circadian rhythms and obesity in mammals. ISRN Obesity. 2012;2012:12.
40. Knutson KL, Van Cauter E. Associations between sleep loss and increased risk of obesity and diabetes. Ann NY Acad Sci. 2008;1129:287-304.
41. McCrimmon RJ, Fan X, Ding Y, Zhu W, Jacob RJ, Sherwin RS. Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus. Diabetes. 2004;53(8):1953-1958.
42. Choi Y-H, Fujikawa T, Lee J, Reuter A, Kim KW. Revisiting the ventral medial nucleus of the hypothalamus: the roles of SF-1 neurons in energy homeostasis. Front Neurosci. 2013;7:71.
43. King BM. The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight. Physiol Behav. 2006;87(2):221-244.
44. Eckel-Mahan KL, Patel VR, de Mateo S, et al. Reprogramming of the circadian clock by nutritional challenge. Cell. 2013;155(7):1464-1478.
45. Mendoza J, Pévet P, Challet E. High-fat feeding alters the clock synchronization to light. J Physiol. 2008;586(24):5901-5910.
46. Chalkiadaki A, Guarente L. High-fat diet triggers inflammation-induced cleavage of SIRT1 in adipose tissue to promote metabolic dysfunction. Cell Metab. 2012;16(2):180-188.
47. Mistlberger RE. Neurobiology of food anticipatory circadian rhythms. Physiol Behav. 2011;104(4):535-545.
48. Ramadori G, Lee CE, Bookout AL, et al. Brain SIRT1: anatomical distribution and regulation by energy availability. J Neurosci. 2008; 28(40):9989-9996.
49. Storch K-F, Weitz CJ. Daily rhythms of food-anticipatory behavioral activity do not require the known circadian clock. Proc Natl Acad Sci USA. 2009;106(16):6808-6813.
50. Ahabrach H, Piedrafita B, Ayad A, et al. Chronic hyperammonemia alters the circadian rhythms of corticosteroid hormone levels and of motor activity in rats. J Neurosci Res. 2010;88(7):1605-1614.
51. Challet E, Caldelas I, Graff C, Pevet P. Synchronization of the molecular clockwork by light- and food-related cues in mammals. Biol Chem. 2003;384(5):711-719.
52. Ribeiro AC, Sawa E, Carren-LeSauter I, LeSauter J, Silver R, Pfaff DW. Two forces for arousal: pitting hunger versus circadian influences and identifying neurons responsible for changes in behavioral arousal. Proc Natl Acad Sci USA. 2007;104(50):20078-20083.
53. Chaix A, Zarrinpar A, Miu P, Panda S. Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges. Cell Metab.20(6):991-1005.
54. Coomans CP, van den Berg SAA, Houben T, et al. Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity. FASEB J. 2013;27(4):1721-1732.
55. Shi S-Q, Ansari TS, McGuinness Owen P, Wasserman David H, Johnson Carl H. Circadian disruption leads to insulin resistance and obesity. Curr Biol. 2013;23(5):372-381.
56. Liu Z, Huang M, Wu X, et al. PER1 phosphorylation specifies feeding rhythm in mice. Cell Rep.7(5):1509-1520.
57. Turek FW, Joshu C, Kohsaka A, et al. Obesity and metabolic syndrome in circadian Clock mutant mice. Science. 2005;308(5724):1043-1045.
58. Sutton GM, Begriche K, Kumar KG, et al. Central nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle. FASEB J. 2010;24(3):862-872.